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RETROFITTING OF BULBOUS BOWS ON UNITED-STATES NAVY AUXILIARY AND AMPHIBIOUS WARSHIPS

NAVAL ENGINEERS JOURNAL 1984年第6期96卷 40-51页

作者： CHUN, SK HOUGH, JJ ENGLE, AH FUNG, SC Stephen K. Chunis a graduate of the Maritime College of the State University of New York class of 1981 from which he received a B.E. degree in naval architecture and his license as a Third Assistant Engineer from the U.S. Coast Guard. Since graduation he has worked for the U.S. Navy as a naval architect with the Hull Form and Hydrodynamics Performance Division (SEA 55W3) of the Naval Sea Systems Command. Currently he is the task leader for hydrodynamic design for the DDG-51. He is also responsible for bulbous bow and appendage design for surf ace ships. Mr. Chun is a member of ASNE SNAME and ASE. Jeffrey J. Hough:is currently a naval architect with the Hull Form and Hydrodynamic Performance Division (SEA 55VV3) of the Naval Sea Systems Command (NA VSEA). In his current capacity he is a member of the Surface Ship Hydrodynamics Branch and is the divisional coordinator for computer supported design (CSD) technical director for the hull form design system (HFDS) Hull Engineering Group (SEA 55) assistant coordinator for CSD SEA 55 CSD coordinator for the DDG-51 contract design and SEA 55W3 project engineer for aircraft carrier/aviation support ship hydrodynamics. Mr. Hough received his B.S.E. degree in naval architecture and marine engineering in 1978 and his M.S.E. degree in naval architecture and marine engineering in 1979 from the University of Michigan. He began his career with the U.S. Navy in 1979 as an Engineer-in-Training in the Ship Design and Integration Directorate of NAVSEA. Prior to his current assignment Mr. Hough was the technical director responsible for the hull form and hydrodynamics energy conservation program and technical specialist for design practices for resistance and powering margins and hull form geometry. A member of ASNE since 1979 Mr. Hough is also a member of SNAME ASE and the U.S. Naval Institute. Allen H. Engleis a naval architect with the Hull Form Design and Performance Division of the Naval Sea Systems Command. He received his B.S. degree in engineering science from th

To meet energy conservation goals of the U.S. Navy, its attention has been focused on ways to reduce individual ship total resistance and powering requirements. One possible method of improving ship powering characteristics is by modifying existing individual ship hulls with the addition of bulbous bows. This paper will identify the merits of retrofitting bow bulbs on selected U.S. Navy auxiliary and amphibious warfare ships. A procedure for performing a cost-benefit analysis will be shown for candidate ship classes. An example of this technique for an amphibious warfare ship will also be provided. A brief discussion of future methods to be used for bulbous bow design such as application of systematic model test data and numerical hydrodynamic techniques will be given.

关键词： NAVAL VESSELS

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TOI-3493 b: A planet with a Neptune-like density transiting a bright G0-type star

arXiv

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arXiv 2025年

作者： Chaturvedi, P. Goffo, E. Gandolfi, D. Persson, C.M. Hatzes, A.P. Nowak, G. Bonfanti, A. Bieryla, A. Cochran, W.D. Collins, K.A. Fajardo-Acosta, S.B. Howell, S.B. Jenkins, J.M. Korth, J. Livingston, J. Pallé, E. Quinn, S.N. Schwarz, R.P. Seager, S. Shporer, A. Stassun, K.G. Striegel, S. Van Eylen, V. Watkins, C.N. Winn, J.N. Ziegler, C. Thüringer Landessternwarte Tautenburg Sternwarte 5 Tautenburg07778 Germany Department of Astronomy and Astrophysics Tata Institute of Fundamental Research Mumbai400005 India Dipartimento di Fisica Università degli Studi di Torino via Pietro Giuria 1 TorinoI-10125 Italy Department of Space Earth and Environment Chalmers University of Technology Onsala Space Observatory Onsala43992 Sweden Institute of Astronomy Faculty of Physics Astronomy and Informatics Nicolaus Copernicus University Grudziądzka 5 Toruń87-100 Poland Space Research Institute Austrian Academy of Sciences Schmiedlstrasse 6 GrazA-8042 Austria Center for Astrophysics | Harvard & Smithsonian 60 Garden Street CambridgeMA02138 United States McDonald Observatory The University of Texas AustinTX United States Center for Planetary Systems Habitability The University of Texas AustinTX United States Caltech IPAC Mail Code 100-22 PasadenaCA91125 United States NASA Ames Research Center Moffett Field CA94035 United States Lund Observatory Division of Astrophysics Department of Physics Lund University Box 118 Lund22100 Sweden Astrobiology Center 2-21-1 Osawa Mitaka Tokyo181-8588 Japan National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Astronomical Science Program Graduate University for Advanced Studies SOKENDAI 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Calle Vía Láctea s/n Tenerife La Laguna38205 Spain Tenerife La Laguna38206 Spain Department of Physics Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA02139 United States Department of Earth Atmospheric and Planetary Sciences Massachusetts Institute of Technology CambridgeMA02139 United States Department of Aeronautics and Astronautics MIT 77 Massachusetts Avenue CambridgeMA02139 United States Department of Physics and Astronomy Vanderbilt University NashvilleTN37235 United States SETI Institute Mountain ViewCA94043 U

