检索结果-内蒙古大学图书馆

17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013

作者： Li, Sixing Ding, Xiaoyun Guo, Feng Chen, Yuchao Cameron, Craig E. Huang, Tony Jun Department of Engineering Science and Mechanics Penn State University University Park PA 16802 United States Graduate Program Huck Institutes of Life Sciences Penn State University University Park PA 16802 United States Department of Biochemistry and Molecular Biology Pennsylvania State University University Park PA 16802 United States

ISBN: (纸本)9781632666246

In this work, we demonstrate a microfluidic device capable of sorting picoliter water-in-oil droplets into multiple outlets using tunable standing surface acoustic wave (SSAW). Within the SSAW field, water-in-oil droplets experience an acoustic radiation force and are pushed towards the acoustic pressure node. As a result, by tuning the frequency of the SSAW excitation, the positions of the pressure nodes can be changed and droplets can be sorted to five different outlets. With its advantages of simplicity, controllability, versatility, non-invasiveness, and capability to be integrated with other on-chip components such as droplet manipulation and optical detection units, the technique presented here could be valuable for the development of droplet-based micro total analysis systems (μTAS). Copyright © (2013) by the Chemical and Biological Microsystems Society All rights reserved. All rights reserved.

关键词： Acoustic waves

来源：评论

学校读者我要写书评

暂无评论

Effective monitoring of environmental hazardous drug moxifloxacin hydrochloride using silver selenide on octadecyl amine modified reduced graphene oxide composite

引用

Journal of Environmental Chemical engineering 2024年第1期12卷

作者： Hwa, Kuo-Yuan Ganguly, Anindita Graduate Institute of Organic and Polymeric Materials National Taipei University of Technology Taipei China Department of Molecular Science and Engineering National Taipei University of Technology Taipei China International Graduate Program in Energy and Optoelectronic Materials National Taipei University of Technology China

The precise detection of antibiotics is very critical. Here, silver selenide (Ag2Se) nanorods are hydrothermally synthesized and ultrasonically treated with rGO surface modified with octadecylamine (rGO-ODA). The optical, structural, morphological, and functional analysis were performed which revealed the orthorhombic pattern of the P2221 E space group, the crystalline purity of Ag2Se, and the substantial composite formation. The morphological studies revealed nanorod like structure of the Ag2Se material and wrinkled sheets of rGO-ODA. A sensor that detects moxifloxacin hydrochloride (MOXH) antibiotic using the cyclic voltammetry (CV), differential pulse voltammetry (DPV) and UV-Vis absorbance was developed. For DPV analysis, a quite low value for detection limit 12.46 nM was exhibited with 0.199 μM – 425.16 μM linear range, and a sensitivity of 5.0439 μA M−1cm−2. For UV-Vis, the sensor demonstrated a very low limit of detection 17.42 nM over 0.12 μM – 7.7 μM working range. The use of this sensor was validated in real-time analysis with industrial waste water, fish, human blood, and urine samples. The results suggested an excellent rate of analyte recovery and enhanced efficiency for MOXH detection with a potential for commercialization in the future. © 2023

