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Communications engineering 2024年第1期3卷 1-20页

作者： Amereh, Meitham Shojaei, Shahla Seyfoori, Amir Walsh, Tavia Dogra, Prashant Cristini, Vittorio Nadler, Ben Akbari, Mohsen Department of Mechanical Engineering University of Victoria 3800 Finnerty Road Victoria V8P 5C2 BC Canada Laboratory for Innovations in MicroEngineering (LiME) University of Victoria 3800 Finnerty Road Victoria V8P 5C2 BC Canada Centre for Advanced Materials and Related Technologies (CAMTEC) University of Victoria 3800 Finnerty Road Victoria V8P 5C2 BC Canada Department of Anatomy and Cell Sciences University of Manitoba 66 Chancellors Cir Winnipeg R3B 2E9 MB Canada Mathematics in Medicine Program Department of Medicine Houston Methodist Research Institute 6670 Bertner Ave. Houston 77030 TX United States Department of Physiology and Biophysics Weill Cornell Medical College 1300 York Ave. New York 10065 NY United States Neal Cancer Center Houston Methodist Research Institute 6670 Bertner Ave. Houston 77030 TX United States Department of Imaging Physics University of Texas M.D. Anderson Cancer Center 1515 Holcombe Blvd Houston 77030 TX United States Physiology Biophysics and Systems Biology Program Graduate School of Medical Sciences Weill Cornell Medicine 1300 York Ave. New York 10065 NY United States School of Biomedical Engineering University of British Columbia 2329 West Mall Vancouver V6T 1Z4 BC Canada

Non-physiological levels of oxygen and nutrients within the tumors result in heterogeneous cell populations that exhibit distinct necrotic, hypoxic, and proliferative zones. Among these zonal cellular properties, metabolic rates strongly affect the overall growth and invasion of tumors. Here, we report on a hybrid discrete-continuum (HDC) mathematical framework that uses metabolic data from a biomimetic two-dimensional (2D) in-vitro cancer model to predict three-dimensional (3D) behaviour of in-vitro human glioblastoma (hGB). The mathematical model integrates modules of continuum, discrete, and neurons. Results indicated that the HDC model is capable of quantitatively predicting growth, invasion length, and the asymmetric finger-type invasion pattern in in-vitro hGB tumors. Additionally, the model could predict the reduction in invasion length of hGB tumoroids in response to temozolomide (TMZ). This model has the potential to incorporate additional modules, including immune cells and signaling pathways governing cancer/immune cell interactions, and can be used to investigate targeted therapies. © The Author(s) 2024.

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THE FFG 7 CLASS DESIGN IMPACT BY INSURV TRIALS

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NAVAL ENGINEERS JOURNAL 1982年第2期94卷 87-100页

作者： WOODRUFF, RB The authorgraduated from the U.S. Naval Academy with distinction in 1964. He served initially in theUSS Davis (DD-937)as Main Propulsion Assistant attended the Naval Destroyer School and then was a member of the Pre-Commissioning Crew and Engineer Officer in theUSS Julius A. Furer (DEG-6).Selected as an Engineering Duty Officer (ED) in 1968 he had a tour in the Maintenance Department Staff of Commander Cruisr-Destroyer Force U.S. Atlantic Fleet at Newport R.I. after which he attended Massachusetts Institute of Technology for graduate studies which culminated in his receiving his M.S. degree in Mechanical Engineering and his degree of Ocean Engineer in 1972. Following graduation he was assigned to the Boston Naval Shipyard followed by two years in theUSS Puget Sound (AD-38)as Repair Officer after which he was ordered to the Norfolk Naval Shipyard as the Production Engineering Officer. Currently he is on duty in the Naval Sea Systems Command (PMS 399) where he is the Trials Officer and Hull Technical Director for theOliver Hazard Perry (FFG-7)Class Acquisition Program. Cdr. Woodruff is a qualified Surface Warfare Officer and among his military decorations holds the Naval Achievement Medal and the Vietnamese Meritorious Unit Citation Gallantry Cross. In addition to ASNE which he joined in 1967 he is a member of the U.S. Naval Institute. Two previous papers on Naval Shipyard Production presented at ASNE Day 1978 and 1979 were published in the Naval Engineers Journal Vol. 90 No. 2 (April 1978) and Vol. 91 No. 2 (April 1979). A paper on the Management of Surface Ship Maintenance was published in theNaval Engineers JournalDecember 1980.

