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Advanced Solid-State Photonics, ASSP 2010

作者： Kalaycioǧlu, Hamit Oktem, Bulent Ömer Ilday, F. Department of Physics Bilkent University 06800 Ankara Turkey Material Science and Nanotechnology Graduate Program Bilkent University 06800 Ankara Turkey

We report a 1-MHz robust, all-fiber amplifier-oscillator system. Amplified pulses of 3 μJ are externally compressed to 140 fs. The highest peak power from an integrated fiber source, up to 50 kW, is obtained. © ... 详细信息

ISBN: (纸本)9781557528803

关键词： Fiber amplifiers

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Biomedical data and AI

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science China Life sciences 2025年第5期68卷 1536-1540页

作者： Hao Xu Shibo Zhou Zefeng Zhu Vincenzo Vitelli Liangyi Chen Ziwei Dai Ning Yang Luhua Lai Shengyong Yang Sergey Ovchinnikov Zhuoran Qiao Sirui Liu Chen Song Jianfeng Pei Han Wen Jianfeng Feng Yaoyao Zhang Zhengwei Xie Yang-Yu Liu Zhiyuan Li Fulai Jin Hao Li Mohammad Lotfollahi Xuegong Zhang Ge Yang Shihua Zhang Ge Gao Pulin Li Qi Liu Jing-Dong Jackie Han Peking-Tsinghua Center for Life Sciences (CLS) Academy for Advanced Interdisciplinary StudiesPeking University Center for Quantitative Biology (CQB) Academy for Advanced Interdisciplinary StudiesPeking University Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program Academy for Advanced Interdisciplinary StudiesPeking University Department of Physics University of Chicago School of Life Sciences Southern University of Science and Technology Peking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies College of Chemistry and Molecular Engineering Peking University Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan University Department of Biology Massachusetts Institute of Technology Lambic Therapeutics Inc. Changping Laboratory Al for Science Institute Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence Fudan University Department of Obstetrics and Gynecology West China Second University HospitalSichuan University Peking University International Cancer Institute and Peking University-Yunnan Baiyao International Medical Institute and State Key Laboratory of Natural and Biomimetic Drugs Department of Molecular and Cellular PharmacologySchool of Pharmaceutical SciencesPeking University Health Science CenterPeking University Channing Division of Network Medicine Department of MedicineBrigham and Women's Hospital and Harvard Medical School Center for Artificial Intelligence and Modeling the Carl R.Woese Institute for Genomic BiologyUniversity of Illinois Urbana-Champaign Department of Genetics and Genome Sciences School of Medicine and Department of Computer and Data Sciences and Department of Population and Quantitative Health SciencesCase Western Reserve University Department of Biochemistry and Biophysics University of California Sanger Institute Department of Automation Tsinghua University State Key Laboratory of Multimodal Artificial Intelligence Systems I

The development of artificial intelligence(AI) and the mining of biomedical data complement each other. From the direct use of computer vision results to analyze medical images for disease screening, to now integrating biological knowledge into models and even accelerating the development of new AI based on biological discoveries, the boundaries of both are constantly expanding, and their connections are becoming closer.

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Real-time optimization using gradient adaptive selection and classification from infrared sensors measurement for esterification oleic acid with glycerol

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International Journal of Intelligent Computing and Cybernetics 2017年第2期10卷 130-144页

作者： Iwan Aang Soenandi Taufik Djatna Ani Suryani Irzaman Post Graduate Program of Agro-industrial Technology Bogor Agricultural UniversityBogorIndonesia and Faculty of Engineering and Computer ScienceKrida Wacana Christian UniversityJakartaIndonesia Post Graduate Program of Agro-industrial Technology Bogor Agricultural UniversityBogorIndonesia Department of Physics Faculty of Mathematics and Natural SciencesBogor Agricultural UniversityBogorIndonesia

