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17th Asian Conference on Computer Vision, ACCV 2024

作者： Viriyasaranon, Thanaporn Ma, Serie Choi, Jang-Hwan Department of Computational Medicine Graduate Program in System Health Science and Engineering Ewha Womans University Seoul Korea Republic of Division of Mechanical and Biomedical Engineering Graduate Program in System Health Science and Engineering Ewha Womans University Seoul Korea Republic of Department of Artificial Intelligence Ewha Womans University Seoul Korea Republic of

ISBN: (纸本)9789819609000

The precise detection of cephalometric landmarks on two-dimensional (2D) radiographs or three-dimensional (3D) computed tomography (CT) images is a fundamental step in various medical fields, especially in research on orthodontics and maxillofacial surgery. Deep learning-based detectors have demonstrated remarkable accuracy in 2D cephalometric analysis, whereas conventional single-view approaches are limited by their reliance on information from a single perspective. This study proposes GeoRefineNet, a novel multistage framework that leverages information from multiple CT scans acquired at various angles. By incorporating geometric knowledge through a 3D heatmap reconstruction process, GeoRefineNet improves robustness, accuracy, and adaptability to various cephalometric configurations. The proposed framework predicts 3D landmark positions on CT images, effectively addressing challenges associated with high-dimensional input data and limited training examples. GeoRefineNet surpasses the existing state-of-the-art models in the 2D and 3D domains, as demonstrated by its superior performance on numerical and clinical datasets. These findings indicate that GeoRefineNet offers a promising avenue for improving the accuracy and reliability of cephalometric landmark detection fostering further advances in clinical diagnosis and treatment planning. Our code is available at https://***/Thanaporn09/***. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Computerized tomography

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Brain age estimation:premise,promise,and problems

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Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron Ji Hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

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Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia

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Neuropsychiatric Disease and Treatment 2025年 21卷 943-954页

作者： Natsuyama, Tomoya Chibaatar, Enkhmurun Shibata, Yuko Okamoto, Naomichi Victorino, John Noel Cruz Ikenouchi, Atsuko Shibata, Tomohiro Yoshimura, Reiji Department of Psychiatry University of Occupational and Environmental Health Fukuoka Kitakyushu 807-8555 Japan Department of Life Science and System Engineering Graduate School of Life Science and Systems Engineering Kyushu Institute of Technology Fukuoka Kitakyushu 808-0135 Japan

Purpose: This study explored the use of advanced computational techniques in vocal analysis to improve the assessment of psychiatric symptoms and cognitive functions in schizophrenia. We hypothesized that digital signal processing techniques, such as mel spectrogram and mel-frequency cepstral coefficients (MFCC), could be used for objective evaluation of psychiatric symptoms and cognitive functions based on the analysis of alterations in the vocal characteristics. Patients and Methods: Voice samples from 14 participants diagnosed with schizophrenia (92.9% female) were collected using a microphone array, and vocal features were extracted from the samples using mel spectrogram and MFCC techniques. Psychiatric symptoms and cognitive functions were assessed using the Positive and Negative Syndrome Scale (PANSS) and the computer-based tool Cognitrax. Results: We found significant negative correlations between specific vocal features (mel spectrogram and MFCC) and cognitive functions, particularly working memory (β = −0.645, p = 0.023) and sustained attention (β = −0.626, p = 0.029). No direct correlations were found between vocal features and psychiatric symptoms, as measured by PANSS scores. However, the correlations between cognitive functions and PANSS total scores were significant (β = −0.604, p = 0.037), suggesting that cognitive functions may mediate the relationship between psychiatric symptoms and vocal characteristics. Conclusion: This study underscores the potential of vocal analysis as a non-invasive tool for assessing cognitive impairment in schizophrenia. Future research should focus on expanding the sample size and including diverse populations to enhance the generalizability of these findings. © 2025 Natsuyama et al.

