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55th Society of Polymer Science Japan Symposium on Macromolecules

作者： Matsumoto, Keigo Minagawa, Keiji Tanaka, Masami Mori, Takeshi Niidome, Takuro Katayama, Yoshiki Graduate School of Systems Life Sciences Kyushu University 744 Motooka Fukuoka-shi Fukuoka 819-0395 Japan Graduate School of Engineering Tokushima University 2-1 Mishimacyo Tokushima-shi Tokushima 770-8506 Japan Faculty of Pharmaceutical Science Tokushima Bunri University 180 Nishihamahouji Yamashiro-cho Tokushima-shi Tokushima 770-8514 Japan Graduate School of Engineering Kyushu University 744 Motooka Nishi-ku Fukuoka 819-0395 Japan Center for Future Chemistry Kyushu University Grant-in-Aid for 21st Century COE Program

We synthesize novel thermos ens itive Polymerl that has rektively large thermal hysteresis. Phase transition temperature of Polymer 1 is 37.9°C for heating process and 30.7°C for cooling one. When Polymer 1 was heated at at 45°C and cooling at 35°C for 16h, the polymer solution remained phase separated. We injected the polymer solution into caudal vein of a mouse and warmed around the injected area. We observed a long term obturation of the vessel.

关键词： Blood vessel prostheses

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Journal of Scheduling: Editorial

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Journal of Scheduling 2006年第3期9卷 199-201页

作者： Bard, Jonathan F. Barnhart, Cynthia Graduate Program in Operations Research 1 University Station C2200 University of Texas Austin TX 78712 United States Civil and Environmental Engineering and Engineering Systems Massachusetts Institute of Technology Cambridge MA 02139 United States

No abstract available

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A biomimetic MEMS neurotransmitter detector

A biomimetic MEMS neurotransmitter detector

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10th International Conference on Miniaturized systems for Chemistry and Life Sciences, MicroTAS 2006

作者： Koev, Stephan T. Wu, Li-Qun Payne, Gregory F. Ghodssi, Reza Department of Electrical and Computer Engineering University of Maryland College Park MD 20742 United States Institute for Systems Research University of Maryland College Park MD 20742 United States University of Maryland Biotechnology Institute University of Maryland College Park MD 20742 United States Bioengineering Graduate Program University of Maryland College Park MD 20742 United States

We demonstrate, for the first time, micromechanical detection of the neurotransmitter dopamine and its discrimination from ascorbic acid. Microcantilever sensors were fabricated and coated with the polysaccharide chitosan by electrodeposition. The cantilevers were used for electrochemical oxidation of dopamine solution. The products of this reaction crosslink the chitosan film and create a tensile stress, bending the cantilever out of plane considerably. By contrast, electrochemical oxidation of ascorbic acid solution does not cause chitosan crosslinking and appreciable cantilever bending. This method is an improvement over conventional electrochemical dopamine detection techniques (e.g. cyclic voltammetry) that are highly non-specific. © 2006 Society for Chemistry and Micro-Nano systems.

关键词： Chitosan

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Electromagnetic Device Optimization using Improved Differential Evolution Methods

Electromagnetic Device Optimization using Improved Different...

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IEEE Conference on Electromagnetic Field Computation

作者： L. dos Santos Coelho P. Alotto Rcductim and Systems Engineering Gmduale Rogmm Aulmation and Systms Labaratcry PUCPR/PPGEPS/LAS Pontifical Catholic University of Paraná Curitiba Parana Brazil Production and Systems Engineering Graduate Program Aulmation and Systms Labaratory Curitiba Parana Brazil Dip. Inssgneria Eldtrica UnivslniU di I'adovn Italy

Recently, evolutionary algorithms (e.g. genetic algorithms, evolutionary programming, and evolution strategies) have proven to be useful tools for the optimization of difficult problems in electromagnetics. Differential evolution (DE) is one comparatively simple variant of an evolutionary algorithm using floating-point encoding and few control parameters. This work presents improved DE algorithms based on linearly time varying control parameters, sinusoidal functions, and diversity analysis of population

关键词： Electromagnetic devices Optimization methods Algorithm design and analysis Evolutionary computation USA Councils Writing Differential equations Encoding Convergence of numerical methods Testing

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A genetic algorithm for the optimization of cable routing

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systems and Computers in Japan 2006年第7期37卷 61-71页

