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Development of a shoe-type device for collecting gait information

World Congress on Medical Physics and Biomedical engineering: Neuroengineering, Neural systems, Rehabilitation and Prosthetics

作者： Sugimura, Yukinobu Wada, Futoshi Makino, Kenichiro Oda, Taishi Hachisuka, Kenji Ienaga, Takafumi Yang, Zhimei Kimuro, Yoshihiko Otawa, Takenori Yukitake, Naoto Koriyama, Futoshi Tsuji, Takuro Wada, Chikamune Graduate School of Life Science and Systems Engineering Kyushu Institute of Technology Kitakyushu Japan Dept. of Rehabillitation Medicine School of Medicine University of Occupational and Environmental Health Kitakyushu Japan Institutes of System Information Technologies and Nanotechnologies Fukuoka Japan Logical Product Corporation Fukuoka Japan

ISBN: (纸本)9783642038884

We are developing a measurement device by means of which gait information can be obtained that cannot be obtained by existent devices. We are also evaluating the effectiveness of the device in rehabilitation programs. The final goal of our work is to realize a space where patients can execute their rehabilitation routines at any time. In this paper, we report the outline of our novel measurement device. That is to say, we describe our real-time measurement technique for measuring the position and angle of the feet to obtain the gait information, as well as our method of presenting the gait in formation. © 2009 Springer-Verlag.

关键词： Wearable technology

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A novel single-wire digital handshake of communication speed for universal connector

A novel single-wire digital handshake of communication speed...

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International Conference on Electrical, Control and Instrumentation engineering (ICECIE)

作者： Yoshinobu Tanno Takafumi Hayashi Graduate School of Science and Technology Niigata University Niigata Japan Smart Intelligent System Program Faculty of Engineering Niigata University Niigata Japan

ISBN: (纸本)9781728139401

Industrial development promotes the production of various electronics for contributing to our life. On the other hand, various electronics occur the compatibility trouble about the communication standard. Especially, the compatibility of physical connection standards such as USB or Ethernet is required without the converter of the connector. One way to solve the compatibility of physical connection is the universal connector that enables optimal communication according to the connection partner. The universal connector can be realized by single-wire handshake of pin assignment which automatically negotiates the voltage signal or the role of the pin. After the connection between the pin, all connected pin conducts the single-wire handshake for determining the pin assignment. The single-wire pin assignment handshake consists of the physical half-duplex communication that conducts transmission and reception on one connection line. The physical half-duplex communication requires the single-wire handshake of the communication speed because the multi-pin cannot use for the communication. In addition, the communication speed cannot determine in advance because the connection partner is assumed various for the compatibility. In this paper, we propose the single-wire handshake which automatically adjusts the communication speeds for the universal connector. Moreover, the feasibility of our method is evaluated by the analysis result of the voltage signal between electronics.

关键词： handshake wired communication universal connector shaking hands pin assignment Communication Research Connector Device Component PIN Electronics Wireless networks Connections Communication standards

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Novel diamond shuttle to deliver flexible neural probe with reduced tissue compression

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Microsystems & Nanoengineering 2020年第1期6卷 903-915页

作者： Kyounghwan Na Zachariah J.Sperry Jiaao Lu Mihaly Voroslakos Saman S.Parizi Tim M.Bruns Euisik Yoon John P.Seymour Electrical Engineering&Computer Science Department University of MichiganAnn ArborMI 48105USA Biomedical Engineering Department University of MichiganAnn ArborMI 48105USA Biointerfaces Institute University of MichiganAnn ArborMI 48105USA The Neuroscience Institute New York UniversityNew YorkNY 10016USA Center for Nanomedicine Institute for Basic Science(IBS)Seoul 03722Korea Graduate Program of Nano Biomedical Engineering(Nano BME) Yonsei-IBS InstituteYonsei UniversitySeoul 03722Korea Vivian L Smith Department of Neurosurgery University of Texas Health Science CenterHoustonTX 77030USA Department of Electrical and Computer Engineering Rice UniversityHoustonTX 77005USA

The ability to deliver flexible biosensors through the toughest membranes of the central and peripheral nervous system is an important challenge in neuroscience and neural *** devices implanted through dura mater and thick epineurium would ideally create minimal compression and acute damage as they reach the neurons of *** demonstrate that a three-dimensional diamond shuttle can be easily made with a vertical support to deliver ultra-compliant polymer microelectrodes(4.5-µm thick)through dura mater and thick *** diamond shuttle has 54%less cross-sectional area than an equivalently stiff silicon shuttle,which we simulated will result in a 37%reduction in blood vessel *** also discovered that higher frequency oscillation of the shuttle(200Hz)significantly reduced tissue compression regardless of the insertion speed,while slow speeds also independently reduced tissue *** and recording performance are demonstrated in rat and feline models,but the large design space of these tools are suitable for research in a variety of animal models and nervous system targets.