We report the discovery of TOI-3493 b, a sub-Neptune-sized planet on an 8.15-d orbit transiting the bright (V=9.3) G0 star HD 119355 (aka TIC 203377303) initially identified by NASA’s TESS space mission. With the aim of confirming the planetary nature of the transit signal detected by TESS and determining the mass of the planet, we performed an intensive Doppler campaign with the HARPS spectrograph, collecting radial velocity measurements. We found that TOI-3493 b lies in a nearly circular orbit and has a mass of 9.0 ± 1.2 M and a radius of 3.22 ± 0.08 R, implying a bulk density of 1.47+0.23-0.22g cm−3, consistent with a composition comprising a small solid core surrounded by a thick H/He-dominated atmosphere. © 2025, CC BY.

关键词： Earth atmosphere

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Energy-Based Evaluations on Eucalyptus Biomass Production

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International Journal of Forestry Research 2012年第1期2012卷

作者： Thiago L. Romanelli Marcos Milan Rafael Cesar Tieppo College of Agriculture “Luiz de Queiroz” (ESALQ) University of Sao Paulo (USP) Avenida Padua Dias 11 C.P.9 13418-900 Piracicaba SP Brazilesalq.usp.br Graduate Program in Engineering of Agricultural Systems College of Agriculture “Luiz de Queiroz” (ESALQ) University of Sao Paulo (USP) Avenida Padua Dias 11 C.P.9 13418-900 Piracicaba SP Brazilesalq.usp.br

Dependence on finite resources brings economic, social, and environmental concerns. Planted forests are a biomass alternative to the exploitation of natural forests. In the exploitation of the planted forests, planning and management are key to achieve success, so in forestry operations, both economic and noneconomic factors must be considered. This study aimed to compare eucalyptus biomass production through energy embodiment of anthropogenic inputs and resource embodiment including environmental contribution (emergy) for the commercial forest in the Sao Paulo, Brazil. Energy analyses and emergy synthesis were accomplished for the eucalyptus production cycles. It was determined that emergy synthesis of eucalyptus production and sensibility analysis for three scenarios to adjust soil acidity (lime, ash, and sludge). For both, energy analysis and emergy synthesis, harvesting presented the highest input demand. Results show the differences between energy analysis and emergy synthesis are in the conceptual underpinnings and accounting procedures. Both evaluations present similar trends and differ in the magnitude of the participation of an input due to its origin. For instance, inputs extracted from ores, which represent environmental contribution, are more relevant for emergy synthesis. On the other hand, inputs from industrial processes are more important for energy analysis.