This paper describes the impact made on the OLIVER HAZARD PERRY (FFG 7) Class design after numerous trials by the President, Board of Inspection and Survey and his Staff. In the early 1970s, faced with a Fleet of World War II Destroyers, the Navy embarked on a program to build large numbers of Frigates to perform an Ocean Escort role. This ship had three major design constraints placed on it by Chief of Naval Operations (CNO): fixed meaning, fixed displacement, and fixed cost or “designed to cost.” The purpose of this paper is to pass on some “lessons learned.” The acid test of any ship design is how well it does with the Fleet in regard to performance and reliability. How well has the “design-constrained” FFG-7 fared with 20 plus ship trials under its belt? Very well in some areas; not so well in others. Examples of the good aspects of this ship design (LM 2500 and main propulsion train, Standard Option Equipment, et cetera) as well as those which must be considered poor will be addressed. Some examples of the latter are the “breezeway” cargo doors, ship's service diesel generators, MK 92 Combat systems, decontamination stations, and topside corrosion control. In many cases INSURV caused design changes to be made that were sorely needed; in other cases, changes were made (or not made) over issues that had little or no impact on making this ship more ready for war. A brief examination of the Naval Sea systems Command (NAVSEA) surface ship design policies is made from the point of view of the Trials Officer (the Author) who rode most of the trials with PRESINSURV. Some of the issues addressed: •Improved NAVSEA corporate memory between ship designs. •Longer Acceptance Trial for Lead Ship. •Early deployment of Lead Ship without TECHREPS. •Improved NAVSEA/INSURV/CNO communication on Trial/Technical Issues and insertion of INSURV early into the design process. •Need for NAVSEA to stand up and say “no” to costly design changes that do little to make for a better warship.

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THE MANAGEMENT OF SURFACE SHIP MAINTENANCE

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NAVAL ENGINEERS JOURNAL 1980年第6期92卷 71-83页

作者： WOODRUFF, RB USN THE AUTHORgraduated from the U.S. Naval Academy with distinction in 1964. He served initially in theUSS Davis (DD-937)as Main Propulsion Assistant attended the Naval Destroyer School. and then was a member of the Pre-Commissioning Crew and Engineer Officer in theUSS Julius A. Furer (DEG-6).Selected as an Engineering Duty Officer (ED) in 1968. he had a tour in the Maintenance Department Staff of Commander Cruiser-Destroyer Force U.S. Atlantic Fleet at Newport. R.I. after which he attended Massachusetts Institute of Technology for graduate studies which culminated in his receiving his M.S. degree in Mechanical Engineering and his degree of Ocean Engineer in 1972. Following graduation he was assigned to the Boston Naval Shipyard followed by two years in theUSS Puget Sound (AD-38) asRepair Officer after which he was ordered to the Norfolk Naval Shipyard as the Production Engineering Officer. Currently he is on duty in the Naval Sea Systems Command (PMS 399) where he is the Trials Officer and Deputy Hull Technical Director for the OLIVER HAZARD PERRY (FFG 7) Class Acquisition Program. Cdr. Woodruff is a qualified Surface Warfare Officer. and among his military decorations holds the Naval Achievement Medal and the Vietnamese Meritorious Unit Citation Gallantry Cross. In addition to ASNE which he joined in 1967. he is a member of SNAME and the U.S. Naval Institute. and his two previous papers on Naval Shipyard Production presented at ASNE Day 1978 and 1979 were published in theNaval Engineers JournalVol. 90 No. 2 (April 1978) and Vol. 91. No. 2 (April 1979).

