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arXiv 2017年

作者： Khaleel, Mai Ibrahim Chen, Yu-Da Chien, Ching-Hang Chang, Yia-Chung Research Center for Applied Sciences Academia Sinica Taipei11529 Taiwan Nano Science and Technology Program Taiwan International Graduate Program Academia Sinica and National Tsing Hua University Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu30013 Taiwan

Microscopic Imaging Ellipsometry is an optical technique that uses an objective and sensing procedure to measure the ellipsometric parameters Ψ and Δ in the form of microscopic maps. This technique is well known for being non-invasive and label-free. Therefore it can be used to detect and characterize biological species without any impact. In this work MIE was used to measure the optical response of dried Streptococcus mutans cells on a glass substrate. The ellipsometric Ψ and Δ maps were obtained with Optrel Multiskop system for specular reflection in the visible range (λ= 450nm -750nm). The Ψ and Δ images at 500nm, 600nm, and 700nm were analyzed using three different theoretical models with single-bounce, two-bounce, and multi-bounce light paths to obtain the optical constants and height distribution. The obtained images of the optical constants show different aspects when comparing the single-bounce analysis with the two-bounce or multi-bounce analysis in detecting S. mutans samples. Furthermore, the height distributions estimated by two-bounce and multi-bounce analysis of S. mutans samples were in agreement with the thickness values measured by AFM, which implies that the two-bounce and multi-bounce analysis can provide information complementary to that obtained by single-bounce light path. Copyright © 2017, The Authors. All rights reserved.

关键词： Ellipsometry

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Transcript expression-aware annotation improves rare variant interpretation (vol 581, pg 452, 2020)

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NATURE 2021年第7846期590卷 E54-E54页

作者： Cummings, Beryl B. Karczewski, Konrad J. Kosmicki, Jack A. Seaby, Eleanor G. Watts, Nicholas A. Singer-Berk, Moriel Mudge, Jonathan M. Karjalainen, Juha Satterstrom, F. Kyle O'Donnell-Luria, Anne H. Poterba, Timothy Seed, Cotton Solomonson, Matthew Alfoldi, Jessica Daly, Mark J. MacArthur, Daniel G. Program in Medical and Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA Analytical and Translational Genetics Unit Massachusetts General Hospital Boston MA USA Program in Biological and Biomedical Sciences Harvard Medical School Boston MA USA Program in Bioinformatics and Integrative Genomics Harvard Medical School Boston MA USA Genomic Informatics Group University Hospital Southampton Southampton UK Stanley Center for Psychiatric Research Broad Institute of MIT and Harvard Cambridge MA USA Division of Genetics and Genomics Boston Children’s Hospital Boston MA USA Department of Pediatrics Harvard Medical School Boston MA USA European Molecular Biology Laboratory European Bioinformatics Institute Wellcome Genome Campus Hinxton Cambridge UK Center for Genomic Medicine Massachusetts General Hospital Boston MA USA Broad Genomics Broad Institute of MIT and Harvard Cambridge MA USA National Heart & Lung Institute and MRC London Institute of Medical Sciences Imperial College London London UK Cardiovascular Research Centre Royal Brompton & Harefield Hospitals NHS Trust London UK Cardiac Arrhythmia Service and Cardiovascular Research Center Massachusetts General Hospital Boston MA USA Estonian Genome Center Institute of Genomics University of Tartu Tartu Estonia Department of Medicine Harvard Medical School Boston MA USA Cardiac Arrhythmia Service Massachusetts General Hospital Boston MA USA Division of General Internal Medicine Massachusetts General Hospital Boston MA USA Institute for Molecular Medicine FIMM University of Helsinki Helsinki Finland Department of Public Health Faculty of Medicine University of Helsinki Helsinki Finland Department of Genetics Harvard Medical School Boston MA USA Data Sciences Platform Broad Institute of MIT and Harvard Cambridge MA USA Genomics Platform Broad Institute of MIT and Harvard Cambridge MA USA Wellcome Sanger Institute Hinxton Cambridgeshire UK Unidad de Investigaci