Purpose-The production of glycerol derivatives by the esterification process is subject to many constraints related to the yield of the production target and the lack of process *** accurate monitoring and controlling of the process can improve production yield and *** purpose of this paper is to propose a real-time optimization(RTO)using gradient adaptive selection and classification from infrared sensor measurement to cover various disturbances and uncertainties in the ***/methodology/approach-The integration of the esterification process optimization using self-optimization(SO)was developed with classification process was combined with necessary condition optimum(NCO)as gradient adaptive selection,supported with laboratory scaled medium wavelength infrared(mid-IR)sensors,and measured the proposed optimization system indicator in the batch *** Process Modeling and Notation(BPMN 2.0)was built to describe the tasks of SO workflow in collaboration with NCO as an abstraction for the conceptual ***,Stateflow modeling was deployed to simulate the three states of gradient-based adaptive control combined with support vector machine(SVM)classification and Arduino microcontroller for ***-This new method shows that the real-time optimization responsiveness of control increased product yield up to 13 percent,lower error measurement with percentage error 1.11 percent,reduced the process duration up to 22 minutes,with an effective range of stirrer rotation set between 300 and 400 rpm and final temperature between 200 and 210℃ which was more efficient,as it consumed less *** limitations/implications-In this research the authors just have an experiment for the esterification process using glycerol,but as a development concept of RTO,it would be possible to apply for another chemical reaction or *** implications-This research introduces new development of an RTO approach to optimal con

关键词： Gradient technique Infrared sensor Real-time optimization Simulation and modelling Support vector machine

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Amplification of enzymatic and microbial fuel cells using organic electrochemical transistors

Device

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Device 2025年

作者： Saxena, Ravindra Zhang, Xu Cai, Rong Suggs, Olivia Bruggeman, Chase Hickey, David P. Ajo-Franklin, Caroline M. Verduzco, Rafael Applied Physics Graduate Program Smalley-Curl Institute Rice University Houston 77005 TX United States Department of Biosciences Rice University Houston 77005 TX United States Department of Chemical Engineering and Materials Science Michigan State University East Lansing 48824 MI United States Department of Bioengineering Rice University Houston 77005 TX United States Department of Chemical and Biomolecular Engineering Rice University Houston 77005 TX United States Rice Advanced Materials Institute Rice University Houston 77005 TX United States

Organic electrochemical transistors (OECTs) are thin-film devices operated in aqueous and biological environments for sensing chemicals and biomolecules. However, most sensor configurations involve introducing the target biomolecule directly in the OECT device. This has drawbacks because it may not be possible to have an electrolyte compatible with the target biomolecule or an environment optimal for the OECT. Here, we demonstrate a general and modular approach to building electrochemical sensors by coupling OECTs electronically with either an enzymatic fuel cell (EFC) or microbial fuel cell (MFC). We demonstrate that this modular approach can amplify currents by three orders of magnitude and enhance the signal-to-noise ratio. We also show that the power generated by the fuel cell can help tune the sensor's response for different applications. This work demonstrates a simple and versatile approach for amplifying currents from MFCs and EFCs useful for the development of bioelectronic sensors. © 2025 The Authors

关键词： amplification biosensors DTI-3: Develop electro-active bacteria enzymatic fuel cells microbial fuel cells organic electrochemical transistors power

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Enhancing the Electrochemical Activity of 2D Materials Edges through Oriented Electric Fields

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ACS Nano 2024年第30期18卷 19828-19835页

作者： Wang, Hao Chen, Ding-Rui Lin, You-Chen Lin, Po-Han Chang, Jui-Teng Muthu, Jeyavelan Hofmann, Mario Hsieh, Ya-Ping Institute of Atomic and Molecular Sciences Academia Sinica Taipei10617 Taiwan Department of Physics National Taiwan University Taipei10617 Taiwan International Graduate Program of Molecular Science and Technology National Taiwan University Taipei10617 Taiwan Molecular Science and Technology Program Taiwan International Graduate Program Academia Sinica Taipei10617 Taiwan Department of Low Dimensional Systems J. Heyrovský Institute of Physical Chemistry Prague18200 Czech Republic

The edges of 2D materials have emerged as promising electrochemical catalyst systems, yet their performance still lags behind that of noble metals. Here, we demonstrate the potential of oriented electric fields (OEFs) to enhance the electrochemical activity of 2D materials edges. By atomically engineering the edge of a fluorographene/graphene/MoS2 heterojunction nanoribbon, strong and localized OEFs were realized as confirmed by simulations and spatially resolved spectroscopy. The observed fringing OEF results in an enhancement of the heterogeneous charge transfer rate between the edge and the electrolyte by 2 orders of magnitude according to impedance spectroscopy. Ab initio calculations indicate a field-induced decrease in the reactant adsorption energy as the origin of this improvement. We apply the OEF-enhanced edge reactivity to hydrogen evolution reactions (HER) and observe a significantly enhanced electrochemical performance, as evidenced by a 30% decrease in Tafel slope and a 3-fold enhanced turnover frequency. Our findings demonstrate the potential of OEFs for tailoring the catalytic properties of 2D material edges toward future complex reactions. © 2024 The Authors. Published by American Chemical Society.