The purpose of the paper is to address the current dilemma facing the Surface Ship Navy as it approaches the twenty-first century. The basic underlying thesis is that the Maintenance Community has lost sight of the goal it must have: to support the Commanding Officer of a ship to get his ship from point A to point B with its weapons system ready. To do this, three basic things must occur: 1) the ship must be capable of getting underway and steaming (i.e., turn the screw); 2) the ship must have its weapons systems working and “up” in all respects (i.e., fight the ship); and 3) the Crew must be prepared (i.e., have sufficient training). It Is submitted that we have lost sight of this fact. There remains an inordinate amount of concern over appearance (external and internal), habitability, plaques, inspections, and various human factors programs, and funds may be spent in there areas when the main machinery plant and missile systems are “down.” A recent example is the effort to remove every speck of wood from all Navy ships including picture frames. Training is addressed also as the third key element missing, particularly in the main machinery spaces. A brief examination is made of the ship cycle as it gas into the maintenance mode, i.e., delivery plus one to two years. A comparison is made with the basic Submarine Force approach to this problem and when the Surface Community may take a page out of the Submarine Force book. An addressed are: 1) Current Ship's Maintenance Project (CSMP); 2) Planned Maintenance System (PMS); 3) Pre-Overhaul Test and Inspection (POT&I); 4) Long lead time SHIPALT material, 5) Intermediate Maintenance Activity (IMA) role (Tenders and SIMAS); and 6) Shipyard role and facilities.

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OpenMM 8: Molecular Dynamics Simulation with Machine Learning Potentials

arXiv

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arXiv 2023年

作者： Eastman, Peter Galvelis, Raimondas Peláez, Raúl P. Abreu, Charlles R.A. Farr, Stephen E. Gallicchio, Emilio Gorenko, Anton Henry, Michael M. Hu, Frank Huang, Jing Krämer, Andreas Michel, Julien Mitchell, Joshua A. Pande, Vijay S. Rodrigues, João P.G.L.M. Rodriguez-Guerra, Jaime Simmonett, Andrew C. Singh, Sukrit Swails, Jason Turner, Philip Wang, Yuanqing Zhang, Ivy Chodera, John D. De Fabritiis, Gianni Markland, Thomas E. Department of Chemistry Stanford University StanfordCA94305 United States Acellera Labs C Dr Trueta 183 Barcelona08005 Spain C Dr. Aiguader 88 Barcelona08003 Spain Chemical Engineering Department School of Chemistry Federal University of Rio de Janeiro Rio de Janeiro68542 Brazil Redesign Science Inc. 180 Varick St. New YorkNY10014 United States EaStCHEM School of Chemistry University of Edinburgh EH9 3FJ United Kingdom Department of Chemistry and Biochemistry Brooklyn College The City University of New York NY United States Ph.D. Program in Chemistry Ph.D. Program in Biochemistry The Graduate Center of the City University of New York New YorkNY United States Stream HPC Koningin Wilhelminaplein 1 - 40601 Amsterdam1062 HG Netherlands Computational and Systems Biology Program Sloan Kettering Institute Memorial Sloan Kettering Cancer Center New YorkNY10065 United States Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University 18 Shilongshan Road Zhejiang Hangzhou310024 China Department of Mathematics and Computer Science Freie Universität Berlin Arnimallee 12 Berlin14195 Germany The Open Force Field Initiative Open Molecular Software Foundation DavisCA95616 United States Andreessen Horowitz 2865 Sand Hill Rd Menlo ParkCA94025 United States Department of Structural Biology Stanford University StanfordCA94305 United States Charité Universitätsmedizin Berlin In silico Toxicology and Structural Bioinformatics Virchowweg 6 Berlin10117 Germany Laboratory of Computational Biology National Heart Lung and Blood Institute National Institutes of Health BethesdaMD20892 United States Entos Inc. 9310 Athena Circle La Jolla CA92037 United States College of Engineering Virginia Polytechnic Institute State University BlacksburgVA24061 United States Simons Center for Computational Physical Chemistry Center for Data Science New York University 24 Waverly Place New YorkNY10004 United States T

