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2009 22nd IEEE International Symposium on computer-Based Medical Systems, CBMS 2009

作者： Sobieranski, Antonio Carlos Neto, Sylvio Luiz Mantelli Coser, Leandro Comunello, Eros Von Wangenheim, Aldo Cargnin-Ferreira, Eduardo Di Giunta, Gabriella LAPIX Laboratory of Image Processing and Computer Graphics UFSC Federal University of Santa Catarina Brazil CPTEC Center for Weather Forecasts and Environment Studies INPE - Brazilian Institute for Space Research Brazil EGC Knowledge Engineering Department UFSC - Federal University of Santa Catarina Brazil MCA Graduate Program in Applied Computer Science UNIVALI - Itajai Valley University Brazil Laboratory of Histological Markers Department of Biology Embriology and Genetics UFSC - Federal University of Santa Catarina Brazil Pathology Service UFSC - Federal University of Santa Catarina Brazil

ISBN: (纸本)9781424448784

This paper presents a semiautomatic method for the identification of immunohistochemical (IHC) staining in digitized samples. The user trains the system by selecting on a sample image some typical positive stained regions that will be used as a reference for the construction of a distance metric. In this learning process, the global optimum is obtained by induction employing higher polynomial terms of the Mahalanobis distance, extracting nonlinear features of the IHC pattern distributions. The results of the proposed method showed a high correlation to a pathologist's manual analysis, which was used as a golden standard, presenting a more robust discrimination between stained and non-stained areas with little bias. © 2009 IEEE.

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Hardware Architecture for Particle Swarm Optimization Using Floating-Point Arithmetic

Hardware Architecture for Particle Swarm Optimization Using ...

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International Conference on Intelligent Systems Design and Applications (ISDA)

作者： Daniel M. Muñoz Arboleda Carlos H. Llanos Leandro dos_S. Coelho Mauricio Ayala-Rincón Department of Mechanical Engineering University of Brasilia Brasília Brazil Industrial and Systems Engineering Graduate Program Pontificial Catholic University of Paraná Curitiba Brazil Departments of Computer Science and Mathematics University of Brasilia Brasília Brazil

High computational cost for solving large engineering optimization problems point out the design of parallel optimization algorithms. Population based optimization algorithms provide parallel capabilities that can be explored by their implementations done directly in hardware. This paper presents a hardware implementation of particle swarm optimization algorithms using an efficient floating-point arithmetic which performs the computations with high precision. All the architectures are parameterizable by bit-width, allowing the designer to choose the suitable format according to the requirements of the optimization problem. Synthesis and simulation results demonstrate that the proposed architecture achieves satisfactory results obtaining a better performance in therms of elapsed time than conventional software implementations.

关键词： Hardware Particle swarm optimization Floating-point arithmetic computer architecture Design optimization Computational efficiency Design engineering Algorithm design and analysis High performance computing Computational modeling

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Time Series Mining Approach for Noninvasive Intracranial Pressure Assessment: An Investigation of Different Regularization Techniques

Time Series Mining Approach for Noninvasive Intracranial Pre...

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computer science and Information Engineering, CSIE, WRI World Congress on FLAGGED

作者： Shaozhi Wu Peng Xu Shadnaz Asgari Marvin Bergsneider Xiao Hu Biomedical Engineering Graduate Program Henry Samueli School of Engineering and Applied Science University of California Los Angeles USA Neural Systems and Dynamics Laboratory Department of Neurosurgery the David Geffen School of Medicine University of California Los Angeles USA School of Computer Science and Engineering University of Electronic Science and Technology Chengdu China

A data mining framework has been proposed to estimate intracranial pressure (ICP) non-invasively in our previous work. In the corresponding approach, the feature vector extracted from arterial blood pressure (ABP) and flow velocity (FV) is translated to the estimated errors by the mapping function for each entry in the database. In this paper, three different mapping function solutions, linear least squares (LLS), truncated singular value decomposition (TSVD) and standard Tikhonov regularization (STR) are systemically tested to compare the possible effects of different solutions on the non-invasive ICP estimation. The conducted comparison demonstrated that the selection of mapping function solution actually influences the estimation. Among the tested three solutions for mapping function, TSVD and STR show better ICP estimation performance with smaller ICP errors than LLS.

关键词： Cranial pressure Data mining Biomedical engineering Data engineering Spatial databases computer science Feature extraction Arterial blood pressure Biomedical measurements Laboratories

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An agent framework to support sensor networks' setup and adaptation

An agent framework to support sensor networks' setup and ada...

