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Thermal characteristics and regeneration analyses of adsorbents by differential scanning calorimetry and scanning electron microscope

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Journal of Thermal Analysis and Calorimetry 2009年第3期96卷 765-769页

作者： Su, Chung-Hwei Wu, Sheng-Hung Shen, Sun-Ju Shiue, Gong-Yih Wang, Yih-Weng Shu, Chi-Min Department of Fire Science WuFeng Institute of Technology 117 Chian-Kuo Rd. Sec. 2 Min-Hsiung Chia-Yi 62153 Taiwan Doctoral Program Graduate School of Engineering Science and Technology National Yunlin University of Science and Technology 123 University Rd. Sec. 3 Douliou Yunlin 64002 Taiwan Department of Occupational Safety and Health ChiaNan University of Pharmacy and Science 60 Erh-Jen Rd. Sec. 1 Tainan 71710 Taiwan Department of Chemical Engineering and Biotechnology Hsiuping of Technology 11 Gongye Rd. Dali Taichung 41280 Taiwan Department of Occupational Safety and Health Jen-Teh Junior College of Medicine Nursing and Management 1 Jen-Teh Rd. Houlong Miaoli 35601 Taiwan

Volatile organic compounds (VOCs) are the main factors involved in pollution control and global warming in industrialized nations. Various treatment methods involving incineration, adsorption, etc., were employed to reduce VOCs concentration. Various absorbents, such as activated carbon, zeolite, silica gel or alumina, and so on were broadly used to adsorb VOCs in various industrial applications. Differential scanning calorimetry (DSC) was handled to analyze the thermal characteristics of absorbents. Typically, a scanning electron microscope (SEM) has been used to evaluate the structure variation of absorbents under high temperature situations. In view of pollution control and loss prevention, versatility and analysis of recycled adsorbents are necessary and useful for various industrial applications. © 2009 Akadémiai Kiadó, Budapest, Hungary.

关键词： Zeolites

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Hazard evaluation for redox system of cumene hydroperoxide mixed with inorganic alkaline solutions

Hazard evaluation for redox system of cumene hydroperoxide m...

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作者： Hou, H.-Y. Duh, Y.-S. Lee, W.-L. Shu, C.-M. Department of Occupational Safety and Health Jen-Teh Junior College of Medicine Nursing and Management 1 Jen-Teh Rd. Houlong Miaoli 35664 Taiwan Department of Occupational Safety and Health and Graduate Program Chung Shan Medical University 110 Sec.1 Jianguo N. Rd. Taichung 40201 Taiwan Process Safety and Disaster Prevention Laboratory Department of Safety Health and Environmental Engineering National Yunlin University of Science and Technology 123 University Rd. Douliou Yunlin 64002 Taiwan

In petrochemistry, dicumyl peroxide (DCPO) is used in various resins for improving physical properties, which was produced by cumene hydroperoxide (CHP) with oxidization reaction, redox reaction, and dehydration reaction. The reactant, CHP, is a typical organic hydroperoxide and has been intrinsically unstable and reactive due to its bivalent -O-O- structure which can be broken readily with bond-dissociation energy. This sequence on sensitive study aimed at the thermal hazard evaluation for the reactive and incompatible characteristics of CHP mixed with various inorganic alkaline solutions. Differential scanning calorimetry (DSC) and vent sizing package 2 (VSP2) were used to analyze the thermal hazards and runaway reaction of redox system, such as decomposition of CHP in cumene solution and CHP react with inorganic alkaline solutions, exothermic onset temperature, peak power, heat of decomposition of dynamic scanning tests, adiabatic self-heating rate, pressure rise rate, maximum temperature, maximum pressure of reaction system, etc. The results of the tests have proven helpful in establishing safe handling, storage, transportation, and disposal guidelines. © 2009 Akadémiai Kiadó, Budapest.