Machine learning plays an important and growing role in molecular simulation. The newest version of the OpenMM molecular dynamics toolkit introduces new features to support the use of machine learning potentials. Arbitrary PyTorch models can be added to a simulation and used to compute forces and energy. A higher-level interface allows users to easily model their molecules of interest with general purpose, pretrained potential functions. A collection of optimized CUDA kernels and custom PyTorch operations greatly improves the speed of simulations. We demonstrate these features on simulations of cyclin-dependent kinase 8 (CDK8) and the green fluorescent protein (GFP) chromophore in water. Taken together, these features make it practical to use machine learning to improve the accuracy of simulations at only a modest increase in cost. Copyright © 2023, The Authors. All rights reserved.

关键词： Machine learning

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RATIONALE FOR AN ADA SOFTWARE engineering ENVIRONMENT FOR NAVY MISSION CRITICAL APPLICATIONS

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NAVAL ENGINEERS JOURNAL 1984年第4期96卷 133-145页

作者： PAIGE, KK CONVERSE, RA USN LCdr. Kathleen K. Paige USN:graduated with a BA from the University of New Hampshire in 1970. She received her commission from Officer Candidate School in April 1971 and performed her first tour of duty with VFP-63 NAS Miramar. LCdr. Paige then received her MS from the Naval Post Graduate School in June 1976 and returned to San Diego to serve as Head Support Software Division at the Fleet Combat Direction System Support Activity. In May 1981 she reported to NA VSEA (PMS-408) where she served initially as Chairman of the NAVMAT Software Engineering Environment Working Group. She has been assigned as Deputy AN/UYK-43 Acquisition Manager since October 1981. LCdr. Paige was designated a fully qualified Engineering Duty Officer in December 1983. Robert A. Converse:is presently the Acquisition Manager for the Ada Language System/Navy (ALS/N) for the Naval Sea Systems Command Tactical Embedded Computer Resources Project. As such he is responsible for the definition and development of the ALS/N to be provided as a Navy standard computer programming system for Navy mission critical applications. Mr. Converse received a Bachelor of Science degree in Physics from Wheaton College Wheaton II. He spent fourteen years with the Naval Underwater Systems Center Newport Rhode Island during which time he designed and developed the Fortran compiler for the Navy Standard AN/UYK-7 computer. Also during that period he received a Master of Science degree in Computer Science from the University of Rhode Island. His thesis for that degree was entitled “Optimization Techniques for the NUSC Fortran Cross-Compiler”. Mr. Converse started his involvement with the Ada program in 1975 with the initial “Strawman” requirements review. Subsequently he was named as the Navy Ada Distinguished Reviewer and was intimately involved in the selection and refinement of the Ada language as it evolved to become ANSI/MIL-STD-1815A.

The U.S. Navy introduced the use of digital computers in mission critical applications over a quarter of a century ago. Today, virtually every system in the current and planned Navy inventory makes extensive use of computer technology. Computers embedded in mission critical Navy systems are integral to our strategic and tactical defense capabilities. Thus, the military power of the U.S. Navy is inextricably tied to the use of programmable digital computers. The computer program is the essential element that embodies the system “intelligence”. In addition, it provides the flexibility to respond to changing threats and requirements. However, this very flexibility and capability poses a host of difficulties hindering full realization of the advantages. This paper describes the lessons learned about computer program development over the past twenty five years and discusses a software engineering process that addresses these lessons. It then describes how Ada and its related Ada programming Support and Run-Time Environments foster this software engineering process to improve computer program productivity and achieve greater system reliability and adaptibility. Finally, the paper discusses how the use of Ada and its environments can enhance the interoperability and transferability of computer programs among Navy projects and significantly reduce overall life cycle costs for Navy mission critical computer programs.