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International Multiconference on computer science and Information Technology, IMCSIT

作者： Edison Pignaton de Freitas Flávio Rech Wagner Tales Heimfarth Carlos Eduardo Pereira Armando Morado Ferreira Tony Larsson IDE - Halmstad University Sweden Computer Science Department UFLA Lavras Brazil Institute of Informatics UFRGS Porto Alegre Brazil Defense Engineering Graduate Program Military Institute of Engineering Rio de Janeiro Brazil IDE - Halmstad University Halmstad Sweden

Sensor networks are being used in several emerging applications not even imagined some years ago due to advances in sensing, computing, and communication techniques. However, these advances also pose various challenges that must be faced. One important challenge is related to the autonomous capability needed to setup and adapt the networks, which decentralizes the control of the network, saving communication and energy resources. Middleware technology helps in addressing this kind of problem, but there is still a need for additional solutions, particularly considering dynamic changes in users' requirements and operation conditions. This paper presents an agent-based framework acting as an integral part of a middleware to support autonomous setup and adaptation of sensor networks. It adds interoperability among heterogeneous nodes in the network, by means of autonomous behavior and reasoning. These features also address the needs for system setup and adaptations in the network, reducing the communication overhead and decentralizing the decision making mechanism. Additionally, preliminary results are also presented.

关键词： Middleware Image sensors computer networks Communication system control Energy resources Decision making

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Gratings on porous silicon structures for sensing applications

Gratings on porous silicon structures for sensing applicatio...

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Conference on Lasers and Electro-Optics, CLEO 2009

作者： Liscidini, M. Wei, X. Kang, C. Rong, G. Retterer, S.T. Patrini, M. Sipe, J.E. Weiss, S.M. Department of Physics University of Toronto 60 St. George St Toronto M5S 1A7 ON Canada Department of Electrical Engineering and Computer Science Vanderbilt University Nashville TN 37235 United States Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak Ridge TN 37831 United States CNISM and Dipartimento di Fisica 'A. Volta' Università degli Studi di Pavia via Bassi 6 27100 Pavia Italy

We investigate the use of gratings on porous silicon structures for sensing applications. Examples of two classes of systems are studied: grating-coupled waveguide biosensors, and diffraction-based biosensors. © ... 详细信息

ISBN: (纸本)9781557528698

关键词： Biosensors

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Identification of cell cycle-related regulatory motifs using a kernel canonical correlation analysis

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BMC Genomics 2009年第SUPPL. 3期10卷 1-10页

作者： Rhee, Je-Keun Joung, Je-Gun Chang, Jeong-Ho Fei, Zhangjun Zhang, Byoung-Tak Graduate Program in Bioinformatics Seoul National University Seoul 151-744 South Korea Center for Biointelligence Technology (CBIT) Seoul National University Seoul 151-744 South Korea Boyce Thompson Institute for Plant Research Cornell University Ithaca NY 14853 United States Konan Technology Inc Seoul 135-080 South Korea USDA Robert W. Holley Center for Agriculture and Health Ithaca NY 14853 United States School of Computer Science and Engineering Seoul National University Seoul 151-744 South Korea

Background: Gene regulation is a key mechanism in higher eukaryotic cellular processes. One of the major challenges in gene regulation studies is to identify regulators affecting the expression of their target genes in specific biological processes. Despite their importance, regulators involved in diverse biological processes still remain largely unrevealed. In the present study, we propose a kernel-based approach to efficiently identify core regulatory elements involved in specific biological processes using gene expression profiles. Results: We developed a framework that can detect correlations between gene expression profiles and the upstream sequences on the basis of the kernel canonical correlation analysis (kernel CCA). Using a yeast cell cycle dataset, we demonstrated that upstream sequence patterns were closely related to gene expression profiles based on the canonical correlation scores obtained by measuring the correlation between them. Our results showed that the cell cycle-specific regulatory motifs could be found successfully based on the motif weights derived through kernel CCA. Furthermore, we identified co-regulatory motif pairs using the same framework. Conclusion: Given expression profiles, our method was able to identify regulatory motifs involved in specific biological processes. The method could be applied to the elucidation of the unknown regulatory mechanisms associated with complex gene regulatory processes. © 2009 Rhee et al;licensee BioMed Central Ltd.

关键词： Canonical Correlation Analysis Regulatory Motif Upstream Sequence Gene Expression Dataset Yeast Cell Cycle

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Comparison of Different Approaches to ICP Dominated Pulse Extraction

Comparison of Different Approaches to ICP Dominated Pulse Ex...