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Emergence of Single- versus Multi-State Allostery

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PRX Life 2023年第2期1卷 023004-023004页

作者： Eric Rouviere Rama Ranganathan Olivier Rivoire Center for Physics of Evolving Systems Department of Biochemistry & Molecular Biology University of Chicago Chicago Illinois 60637 USA Graduate Program in Biophysical Sciences University of Chicago Chicago Illinois 60637 USA The Pritzker School for Molecular Engineering University of Chicago Chicago Illinois 60637 USA Center for Interdisciplinary Research in Biology (CIRB) Collège de France CNRS INSERM Université PSL Paris France Gulliver UMR CNRS 7083 ESPCI-Paris Université PSL Paris France

Several physical mechanisms have been proposed to explain allostery in proteins. They differ by the number of internal states that they assume a protein to occupy, leaving open the question of what controls the emergence of these distinct physical forms of allostery. Here, we analyze a simplified model of protein allostery under a range of physical and evolutionary constraints. We find that a continuum of mechanisms between two archetypes emerges through evolution. In one limit, a single-state mechanism exists where ligand binding induces a displacement along a single normal mode, and in the other limit, a multi-state mechanism exists where ligand binding induces a switch across an energy barrier to a different stable state. Importantly, whenever the two mechanisms are possible, the multi-state mechanism confers a stronger allosteric effect and thus a selective advantage. This work defines the essential constraints that distinguish single- and multi-state allostery and sets the stage for a physical theory of its evolutionary origins.

关键词： Biomolecular structure Molecular evolution Protein dynamics, structure & function Proteins

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CIRCULAR OVERMODED WAVE-GUIDE FOR SHIPBOARD USE

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NAVAL ENGINEERS JOURNAL 1993年第2期105卷 39-52页

作者： HUTING, WA WARREN, JW GARNER, PN KRILL, JA William A. Huting:received the B.S.E. degree in electrical engineering from Duke University in 1981 the M.S.E.E. degree from the Georgia Institute of Technology in 1982 and the Ph.D. degree in electrical engineering (electrophysics) from the University of Maryland in 1989. From September 1981 to December 1983 he was a graduate teaching assistant with Georgia Tech. Since January 1984 he has been with The Johns Hopkins University Applied Physics Laboratory where he has principally been involved with the development of circular overmoded waveguides and tapered waveguide transitions for use in naval radar systems. Dr. Huting is a member of the Institute of Electrical and Electronics Engineers. Jeffery W. Warren:received a B.S. degree in 1982 and an M.S. degree in 1984 both in electrical engineering from the University of South Carolina. His thesis research evaluated electro-optical measurements of surface charging of insulators in low-frequency fields. He joined The Johns Hopkins University Applied Physics Laboratory in 1984. Mr. Warren's activities include development and testing of electro-optical systems and the development of high-power low-loss overmoded waveguides. Mr. Warren is a member of the Institute of Electrical and Electronics Engineers. Paul N. Garner: Jr. received the B.S. degree in mathematics and the B.S. degree in mechanical engineering from the University of Maryland in 1973 and 1980 respectively and the M.B.A. degree from the Florida Institute of Technology in 1984. Since 1987 he has been involved with the Cooperative Engagement Capability Program as the lead mechanical engineer and since 1990 he has been with The Johns Hopkins University Applied Physics Laboratory where he is now a member of the Senior Professional Staff. Jerry A. Krill:received the B.S.E.E. and M.S.E.E. degrees from Michigan State University in 1973 and 1974 respectively and a Ph.D. in electrical engineering (electrophysics) from the University of Maryland in 1978. From 1973 to the present he has been with The Johns

Several future Navy combat systems under development require efficient delivery of high power microwave energy from remote transmitters to array antennas. To achieve this requirement, a family of microwave components has been developed and tested. Progress is described in the design and testing of an overmoded circular TE01 mode waveguide applicable to special shipboard needs. Because such a waveguide had originally been developed for low power millimeter band trunkline communications between cities, new theoretical, design, and fabrication techniques had to be developed to meet our specific performance requirements. Moreover, in order to fulfill the combat system requirements, the waveguide would have to withstand harsh military requirements. Over several years the obstacles to the application of overmoded technology to Navy combat systems have been systematically eliminated. The effort has resulted in the invention of several new components, the development and validation of a new computer aided design package, and the implementation of new microwave measurement techniques. The first application of an overmoded waveguide to a combat system element was recently achieved in the successful demonstration of the prototype Cooperative Engagement Capability, and steps toward a production military version of the waveguide have been initiated.

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THE FFG–7 GUIDED MISSLE FRIGATE program– MODEL FOR THE FUTURE?