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Historical growth of concept networks in Wikipedia

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Collective Intelligence 2022年第2期1卷 26339137221109839页

作者： Harang Ju Dale Zhou Ann S Blevins David M Lydon-Staley Judith Kaplan Julio R Tuma Dani S Bassett Neuroscience Graduate Group University of Pennsylvania Philadelphia PA USA Department of Bioengineering School of Engineering & Applied Science University of Pennsylvania Philadelphia PA USA Annenberg School for Communication University of Pennsylvania Philadelphia PA USA Department of History and Sociology of Science College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Integrated Studies Program College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Integrated Studies Program College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Department of Philosophy College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Department of Electrical & Systems Engineering School of Engineering & Applied Science University of Pennsylvania Philadelphia PA USA Department of Physics & Astronomy College of Arts & Sciences University of Pennsylvania Philadelphia PA USA Department of Neurology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Santa Fe Institute Santa Fe NM USA

Philosophers of science have long questioned how collective scientific knowledge grows. Although disparate answers have been posited, empirical validation has been challenging due to limitations in collecting and systematizing large historical records. Here, we introduce new methods to analyze scientific knowledge formulated as a growing network of articles on Wikipedia and their hyperlinks. We demonstrate that in Wikipedia, concept networks in subdisciplines of science do not grow by expanding from their central core to reach an ancillary periphery. Instead, science concept networks in Wikipedia grow by creating and filling knowledge gaps. Notably, the process of gap formation and closure may be valued by the scientific community, as evidenced by the fact that it produces discoveries that are more frequently awarded Nobel prizes than other processes. To determine whether and how the gap process is interrupted by paradigm shifts, we operationalize a paradigm as a particular subdivision of scientific concepts into network modules. Hence, paradigm shifts are reconfigurations of those modules. The approach allows us to identify a temporal signature in structural stability across scientific subjects in Wikipedia. In a network formulation of scientific discovery, our findings suggest that data-driven conditions underlying scientific breakthroughs depend as much on exploring uncharted gaps as on exploiting existing disciplines and support policies that encourage new interdisciplinary research.

关键词： science of science networks philosophy of science Wikipedia cavity

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THE AIR CUSHION VEHICLE EVALUATION AND POTENTIAL

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Naval Engineers Journal 1966年第3期78卷 421-442页

作者： CHAPLIN, JOHN B. The Author was educated in Britain at the Miles Aeronautical College receiving a Royal Aeronautical Society Graduate diploma in 1949. From 1949 to 1960 he was employed by the Saunders Roe Aircraft Company and held positions in aerodynamics and wind tunnel departments participating in the design of the “Princess” flying boats the SRA1 fighter flying boat and the SR53 rocket interceptor cooperating during the latter program with Royal Aircraft Establishment in the development of free-flight model spinning research techniques. In 1958 he was appointed head of the Wind Tunnel and Dynamic Research Department of Saunders Roe and was responsible for the original research evaluation and assessment of Cockerell's hovercraft proposals. He was responsible for the conceptual design of the SRN1 hovercraft the trials and development of that vehicle and the aerodynamic research of the SRN2 program. During the early trials of the SRN1 including the first crossing of the English channel he was a member of the flight crew. In 1960 he joined the Follard Division of the Hawker Siddeley Group as chief hovercraft development engineer taking part in a program to evaluate and exploit the overland possibilities of the ground effect machines. He was responsible for the design development and driving of several test vehicles including the GERM and a series of plenum cell pallets for the Army. During this period he was chairman of the British Hovercraft Operational Panel set up to aid the Air Registration Board and the Ministry of Transport. Mr. Chaplin joined Bell Aerosystems Company in March 1962 as Chief of Air Cushion Vehicle systems in Advanced Design. In this capacity he is responsible for designing and developing new ACV concepts. Noteworthy in this effort has been his design of a tri-cell type ACV. Mr. Chaplin was also responsible for the fabrication and testing of this machine now called the Caraboa. It is a two-place ACV designed for military and commercial utility use. Mr. Chaplin has also conducted a study and tes

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U.S. SHIPBUILDING: THE SEVENTIES IN RETROSPECT —THE PROSPECTS FOR THE EIGHTIES

