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25th Annual Computational Neuroscience Meeting CNS-2016, Seogwipo City, South Korea, July 2-7, 2016 Abstracts

BMC NEUROSCIENCE 2016年第1期17卷 1-112页

作者： [Anonymous] Computational Neurobiology Laboratory The Salk Institute for Biological Studies San Diego USA UNIC CNRS Gif sur Yvette France The European Institute for Theoretical Neuroscience (EITN) Paris France ATR Computational Neuroscience Laboratories Kyoto Japan Krembil Research Institute University Health Network Toronto Canada Department of Physiology University of Toronto Toronto Canada Department of Medicine (Neurology) University of Toronto Toronto Canada Department of Physics University of New Hampshire Durham USA Department of Neurophysiology Nencki Institute of Experimental Biology Warsaw Poland Department of Theory Wigner Research Centre for Physics of the Hungarian Academy of Sciences Budapest Hungary Department of Mathematical Sciences KAIST Daejoen Republic of Korea Department of Mathematics University of Houston Houston USA Department of Biochemistry & Cell Biology and Institute of Biosciences and Bioengineering Rice University Houston USA Department of Biology and Biochemistry University of Houston Houston USA Grupo de Neurocomputación Biológica Dpto. de Ingeniería Informática Escuela Politécnica Superior Universidad Autónoma de Madrid Madrid Spain Department of Biological Sciences University of Southern California Los Angeles USA Center for Neuroscience Korea Institute of Science and Technology Seoul South Korea Department of Neurology Albert Einstein College of Medicine Bronx USA Center for Neuroscience KIST Seoul South Korea Department of Neuroscience University of Science and Technology Daejon South Korea Systems Neuroscience Group QIMR Berghofer Medical Research Institute Herston Australia Department of Psychology Yonsei University Seoul South Korea Department of Psychiatry Kyung Hee University Hospital at Gangdong Seoul South Korea Department of Psychiatry Veterans Administration Boston Healthcare System and Harvard Medical School Brockton USA Department of Electrical and Electronic Engineering The University of Melbourne Parkvil

A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni

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U. S. NAVAL ACADEMY'S NEW YARD PATROL CRAFT: FROM CONCEPT TO DELIVERY.

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Naval Engineers Journal 1987年第1期99卷 37-58页

作者： Compton, Roger H. Chatterton, Howard A. Hatchell, Gordon McGrath, Frank K. Roger H:. Compton is a Webb graduate who since 1966 has been a part of the naval architecture faculty at the U.S. Naval Academy. Since accepting the appointment to the Academy he has been instrumental in establishing the ABET accredited major program in naval architecture in the conceptual design and operation of the Naval Academy Hydromechanics Laboratory and in the conceptual design of the 108-ft yard patrol craft. Besides his Naval Academy involvement he serves as an adjunct professor with Virginia Polytechnic Institute in its NAVSEA Institute graduate program at Crystal City. He is an active member of both ASNE and SNAME and has published technical papers with both societies. Howard A. Chatterton:began his career as a Navy coop student at the Boston Naval Shipyard in 1960. He received his bachelor's degree in naval architecture and marine engineering from Massachusetts Institute of Technology in 1966 and his master's degree in 1968. He was employed by the Preliminary Design Division of BuShips in the submarine design and hydrofoil design groups until 1972 when he joined the Coast Guard's Naval Engineering Division. He remained with the Design Branch until 1981 when he accepted a faculty position at the U.S. Naval Academy as the research director for the Academy's hydromechanics laboratory. He has recently returned to Coast Guard Headquarters as the assistant chief Naval Architecture Branch Office of Merchant Marine Safety. Gordon Hatchell:is a naval architect at the Naval Sea Combat Systems Engineering Station Norfolk Virginia in the Combatant Craft Engineering Department. He served as lead-ship YP project engineer from its inception to delivery and continues to serve as project coordinator on follow-up ship procurements. He has worked on other boat procurements as well as serving as weight and stability coordinator. Mr. Hatchell began his engineering career in the Design Division at the Norfolk Naval Shipyard in Portsmouth Virginia after receiving a BS in civil engineering from Virginia Polytec