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International Conference on Bioinformatics and Biomedical Engineering (ICBBE)

作者： Peng Xu Shaozhi Wu Shadnaz Asgari Magdalena Kasprowicz Marvin Bergsneider Xiao Hu Center of Neuroinformatics School of Life Science and Technology University of Electronic Science and Technology Chengdu China Neural Systems and Dynamics Laboratory Department of Neurosurgery the David Geffen School of Medicine University of California Los Angeles USA School of Computer Science and Engineering University of Electronic Science and Technology Chengdu China Biomedical Engineering Graduate Program Henry Samueli School of Engineering and Applied Science University of California Los Angeles USA University of California Los Angeles Los Angeles CA US

Changes of ICP waveform morphology are characterized with different patients' states like hypertension, hydrocephalus and traumatic brain injury etc. Morphological clustering and analysis of ICP pulse (MOCAIP) approach is recently developed to extract ICP morphology feature, in which hierarchical clustering is used to extract the dominated pulse. In this paper, we evaluate the feasibility of using principle component analysis (PCA) and independent component analysis (ICA) to extract dominated pulse. The comparative study among clustering, PCA and ICP based approaches shows that PCA approach may be an alternative of clustering approach to extract dominated pulse in a faster fashion when dataset is of large size.

关键词： Independent component analysis Morphology Principal component analysis Biomedical engineering Feature extraction Electrocardiography Tellurium Hypertension Data mining Laboratories

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Identification of cell cycle-related regulatory motifs using a kernel canonical correlation analysis

Identification of cell cycle-related regulatory motifs using...

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8th International Conference on Bioinformatics: Computational Biology, InCoB 2009

作者： Rhee, Je-Keun Joung, Je-Gun Chang, Jeong-Ho Fei, Zhangjun Zhang, Byoung-Tak Graduate Program in Bioinformatics Seoul National University Seoul 151-744 Korea Republic of Seoul National University Seoul 151-744 Korea Republic of Boyce Thompson Institute for Plant Research Cornell University Ithaca NY 14853 United States Konan Technology Inc. Seoul 135-080 Korea Republic of USDA Robert W. Holley Center for Agriculture and Health Ithaca NY 14853 United States School of Computer Science and Engineering Seoul National University Seoul 151-744 Korea Republic of

关键词： Gene expression

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Assembly of CdSeS(ZnS) quantum dots in langmuir films with tertiary alkyl phosphine ligands

Assembly of CdSeS(ZnS) quantum dots in langmuir films with t...

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Nanotechnology - General - 214th ECS Meeting/PRiME 2008

作者： Giles, Alexander J. Pagan, J. Patel, K. Stokes, E.B. Nanoscale Science Graduate Program Department of Chemistry University of North Carolina at Charlotte 9201 University City Boulevard Charlotte NC 28223 United States Dot Metrics Technologies Charlotte Research Institute University of North Carolina at Charlotte 9201 University City Boulevard Charlotte NC 28223 United States Department of Electrical and Computer Engineering University of North Carolina at Charlotte 9201 University City Boulevard Charlotte NC 28223 United States Center for Optoelectronics and Optical Communications University of North Carolina al Charlotte 9201 University City Boulevard Charlotte NC 28223 United States

ISBN: (纸本)9781615672998

The focus of this paper is to describe studies on pre-prepared hydrophobic CdSeS(ZnS) quantum dots (QDs) at the air-water interface. Surface pressure-area (π-A) isotherms were extensively studied using QDs capped with either trioclylphosphine oxide or triethylphosphine oxide. The role of these two different ligands on monolayer behavior and thin film quality has been investigated using the Langmuir-Blodgett (LB) technique. The thin films were characterized by scanning electron microscopy (SEM), fluorescence spectroscopy, and UV-vis spectroscopy. ©The Electrochemical Society.

关键词： Cadmium compounds

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Improving bilateral negotiation with evolutionary learning

Improving bilateral negotiation with evolutionary learning

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2008 12th International Conference on computer Supported Cooperative Work in Design, CSCWD

作者： Romanhuki, Emerson Fuckner, Marcio Enembreck, Fabrício Ávila, Bráulio Scalabrin, Edson E. PUCPR Pontifical Catholic University of Parana Graduate Program on Applied Computer Science Curitiba PR Brazil

ISBN: (纸本)9781424416509

This paper proposes an approach to generate offers and counter-offers in a bilateral negotiation process between cognitive agents with the learning machine capacities. The approach is configured, as each participant of a negotiation process improve their satisfaction degree, gaining knowledge from prior experience, i.e., in the next negotiation session, each participant can individually use this knowledge to redefine the configuration parameters of strategies and tactics to generate offers and counter-offers. Each agent refines their strategies using a genetic algorithm application based on the historical offers and counter-offer exchanges dataset. This context can lead to a new dimension in CSCW System Development. This approach was tested in a simulated bilateral negotiation environment, which involved, for example, a buyer agent and a seller agent. The discussions about the results confront different negotiation sessions comparing agents provided with strategy and tactics reconfiguration capabilities and agents using static strategies and tactics. © 2008 IEEE.

关键词： Genetic algorithms

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