关键词： Redox reactions

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Integration of micro fluidic bio-chip design and automatic fluorescent identification for rapid sperm mobility assessment

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World Congress on Medical Physics and Biomedical engineering: Micro- and Nanosystems in Medicine, Active Implants, Biosensors

作者： Pan, Li-Chern Hsu, Fang-Chi Wu, Yun-Ying Tseng, Fan-Gang Yao, Da-Jen Tsai, Yieh Loong Hwang, Jiann-Loung Department of General Education Taipei Medical University Taipei Taiwan Department of Public Health Taipei Medical University Taipei Taiwan Graduate Institute of Biomedical Informatics Taipei Medical University Taipei Taiwan Division of Mechanics Research Center for Applied Sciences Academia Sinica Taipei Taiwan Department of Engineering and System Science National Tsing Hua University Hsinchu Taiwan Department of Obstetrics and Gynecology Shin Kong Wu Ho-Su Memorial Hospital Taipei Taiwan

ISBN: (纸本)9783642038860

Since male abnormality has now been reported to account at least thirty percent of couples with fertility problem. Therefore, distinguishing and classification of sperm has become more and more important, especially when Assisted Reproductive Technology (ART) like in vitro fertilization (IVF) is involved. However, traditional sperm sorting methods all requires manual selection, which is tedious and often cause sperm damage during the screen process. Although, new design from our recent study, seemed to point for a possibility to make these kind of MISS device capable of separating sperms into various mobility sub-class. In addition, the Hoechst 33258 and propidium iodide double staining results, also confirmed that the most motile and health sperm is indeed able to leave the laminar stream and being sorted out at outlet-h, with least dead sperm or debris. Meanwhile, we observed the dead sperm had been dominate from clear red stains and live sperm are not as active as is corresponded with more diffused blue stains. In order to confirm the real sorting situation, we counted the amount of sperm in collected sample by flow cytometry and tried to establish the statistic model. Though the flow cytometry, we could detect the sperm fluorescent distribution and count the size of sperm population. Nevertheless, t-test with 95% confidence level also shown significant difference in live/dead sperm ratio. Therefore, from the combined result among flow cytometry, fluorescent stain, and the statistic model test, it is confirmed that live sperms were able to cross the laminar stream created by the device and reach the sorting chamber with corresponding range from non-motile sperms to debris, as well as from living to dead ones. It is concluded that the proposed method is cost effective and is possible to serve as a protocol for rapid sperm quantitative assessment. © 2009 Springer-Verlag.

关键词： Fluorescence

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Hazard evaluation for redox system of cumene hydroperoxide mixed with inorganic alkaline solutions

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Journal of Thermal Analysis and Calorimetry 2009年第2期95卷 541-545页

作者： Hou, H. -Y. Duh, Y. -S. Lee, W. -L. Shu, C. -M. Department of Occupational Safety and Health Jen-Teh Junior College of Medicine Nursing and Management Houlong Miaoli Taiwan ROC Department of Occupational Safety and Health and Graduate Program Chung Shan Medical University Taichung Taiwan ROC Process Safety and Disaster Prevention Laboratory Department of Safety Health and Environmental Engineering National Yunlin University of Science and Technology Douliou Yunlin Taiwan ROC

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Identification of cell cycle-related regulatory motifs using a kernel canonical correlation analysis

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BMC Genomics 2009年第SUPPL. 3期10卷 1-10页

作者： Rhee, Je-Keun Joung, Je-Gun Chang, Jeong-Ho Fei, Zhangjun Zhang, Byoung-Tak Graduate Program in Bioinformatics Seoul National University Seoul 151-744 South Korea Center for Biointelligence Technology (CBIT) Seoul National University Seoul 151-744 South Korea Boyce Thompson Institute for Plant Research Cornell University Ithaca NY 14853 United States Konan Technology Inc Seoul 135-080 South Korea USDA Robert W. Holley Center for Agriculture and Health Ithaca NY 14853 United States School of Computer Science and Engineering Seoul National University Seoul 151-744 South Korea

Background: Gene regulation is a key mechanism in higher eukaryotic cellular processes. One of the major challenges in gene regulation studies is to identify regulators affecting the expression of their target genes in specific biological processes. Despite their importance, regulators involved in diverse biological processes still remain largely unrevealed. In the present study, we propose a kernel-based approach to efficiently identify core regulatory elements involved in specific biological processes using gene expression profiles. Results: We developed a framework that can detect correlations between gene expression profiles and the upstream sequences on the basis of the kernel canonical correlation analysis (kernel CCA). Using a yeast cell cycle dataset, we demonstrated that upstream sequence patterns were closely related to gene expression profiles based on the canonical correlation scores obtained by measuring the correlation between them. Our results showed that the cell cycle-specific regulatory motifs could be found successfully based on the motif weights derived through kernel CCA. Furthermore, we identified co-regulatory motif pairs using the same framework. Conclusion: Given expression profiles, our method was able to identify regulatory motifs involved in specific biological processes. The method could be applied to the elucidation of the unknown regulatory mechanisms associated with complex gene regulatory processes. © 2009 Rhee et al;licensee BioMed Central Ltd.