关键词： Nanorods

来源：评论

学校读者我要写书评

暂无评论

Correction: Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer

引用

Cell Death Discovery 2025年第1期11卷 1-2页

作者： Yen-Han Tseng Yuh-Min Chen Tzu-Yi Huang Peter Mu-Hsin Chang Trieu Thi My Tran Yu-Tang Huang Anh Thuc Nguyen Chi-Ying F. Huang Jinghua Tsai Chang Ian Yi-Feng Chang Yi-Tung Chen Hsuan Liu Hao-Wen Hsieh Yue-Li Juang Ying-Chih Chang Department of Chest Medicine Taipei Veterans General Hospital Taipei Taiwan Program in Molecular Medicine College of Life Sciences National Yang Ming Chiao Tung University Taipei Taiwan School of Medicine College of Medicine National Yang Ming Chiao Tung University Taipei Taiwan Institute of Biopharmaceutical Sciences College of Pharmaceutical Sciences National Yang Ming Chiao Tung University Taipei Taiwan Department of Oncology Taipei Veterans General Hospital Taipei Taiwan Institute of Biomedical Sciences Academia Sinica Taipei 11529 Taiwan Biomedical Industry Ph.D. Program College of Life Sciences National Yang Ming Chiao Tung University Taipei 112304 Taiwan Program in Molecular Medicine Taiwan International Graduate Program in Molecular Medicine National Yang Ming Chiao Tung University and Academia Sinica Taipei Taiwan Department of Biochemistry School of Medicine Kaohsiung Medical University Kaohsiung Taiwan Chong Hin Loon Memorial Cancer and Biotherapy Research Center National Yang Ming Chiao Tung University Taipei Taiwan Institute of Medicine Chung Shan Medical University 110 Sec.1 Chien-Kuo N. Road Taichung City 402306 Taiwan Molecular Medicine Research Center Chang Gung University Taoyuan Taiwan Department of Neurosurgery Lin-Kou Medical Center Chang Gung Memorial Hospital Taoyuan Taiwan Department of Cell and Molecular Biology College of Medicine Chang Gung University Taoyuan Taiwan Graduate Institute of Biomedical Sciences College of Medicine Chang Gung University Taoyuan Taiwan Division of Hematology-Oncology Department of Internal Medicine Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan Institute of Clinical Medicine School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan Institute of Biomedical Sciences Mackay Medical College New Taipei City Taiwan Genomics Research Center Academia Sinica Taipei 115 Taiwan Department of Chemical Engineering Stanford University Stanford CA 94305 USA

来源：评论

学校读者我要写书评

暂无评论

Low Threshold Plasmonic Lattice Laser Based on CsPbBr3 Quantum Dots with Directional Emission

Low Threshold Plasmonic Lattice Laser Based on CsPbBr3 Quant...

引用

Pacific Rim Conference on Lasers and Electro-Optics (CLEO/Pacific Rim)

作者： Di Xing Cheng-Chieh Lin Ya-Lun Ho Yang-Chun Lee Mu-Hsin Chen Bo-Wei Lin Chun-Wei Chen Jean-Jacques Delaunay School of Engineering The University of Tokyo Tokyo Japan International Graduate Program of Molecular Science and Technology (NTU-MST) National Taiwan University and Academia Sinica Taipei Taiwan Department of Materials Science and Engineering National Taiwan University Taipei Taiwan Molecular Science and Technology Program Taiwan International Graduate Program (TIGP) Academia Sinica Taipei Taiwan Center of Atomic Initiative for New Materials (AI-MAT) National Taiwan University Taipei Taiwan

Metallic nanoparticles array is served as a promising way to realize on-chip lasers. To achieve high-performance lasers, efficient gain media are also critical. Here, we present a pressure-assisted process for CsPbBr3...

关键词：

来源：评论

学校读者我要写书评

暂无评论

Accelerating the domestication of trees using genomic selection: accuracy of prediction models across ages and environments (vol 193, 617, 2012)

引用

NEW PHYTOLOGIST 2012年第4期193卷 1099-1099页

作者： Resende, M. F. R., Jr. Genetics and Genomics Graduate Program University of Florida PO Box 103610 Gainesville FL 32611 USA School of Forest Resources and Conservation University of Florida PO Box 110410 Gainesville FL 32611 USA Plant Molecular and Cellular Biology Graduate Program University of Florida PO Box 110690 Gainesville FL 32611 USA University of Florida Genetics Institute University of Florida PO Box 103610 Gainesville FL 32611 USA Plant Genetics Laboratory Embrapa – Recursos Genéticos e Biotecnologia Parque Estação Biológica Brasília DF 70770-970 Brazil Graduate Program in Genomic Sciences and Biotechnology Universidade Católica de Brasília–SGAN 916 modulo B Brasília DF 70790-160 Brazil EMBRAPA Forestry Estrada da Ribeira km 111 Caixa Postal 319 Colombo PR 83411-000 Brazil Department of Forest Engineering Universidade Federal de Viçosa Viçosa MG 36571-000 Brazil

• Genomic selection is increasingly considered vital to accelerate genetic improvement. However, it is unknown how accurate genomic selection prediction models remain when used across environments and ages. This knowledge is critical for breeders to apply this strategy in genetic improvement. • Here, we evaluated the utility of genomic selection in a Pinus taeda population of c. 800 individuals clonally replicated and grown on four sites, and genotyped for 4825 single-nucleotide polymorphism (SNP) markers. Prediction models were estimated for diameter and height at multiple ages using genomic random regression best linear unbiased predictor (BLUP). • Accuracies of prediction models ranged from 0.65 to 0.75 for diameter, and 0.63 to 0.74 for height. The selection efficiency per unit time was estimated as 53–112% higher using genomic selection compared with phenotypic selection, assuming a reduction of 50% in the breeding cycle. Accuracies remained high across environments as long as they were used within the same breeding zone. However, models generated at early ages did not perform well to predict phenotypes at age 6 yr. • These results demonstrate the feasibility and remarkable gain that can be achieved by incorporating genomic selection in breeding programs, as long as models are used at the relevant selection age and within the breeding zone in which they were estimated.

