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arXiv 2019年

作者： Gasparin, Suelen Dutykh, Denys Mendes, Nathan LAMA UMR 5127 CNRS Université Savoie Mont Blanc Campus Scientifique F-73376 Le Bourget-du-Lac Cedex France and Thermal Systems Laboratory Mechanical Engineering Graduate Program Pontifical Catholic University of Paraná Rua Imaculada Conceição 1155 Curitiba – ParanáCEP: 80215-901 Brazil Univ. Grenoble Alpes Univ. Savoie Mont Blanc CNRS LAMA Chambéry73000 France LAMA UMR 5127 CNRS Université Savoie Mont Blanc Campus Scientifique Le Bourget-du-Lac CedexF-73376 France Thermal Systems Laboratory Mechanical Engineering Graduate Program Pontifical Catholic University of Paraná Rua Imaculada Conceição 1155 Curitiba – ParanáCEP: 80215-901 Brazil

This work presents an efficient numerical method based on spectral expansions for simulation of heat and moisture diffusive transfers through multilayered porous materials. Traditionally, by using the finite-difference approach, the problem is discretized in time and space domains (Method of lines) to obtain a large system of coupled Ordinary Differential Equations (ODEs), which is computationally expensive. To avoid such a cost, this paper proposes a reduced-order method that is faster and accurate, using a much smaller system of ODEs. To demonstrate the benefits of this approach, tree case studies are presented. The first one considers nonlinear heat and moisture transfer through one material layer. The second case – highly nonlinear – imposes a high moisture content gradient – simulating a rain like condition – over a two-layered domain, while the last one compares the numerical prediction against experimental data for validation purposes. Results show how the nonlinearities and the interface between materials are easily and naturally treated with the spectral reduced-order method. Concerning the reliability part, predictions show a good agreement with experimental results, which confirm robustness, calculation efficiency and high accuracy of the proposed approach for predicting the coupled heat and moisture transfer through porous materials. Copyright © 2019, The Authors. All rights reserved.

关键词： Porous materials

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Historical growth of concept networks in Wikipedia

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Collective Intelligence 2022年第2期1卷 26339137221109839页

作者： Harang Ju Dale Zhou Ann S Blevins David M Lydon-Staley Judith Kaplan Julio R Tuma Dani S Bassett Neuroscience Graduate Group University of Pennsylvania Philadelphia PA USA Department of Bioengineering School of Engineering & Applied Science University of Pennsylvania Philadelphia PA USA Annenberg School for Communication University of Pennsylvania Philadelphia PA USA Department of History and Sociology of Science College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Integrated Studies Program College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Integrated Studies Program College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Department of Philosophy College of Arts and Sciences University of Pennsylvania Philadelphia PA USA Department of Electrical & Systems Engineering School of Engineering & Applied Science University of Pennsylvania Philadelphia PA USA Department of Physics & Astronomy College of Arts & Sciences University of Pennsylvania Philadelphia PA USA Department of Neurology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Psychiatry Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Santa Fe Institute Santa Fe NM USA

Philosophers of science have long questioned how collective scientific knowledge grows. Although disparate answers have been posited, empirical validation has been challenging due to limitations in collecting and systematizing large historical records. Here, we introduce new methods to analyze scientific knowledge formulated as a growing network of articles on Wikipedia and their hyperlinks. We demonstrate that in Wikipedia, concept networks in subdisciplines of science do not grow by expanding from their central core to reach an ancillary periphery. Instead, science concept networks in Wikipedia grow by creating and filling knowledge gaps. Notably, the process of gap formation and closure may be valued by the scientific community, as evidenced by the fact that it produces discoveries that are more frequently awarded Nobel prizes than other processes. To determine whether and how the gap process is interrupted by paradigm shifts, we operationalize a paradigm as a particular subdivision of scientific concepts into network modules. Hence, paradigm shifts are reconfigurations of those modules. The approach allows us to identify a temporal signature in structural stability across scientific subjects in Wikipedia. In a network formulation of scientific discovery, our findings suggest that data-driven conditions underlying scientific breakthroughs depend as much on exploring uncharted gaps as on exploiting existing disciplines and support policies that encourage new interdisciplinary research.