关键词： Canonical Correlation Analysis Regulatory Motif Upstream Sequence Gene Expression Dataset Yeast Cell Cycle

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Identification of cell cycle-related regulatory motifs using a kernel canonical correlation analysis

Identification of cell cycle-related regulatory motifs using...

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8th International Conference on Bioinformatics: Computational Biology, InCoB 2009

作者： Rhee, Je-Keun Joung, Je-Gun Chang, Jeong-Ho Fei, Zhangjun Zhang, Byoung-Tak Graduate Program in Bioinformatics Seoul National University Seoul 151-744 Korea Republic of Seoul National University Seoul 151-744 Korea Republic of Boyce Thompson Institute for Plant Research Cornell University Ithaca NY 14853 United States Konan Technology Inc. Seoul 135-080 Korea Republic of USDA Robert W. Holley Center for Agriculture and Health Ithaca NY 14853 United States School of Computer Science and Engineering Seoul National University Seoul 151-744 Korea Republic of

关键词： Gene expression

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An executable system architecture approach to discrete events system modeling using SysML in conjunction with Colored Petri Net

An executable system architecture approach to discrete event...

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2008 IEEE International systems Conference Proceedings, SysCon 2008

作者： Wang, Renzhong Dagli, Cihan H. System Engineering Graduate Program Missouri University of Science and Technology 600 W 14th Street Rolla MO 65409-0370 United States

ISBN: (纸本)9781424421503

This paper proposes an executable system architecting paradigm for discrete event system modeling and analysis through integration of a set of architecting tools, executable modeling tools, analytical tools, and visualization tools. The essential step is translating SysML-based specifications into Colored Petri Nets (CPNs) which enables rigorous static and dynamic system analysis as well as formal verification of the behavior and functionality of the SysML-based design. A set of tools have been studied and integrated that enable a structured architecture design process. Some basic principles of executable system architecture for discrete event system modeling that guide the process of executable architecture specification and analysis are discussed. This paradigm is aimed at general system design. Its feasibility was demonstrated with a C4type network centric system as an example. The simulation results was used to check the overall integrity and internal consistency of the architecture models, refine the architecture design, and, finally, verify the behavior and functionality of the system being modeled. ©2008 IEEE.

关键词： Discrete event simulation

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PI3-kinase-dependent activation of apoptotic machinery oc-curs on commitment of epidermal keratinocytes to terminal differentiation

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细胞研究(英文版) 2009年第3期19卷 328-339页

作者： Sam M Janes Tyler A Ofstad Douglas H Campbell Ayad Eddaoudi Gary Warnes Derek Davies Fiona M Watt Centre for Respiratory Research Rayne Institute University College London 5 University Street London WCIE 6BT UK Graduate Program in Neurosciences University of California San Diego CA 92093-0662 USA Immune System Therapeutics Ltd 235 Jones Street Ultimo NSW 2007 Australia Molecular Immunology Unit Institute of Child Health University College London 30 Guilford Street London WCIN 1EH UK Institute of Cell and Molecular Science Barts and The London School of Medicine and Dentistry 4 Newark Street London E1 2AT UK Cancer Research UK London Research Institute 44 Lincoln's Inn Fields London WC2A 3PX UK Cancer Research UK Cambridge Research Institute Li Ka Shing Centre Robinson Way Cambridge CB2 ORE UK

We have investigated the earliest events in commitment of human epidermal keratinocytes to terminal differen-tiation. Phosphorylated Akt and caspase activation were detected in cells exiting the basal layer of the epidermis. Activation of Akt by retroviral transduction of primary cultures of human keratinocytes resulted in an increase in abortive clones founded by transit amplifying cells, while inhibition of the upstream kinase, Pl3-kinase, inhibited suspension-induced terminal differentiation. Caspase inhibition also blocked differentiation, the primary mediator being caspase 8. Caspase activation was initiated by 2 h in suspension, preceding the onset of expression of the termi-nal differentiation marker involucrin by several hours. Incubation of suspended cells with fibronectin or inhibition of PI3-kinase prevented caspase induction. At 2 h in suspension, keratinocytes that had become committed to terminal differentiation had increased side scatter, were 7-aminoactinomycin D (7-AAD) positive and annexin V negative; they exhibited loss of mitochondrial membrane potential and increased cardiolipin oxidation, but with no increase in reac-tive oxygen species. These properties indicate that the onset of terminal differentiation, while regulated by Pl3-kinase and caspases, is not a classical apoptotic process.