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Naval Engineers Journal 1980年第4期92卷 25-38页

作者： FISHER, JAMES R. COADY, PHILIP USN Capt. James Ronald Fisher USN is a graduate of the U.S. Naval Academy. Class of 1958. has his M.A. degree in Management and is an Engineering Duty Officer (ED). He has served in a Destroyer and four Attack and Fleet Ballistic Missile Submarines as Training Officer of the Nuclear Propulsion Unit. West Milton N. Y. and at the Charleston Naval Shipyard where he also was the Chairman of the ASNE Charleston Section. He was ordered to the National Defense University from duty in the Industrial Management Directorate Naval Sea Systems Command (NAVSEA). and has just recently been reassigned to the Submarine Platform Directorate at NA VSEA. Cdr. Philip Coady USN is a graduate of Tufts University from which he received his A.B. degree in 1963 and also the Naval Postgraduate School. Monterey. Calif. from which he received his M.S. degree in 1972. His sea experience has been predominently in Destroyers. most recently as Executive Officer of the USS Claude V. Ricketts (DDG-S) and has had two tours in the Office of the Chief of Naval Operations (OP-090) his latest being that of Special Assistant for Financial Management to the Director of Navy Program Planning (OP-090). Currently he is under orders to assume command of the USS Conolly (DD-979).

This paper reviews the recent turbulent history of the U.S. Shipbuilding Industry, its present status, and its prospects for the decade ahead. The Authors suggest that current maritime policy and the trend of market f...

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The Significance of Certain Parameters in Buoyancy System Performance

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Naval Engineers Journal 1971年第4期83卷 75-81页

作者： HANSEN, O. RICHARD UHLER, DALE G. O. Richard Hansen obtained a BSCE from Colorado State University in 1950 and has participated in continuing educational courses at the University of Washington Wayne State University and the University of Michigan. He was employed at Puget Sound Naval Shipyard for five years as a Mechanical Engineer and Project leader in industrial gases and cryogenic O2. Producers for Shipboard Applications followed by seven years at Chrysler Corporation initially as a project engineer in the FBM program subsequently assigned to Mechanical Laboratory achieving Managing Engineer status of a department therein which contained the facilities group instrumentation group and an experimental machine shop. This was followed by employment at Westinghouse Astronuclear Laboratories as a senior engineer conducting studies in two phase liquid hydrogen flow in simulated NERVA cores. Following this he served two years of employment with the Lockheed Georgia Company conducting material studies in combined nuclear cryogenic environments at the NASA 60 megawatt test reactor located in Sandusky Ohio. Joined NAVSEC in 1966 as a mechanical engineer in the compressed air systems group and has been assigned to the Supervisor of Diving Salvage and Ocean Engineering conducting analysis and evaluation of compressed air and gas systems associated with diving and salvage operations. Dale G. Uhler received BSCE degree from Carnegie Institute of Technology in 1964. He spent two years as a construction engineer before entering graduate school at the University of Miami Florida where he received his MS degree in applied mechanics with a minor in Ocean Engineering in 1968. He is now employed as an Ocean Engineer in the office of the U. S. Navy Director of Diving Salvage and Ocean Engineering where he is the project manager for the Large Object Salvage System and related development programs and concurrently working toward his Ph. D. at Catholic University.

The advent of deep ocean technology has created a need of buoyancy at ever increasing depths. This paper concerns itself with two most widely used techniques for dewatering/deballasting, compressed air supplied by surface maintained compressors and high pressure gases contained in pressure vessels. The objective of the paper is to examine the effects on these two techniques of various parameters which, in the author's opinion, are often overlooked by design engineers. This results in a significant degradation of the system under actual operating conditions. The principal parameters involved are structural integrity, geometric properties, material properties and the variance with pressure of the real gas properties and sea water density. This paper is an attempt to appraise designers and users of the impact of the above considerations on proposed buoyancy systems. © 1971 American Society of Naval Engineers

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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