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Naval Engineers Journal 1978年第3期90卷 93-105页

作者： BEECHER, JOHN D. DiTRAPANI, ANTHONY R. Captain John D. Beecher USN:is the Project Manager Guided Missile Frigate Ship Acquisition Project. He holds a BS degree in Naval Science from the U. S. Naval Academy a BS degree in Electrical Engineering from the U. S. Navy Postgraduate School and a MS degree in Aeronautics and Astronautics from MIT. He is a qualified Surface Warfare Officer who served for seventeen years in the unrestricted line. Captain Beecher's military decorations include the Meritorious Service Medal with Star in lieu of Second Award. Mr. Anthony R. DiTrapani:is the Deputy Project Manager of the Guided Missile Frigate Ship Acquisition Project. He received his BS degree in Mechanical Engineering from the University of Wisconsin in 1958. He began his engineering career in the Navy's Bureau of Ships Steam Turbine and Gear Branch. specializing in steam turbine systems for nuclear submarines. In 1962 after completing graduate work at The George Washington University and a Navy–sponsored Electronics Training Program he joined the SQS–26 Sonar Project and served as Head of the Special Projects Section and subsequently the Test and Analysis Section until 1967. In 1967 he was selected to head the ASW Branch and later the Technical Management Plans Division for the DD–963 Ship Acquisition Project. Naval Sea Systems Command until 1971 when he was assigned to the FFG Project.

Late in 1970, Admiral E. R. Zumwalt, Chief of Naval Operations, directed that study begin towards development of a new class of ocean escort, now known as the FFG 7 (Oliver Hazard Perry) Class, to take over some of the duties of the Navy's World War II destroyers as these 25 year old ships are retired from the active Fleet. At the same time, the Department of Defense was significantly revising its basic policies for the development and acquisition of major weapons systems, and the FFG became the Navy's first major ship class acquisition under these new policies. These new policies, as announced in DOD Directive 5000.1, along with the program constraints imposed by the CNO, required the development of a philosophy and approach towards design, test and evaluation and acquisition which was significantly different from previous ship procurements. This paper summarizes the overall acquisition, T&E and logistic support plans for the FFG 7 Class as they were developed and implemented to meet these needs and constraints, discusses the ship trial results, and provides a commentary regarding the effectiveness of the approach and future applicability. © 1978 American Society of Naval Engineers

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Development and evaluation of a hospital-wide healthcare-associated surgical site infection detection algorithm

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Journal of Microbiology, Immunology and Infection 2015年第2期48卷 S43-S43页

作者： Yi-Ju Tseng Bo-Chiang Huang Hui-Chi Lin Ming-Yuan Chen Rung-Ji Shang Wang-Huei Sheng Yee-Chun Chen Feipei Lai Shan-Chwen Chang Children's Hospital Informatics Program Boston Children's Hospital Boston MA USA Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taiwan Center for Infection Control National Taiwan University Hospital (NTUH) Taiwan Information Systems Office NTUH Taipei Taiwan Department of Internal Medicine NTUH and College of Medicine Taiwan National Institute of Infectious Diseases and Vaccinology National Health Research Institutes Taiwan Department of Computer Science and Information Engineering National Taiwan University Taiwan

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Ten quick tips for deep learning in biology

arXiv

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arXiv 2021年

作者： Lee, Benjamin D. Gitter, Anthony Greene, Casey S. Raschka, Sebastian Maguire, Finlay Titus, Alexander J. Kessler, Michael D. Lee, Alexandra J. Chevrette, Marc G. Stewart, Paul Allen Britto-Borges, Thiago Cofer, Evan M. Yu, Kun-Hsing Carmona, Juan Jose Fertig, Elana J. Kalinin, Alexandr A. Signal, Beth Lengerich, Benjamin J. Triche, Timothy J. Boca, Simina M. In-Q-Tel Labs School of Engineering and Applied Sciences Harvard University Department of Genetics Harvard Medical School United States Department of Biostatistics and Medical Informatics University of Wisconsin-Madison MadisonWI United States Morgridge Institute for Research MadisonWI United States Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Biochemistry and Molecular Genetics University of Colorado School of Medicine AuroraCO United States Center for Health AI University of Colorado School of Medicine AuroraCO United States Department of Statistics University of Wisconsin Madison United States Faculty of Computer Science Dalhousie University Canada University of New Hampshire Bioeconomy.XYZ United States Department of Oncology Johns Hopkins University United States Institute for Genome Sciences University of Maryland School of Medicine United States Genomics and Computational Biology Graduate Program University of Pennsylvania United States Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania United States Wisconsin Institute for Discovery Department of Plant Pathology University of Wisconsin-Madison United States Department of Biostatistics and Bioinformatics Moffitt Cancer Center TampaFL United States Section of Bioinformatics and Systems Cardiology Klaus Tschira Institute for Integrative Computational Cardiology University Hospital Heidelberg Germany University Hospital Heidelberg Germany Lewis-Sigler Institute for Integrative Genomics Princeton University PrincetonNJ United States Graduate Program in Quantitative and Computational Biology Princeton University PrincetonNJ United States Department of Biomedical Informatics Harvard Medical School United States Department of Pathology Brigham and Women's Hospital United States Philips Healthcare CambridgeMA United States Philips Research