关键词： epidermis integrins extracellular matrix

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Association between periodontitis and anti-cardiolipin antibodies in Buerger disease

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Journal of Clinical Periodontology 2009年第10期36卷 830-835页

作者： Chen, Yi-Wen Nagasawa, Toshiyuki Wara-Aswapati, Nawarat Ushida, Yuka Wang, Dongqing Takeuchi, Yasuo Kobayashi, Hiroaki Umeda, Makoto Inoue, Yoshinori Iwai, Takehisa Ishikawa, Isao Izumi, Yuichi Department of Hard Tissue Engineering Graduate School Tokyo Medical and Dental University Tokyo Japan National Taiwan University Hospital National Taiwan University Taipei Taiwan Department of Periodontology Faculty of Dentistry Khon Kaen University Khon Kaen Thailand Department of Periodontics and Oral Medicine Beijing Stomatological Hospital Capital Medical University Beijing China Department of Vascular and Applied Surgery Graduate School Tokyo Medical and Dental University Tokyo Japan Tsukuba Vascular Center Buerger Disease Research Institute Ibaragi Japan Institute of Advanced Biomedical Engineering and Science Tokyo Women's Medical University Tokyo Japan Global Center of Excellence Program International Research Center for Molecular Science in Tooth and Bone Diseases Tokyo Medical and Dental University Tokyo Japan Department of Periodontology and Endodontology Health Science University of Hokkaido Ishikari-gun Hokkaido 061-0293 1757 Kanazawa Tobetsu-cho Japan

Aim: Anti-cardiolipin (CL) antibodies can be induced in Buerger disease (BD), an inflammatory occlusive disorder affecting peripheral blood vessels, in response to bacteria bearing homology to the TLRVYK peptide of a phospholipid-binding plasma protein β-2-glycoprotein I. TLRVYK homologies are present in Porphyromonas gingivalis (TLRIYT) and Treponema denticola (TLALYK). This study investigated the association between periodontal infection and anti-CL antibodies in BD patients. Material and Methods: Periodontal conditions were examined in 19 BD patients and 25 systemically healthy control subjects. All subjects were heavy smokers. Serum anti-CL, anti-TLRVYK, anti-TLRIYT, and anti-TLALYK antibodies were assessed using the enzyme-linked immunosorbent assay. Results: BD patients had a significantly higher prevalence of periodontitis, more severe periodontal destruction and increased titres of serum anti-CL, anti-TLRVYK, anti-TLRIYT, and anti-TLALYK antibodies compared with healthy subjects. The levels of anti-CL antibodies positively correlated with those of the three anti-peptide antibodies. Anti-CL antibody titres were significantly associated with the percentage of sites with clinical attachment level ≥4 mm in BD patients. Conclusion: Elevated anti-CL antibody levels were associated with periodontal destruction in BD patients. Periodontopathic bacteria may serve as exogenous antigens that stimulate the anti-CL antibody production through molecular mimicry between the bacterial peptides and a host plasma protein. © 2009 John Wiley & Sons A/S.

关键词： β-2-glycoprotein I Anti-cardiolipin antibody Buerger disease Molecular mimicry Periodontitis

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R & D of ray tracing simulation software and fabrication technologies based on VCAD (Volume-CAD) concept for GRIN lens

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Key engineering Materials 2008年 381-382卷 109-112页

作者： Itani, N. Watanabe, Y. Lin, W. Uehara, Y. Morita, S. Mishima, T. Ohmori, H. Makinouchi, A. Graduate School of Science and Engineering Saitama University 255 Shimo-Okubo Sakura-ku Saitama City Saitama 338-8570 Japan VCAD System Research Program CIPS RIKEN 2-1 Hirosawa Wako-shi Saitama 351-0198 Japan

We have been developing an intellectual manufacturing process applying IT (V-Cam system fabrication processes) based on Volume-CAD (VCAD) system which can express internal information of materials. This paper introduces the ultra-precision grinding, ray tracing (optical path) simulation software 'V-Opt' and the measurement of actual optical functions in the development of optical element taking gradient refractive index (GRIN) lens with functionally graded material properties as a model. In finish ground GRIN lens using SD#8000 wheel, the P-V (Peek to Value) of 27.07 nm, surface roughness (Ra) of 1.83 nm is obtained. 'V-Opt' developed for GRIN lens have two main functions;one is the visualizations of ray tracing and the other is the evaluation of spot diagram and focal length.

关键词： Grinding (machining)

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