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Efficient Construction Method for Phase Diagrams Using Uncertainty Sampling

arXiv

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arXiv 2018年

作者： Terayama, Kei Tamura, Ryo Nose, Yoshitaro Hiramatsu, Hidenori Hosono, Hideo Okuno, Yasushi Tsuda, Koji RIKEN Center for Advanced Intelligence Project Tokyo103-0027 Japan Medical Sciences Innovation Hub Program RIKEN Cluster for Science Technology and Innovation Hub Kanagawa230-0045 Japan Graduate school of Medicine Kyoto University Kyoto606-8507 Japan National Institute for Materials Science Ibaraki305-0044 Japan Research and Services Division of Materials Data and Integrated System National Institute for Materials Science Ibaraki305-0047 Japan Graduate school of Frontier Sciences University of Tokyo Chiba277-8568 Japan Department of Materials Science and Engineering Kyoto University Kyoto606-8501 Japan Laboratory for Materials and Structures Institute of Innovative Research Tokyo Institute of Technology Yokohama226-8503 Japan Materials Research Center for Element Strategy Tokyo Institute of Technology Yokohama226-8503 Japan

We develop a method to efficiently construct phase diagrams using machine learning. Uncertainty sampling (US) in active learning is utilized to intensively sample around phase boundaries. Here, we demonstrate constructions of three known experimental phase diagrams by the US approach. Compared with random sampling, the US approach decreases the number of sampling points to about 20%. In particular, the reduction rate is pronounced in more complicated phase diagrams. Furthermore, we show that using the US approach, undetected new phase can be rapidly found, and smaller number of initial sampling points are sufficient. Thus, we conclude that the US approach is useful to construct complicated phase diagrams from scratch and will be an essential tool in materials science. Copyright © 2018, The Authors. All rights reserved.

关键词： Graphic methods

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Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort

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Movement disorders : official journal of the Movement Disorder Society 2023年第2期38卷 286-303页