关键词： sectional neural thick

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Skin Dose Impact from Vacuum Immobilization Device and Carbon Fiber Couch in Intensity Modulated Radiation Therapy for Prostate Cancer

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Medical Dosimetry 2009年第3期34卷 228-232页

作者： Lee, Kuo-Wei Wu, Jian-Kuen Jeng, Shiu-Chen Hsueh Liu, Yen-Wan Cheng, Jason Chia-Hsien Department of Oncology National Taiwan University Hospital Taipei Taiwan Graduate Institute of Clinical Medicine National Taiwan University College of Medicine Taipei Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu Taiwan Division of Health Physics Institute of Nuclear Energy Research Taoyuan Taiwan

To investigate the unexpected skin dose increase from intensity-modulated radiation therapy (IMRT) on vacuum cushions and carbon-fiber couches and then to modify the dosimetric plan accordingly. Eleven prostate cancer patients undergoing IMRT were treated in prone position with a vacuum cushion. Two under-couch beams scattered the radiation from the vacuum cushion and carbon-fiber couch. The IMRT plans with both devices contoured were compared with the plans not contouring them. The skin doses were measured using thermoluminescent dosimeters (TLDs) placed on the inguinal regions in a single IMRT fraction. Tissue equivalent thickness was transformed for both devices with the relative densities. The TLD-measured skin doses (59.5 ± 9.5 cGy and 55.6 ± 5.9 cGy at left and right inguinal regions, respectively) were significantly higher than the calculated doses (28.7 ± 4.7 cGy;p = 2.2 × 10^-5 and 26.2 ± 4.3 cGy;p = 1.5 × 10^-5) not contouring the vacuum cushion and carbon-fiber couch. The calculated skin doses with both devices contoured (59.1 ± 8.8 cGy and 55.5 ± 5.7 cGy) were similar to the TLD-measured doses. In addition, the calculated skin doses using the vacuum cushion and a converted thickness of the simulator couch were no different from the TLD-measured doses. The recalculated doses of rectum and bladder did not change significantly. The dose that covered 95% of target volume was less than the prescribed dose in 4 of 11 patients, and this problem was solved after re-optimization applying the corrected contours. The vacuum cushion and carbon-fiber couch contributed to increased skin doses. The tissue-equivalent-thickness method served as an effective way to correct the dose variations. © 2009 American Association of Medical Dosimetrists.

关键词： Couch Intensity-modulated radiation therapy Prostate cancer Skin Vacuum immobilization device

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Simulation of acoustical noise reduction for magnetic resonance imaging by an active control headphone with piezoelectric plate and earmuff 44

Simulation of acoustical noise reduction for magnetic resona...

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44th International Congress and Exposition on Noise Control engineering, INTER-NOISE 2015

作者： Osada, Ryosuke Muto, Kenji Yagi, Kazuo Chen, Guyoue Shibaura Institute of Technology Graduate School of Engineering and Science 3-7-5 Toyosu Koto-ku Tokyo135-8548 Japan Graduate School of Human Health Sciences Tokyo Metropolitan University 7-2-10 Higashioku Arakawa-ku Tokyo116-8551 Japan Faculty of System Science and Technology Akita Prefectural University 84-4 Ebinokuchi Tsuchiya Yurihonjo Akita015-0055 Japan

Magnetic resonance imaging (MRI) machines are widely used for medical examinations. However, they generate acoustical noise with sound pressure levels exceeding 100 dB. To solve this problem, we propose a headphone that uses active noise control (ANC) by a piezoelectric vibration plate in combination with an earmuff. This paper presents the results of analyzing MRI noise and shows the simulated noise reduction performance for the headphones with an inverse filter for pre-whitening in the simulated MRI room. Because MRI examination rooms are high-magnetic-field environments, all magnetic materials are prohibited. The proposed headphone uses a piezoelectric vibration plate made from a nonmagnetic material. Feedforward control is employed because the MRI noise has a pulse waveform with unstable amplitude. The headphone showed good noise reduction performance in the low-frequency band by ANC and in the high-frequency band by earmuff. The noise level was reduced to 67.9 dB. The headphone provides a more comfortable acoustic environment than the earmuff alone for a subject undergoing an MRI examination. © 2015 by ASME.