关键词： genomic selection genotype by environment interaction model estimation Pinus taeda plant breeding

来源：评论

学校读者我要写书评

暂无评论

Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody (vol 26, pg 1127, 2019)

引用

NATURE STRUCTURAL & molecular BIOLOGY 2020年第2期27卷 222-222页

作者： Yang, Zhi Wang, Haoqing Liu, Albert Z. Gristick, Harry B. Bjorkman, Pamela J. Division of Biology and Biological Engineering California Institute of Technology Pasadena USA Molecular and Cellular Physiology Stanford University Stanford USA Biochemistry Cellular and Molecular Biology Graduate Program Johns Hopkins University School of Medicine Baltimore USA

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Integrated omics analysis on the bacterial community in the anaerobic digestion of chicken manure materials in biogas production farm

引用

Bioresource Technology Reports 2023年 22卷

作者： Lam, Tze-Kang Yu, Chang-Ping Wu, Shih-Hsiung Graduate Institute of Environmental Engineering National Taiwan University Taipei Taiwan Institute of Biological Chemistry Academia Sinica Taipei Taiwan Chemical Biology and Molecular Biophysics Program Taiwan International Graduate Program Academia Sinica Taipei Taiwan Department of Chemistry National Taiwan University Taipei Taiwan

The overall effectiveness of anaerobic digestion is affected by the initial three phases as a result of substrates created for the methanogens to take in. In this study, the bacterial composition of the various chambers in the anaerobic digestion of chicken manure was investigated. Diversity of the microbial community for chicken manure was relatively simpler, consisting mainly of Lactobacillus, compared to the main digestion chambers with a more complex community. Chicken manure only has hydrolysis phase occurring, while the main digesters have the first three phases of anaerobic digestion concurrently occurring. A comparison of the metagenomics versus metaproteomics analysis revealed that the main difference was in the percentage of unknown microorganisms. The quantity of volatile fatty acids detected in each respective chamber suggested the effectiveness of the microorganisms in assimilating the metabolites. Successful integration of these study modes would present a better understanding on anaerobic digestion of complex systems. © 2023

关键词： Anaerobic digestion

来源：评论

学校读者我要写书评

暂无评论

7. 2: Integrated organic semiconductor optoelectronic devices as real-time and indicator-free biosensor

7. 2: Integrated organic semiconductor optoelectronic device...

引用

作者： Chao, Yu-Chiang Yeh, Shih-De Meng, Hsin-Fei Zan, Hsiao-Wen Chang, Gao-Fong Hung, Chen-Hsiung Meng, Tzu-Ching Institute of Physics National Chiao Tung University Hsinchu 300 Taiwan Department of Photonics Institute of Electro-Optical Engineering National Chiao Tung University Hsinchu 300 Taiwan Department of Chemistry National Tsing Hua University Hsinchu 300 Taiwan Molecular Science and Technology Program Taiwan International Graduate Program Academia Sinica Taipei 105 Taiwan Institute of Chemistry Academia Sinica Taipei 105 Taiwan Institute of Biological Chemistry Academia Sinica Taipei 105 Taiwan

A biosensor specific to nitric oxide is realized by integrating an organic light-emitting diode, a photodetector, and a sensing hydrogel film. Two organic filters are also used to reduce the influence of the excitatio... 详细信息

关键词： Biosensors

来源：评论

学校读者我要写书评

暂无评论

Alkyl-thiophene-alkyl linkers to construct double-cable conjugated polymers for single-component organic solar cells

引用

Chinese Chemical Letters 2024年第1期35卷 542-546页

作者： Wenbin Lai Safakath Karuthedath Chengyi Xiao Lei Meng Frédéric Laquai Weiwei Li Yongfang Li Beijing National Laboratory for Molecular Sciences Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China Beijing Advanced Innovation Center for Soft Matter Science and Engineering&State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China King Abdullah University of Science and Technology(KAUST) KAUST Solar Center(KSC)Physical Sciences and Engineering Division(PSE)Material Science and Engineering Program(MSE)Thuwal 23955-6900Kingdom of Saudi Arabia University of Chinese Academy of Sciences Beijing 100049China Institute of Materials Research Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China