作者： Eva-Juliane Vollstedt Susen Schaake Katja Lohmann Shalini Padmanabhan Alexis Brice Suzanne Lesage Christelle Tesson Marie Vidailhet Isabel Wurster Faycel Hentati Anat Mirelman Nir Giladi Karen Marder Cheryl Waters Stanley Fahn Meike Kasten Norbert Brüggemann Max Borsche Tatiana Foroud Eduardo Tolosa Alicia Garrido Grazia Annesi Monica Gagliardi Maria Bozi Leonidas Stefanis Joaquim J Ferreira Leonor Correia Guedes Micol Avenali Simona Petrucci Lorraine Clark Ekaterina Y Fedotova Natalya Y Abramycheva Victoria Alvarez Manuel Menéndez-González Silvia Jesús Maestre Pilar Gómez-Garre Pablo Mir Andrea Carmine Belin Caroline Ran Chin-Hsien Lin Ming-Che Kuo David Crosiers Zbigniew K Wszolek Owen A Ross Joseph Jankovic Kenya Nishioka Manabu Funayama Jordi Clarimon Caroline H Williams-Gray Marta Camacho Mario Cornejo-Olivas Luis Torres-Ramirez Yih-Ru Wu Guey-Jen Lee-Chen Ana Morgadinho Teeratorn Pulkes Pichet Termsarasab Daniela Berg Gregor Kuhlenbäumer Andrea A Kühn Friederike Borngräber Giuseppe de Michele Anna De Rosa Alexander Zimprich Andreas Puschmann George D Mellick Jolanta Dorszewska Jonathan Carr Rosangela Ferese Stefano Gambardella Bruce Chase Katerina Markopoulou Wataru Satake Tatsushi Toda Malco Rossi Marcelo Merello Timothy Lynch Diana A Olszewska Shen-Yang Lim Azlina Ahmad-Annuar Ai Huey Tan Bashayer Al-Mubarak Hasmet Hanagasi Dariusz Koziorowski Sibel Ertan Gençer Genç Patricia de Carvalho Aguiar Melinda Barkhuizen Marcia M G Pimentel Rachel Saunders-Pullman Bart van de Warrenburg Susan Bressman Mathias Toft Silke Appel-Cresswell Anthony E Lang Matej Skorvanek Agnita J W Boon Rejko Krüger Esther M Sammler Vitor Tumas Bao-Rong Zhang Gaetan Garraux Sun Ju Chung Yun Joong Kim Juliane Winkelmann Carolyn M Sue Eng-King Tan Joana Damásio Péter Klivényi Vladimir S Kostic David Arkadir Mika Martikainen Vanderci Borges Jens Michael Hertz Laura Brighina Mariana Spitz Oksana Suchowersky Olaf Riess Parimal Das Brit Mollenhauer Emilia M Gatto Maria Skaalum Petersen Nobutaka Hattori Ruey-Meei Wu Sergey N Illarioshkin Enz Institute of Neurogenetics University of Lübeck Lübeck Germany. Research Programs The Michael J. Fox Foundation for Parkinson's Research New York New York USA. Department of Neurology Sorbonne University Paris Brain Institute - ICM Inserm CNRS Assistance Publique Hôpitaux de Paris Pitié-Salpêtrière Hospital Paris France. Sorbonne University Paris Brain Institute - ICM Inserm CNRS Paris France. Department of Neurodegenerative Diseases University of Tuebingen Tuebingen Baden Wuerttemberg Germany Hertie Institute for Clinical Brain Research and German Centre for Neurodegenerative Diseases Tuebingen Germany. Mongi Ben Hmida National Institute of Neurology Tunis Tunisia. Laboratory of Early Markers of Neurodegeneration Neurological Institute Tel-Aviv Medical Center Tel-Aviv Israel Sackler School of Medicine Tel-Aviv University Tel-Aviv Israel Sagol School of Neuroscience Tel-Aviv University Tel-Aviv Israel. Neurological Institute Tel-Aviv Medical Center Tel-Aviv Israel Sackler School of Medicine Sagol School of Neuroscience Tel-Aviv University Tel-Aviv Israel. Department of Neurology Taub Institute for Alzheimer's Disease and the Aging Brain Columbia University New York New York USA. Department of Neurology Columbia University New York New York USA. Department of Psychiatry and Psychotherapy and Institute of Neurogenetics University of Lübeck Lübeck Germany. Department of Neurology and Institute of Neurogenetics University of Lübeck Lübeck Germany. Department of Medical and Molecular Genetics Indiana University School of Medicine Indianapolis Indiana USA. Parkinson Disease and Movement Disorders Unit Neurology Service Hospital Clínic de Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) University of Barcelona (UB) Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED:CB06/05/0018-ISCIII) Barcelona Spain. Institute of Biomedical Research and Innovation National Research Council Cosenza

BACKGROUND:As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is limited. OBJECTIVE:The objectives are to (1) establish an international cohort of affected and unaffected individuals with PD-linked variants; (2) provide harmonized and quality-controlled clinical characterization data for each included individual; and (3) further promote collaboration of researchers in the field of monogenic PD. METHODS:We conducted a worldwide, systematic online survey to collect individual-level data on individuals with PD-linked variants in SNCA, LRRK2, VPS35, PRKN, PINK1, DJ-1, as well as selected pathogenic and risk variants in GBA and corresponding demographic, clinical, and genetic data. All registered cases underwent thorough quality checks, and pathogenicity scoring of the variants and genotype-phenotype relationships were analyzed. RESULTS:We collected 3888 variant carriers for our analyses, reported by 92 centers (42 countries) worldwide. Of the included individuals, 3185 had a diagnosis of PD (ie, 1306 LRRK2, 115 SNCA, 23 VPS35, 429 PRKN, 75 PINK1, 13 DJ-1, and 1224 GBA) and 703 were unaffected (ie, 328 LRRK2, 32 SNCA, 3 VPS35, 1 PRKN, 1 PINK1, and 338 GBA). In total, we identified 269 different pathogenic variants; 1322 individuals in our cohort (34%) were indicated as not previously published. CONCLUSIONS:Within the MJFF Global Genetic PD Study Group, we (1) established the largest international cohort of affected and unaffected individuals carrying PD-linked variants; (2) provide harmonized and quality-controlled clinical and genetic data for each included individual; (3) promote collaboration in the field of genetic PD with a view toward clini