关键词： science of science networks philosophy of science Wikipedia cavity

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Characterizing cellular mechanical phenotypes with mechanonode-pore sensing

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Microsystems & Nanoengineering 2018年第1期4卷 438-449页

作者： Junghyun Kim Sewoon Han Andy Lei Masaru Miyano Jessica Bloom Vasudha Srivastava Martha R.Stampfer Zev J.Gartner Mark A.LaBarge Lydia L.Sohn Department of Mechanical Engineering University of California at BerkeleyBerkeleyCA 94720-1740USA Department of Bioengineering University of California at BerkeleyBerkeleyCA 94720-1762USA Department of Population Sciences Beckman Research InstituteCity of HopeDuarteCA 91010USA Department of Pharmaceutical Chemistry University of CaliforniaSan FranciscoSan FranciscoCA 94143USA Biological Systems and Engineering Division Lawrence Berkeley National LaboratoryCA 94720USA Graduate Program in Bioengineering University of CaliforniaBerkeleyand University of CaliforniaSan FranciscoBerkeleyCA 94720USA

The mechanical properties of cells change with their differentiation,chronological age,and malignant ***,these properties may be useful label-free biomarkers of various functional or clinically relevant cell ***,we demonstrate mechano-node-pore sensing(mechano-NPS),a multi-parametric single-cell-analysis method that utilizes a four-terminal measurement of the current across a microfluidic channel to quantify simultaneously cell diameter,resistance to compressive deformation,transverse deformation under constant strain,and recovery time after *** define a new parameter,the whole-cell deformability index(wCDI),which provides a quantitative mechanical metric of the resistance to compressive deformation that can be used to discriminate among different cell *** wCDI and the transverse deformation under constant strain show malignant MCF-7 and A549 cell lines are mechanically distinct from non-malignant,MCF-10A and BEAS-2B cell lines,and distinguishes between cells treated or untreated with cytoskeleton-perturbing small *** categorize cell recovery time,ΔT_(r),as instantaneous(ΔTr~0 ms),transient(ΔT_(r)≤40 ms),or prolonged(ΔT_(r)>40 ms),and show that the composition of recovery types,which is a consequence of changes in cytoskeletal organization,correlates with cellular *** the wCDI and cell-recovery time,mechano-NPS discriminates between sub-lineages of normal primary human mammary epithelial cells with accuracy comparable to flow cytometry,but without antibody ***-NPS identifies mechanical phenotypes that distinguishes lineage,chronological age,and stage of malignant progression in human epithelial cells.

关键词： microfluidics mechanical phenotyping node-pore sensing biosensors label-free

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Design and Implementation of OLED Driving and OPD Readout Circuitry for an Optical Vibration Sensor 17

Design and Implementation of OLED Driving and OPD Readout Ci...

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17th IEEE SENSORS Conference, SENSORS 2018

作者： Wu, Yi-Cheng Kao, Yung-Hua Chao, Paul C.-P. Wey, Chin-Long Sauter, Thilo Eka, Fitrah P. Pandey, Rajeev Department of Electrical Engineering National Chiao Tung University Hsinchu300 Taiwan Institute of Electrical and Control Engineering National Chiao Tung University Hsinchu City Taiwan EECS International Graduate Program National Chiao Tung University Hsinchu City Taiwan Department for Integrated Sensor Systems Danube University Krems Austria Department of Electrical and Computer Engineering National Chiao Tung University Hsinchu City Taiwan