关键词： acoustics cognition computer-assisted signal processing diagnostic and statistical manual of mental disorders positive and negative syndrome scale schizophrenic psychology

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Association of maternal multi-metal exposure and dyslipidemia: a study of air pollution on pregnancy outcomes

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BMC Pregnancy and Childbirth 2025年第1期25卷 1-9页

作者： Go, Yoon-Young Hur, Young Min You, Young-Ah Park, Sunwha Lee, Gain Chae, Rin Kim, Soo-Min Kim, Young Ju Department of Obstetrics and Gynecology College of Medicine and Ewha Medical Institute Ewha Womans University 1071 Anyangcheon-Ro Yangcheon-Gu Seoul 07985 South Korea Graduate Program in System Health Science and Engineering Ewha Womans University Seoul 07985 South Korea Graduate Program in Division of Artificial Intelligence and Software/Artificial Intelligence Convergence Ewha Womans University Seoul 07985 South Korea

Background: Exposure to air pollutants, including heavy metals, is a major environmental concern of public health and these environmental toxicants have been associated with pregnancy complications. Objectives: An air pollution on pregnancy outcome (APPO) study was performed to investigate the adverse effects of fine particulate matter (PM_2.5) exposure on pregnancy outcomes. This study examined the association between maternal urinary metal mixtures and pregnancy complications, including dyslipidemia and preterm birth (PTB). Methods: The concentrations of 16 metals were measured in 60 urine samples collected during the second trimester pregnancy. Logistic regression and Bayesian kernel machine regression (BKMR) models were used to analyze the single and overall effects of metal exposure on pregnancy complications, respectively. Results: Logistic regression analysis showed a significant difference in urinary Ni and Zn concentrations between those exposed to high and low concentrations of fine particulate matter with an aerodynamic diameter of less than 2.5 µm (PM_2.5) and those not exposed. Four metals (Ni, Sc, Mo, and Cs) were positively associated with total cholesterol (TC) levels, but not with triglyceride (TG) levels and PTB. The BKMR model showed that the overall mixture of 16 metals was positively correlated with high TC and TG levels during the third trimester of pregnancy, and the individual effects of Mo and Pb were the most significant. However, we were only able to identify a trend between maternal exposure to metal mixtures and PTB. Conclusions: BKMR analyses showed a positive association between exposure to multi-metal mixtures and higher maternal TC and TG levels, a factor that contributes to PTB. Therefore, this also suggests that multi-metal exposure during pregnancy may be a potential risk factor for PTB. © The Author(s) 2025.

关键词： Heavy metals Overall effect Pregnancy outcomes Total cholesterol Triglyceride

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Basal and Edge Plane Activity of Two-Dimensional Dirac Semimetal Nite2 for Hydrogen Evolution Reaction

SSRN

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SSRN 2025年

作者： Cho, Suyeon Jeong, Seung Weon Kim, Jeong Hyo Lee, Seungyeon Yang, Heejun Lee, Sangheon Division of Chemical Engineering and Materials Science Graduate Program in System Health Science and Engineering Ewha Womans University Seoul03760 Korea Republic of Daejeon34141 Korea Republic of

. Nickel ditelluride (NiTe2), one of group-10 transition metal dichalcogenides, has shown intriguing surface states originating from its topological semi-metallicity. Here, we demonstrate abnormal catalytic activities at the NiTe2 surface for hydrogen evolution reaction (HER). We investigate the differences in catalytic activities at the basal and edge planes of NiTe2 using a micro-sized electrochemical reactor. The basal plane is found to be more active than the edge plane, resulting in a current density at the basal plane of NiTe2 exceeding 800 mA/cm2 with a small overpotential of -0.162 V. We conduct ab initio calculations to estimate the intrinsic catalytic activities of HER on the basal and edge planes of NiTe2. Interestingly, our calculation results suggest that the active sites at the edge plane are electrochemically more active than those at the basal plane. The discrepancy between the experimental measurements and theoretical predictions for the crystal-orientation-dependent HER activity highlights that the specialty of a topological semimetal plays a vital role in determining the HER rate for NiTe2 nanoparticle catalysts © 2025, The Authors. All rights reserved.