关键词： Parkinson's disease monogenic PD

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Cell migration guided by a groove with branches

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Journal of Biomechanical science and engineering 2017年第1期12卷 16-00613-16-00613页

作者： Miyoshi, Hiromi Nishimura, Miki Yamagata, Yutaka Liu, Hao Watanabe, Yasuyoshi Sugawara, Michiko Pathophysiological and Health Science Team RIKEN Center for Life Science Technologies 6-7-3 Minatojima-minamimachi Chuo Kobe Hyogo650-0047 Japan Health Metrics Development Team RIKEN Compass to Healthy Life Research Complex Program 6-7-1 Minatojima-minamimachi Chuo Kobe Hyogo650-0047 Japan PRIME AMED 6-7-3 Minatojima-minamimachi Chuo Kobe Hyogo650-0047 Japan Graduate School of Engineering Chiba University Chiba 1-33 Yayoicho Inage Chiba263-8522 Japan Ultrahigh Precision Optics Technology Team RIKEN Center for Advanced Photonics 2-1 Hirosawa Wako Saitama Japan

Cell migration is an important process both in physiological and pathological conditions. Migrating cells in vivo respond to various extracellular environmental factors and change their migratory behavior. Thus, it is important to take into account extracellular environmental factors in studies on cell migration. This study specifically focused on fibroblast migration in a three-dimensional microenvironment. We fabricated a polydimethylsiloxane cell culture substrate with intersecting grooves as a model to mimic a feature of the complex porous microenvironment experienced by fibroblasts in vivo. The sizes of the grooves allowed fibroblasts to penetrate into the grooves. The effects of branched grooved structures on cell migration, and on cellular organization of the actin filaments and phosphorylated myosin light chain, were analyzed. Fibroblasts migrated along intersecting lattice grooves that were 5 μm wide, 13 μm deep, and spaced 10 μm apart. Analysis of the cellular distribution of actin filaments and phosphorylated myosin light chain demonstrated two effects of the intersecting grooved structure on actin cytoskeletal organization in the fibroblast. One was the enhancement of filopodia protrusions into the branched groove at the junction, and the other was the formation of stress fibers to cross the opening of the junction. These results suggest that the filopodia protrusions are guided by the groove and are followed by the cytoplasmic protrusion, then the rear of the cell retracts due to stress fiber contraction, leading to fibroblast guided migration in the branched intersecting groove. © 2017 The Japan Society of Mechanical Engineers.

关键词： Fibroblasts

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Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

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Genomics 2020年第2期112卷 1223-1232页