The design of the new 108-ft yard patrol craft (YPs) for the U. S. Naval Academy is described from its beginnings as a senior midshipman design project, through its preliminary and contract design development at the U. S. Navy's small craft design team headquarters, Naval Sea Combat systems engineering Station, Norfolk, Virginia (NAVSEACOMBAT-SYSENGSTA-Norfolk). During preliminary and contract design the Naval Academy Hydromechanics Laboratory (NAHL) provided experimental data to support NAVSEA-COMBATSYSENGSTA-Norfolk's design analyses in powering, seakeeping, and maneuvering. Several tradeoff studies of interest to patrol craft designers are presented. Major events in the detail design and construction of the first boat are described from both the designer's and the shipbuilder's points of view. The launching, builder's and sea trials of the first boat are described.

关键词： NAVAL VESSELS

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2001: THE AGE OF SHIP CONTROL

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Naval Engineers Journal 1970年第2期82卷 13-22页

作者： MURPHY, RICHARD J. THE AUTHOR: is a graduate of Northeastern University in Boston Massachusetts where he received degrees in Mechanical Engineering and in Engineering and Managment. He is presently the Head Analyst in the Exploratory Development Division of Headquarters Naval Material Command. Since 1964 he has acted as leader of a team developing goals for exploratory development for the undersea target the air target and the land and surface target. From 1961 to 1964 he was with the Advanced Manned Missions Program Office of the NASA involved with the study of advanced launch vericle concepts for future manned orbital and manned planetary missions. Prior to this he was NASA's Headquarters Manager of the Saturn I and Saturn IB launch facilities located at the J. F. Kennedy Space Center. From 1954 to 1961 Mr. Murphy was employed by the Navy in BUSHIPS BUAIR and BUWEPS. His duties were primarily associated with R&D of non-magnetic minesweepers and new guided missile systems.

A variety of probable world political environments are postulated. From these environments, possible concepts for future warships, merchant ships, salvage ships, and research vehicles, both on the surface and undersea, are discussed. A forecast is made of the ship control systems requirements for these future ship concepts of the 21st century;and the needs for action today are highlighted. Because we can project the future best when we fully understand the past, such a history is included where suitable. Trends in ship control systems are traced up to the present time when navigation is assisted by spacecraft orbiting the earth, and these trends are projected into a future of high speed, unmanned and automated seapower. © 1970 by the American Society of Naval Engineers, Inc.

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CENTML CONTROL SYSTEM TRAINING THROUGH STA TIC AND DYNAMIC SIMULATION

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Naval Engineers Journal 1980年第2期92卷 196-206页

作者： HALL, EDWIN E. MOSS, DONALD G. NORRIS, CLIFFORD S. PETERSON, HAROLD D. Mr. Edwin E. Hall received his Bachelor's degree in Electronics from Oklahoma City University. He also is a certified College-Level Instructor in the state of Florida and has done graduate work in Computer Science at the University of Florida. As the Technical Publications and Training Manager Simulation and Control Systems Department. General Electric Company Daytona Beach Fla. he currently is responsible for the costing. planning performance scheduling and timely completion of the Department's Technical Manuals and Technical Training Programs. These Training and Manual contracts cover Ship Systems Programs. Simulation Programs. and Communications Programs for the Armed Services and commercial customers. Mr. Hall has over twenty-years experience as a Technical Writer and Instructor and for the past seventeen years has been at the General Electric Company's Daytona Beach Facility. His experience ranges from teaching Basic Electronics and Radar Circuitry as a civilian instructor for the U.S. Army to writing Manuals Proposals Reports Specifications and Brochures for General Electric's product lines. Mr. Donald G. MOSS is a graduate of Kansas State University from which he received both his B.S. degree in Business Administration and his M.S. degree in Electrical Engineering. He is presently a Senior Systems Engineer for Control Systems in the Simulation and Control Systems Department at the General Electric Company's Daytona Beach Facility. He has been employed by General Electric for 23 years — the first seven as an Engineer and Program Manager on the Fire Control Systems for the Fleet Ballistics Missile Program the next six managing the design of control and checkout equipment on the APOLLO Program and the last ten years working on control equipment for the machinery plants of new Navy ships. Over the span of years at General Electric he has worked on propulsion control for the DD-963 propulsion electric plant and auxiliary control for the FFG-7: propulsion boiler burner electric auxiliary and car