关键词： Hydrogen evolution reaction

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Optimizing waste pre-collection model in Indonesian communities: comparing drop-off and door-to-door models through social cost–benefit analysis

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Journal of Material Cycles and Waste Management 2025年 1-17页

作者： Miftahadi, Machmuddin Fitra Hibino, Kohei Rachman, Indriyani Matsumoto, Toru Graduate Program in Environmental System Graduate School of Environmental Engineering The University of Kitakyushu Kitakyushu808-0135 Japan Kitakyushu Urban Centre Institute for Global Environmental Strategies Kitakyushu805-0062 Japan Department of Natural Science Education School of Postgraduate Studies Universitas Pakuan Kota Bogor16143 Indonesia Research Center for Urban Energy Management Institute of Environmental Science and Technology The University of Kitakyushu Kitakyushu808-0135 Japan

Indonesia lacks an established waste pre-collection system resulting 90% waste ending up in open-dumping site. This study identifies a 35-m radius per drop-off points as the most optimal model. The City of South Tangerang, on 21 residential areas with a population of 63,157, being examine. Utilizing ArcGIS Pro and Python scripting, 12 scenarios were developed, model drop-off radii of 15–45 m and household limits of 4–32 per drop-off point, including combined models. Spatial clustering KD-Tree algorithm and Proximity-based Routing were employed to determine collection placements and walking distances. Heatmap and ANOVA tests evaluated conformity with residential characteristics. Model then organized into eight frequency schemes, utilizing motorcart and handcart systems with 4-day and 2-day pickup schedules for waste bank and in-house compost programs. This optimized model reduces collection time by up to 81% and costs by 50% compared to traditional door-to-door systems, achieving cost reductions of $30–$38 USD per ton and lowering CO₂ emissions. The discussion covers opportunity costs and occupational risk. This approach supports Indonesia’s waste reduction targets and offers policy alignment for urban waste management. © The Author(s), under exclusive licence to Springer Nature Japan KK, part of Springer Nature 2025.

关键词： Python

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Damage-Free Neutral Beam Etching for Gate Recess in E-Mode AlGaN/GaN HEMTs

IEEE Electron Device Letters

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IEEE Electron Device Letters 2025年第5期46卷 705-708页

作者： Chen, Yi-Ho Chu, Fu-Chuan Aslam, Muhammad Lee, Yao-Jen Li, Yiming Samukawa, Seiji National Yang Ming Chiao Tung University Parallel and Scientific Computing Laboratory Graduate Degree Program of College of Electrical and Computer Engineering Hsinchu300093 Taiwan National Chung-Shan Institute of Science and Technology Solid State Devices Section Electronic System Research Division Taoyuan325 Taiwan National Yang Ming Chiao Tung University Parallel and Scientific Computing Laboratory Electrical Engineering and Computer Science International Graduate Program Hsinchu300093 Taiwan Institute of Pioneer Semiconductor Innovation National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Institute of Pioneer Semiconductor Innovation Institute of Artificial Intelligence Innovation National Yang Ming Chiao Tung University Parallel and Scientific Computing Laboratory Institute of Biomedical Engineering Department of Electronics and Electrical Engineering Institute of Communications Engineering Hsinchu300093 Taiwan National Yang Ming Chiao Tung University Institute of Communications Engineering Department of Electronics and Electrical Engineering Hsinchu300093 Taiwan

Recess gate etching is a critical technique for achieving enhancement-mode (E-mode) AlGaN/GaN high-electron mobility transistors (HEMTs) because the interface is susceptible to the etching damage. This study fabricates recess gates using the neutral beam etching (NBE) technique. By adjusting the aperture thickness in the NBE apparatus, we simulate both NB-mode and plasma-mode etching. The electrical characteristics of E-mode HEMTs fabricated using these two modes are analyzed and compared through DC, noise, and pulsed IV measurements. The results demonstrate that NB-recessed HEMTs exhibit superior performance. © 1980-2012 IEEE.

关键词： Aluminum gallium nitride

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Testing Facility Location with Constrained Queue Time Problem: A Case Study in Florida, USA 24

Testing Facility Location with Constrained Queue Time Proble...