作者： Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA. Electronic address: jason.wong@nih.gov. Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA. Institute of Population Health Sciences National Health Research Institutes Zhunan Taiwan. Division of Genome Biology National Cancer Center Research Institute Tokyo Japan. Division of Cancer Epidemiology and Prevention Aichi Cancer Center Research Institute Nagoya Japan Department of Cancer Epidemiology Nagoya University Graduate School of Medicine Nagoya Japan. Department of Pathology Queen Mary Hospital The University of Hong Kong Hong Kong. Department of Preventive Medicine Seoul National University College of Medicine Seoul Republic of Korea. Ministry of Education Key Laboratory of Contemporary Anthropology School of Life Sciences Fudan University Shanghai China State Key Laboratory of Genetic Engineering School of Life Sciences Fudan University Shanghai China. Saw Swee Hock School of Public Health National University of Singapore Singapore. Cancer Genomics Research Laboratory Leidos Biomedical Research Inc Gaithersburg MD USA Department of Computational Biology St. Jude Children's Research Hospital Memphis TN USA. Division of Cancer Epidemiology and Genetics National Cancer Institute Bethesda MD USA Department of Statistics Sookmyung Women's University Seoul Republic of Korea. Department of Preventive Medicine Chonnam National University Medical School Gwangju Republic of Korea. National Institute of Cancer Research National Health Research Institutes Zhunan Taiwan. Bloomberg School of Public Health Johns Hopkins University Baltimore MD USA. Department of Etiology & Carcinogenesis and State Key Laboratory of Molecular Oncology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China. Division of Thoracic Surgery Kinki University School of Medicine Sayama Japan. Division of

We investigated whether genetic susceptibility to tuberculosis (TB) influences lung adenocarcinoma development among never-smokers using TB genome-wide association study (GWAS) results within the Female Lung Cancer Consortium in Asia. Pathway analysis with the adaptive rank truncated product method was used to assess the association between a TB-related gene-set and lung adenocarcinoma using GWAS data from 5512 lung adenocarcinoma cases and 6277 controls. The gene-set consisted of 31 genes containing known/suggestive associations with genetic variants from previous TB-GWAS. Subsequently, we followed-up with Mendelian Randomization to evaluate the association between TB and lung adenocarcinoma using three genome-wide significant variants from previous TB-GWAS in East Asians. The TB-related gene-set was associated with lung adenocarcinoma (p = 0.016). Additionally, the Mendelian Randomization showed an association between TB and lung adenocarcinoma (OR = 1.31, 95% CI: 1.03, 1.66, p = 0.027). Our findings support TB as a causal risk factor for lung cancer development among never-smoking Asian women.

关键词： Lung adenocarcinoma Lung cancer Mendelian randomization Pathway analysis Tuberculosis

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Photodynamic Therapy: A Flexi‐PEGDA Upconversion Implant for Wireless Brain Photodynamic Therapy (Adv. Mater. 29/2020)

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Advanced Materials 2020年第29期32卷

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Effects of Trekking Pole Use on Metabolic Cost in Novice Hikers on Steep Terrains

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Journal of Sports science 2017年第5期5卷 256-264页

作者： Yong Bin Han Ik Jin Kwon Dae Taek Lee Eun Jin Hwang Jong Kwang Kim Eun Hyung Cho Graduate Program of Sports Engineering Convergence Kookmin University Seou102 707 Korea Department of Sports Health and Rehabilitation Kookmin University Seou102707 Korea Graduate School of Sports Natural Science Kookmin University Seou102707 Korea College of Sport Science Sung Kyun Kwan University Gyeonggi-do 16419 Korea

PURPOSE： This study examined whether the use of trekking poles alters metabolic cost in steep hiking by novice hikers and whether the response would be dependent on the grade of the terrain. METHODS： Twelve participants completed two trekking trials （with poles [WP] and without trekking poles [NP]） with round trips comprising three grades： 7.0 ± 0.7°, 12.9 ± 0.7°, and 18.8 ± 1.3°） over a steep mountain at self-paced speeds. During the trials, time spent for trekking （TT）, oxygen consumption （VO2）, heart rate （HR）, ratings of perceived exertion （RPE）, and step frequency （Sf） were measured, and step efficiency （Se） and oxygen pulse （OP） were calculated. RESULTS： TT tended to be longer in the WP than NP for both terrains （P 〈 0.05）. HR, VO2, and RPE were the same for the WP and NP. Sfwas lower in WP going uphill （P 〈 0.05） but was unchanged going downhill. Se in the WP was higher than in the NP for both terrains （P 〈 0.01）. When analyzed by slope, VO2 during uphill at 18.8° was lower in WP （37.2 ± 6.3） than in NP （38.6 ± 7.1 ml .kg-1 .min-1, P 〈 0.05）, but no difference in VO2 was found between WP and NP at the 12.9° and 7.0°. TT during uphill was slower in WP than NP at 12.9°（7.9± 1.1 vs. 7.4 ± 1.0） and 18.8° （5.3 ± 1.3 vs. 4.9± 1.0 min, respectively, P 〈 0.05）. No differences were noticed in HR and OP during uphill at every grade. CONCLUSIONS： Pole use decreased metabolic cost in the novice hikers only in the highest grade but not in the other two lower grades.