Dynamic Simulation is defined as the hardware and software required to present to the student operator visual and audible cues and responses that are the same as those encountered when operating the Control Consoles aborad ship. This type of simulation is considered essential to the development of operator skills for critical tasks. Less critical tasks can be practiced using static simulation devices. This paper discusses the utilization of these types of training devices to train Navy crews. An overview of the Machinery Control systems of the FFG 7 and AO 177 Class ships is discussed to provide an understanding of state‐of‐the‐art equipment development. The training programs for these two ship Classes are then reviewed to show how simulation devices are currently used by the Training Community, and this is followed by a brief discussion of the additional benefits that also are derived. © 1980 by the American Society of Naval Engineers, Inc.

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AN EXPANDED GENETICALLY ENCODED VOLTAGE INDICATOR TOOLBOX FOR DEEP, RAPID, AND PROLONGED VOLTAGE RECORDINGS IN VIVO

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IBRO Neuroscience Reports 2023年 15卷 S264-S265页

作者： Shuyuan Yang Xiaoyu Lu Michelle Land Zhuohe Liu Alex Mcdonald Yueyang Gou Yunmiao Wang Elsayed Zaabout Xiaoyu Dong Shujuan Lai Dieter Jaeger Jacob Reimer François St-Pierre Rice University Department Of Chemical And Biomolecular Engineering Houston United States of America Rice University Systems Synthetic And Physical Biology Program Houston United States of America Baylor College of Medicine Department Of Neuroscience Houston United States of America Emory University Department Of Biology Atlanta United States of America Emory University Neuroscience Graduate Program Atlanta United States of America Baylor College of Medicine Center For Neuroscience And Artificial Intelligence Houston United States of America Rice University Department Of Electrical And Computer Engineering Houston United States of America Baylor College of Medicine Department Of Biochemistry And Molecular Biology Houston United States of America

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Changing the public perception of human embryology ( vol 25, pg 1717, 2023)

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NATURE CELL BIOLOGY 2023年第12期25卷 1884-1884页

作者： Rivron, Nicolas C. Martinez-Arias, Alfonso Sermon, Karen Mummery, Christine Scholer, Hans R. Wells, James Nichols, Jenny Hadjantonakis, Anna-Katerina Lancaster, Madeline A. Moris, Naomi Fu, Jianping Sturmey, Roger G. Niakan, Kathy Rossant, Janet Kato, Kazuto Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) Vienna BioCenter (VBC) Vienna Austria Systems Bioengineering MELIS Universidad Pompeu Fabra and Catalan Institution for Research and Advanced Studies (ICREA) Barcelona Spain Research Group Reproduction and Genetics Vrije Universiteit Brussel Brussels Belgium European Society for Human Reproduction and Embryology (ESHRE) Strombeek-Bever Belgium Leiden University Medical Center Leiden the Netherlands Max Planck Institute for Molecular Biomedicine Münster Germany Center for Stem Cell and Organoid Medicine Cincinnati Children’s Hospital Medical Center Cincinnati OH USA Division of Developmental Biology Cincinnati Children’s Hospital Medical Center Cincinnati OH USA MRC Human Genetics Unit Institute of Genetics and Cancer The University of Edinburgh Crewe Road Edinburgh UK Developmental Biology Program Sloan Kettering Institute Memorial Sloan Kettering Cancer Center New York NY USA MRC Laboratory of Molecular Biology Cambridge UK The Francis Crick Institute London UK Department of Mechanical Engineering University of Michigan Ann Arbor MI USA Department of Biomedical Engineering University of Michigan Ann Arbor MI USA Department of Cell & Developmental Biology University of Michigan Medical School Ann Arbor MI USA Biomedical Institute for Multimorbidity Hull York Medical School University of Hull Hull UK Cambridge Reproduction University of Cambridge Cambridge UK The Centre for Trophoblast Research Department of Physiology Development and Neuroscience University of Cambridge Cambridge UK Human Embryo and Stem Cell Laboratory The Francis Crick Institute London UK Wellcome Trust–Medical Research Council Stem Cell Institute University of Cambridge Jeffrey Cheah Biomedical Centre Cambridge UK Epigenetics Programme Babraham Institute Cambridge UK The Hospital for Sick Children Toronto ON Canada Department of Biomedical Ethics and Public Policy Graduate School of Medicin