关键词： Magnetic resonance imaging

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Generative Chemical Transformer: Neural Machine Learning of Molecular Geometric Structures from Chemical Language via Attention

arXiv

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arXiv 2021年

作者： Kim, Hyunseung Na, Jonggeol Lee, Won Bo School of Chemical and Biological Engineering Seoul National University Gwanak-ro 1 Gwanak-gu Seoul08826 Korea Republic of Department of Chemical Engineering and Materials Science Graduate Program in System Health Science and Engineering Ewha Womans University Seoul03760 Korea Republic of

Discovering new materials better suited to specific purposes is an important issue in improving the quality of human life. Here, a neural network that creates molecules that meet some desired conditions based on a deep understanding of chemical language is proposed (Generative Chemical Transformer, GCT). The attention mechanism in GCT allows a deeper understanding of molecular structures beyond the limitations of chemical language itself which cause semantic discontinuity by paying attention to characters sparsely. It is investigated that the significance of language models for inverse molecular design problems by quantitatively evaluating the quality of the generated molecules. GCT generates highly realistic chemical strings that satisfy both chemical and linguistic grammar rules. Molecules parsed from generated strings simultaneously satisfy the multiple target properties and vary for a single condition set. These advances will contribute to improving the quality of human life by accelerating the process of desired material discovery. Copyright © 2021, The Authors. All rights reserved.

关键词： Molecules

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Anti-malaria drug artesunate protects bronchial epithelium from DNA damage induced by asthma

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中国药理学与毒理学杂志 2015年第S1期29卷 25-26页

作者： TzeKheeCHAN WNFeliciaTAN BevinPENGELWARD WSFredWONG Department of Pharmacology Yong Loo Lin School of Medicine National University Health System Singapore Immunology Program Life Science Institute National University of Singapore Interdisciplinary Research Group in Infectious Diseases Singapore-MIT Alliance for Research and Technology Singapore Department of Biological Engineering Massachusetts Institute of Technology Cambridge MA 02139 USA

OBJECTIVE To investigate the genome protective effects of anti-malaria drug,artesunate in an experimental allergic asthma *** Mice were sensitized on day 0 and 7 and challenged on day 14 with 100μg house dust mite(HDM)via intratracheal ***(30mg·kg-1)was administered intra-peritoneally on day 6,7,8,13,14 and *** were collected on day 1,3 and 5 post last HDM-challenge for analysis of air way inflammation and DNA *** sections were immunofluorescence(IF)-stained for DNA double strand breaks(DSBs)markers,γH2AX and *** of DNA repair proteins Ku70 and Rad51,which are involved in non-homologous end joining(NHEJ)and homologous recombination(HR)DNA DSB repair pathways respectively,were *** quantify cell death in asthmatic lung,TUNEL staining was *** assay,a single cell gel electrophoresis was employed to detect DNA damage induced by HDM in BEAS-2Bhuman bronchial epithelial cell line,in *** Artesunate treatment significantly reduces immune cells infiltration in BAL fluid of asthmatic mice,collected on day 3 and 5 ***,artesuante is able to protect bronchial epithelium from DNA DSBs induced by asthma,as detected by the reduced level of γH2AX and 53BP1 foci formation in the *** genome protective effect is evident even on day 1 post-challenge,when immune cells infiltration remained *** indicates that artesunate confers protection on bronchial epithelium in the presence of ***,artesunate is also able to reduce cell death in asthmatic lung revealed by TUNEL assay and cleaved caspase 3 ***,the levels of DNA repair proteins in artesuante-treated asthmatic mice are unchanged as compared to HDM-only mice,suggesting that artesunate treatment does not augment the level of DNA repair *** human bronchial epithelial BEAS-2 Bcells were exposed to HDMin vitro,we observed an increase in the levels of DNA ***(60μ

关键词： artesunate HDM asthma DNA damage cell death comet

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Light scattering from coupled plasmonic nanospheres on a stretchable substrate for application as a biosensor or mechanical sensor

Light scattering from coupled plasmonic nanospheres on a str...