In this work,semirigid linkers of the alkyl-thiophene-alkyl structure are developed to construct double-cable *** alkyl units,propyl(C3H6),hexyl(C6H12),and dodecyl(C12H24),are applied as semirigid linkers,yielding three double-cable polymers:PBC6-T,PBC12-T,and PBC24-T,***12-T which uses C6H12-thiophene-C6H12 linkers is found to exhibit the best device efficiency of 5.56%,while PBC6-T and PBC24-T with shorter or longer linkers yield device efficiencies of only 2.65%and 1.09%in single-component organic solar cells(SCOSCs).Further studies reveal that PBC12-T exhibits higher crystallinity and improved charge transport,resulting in better *** work provides an approach to construct double-cable conjugated polymers with long alkyl linkers,and it shows the importance of the linker length for the photovoltaic performance of SCOSCs.

关键词： Double-cable conjugated polymer Single-component organic solar cell Crystallinity Semirigid linkers Alkyl-thiophene-alkyl

来源：评论

学校读者我要写书评

暂无评论

Defining new mechanistic roles for α II spectrin in cardiac function (vol 294, pg 9576, 2019)

引用

JOURNAL OF BIOLOGICAL CHEMISTRY 2019年第42期294卷 15557-15557页

作者： Lubbers, Ellen R. Murphy, Nathaniel P. Musa, Hassan Huang, Claire Yu-Mei Gupta, Rohan Price, Morgan V. Han, Mei Daoud, Georges E. Gratz, Daniel El Refaey, Mona Xu, Xianyao Hoeflinger, Nicole K. Friel, Emma L. Lancione, Peter Wallace, Michael J. Cavus, Omer Simmons, Samantha L. Williams, Jordan L. Skaf, Michel Koenig, Sara N. Janssen, Paul M. L. Rasband, Matthew N. Hund, Thomas J. Mohler, Peter J. From the Dorothy M. Davis Heart and Lung Research Institute and Frick Center for Heart Failure and Arrhythmia. Medical Scientist Training Program. the Departments of Physiology and Cell Biology and. the Department of Neuroscience and Integrative Molecular and Biomedical Sciences Graduate Program Baylor College of Medicine Houston Texas 77030 and. the Department of Biomedical Engineering The Ohio State University Columbus Ohio 432310. Internal Medicine Division of Cardiovascular Medicine The Ohio State University College of Medicine and Wexner Medical Center Columbus Ohio 432310. From the Dorothy M. Davis Heart and Lung Research Institute and Frick Center for Heart Failure and Arrhythmia Peter.Mohler@osumc.edu.

Spectrins are cytoskeletal proteins essential for membrane biogenesis and regulation and serve critical roles in protein targeting and cellular signaling. αII spectrin () is one of two α spectrin genes and αII spectrin dysfunction is linked to alterations in axon initial segment formation, cortical lamination, and neuronal excitability. Furthermore, human αII spectrin loss-of-function variants cause neurological disease. As global αII spectrin knockout mice are embryonic lethal, the roles of αII spectrin in adult heart are unknown and untested. Here, based on pronounced alterations in αII spectrin regulation in human heart failure we tested the roles of αII spectrin in the vertebrate heart. We created a mouse model of cardiomyocyte-selective αII spectrin-deficiency (cKO) and used this model to define the roles of αII spectrin in cardiac function. αII spectrin cKO mice displayed significant structural, cellular, and electrical phenotypes that resulted in accelerated structural remodeling, fibrosis, arrhythmia, and mortality in response to stress. At the molecular level, we demonstrate that αII spectrin plays a nodal role for global cardiac spectrin regulation, as αII spectrin cKO hearts exhibited remodeling of αI spectrin and altered β-spectrin expression and localization. At the cellular level, αII spectrin deficiency resulted in altered expression, targeting, and regulation of cardiac ion channels Na1.5 and K4.3. In summary, our findings define critical and unexpected roles for the multifunctional αII spectrin protein in the heart. Furthermore, our work provides a new animal model to study the roles of αII spectrin in the cardiomyocyte.

关键词： adaptor protein ankryin cardiovascular disease cytoskeleton heart heart failure ion channel spectrin

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：