Human embryology is flourishing thanks to an impetus provided by embryo models formed from stem cells. These scientific advances require meticulous experimental work and a refined ethical framework, but also sensible ... 详细信息

关键词： Embryology Embryonic stem cells

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FOCAS - A NEW LOOK IN COMBAT SYSTEM SIGNAL TRANSMISSION

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NAVAL ENGINEERS JOURNAL 1983年第3期95卷 51-62页

作者： SLEMON, CS ABBOTT, JW Charles S. Slemon:graduated from Brown University with an Sc.B. Degree in Physics and did graduate work in semiconductors at the School of Electrical Engineering Cornell University sity receiving an M.S. degree. In 1972 he received an NSF grant to study the temperature dependence of crystal structures and while at Cornell he developed various fabrication and testing techniques with new semiconductor compounds. Upon joining Tetra Tech Inc. in 1976 he established and is responsible for their fiberoptic laboratory. He has carried out many programs involved in fiberoptic links for secure communication for various government agencies in which he authored numerous classified reports and developed special fiberoptic devices and system. He has also carried out studies and hardware development and evaluation programs for the military and commercial clients including marine and deep sea uses of fiberoptics for NOSC ONR and other off-shore industry contractors. For NAVSEA he authored several reports investigating the potential uses and advantages that fiberoptic technology offers to Navyshipboard operations. Mr. Slemon has published many articles and made numerous presentations in the field of fiberoptics. He has also taught several short courses on the subject and is the holder of several patents. Mr. Jack W. Abbott:received his BSME degree from Stanford University in 1960 and his Masters (MEA) degree from George Washington University in 1975. He holds a Professional Engineer License in the state of California. Mr. Abbott served as a naval officer – aboard a destroyer for 3 years. He worked for the Garrett Corporation for nearly 8 years involved with gas turbine design development and application. For the last 15 years Mr. Abbott has been directly involved with all aspects of destroyer design including the Canadian DDH 280 U.S. DD 963 and DD 993 destroyers. Currently Mr. Abbott is the NAVSEA Program Manager of the Ship Systems Engineering Standards (SSES) Program – responsible for developing combat system inter

This article introduces the concept of a truly Universal Signal Distribution Network. The emergence of fiberoptic technology as a viable signal transmission medium now gives the N avy the opportunity to use Fiber Optic Cabling and Switching (FOCAS) to implement a universal network. A FOCAS Network can handle all present or future shipboard signal distribution architectures such as point-to-point or data bus. Furthermore, compared to existing cable installations, this network offers lower cost through reduction of the number of cables, weight, and volume, freedom from interference and EMP effects, increased redundancy, and higher operational flexibility. In addition, it will easily satisfy all future expansion or changes in signal distribution by providing at least a ten fold increase in data rate capacity over existing electrical cabling. This last feature alone holds the potential for allowing upgrading and conversion of modern combat systems without need for adding new cabling in the ship. Along with the introduction of the concept of a Universal FOCAS network and its practical benefits and capabilities, this article presents a trade-off between the Radar Data Distribution Network on the FFG and an analogous FOCAS network. Though far from optimized, the resultant FOCAS network shows that the conversion of existing shipboard networks to FOCAS is straightforward and provides a reduction of at least 90% in cable volume and weight and lower cost in cable purchase and installation.