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2013 3rd International Conference on Advanced Materials and Information Technology Processing (AMITP 2013)

作者： Huai-Yi Xie Mohammad Tariq Yaseen Rakesh Singh Moirangthem Yia-Chung Chang Research Centre for Applied Sciences Academia Sinica Nano Science and Technology Program Taiwan International Graduate ProgramAcademia Sinica Department of Engineering and System Science NTHU Max-Planck-Institut fur Eisenforschung

ISBN: (纸本)9781845648534

The ellipsometric spectra(Ψ and ?) of coupled metallic nanoparticles on a stretchable substrate have been studied via the spherical-harmonics based Green's function *** use Au trimmer nanoparticles and dielectric *** calculated ellipsometric spectra show a plasmonic resonance peak with asymmetric *** a trimmer of metallic nanoparticles on a stretchable substrate,the separation between nanoparticles in the trimmer can be varied by the applied mechanical *** find that both the plasmonic resonance peak position and the signal strength at the resonance frequency are sensitive to the gap distance in the trimmer,which can be controlled by the stretchable *** simulation results indicate that the sensitivity of the plasmonic resonance lineshape to the inter-particle distance allows this coupled nanoparticle system to be used as a biosensor or mechanical *** experimental ellipsometric spectra for closely-spaced metallic nanoparticles on a PDMS substrate are also reported.

关键词： stretchable material optical metrology scattering theory

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Seasonal Variation of the Monthly Efficiencies of Thin Film PV Modules 5

Seasonal Variation of the Monthly Efficiencies of Thin Film ...

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5th International Renewable and Sustainable Energy Conference, IRSEC 2017

作者： Özden, Talat Turan, Raşit Akmoǧlu, Bülent Gültekin Department of Electrical and Electronics Engineering Gümüşhane University Günüşhane29100 Turkey Ankara06800 Turkey Department of Physics Faculty of Arts and Sciences METU Ankara06800 Turkey Earth System Science Program Graduate School of Natural and Applied Sciences METU Ankara06800 Turkey

ISBN: (纸本)9781538628478

Outdoor testing of solar photovoltaic (PV) modules must be carried out at different climates as PV power plants nowadays are installed and continues to be installed in many countries. Present study is outdoor testing results and analyses of 5 thin film modules in Ankara, Turkey. The analyses are carried out using monthly efficiencies of the modules that are derived using the energy yield and input. The average efficiencies of the CIS, CIGS and μc-Si/a-Si thin film modules are. We present the monthly and average efficiencies and discuss their variations with the parameter: input, ambient temperature and relative humidity. We also carried out seasonal analyses using Pearson's correlation coefficient and find out that the efficiencies are differently dependent on the above mentioned parameters. This arose a new open question on differentiation of the strength of the effect of each parameter on the monthly efficiencies. © 2017 IEEE.

关键词： Solar energy

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Origin of nonlinear photocurrents in chiral multifold semimetal CoSi unveiled by terahertz emission spectroscopy

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Physical Review B 2024年第20期110卷 L201118-L201118页

作者： Yao-Jui Chan Syed Mohammed Faizanuddin Raju Kalaivanan Sankar Raman Hsin Lin Uddipta Kar Akhilesh Kr. Singh Wei-Li Lee Ranganayakulu K. Vankayala Institute of Physics Academia Sinica Taipei 11529 Taiwan Taiwan International Graduate Program Academia Sinica Taipei 11529 Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu 300044 Taiwan

Spectroscopic identification of distinct nonlinear photocurrents unveils quantum geometric properties of electron wave functions and the momentum-space topological structures. This is especially interesting, but still puzzling, for chiral topological semimetals with possibilities of hosting giant quantized circular photogalvanic effect. Here we report a comprehensive terahertz (THz) emission spectroscopic analysis of nonlinear photoconductivity of chiral multifold CoSi at 0.26 ∼ 1 eV. We find a large linear shift conductivity (17µA/V2), and confirm a giant injection conductivity (167µA/V2) as a consequence of strongly interfered nonquantized contributions from the vicinity of multifold nodes with opposite chiralities. The bulk injection current excited by the pump field with a complex wave vector is shown to carry both longitudinal and transverse components. Symmetry analyses further unveil weak nonlocal photon drag effect in addition to the photogalvanic effect. This work not only highlights chiral transition-metal monosilicides for midinfrared photovoltaic applications via various nonlinear optical channels, but also consolidates the THz spectroscopy for quantitative photovoltaic research.

关键词： Optical & microwave phenomena Photocurrent Topological materials Weyl semimetal Resistivity measurements Terahertz techniques

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