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Proceedings of the Winter Simulation Conference

作者： Almir Antonio Monteiro Junior Rafael Schneider Vanessa de Almeida Guimarães Pedro Henrique González System Engineering and Computer Science Program Federal University of Rio de Janeiro BRAZIL COPPEAD Graduate School of Business Federal University of Rio de Janeiro BRAZIL

ISBN: (纸本)9798331534202

This study addresses the Testing Facility Location with Constrained Queue Time Problem. This optimization problem focuses on determining the best places to deploy testing sites and their available testers for infectious diseases, while constraining the maximum time in the queue with a given probability. An integer programming model is introduced and applied to the three biggest counties, in terms of population, of Florida, United States. Moreover, the Monte Carlo method is used to evaluate the model's output, aiming to check if the queueing time constraint is being satisfied. Through the experiments, a testing facility deployment plan can be determined for each county and further validated by the simulation. The results show that the solutions returned by the model behaved successfully when submitted to the Monte Carlo method, not exceeding the time in the queue in more than the predefined probability.

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The association between urinary tract infections and diet: a literature review

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Discover Medicine 2025年第1期2卷 1-17页

作者： Çelik, Haluk Kozan, Esra Caf, Balım Bengisu Çebi, Gizem Koç, Murat Vivosens Inc. San Francisco USA Program of Stem Cell and Tissue Engineering Institute of Graduate Education Istinye University Istanbul Türkiye Department of Health Informatics University of Health Science Hamidiye Institute of Health Sciences Istanbul Türkiye

Urinary tract infections (UTIs) are a significant global health concern, affecting millions worldwide, with particular prevalence among specific vulnerable populations. Women of sexually active age, post-menopausal women, pregnant women, individuals with diabetes, catheterized patients, childs and older indivisuals face heightened risk due to various physiological, hormonal, and anatomical factors. While anatomical abnormalities and behavioral factors contribute to UTI susceptibility, the growing challenge of antibiotic resistance has necessitated exploration of alternative treatment approaches. Non-antibiotic interventions, including probiotics, cranberry products, and natural remedies, are gaining attention for their potential role in UTI prevention and management. Recent studies suggest the efficacy of probiotics and plant extracts in promoting urinary tract health and preventing bacterial colonization. Additionally, research highlights the importance of dietary factors, such as vitamin D and probiotic intake, in reducing UTI susceptibility. This review examines the emerging shift toward non-drug strategies, offering a more comprehensive approach to UTI management while addressing the pressing concern of antibiotic resistance.

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Kimchi-derived probiotic intervention improve metabolic health in a sex-specific manner in rat offspring affected by maternal diet and postnatal nutrition

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Journal of Functional Foods 2025年 129卷

作者： You, Young-Ah Kim, Soo Min Lee, Kyeongha Hwang, Subin In Lee, Ga Park, Sunwha Hur, Young Min Go, Yoon-Young Kim, Young Ju Department of Obstetrics and Gynecology College of Medicine and Ewha Medical Institute Ewha Womans University Seoul 07985 South Korea Graduate program in system health science and engineering Ewha Womans University Seoul South Korea

Inadequate maternal nutrition can predispose offspring to obesity and chronic metabolic diseases. This study used a rat model to investigate the impact of maternal high-fat diet-induced metabolic disturbances and the therapeutic potential of WIKIM51, a Weissella confusa strain derived from kimchi. Offspring of high-fat diet-fed dams were assigned to either a normal diet (HF) or continued high-fat diet (OB). At 10 weeks of age, rat offspring received WIKIM51 supplementation for 6 weeks. Metabolic outcomes were assessed at 16 weeks, and two-way ANOVA was used to evaluate the effects of diet and probiotic treatment. Male offspring in the HF and OB groups showed increased body and liver weight, fat accumulation, and elevated blood metabolic markers, along with increased hepatic triglyceride levels and lipogenesis marker expression. WIKIM51 supplementation significantly improved these parameters in males, but not in females. These findings suggest that kimchi-derived probiotics may have sex-specific effects on transgenerational metabolic programming. © 2025

关键词： Fetal programming Lipid metabolism Maternal obesity Oxidative stress Weissella confusa WIKIM51

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