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive modeling. Artificial neural networks are a particular class of machine learning algorithms and models that evolved into what is now described as deep learning. Given the computational advances made in the last decade, deep learning can now be applied to massive data sets and in innumerable contexts. Therefore, deep learning has become its own subfield of machine learning. In the context of biological research, it has been increasingly used to derive novel insights from high-dimensional biological data. To make the biological applications of deep learning more accessible to scientists who have some experience with machine learning, we solicited input from a community of researchers with varied biological and deep learning interests. These individuals collaboratively contributed to this manuscript's writing using the GitHub version control platform and the Manubot manuscript generation toolset. The goal was to articulate a practical, accessible, and concise set of guidelines and suggestions to follow when using deep learning. In the course of our discussions, several themes became clear: the importance of understanding and applying machine learning fundamentals as a baseline for utilizing deep learning, the necessity for extensive model comparisons with careful evaluation, and the need for critical thought in interpreting results generated by deep learning, among others. © 2021, CC BY.

关键词： Learning algorithms

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Label-free GR5 DNAzyme-based colorimetric sensing for lead ions (Pb2+) detection

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AIP Conference Proceedings 2023年第1期2720卷

作者： Muhammad Nur Hasan Patsamon Rijiravanich Werasak Surareungchai Nanoscience and Nanotechnology Graduate Program Faculty of Science King Mongkut’s University of Technology Thonburi Bang Mod Thung Khru Bangkok 10140 Thailand Biosciences and Systems Biology Research Team National Center for Genetic Engineering and Biotechnology National Sciences and Technology Development Agency at King Mongkut’s University of Technology Thonburi Bang Khun Thian Bangkok 10150 Thailand School of Bioresources and Technology King Mongkut’s University of Technology Thonburi Bang Khun Thian Bangkok 10150 Thailand

Lead (Pb2+) contamination in blood can trigger the developmental of disabilities in children and some serious problems of chronic illnesses. In this work, a simple label-free GR5 DNAzyme and gold nanoparticles were applied in a colorimetric assay for Pb2+ detection. Using this method, the reaction and cleaving process between DNAzyme and lead were perfect. The experiment was successfully tested for the detection of Pb2+ in the buffer. The visual detection limit of this colorimetric assay obtained was 10 nM. The biosensor showed excellent specificity for Pb2+ compared to other metal ions.

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A NOTE ON ANTI-SHIP MISSILES AND FUTURE SHIP DESIGN

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NAVAL ENGINEERS JOURNAL 1980年第4期92卷 84-86页

作者： RUHE, WJ USN (RET.) THE AUTHOR: is a graduate of the U.S. Naval Academy Class of 1939 who served in Submarines during World War II and much of his naval career. Later he commanded Destroyers and Missile-Armed Destroyer Units his major command being the TERRIER-Armed Guided Missile Cruiser USS Topeka. Much of his shore duty career involved conceptual planning for new Navy systems as well as operational research involving sea wars of the future and he directed the study effort for the ocean wars in the first General Purpose Forces Studies conducted by the Joint Chiefs of Staff. On retirement in 1967 he joined the Staff of the President's Commission on Ocean Engineering and Research and upon completing his Commission work joined General Dynamics' Corporate Director of Marine Program Development presently serving in General Dynamics' Washington Office as Manager of Warfare Analysis and Energy Programs. His numerous articles in national magazines stress the great changes which he feels we must be aware of if we are to meet the challenge which the missile-dependent Soviet Navy now poses.

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