关键词： Electric fields

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Electron spin dynamics guide cell motility

arXiv

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arXiv 2025年

作者： Wang, Kai Gilmer, Gabrielle Araña, Matheus Cândia Iijima, Hirotaka Bergmann, Juliana Woollard, Antonio Mesits, Boris McGraw, Meghan Zoltowski, Brian Cappellaro, Paola Ungar, Alex Pekker, David Waldeck, David H. Saxena, Sunil Lloyd, Seth Ambrosio, Fabrisia Discovery Center for Musculoskeletal Recovery Schoen Adams Research Institute at Spaulding BostonMA United States Department of Physical Medicine & Rehabilitation Spaulding Rehabilitation Hospital BostonMA United States Department of Physical Medicine & Rehabilitation Harvard Medical School BostonMA United States Cellular and Molecular Pathology Graduate Program University of Pittsburgh PittsburghPA United States Medical Scientist Training Program School of Medicine University of Pittsburgh PittsburghPA United States École Polytechnique Institut Polytechnique de Paris Palaiseau France Department of Physics & Astronomy University of Pittsburgh PittsburghPA United States Department of Chemistry Southern Methodist University DallasTX United States Department of Nuclear Science and Engineering Massachusetts Institute of Technology CambridgeMA02139 United States Department of Physics Massachusetts Institute of Technology CambridgeMA02139 United States Department of Chemistry University of Pittsburgh PittsburghPA United States Department of Mechanical Engineering Massachusetts Institute of Technology BostonMA United States

Diverse organisms exploit the geomagnetic field (GMF) for migration. Migrating birds employ an intrinsically quantum mechanical mechanism for detecting the geomagnetic field: absorption of a blue photon generates a radical pair whose two electrons precess at different rates in the magnetic field, thereby sensitizing cells to the direction of the GMF. In this work, using an in vitro injury model, we discovered a quantum-based mechanism of cellular migration. Specifically, we show that migrating cells detect the GMF via an optically activated, electron spin-based mechanism. Cell injury provokes acute emission of blue photons, and these photons sensitize muscle progenitor cells to the magnetic field. We show that the magnetosensitivity of muscle progenitor cells is (a) activated by blue light, but not by green or red light, and (b) disrupted by the application of an oscillatory field at the frequency corresponding to the energy of the electron-spin/magnetic field interaction. A comprehensive analysis of protein expression reveals that the ability of blue photons to promote cell motility is mediated by activation of calmodulin calcium sensors. Collectively, these data suggest that cells possess a light-dependent magnetic compass driven by electron spin dynamics. © 2025, CC BY.

关键词： Spin dynamics

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The effectiveness of mobile learning role play game (rpg) maker mv in improving students' critical thinking ability 6

The effectiveness of mobile learning role play game (rpg) ma...

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6th International Conference on Mathematics, science, and Education, ICMSE 2019

作者： Rasyid, A. Iswari, R.I. Marwoto, P. Rinto, R. Post-Graduate Program Universitas Negeri Semarang Indonesia Biology Education Program Universitas Majalengka Indonesia Department of Physics Faculty of Mathematics and Natural Science Universitas Negeri Semarang Indonesia

The aim of this research were to improve students' critical thinking and to know students' responses in applying mobile learning RPG-based maker MV in Ecosystem learning. This research is experimental research by using quasi-experimental design with Randomized control-Group Pretest Posttest. The data was taken qualitatively by using observation results during students' learning, students' response questionnaire in experiencing mobile learning RPG based maker MV, and quantitative data of students' critical thinking ability. The research findings showed (1) applying mobile learning RPG based maker MV had medium level, (2) Mobile learning RPG maker MV had improved students' critical thinking, and (3) Students' result after using this aplication of Ecosystem learning system in a good level or in the highest score. © Published under licence by IOP Publishing Ltd.