作者： Ma, Xuan Iida, Kazuhiro Xie, Mengchun Nishino, Junji Odaka, Tomohiro Ogura, Hisakazu Graduate School of Engineering University of Fukui Fukui City 910-8507 Japan Wakayama National College of Technology Gobo City 644-0023 Japan Faculty of Automation and Information Engineering Xi an University of Technology B Techno College Department of Electrical and Computer Engineering Wakayama National College of Technology Information Processing Society of Japan China Mechanical Design Society Department of Systems Engineering University of Electro-Communications Japan Society for Fuzzy Theory and Intelligent Informatics Japanese Academy of Facial Studies Japan Society of Kansei Engineering Graduate Program of Nuclear Power and Energy Safety Engineering Graduate School of Engineering Fukui University IEEE CS ACM IPSJ IEICE JSMBET Department of Human and Artificial Intelligent Systems JSAI Japan SOFT IEEE

In this paper the authors propose a structural method for a genetic algorithm (GA) for the optimization problem of cable routing in which cables have to be laid optimally. When there are no limits on the layout routes, the optimal routes for the individual cables can be found using the Dijkstra method in a finite discrete graph. However, when there are limits on the capacity in the layout routes, optimization cannot be performed using the Dijkstra method. The proposed GA is a two-level hierarchical GA that uses chromosome coding involving two levels. The routes for each cable and the combinations of cable routes are defined respectively, and layout route selection is optimized overall through genetic operations involving these levels. Block crossover and block mutation are used as genetic operations in the first level. In addition, a method to take advantage of lethal genes, which do not satisfy the constraints and are generated in the second level is used. Computer simulations confirm that the two-level hierarchical GA with these genetic operations functions effectively for the optimization problem of cable routing. © 2006 Wiley Periodicals, Inc.

关键词： Electric cable laying

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Integral videography autostereoscopic display using multiprojection

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systems and Computers in Japan 2006年第5期37卷 34-45页

作者： Liao, Hongen Iwahara, Makoto Koike, Takefumi Momoi, Yasuyuki Hata, Nobuhiko Sakuma, Ichiro Dohi, Takeyoshi Graduate School of Engineering University of Tokyo Tokyo 113-8656 Japan Z-axis Ltd. Japan Hitachi Ltd. Tokyo 101-8010 Japan Graduate School of Frontier Sciences University of Tokyo Tokyo 113-8656 Japan Graduate School of Information Science and Technology University of Tokyo Tokyo 113-8656 Japan Nano Bioengineering Education Program Graduate School of Engineering University of Tokyo Z-axis Ltd. Systems Development Laboratory Hitachi Ltd. Graduate School of Information Science and Technology University of Tokyo Institute of Environmental Studies Graduate School of Frontier Sciences University of Tokyo

Various techniques of autostereoscopic three-dimensional (3D) display for displaying real 3D information have been investigated in recent years. We have performed research and application of integral videography (IV), which is an animated display technique based on the principle of integral photography (IP). Although IV and IP are ideal ways to display 3D images, their spatial viewing resolution and high-speed image rendering algorithm must be improved. The pixel pitch of the display and the lens pitch are the main factors affecting IV image quality. We improved the image quality by increasing the number and density of the pixels. Parallel image processing and displaying method were also developed for animated IV imaging. We have created a scalable high-resolution image using multiple projection and project it onto a small screen to achieve high-density pixels using long-focal-length projection optics. Furthermore, an image calibration method was developed for geometrical correction and color modulation to generate seamless IV images. We evaluated the developed device by displaying an X-ray computed tomography (CT) image. Measurement of the geometrical accuracy of the reproduced IV images demonstrated that the spatial resolution of the display system matched that by theoretical analysis. Experimental results showed that our technique is very effective in obtaining 3D animated images with practical spatial resolution. © 2006 Wiley Periodicals, Inc.

关键词： Display devices

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DNA complex formed with peptide-grafted polymer responding with tyrosine kinase 'c-Src'

DNA complex formed with peptide-grafted polymer responding w...

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55th SPSJ Annual Meeting

作者： Sato, Yuko T. Oishi, Jun Kawamura, Kenji Terada, Keiko Asai, Daisuke Kang, Jeong-Hun Katayama, Yoshiki JST-CREST Kyushu University 744 Motooka Nishi-ku Fukuoka 819-0395 Japan Department of Applied Chemistry Faculty of Engineering Kyushu University 744 Motooka Nishi-ku Fukuoka 819-0395 Japan Graduate School of Systems Life Sciences Kyushu University 744 Motooka Nishi-ku Fukuoka 819-0395 Japan Center for Future Chemistry Kyushu University 744 Motooka Nishi-ku Fukuoka 819-0395 Japan COE Program

We aim to create gene delivery system responding to cellular signal i.e. exogenous DNAs are translated only in cancer cells. First, we synthesized polymer that grafted c-Src substrate peptide as gene carrier. Next, we generated complex with those polymer and DNA. In this meeting, we will report about characterization of DNA-carrier complex, and the ability of carrier to control transcription/ translation and protection of DNA.