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SHIP ENERGY-CONSERVATION ASSIST TEAM (SECAT)

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NAVAL ENGINEERS JOURNAL 1984年第2期96卷 47-58页

作者： DANGEL, R BRICE, AE The Authors A. Edward Brice was born and educated in Scotland where he graduated from the James Watt Memorial College and Paisley Technical College. His earliest marine engineering experience was obtained at Scotts's Shipbuilding and Engineering Company Limited from 1952 to 1959 where he was involved in the production and design of steam and diesel machinery plants for both Naval and commercial ships. During a five year stay in Canada Mr. Brice gained diversified experience in industries other than marine such as petrochemical plants and steel mills. He moved to the U.S. in 1964 where he was the design supervisor in charge of marine engineering at NASSCO covering new construction for American President Lines AFS type ships for the U.S. Navy Project Mohole Car Ferries for the State of Washington and 17 LST's for the U.S. Navy. During the contract definition phase of the DD-963 Mr. Brice authored several portions of the technical proposal while employed by Litton industries. He was also responsible for the system and detail design including the technical management of sub-contracts for the steam propulsion plant for the LHA 1 Class ships. Mr. Brice has been active in the Washington area for the last ten years performing marine engineering projects for the U.S. Navy. His principal interest since 1974 has been in shipboard energy conservation. He assisted in the development of the NavySTMSYS program and later in the operational verification aboard FF-1074. Mr. Brice has conducted four SECA T visits aboard ships with 1200 PSI steam plants and has recently completed an at-sea visit aboard on AOR with a 600 PSI steam plant. Richard Dangel was bom in New York City. He received his Bachelor's degree from the Sloan School of Industrial Management of the Massachusetts Institute of Technology in 1955. He has also completed graduate work for a Masters in Engineering Administration at George Washington University. Since graduation he has spent 11 years in private industry with companies in the DOD engineering research

The Ship Energy Conservation Assist Team (SECAT) program was initiated in Fiscal Year (FY) 82 by the Naval Sea systems Command (NAVSEA) to demonstrate and introduce individual Ship Commands to known energy conserving techniques without adding equipment complexity or additional maintenance burden. The principal objective is to provide each ship with an energy consumption, coupled with recommended energy conservation strategies. The technique involves both in-port and underway monitoring and introduction of energy efficient machinery plant alignments, fuel consumption curve generation, and most efficient speed curves. The program has completed visits on six combatants and enjoys the support of both the Commander, Naval Surface Forces, U.S. Atlantic Fleet (COMNAVSURFLANT) and the Commander-in-Chief, U.S. Atlantic Fleet (CINCLANT). Plans are to perform SECAT on additional DDG 2 and FF 1052/1078 Class ships and initiate SECAT on additional ship types in FY 83.

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NAVAL SHIP DESIGN - EVOLUTION OR REVOLUTION

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NAVAL ENGINEERS JOURNAL 1988年第3期100卷 40-52页