关键词： Oxygen uptake heart rate uphill downhill.

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Author Correction: Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state

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Nature communications 2020年第1期11卷 4624页

作者： Takeshi Kawabe Jaeu Yi Akihisa Kawajiri Kerry Hilligan Difeng Fang Naoto Ishii Hidehiro Yamane Jinfang Zhu Dragana Jankovic Kwang Soon Kim Giorgio Trinchieri Alan Sher Immunobiology Section Laboratory of Parasitic Diseases National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH) Bethesda MD 20892 USA. kawabet@med.tohoku.ac.jp. Department of Microbiology and Immunology Tohoku University Graduate School of Medicine Sendai 980-8575 Japan. kawabet@med.tohoku.ac.jp. Academy of Immunology and Microbiology Institute for Basic Science Pohang 37666 Republic of Korea. Department of Integrative Biosciences and Biotechnology Pohang University of Science and Technology Pohang 37673 Republic of Korea. Department of Microbiology and Immunology Tohoku University Graduate School of Medicine Sendai 980-8575 Japan. Immunobiology Section Laboratory of Parasitic Diseases National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH) Bethesda MD 20892 USA. Immune Cell Biology Programme Malaghan Institute of Medical Research Wellington 6012 New Zealand. Molecular and Cellular Immunoregulation Section Laboratory of Immune System Biology NIAID NIH Bethesda MD 20892 USA. Cellular Immunology Section Vaccine Research Center NIAID NIH Bethesda MD 20892 USA. Cancer and Inflammation Program Center for Cancer Research National Cancer Institute NIH Bethesda MD 20892 USA. Immunobiology Section Laboratory of Parasitic Diseases National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health (NIH) Bethesda MD 20892 USA. asher@niaid.nih.gov.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Seasonal Variation of the Monthly Efficiencies of Thin Film PV Modules

Seasonal Variation of the Monthly Efficiencies of Thin Film ...

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International Renewable and Sustainable Energy Conference (IRSEC)

作者： Talat Özden Raşit Turan Bülent Gültekin Akmoğlu Department of Electrical and Electronics Engineering Gümüşhane University Günüşhane Turkey Department of Physics METU Ankara Turkey Earth System Science Program Graduate School of Natural and Applied Sciences Ankara Turkey

Outdoor testing of solar photovoltaic (PV) modules must be carried out at different climates as PV power plants nowadays are installed and continues to be installed in many countries. Present study is outdoor testing results and analyses of 5 thin film modules in Ankara, Turkey. The analyses are carried out using monthly efficiencies of the modules that are derived using the energy yield and input. The average efficiencies of the CIS, CIGS and μc-Si/a-Si thin film modules are. We present the monthly and average efficiencies and discuss their variations with the parameter: input, ambient temperature and relative humidity. We also carried out seasonal analyses using Pearson's correlation coefficient and find out that the efficiencies are differently dependent on the above mentioned parameters. This arose a new open question on differentiation of the strength of the effect of each parameter on the monthly efficiencies.

关键词： Testing Correlation coefficient Correlation Meteorology Springs Solar energy

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