关键词： Students

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Dielectric Properties of a Ferroelectric Nematic Material: Quantitative Test of the Polarization-Capacitance Goldstone Mode

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Physical Review Letters 2024年第3期133卷 038101-038101页

作者： Alex Adaka Mojtaba Rajabi Nilanthi Haputhantrige Samuel Sprunt Oleg D. Lavrentovich Antal Jákli Materials Science Graduate Program Advanced Materials and Liquid Crystal Institute Department of Physics

The recently discovered ferroelectric nematic (NF) liquid crystals (LC) have been reported to show an extraordinarily large value of the real part of the dielectric constant (ϵ′>103) at low frequencies. However, it was argued by Clark et al. in Phys. Rev. Res. 6, 013195 (2024) that what was measured was the capacitance of the insulating layer at LC or electrode surface and not that of the liquid crystal. Here we describe the results of dielectric spectroscopy measurements of an NF material in cells with variable thickness of the insulating layers. Our measurements quantitatively verify the model by Clark et al. Additionally, our measurements in cells with bare conducting indium tin oxide surface provide a crude estimate of ϵ⊥∼102 in the NF phase.

关键词： Dielectric properties Electronic materials Ferroelectricity Functional materials Liquid crystals

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Real-time data acquisition incorporating high-speed software correlator for single-molecule spectroscopy

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Journal of Microscopy 2009年第3期234卷 302-310页

作者： Yang, L.-L. Lee, H.-Y. Wang, M.-K. Lin, X.-Y. Hsu, K.-H. Chang, Y.-R. Fann, W. White, J.D. Department of Physics National Taiwan University Taipei Taiwan Institute of Atomic and Molecular Sciences Academia Sinica Taipei Taiwan Department of Electrical Engineering Yuan Ze University Taoyuan Taiwan Nano Science and Technology Program Taiwan International Graduate Program Academia Sinica Taipei Taiwan

Summary Single-molecule spectroscopy and detection are powerful techniques for the study of single fluorescent particles and their interaction with their environment. We present a low-cost system for simultaneous real-time acquisition, storage of inter-photon arrival times and the calculation and display of the fluorescence time trace, autocorrelation function and distribution of delays histogram for single-molecule experiments. From a hardware perspective, in addition to a multi-core computer, only a standard low-cost counting board is required as processing is software-based. Software is written in a parallel programming environment with time crucial operations coded in ANSI-C. Crucial to system performance is a simple and efficient real-time autocorrelation algorithm (acf) optimized for the count rates (approximately 104 cps) encountered in single-molecule experiments. The algorithm's time complexity is independent of temporal resolution, which is maintained at all time delays. The system and algorithm's performance was validated by duplicating the signal from the photon detector and sending it to both the ordinary counter board and a commercial correlator simultaneously. The data acquisition system's robustness under typical single-molecule experimental conditions was tested by observing the diffusion of Rhodamine 6G molecules in deionized water. © 2009 The Royal Microscopical Society.

关键词： Fluorescence

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New muonic He atom HFS measurements at J-PARC MUSE

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Interactions 2024年第1期245卷 1-6页

作者： Goto, Yu Fukumura, Seiso Strasser, Patrick Ino, Takashi Iwai, Ryoto Kanda, Sohtaro Kawamura, Shiori Kitaguchi, Masaaki Nishimura, Shoichiro Oku, Takayuki Okudaira, Takuya Shimizu, Hirohiko M. Shimomura, Koichiro Tada, Hiroki Torii, Hiroyuki A. Department of Physics Nagoya University Nagoya Japan Tsukuba Japan Materials and Life Science Division J-PARC Center Tokai Japan Materials Structure Science Program Graduate Institute for Advanced Studies SOKENDAI Tsukuba Japan Kobayashi-Maskawa Institute Nagoya University Nagoya Japan Tokai Japan Graduate School of Science and Engineering Ibaraki University Mito Japan School of Science The University of Tokyo Tokyo Japan

Muonic He (μHe) is a hydrogen-like atom composed of a helium atom with one of its electrons replaced by a negative muon. Measurements of the ground-state hyperfine structure (HFS) interval of the μHe atom is a sensitive tool to test the three-body atomic system, bound-state quantum electrodynamics (QED) theory, and determine fundamental constants of the negative muon magnetic moment and mass. It allows a test of the CPT theorem in muons by comparing these constants with positive muons. Precise measurements of the ground-state HFS interval using a microwave magnetic resonance technique are now in progress at J-PARC by the MuSEUM collaboration. Furthermore, a new experimental approach to recover the muon polarization lost during the muon cascade process is being investigated by repolarizing μHe atoms using a spin-exchange optical pumping (SEOP) technique. The first laser repolarization experiment was recently performed. An overview of the different features of these new μHe atom HFS measurements and the latest results are presented. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.

关键词： Atoms

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