作者： TIBBITTS, BF KEANE, RG RIGGINS, RJ Captain Barry Tibbitts USN: was graduated from the U.S. Naval Academy in 1956 and subsequently served as a gunnery division officer in an attack aircraft carrier and as gunnery officer operations officer and chief engineer in two diesel submarines. He attended MIT from 1962–1965 earning a master of science in mechanical engineering and a naval engineers degree. Early assignments as an engineering duty officer included SRF Yokosuka CINCPACFLT staff and SupShip Pascagoula. From 1976 to 1987 he served in a variety of senior ship design assignments: CVV ship design manager director NAVSEC Hull and Ship Design Divisions director NavSea Ship Design Management and Integration Office commander David Taylor Naval Ship R&D Center and director NavSea Ship Design Group. Recently retired but recalled to active duty he is the professor of naval construction and engineering at MIT. He has received seven personal decorations including two Legion of Merit awards. Robert G. Keane Jr.:is currently the deputy director of the NavSea Ship Design Group. He has been employed by NavSea and its predecessor organizations for over twenty years. He is a graduate of The Johns Hopkins University from which he received his B.E.S. degree in mechanical engineering in 1962. He received his M.E. degree in mechanical engineering in 1967 from Stevens Institute of Technology and in 1970 his M.S.E. degree in naval architecture and marine engineering from the University of Michigan. Mr. Keane held increasingly responsible design positions involving ship arrangements hull equipment hull form and hydrodynamic performance before being selected in 1981 for the Senior Executive Service to be director of the Naval Architecture Subgroup. Following an assignment at the David Taylor Research Center as assistant for transition of ship engineering technology he served as director of the Ship Survivability Subgroup until assuming his current position in 1985. He is an active member of ASNE SNAME and ASE. Robert Riggins:received a B.S. in mechanical

Some fairly radical changes to the naval ship design process occurred during the 1970s. The decade of the 80s has also witnessed a steady stream of changes. One of the most significant was the establishment of the Ship Characteristics Improvement Board (SCIB) in the Office of the Chief of Naval Operations (OpNav), and the resulting influence on the dialog between the military requirements decision makers and the Navy's ship designers. Other changes have occurred for which the impacts are less clear. These include establishment of the chief engineer of the Navy (ChEng) position, creation of the Space and Naval Warfare systems Command (SpaWar) and OpNav's “Revolution at Sea” initiative. This paper will describe and discuss these and other changes, and comment on the resultant impact. The authors will attempt to present a global view of the total pattern of changes and try to discern if we are on a path of revolution, or merely normal evolution.

关键词： NAVAL VESSELS

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Grasping and Attached Mode in Human-Computer Interaction in the Study of Mouse Substitution

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Journal of Physics: Conference Series 2019年第1期1196卷

作者： R B Widodo R M Quita S Amrizal R S Gunawan C Wada A Ardiansyah I Sutrisno M B Rahmat A Z Arfianto C R Handoko A D Santoso A W B Santosa V Y P Ardhana E Setiawan Informatics Engineering Study Program Ma Chung University Malang 65151 Indonesia Department of Mathematics Faculty of Science National Central University Taoyuan City 32001 Taiwan Graduate School of Life Science and Systems Engineering Kyushu Institute of Technology Wakamatsu Fukuoka 808-0196 Japan Politeknik Pelayaran Surabaya Gunung Anyar 60294 Surabaya Indonesia Department of Marine Electrical Engineering Politeknik Perkapalan Negeri Surabaya Sukolilo Surabaya 60111 Indonesia Departemen Teknik Perkapalan Fakultas Teknik Universitas Diponegoro Semarang 50275 Indonesia Universitas Qamarul Huda Badaruddin Bagu Central Lombok Indonesia

Some disabilities caused by sensory malfunction, accident, or congenital disorder could cause people difficulty in grasping the computer mouse. A well-known substitute uses an inertial sensor to monitor the body's orientation. This paper evaluates the efficiency and effectiveness of different methods of holding the sensor. There are two modes of holding the sensor, the grasping mode and the attached mode; we also evaluate a mouse as a baseline. The attached mode works by placing the sensor on the back of user's hand. The quantitative and qualitative evaluation procedure is based on ISO/TS 9241 part 411: Ergonomics of human-system interaction standard. The test consists of four levels of difficulty and indicates that the throughput and task completion times were not statistically different between grasping and attached mode. We also found that grasping mode and attached mode did not show significantly statistical differences in comfort and fatigue based on the questionnaires. The results also suggest that the orientation of the hand used in grasping and attached modes is suitable only for lower-impact computer use.

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