关键词： DNA

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Correction to "Combining of Chaotic Differential Evolution and Quadratic programming for Economic Dispatch Optimization with Valve-Point Effect"

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IEEE Transactions on Power systems 2006年第3期21卷 1465-1465页

作者： L. Dos Santos Coelho V.C. Mariani Production and Systems Engineering Graduate Program Automation and Systems Laboratory PUCPR/CCET/PPGEPS/LAS Pontifical Catholic University of Paraná Curitiba Parana Brazil Mechanical Engineering Graduate Program PUCPR/CCET/PPGEPS/LAS Pontifical Catholic University of Paraná Curitiba Parana Brazil

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Real-time organ motion tracking and fast image registration system for MRI-guided surgery

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systems and Computers in Japan 2006年第1期37卷 83-92页

作者： Tokuda, Junichi Hirano, Masaya Tsukamoto, Tetsuji Dohi, Takeyoshi Hata, Nobuhiko Graduate School of Information Science and Technology University of Tokyo Tokyo 113-8656 Japan GE Yokogawa Medical Systems Ltd. Hino 191-8503 Japan International Society for Computer-Aided Surgery Japan Society for Computer-Aided Surgery Japan Society for Magnetic Resonance in Medicine GE Yokogawa Medical Systems Ltd. Imaging Application Tech. Center MR Group R and D Laboratory Technology Center GE Yokogawa Medical Systems Ltd. Society for Magnetic Resonance in Medicine Graduate School of Information Science and Technology Society for Life Support Technology Japan Society for Organ Preservation Biology and Medicine Society for Precision Engineering Society for Medical Image Computing and Computer Assisted Intervention International Union for Physics and Engineering Sciences in Medicine JSMEBE Japan Society for Life Assistance Technology Brigham and Women's Hospital Harvard Medical School MR Therapy Program

The advantage of magnetic resonance imaging (MRI)-guided surgery, in which MR images taken during surgery are used to guide the surgery, has been recognized recently. However, there is a problem, due to long imaging time of MRI, that it is difficult to capture the respiratory organ motion. It is often a constraint that the patient must hold his or her breath, especially in the treatment of the abdominal region. Consequently, this paper proposes a method of eliminating this constraint in MRI-guided surgery by real-time monitoring of the movement of the organ involved in the surgery by means of the signal derived from MRI. Specifically, the navigator echo is extracted in imaging during surgery. The movement of the organ involved in surgery is detected on the basis of the change in the calculated projection profile, and the results are presented to the surgeon. In this study, the procedure is built into a 1.5-T clinical MRI system. The feasibility of the proposed system was examined under clinical conditions by evaluating its accuracy and delay in a phantom experiment, and also in an in vivo experiment on the liver of a volunteer. The results are reported in this paper. © 2005 Wiley Periodicals, Inc.

关键词： Motion estimation

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Chitosan for Biofunctionalization of Microsystems

Chitosan for Biofunctionalization of Microsystems

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IEEE/NLM Life Science systems and Applications Workshop

作者： Stephan T. Koev Michael A. Powers Vlad Badilita Hyunmin Yi William E. Bentley Gregory F. Payne Gary W. Rubloff Reza Ghodssi Institute for Systems Research ISR University of Maryland College Park MD USA University System of Maryland Adelphi MD US Department of Materials Science and Engineering University of Maryland College Park MD USA Department of Chemical Engineering University of Maryland College Park MD 20742 University of Maryland Biotechnology Institute (UMBI) University of Maryland College Park MD 20742 Bioengineering Graduate Program University of Maryland College Park MD 20742 University of Maryland College Park MD USA University of Maryland Biotechnology Institute College Park MD USA Institute for Systems Research (ISR) University of Maryland College Park MD 20742 Department of Materials Science and Engineering University of Maryland College Park MD 20742 Department of Electrical and Computer Engineering University of Maryland College Park MD 20742 Institute for Systems Research (ISR) University of Maryland College Park MD 20742

ISBN: (纸本)1424402778

We present the use of the polysaccharide chitosan for immobilizing biomolecules on microfabricated device surfaces. The main advantages of chitosan are its abundance of primary amine groups and its ability to be electrodeposited. Biomolecules are easily attached to chitosan 's amines by standard glutaraldehyde chemistry. The electrodeposition of chitosan allows accurate spatial and temporal control of biomolecule placement. We have demonstrated this biofunctionalization method for two different bioMEMS devices: a biophotonic sensor and a micromechanical biosensor. We have successfully assembled probe DNA on each of them and detected hybridization with target DNA as a demonstration of sensor operation. Here, we briefly present the fabrication procedure and testing results for both of these bioMEMS sensing devices

关键词： DNA Biosensors Molecular biophysics Probes Micromechanical devices Optical sensors Optical surface waves Optical interferometry Assembly Biomedical optical imaging

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