ISBN: (纸本)9781538647073

This study presents an organic light-emitting diode (OLED) drive circuit and an organic photo detector (OPD) readout circuits for a vibration sensor. Vibration sensor consist of micro-electro-mechanical systems (MEMS), which are OLED and OPD needs to be integrated for many applications in automation or consumer electronics. The light flux is generated by an OLED located on top of the structure and the modulated light flux is measured by an OPD. The OLED drive circuit contains pulse width modulation (PWM) driver to control PWM output for optimization of voltage operation is designed in order to minimize power consumption efficiency of device. The readout circuit includes a trans-impedance amplifier (TIA) to convert incident light of OPD to voltage output, a 14-bit analog-to-digital converter (ADC) to extract amplitude of vibration level, circuit to generate clock for time-to-digital converter (TDC) which detect frequency of vibration sensor. The designed circuit has been successfully fabricated by using TSMC 0.18 μm CMOS process, the chip area is 1.012 mm2. The power consumption of chip is about 6.2 mW. The measured frequency of PWM is about 200 kHz with 50% duty cycle. The frequency range of the vibration can be sensed well as about 10 Hz1.5 kHz, and resulting in high SNR at frequencies under 60 Hz. © 2018 IEEE.

关键词： Electric power utilization

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Retracted: Sylabus and Matrials Design for Vocational Student and Its Dissemination Using Website

Retracted: Sylabus and Matrials Design for Vocational Studen...

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2018 Workshop on Multidisciplinary and Its Applications: Applied Mathematics, Computer Science, Information systems, and Information Technology, WMA-Mathcomtech 2018

作者： Harahap, Astro Julida Ongko, Erianto Manurung, Hotler Kurnia, Dian Hartono, H. Abdullah, Dahlan Erliana, Cut Ita Djanggih, Hardianto Saddhono, Kundharu Rianita, Dian Setiawan, Muhammad Ikhsan Setiawan, Yuliyanto Budi Manurung, Rosida Tiurma Sriadhi, S. Sinurat, Mangasi Siregar, Aisyah Soni Hutauruk, Rapat Piter Sibarani, Nico Benjamain Department of Informatics Akademi Teknologi Industri Immanuel Medan Indonesia Department of Computer Systems Universitas Pancabudi Medan Indonesia Department of Computer Science STMIK IBBI Medan Indonesia Department of Informatics Universitas Malikussaleh Aceh Indonesia Department of Industrial Engineering Universitas Malikussaleh Aceh Indonesia Department of Law Universitas Tompotika Luwuk Banggai Indonesia Graduate Program Universitas Sebelas Maret Surakarta Indonesia Department of Administration University of Lancang Kuning Pekanbaru Indonesia Department of Civil Engineering Narotama University Surabaya Indonesia Study Program of Communication Studies Universitas Semarang Indonesia Graduate Program in Scientific Psychology Universitas Kristen Maranatha Indonesia Department of Electrical Engineering Universitas Negeri Medan Indonesia STIE Bina Karya Tebing Tinggi Indonesia

The learners' needs are an important factor in designing syllabus and materials design, this research deals with the syllabus and material design based on the professional's needs. It is expected that the syllabus and materials designes are communicatively applicable to the professional academy. Descriptive method is applied in this research. The sample of this research is 30 students of ATII Immanuel Academy Medan. They were selected by random sampling to get the data, the questioners were administered to students. the questioners consisted of 54 items and the semi structured interview consisted of 5 questions, the finding indicated that learners' needs were focused on reading and speaking skills. With reference appropriately and proportionally derived for students of the Professional Academy. Further on the basis of the syllabus, materials are designed in which the skills of using language become a priority. The results of this research will be disseminated using the website. © Published under licence by IOP Publishing Ltd.

关键词： Information systems

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Cryptocurrencies Transactions Advisor Using a Genetic Mamdani-type Fuzzy Rules Based System

Cryptocurrencies Transactions Advisor Using a Genetic Mamdan...

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IEEE International Conference on Fuzzy systems (FUZZ-IEEE)

作者： Taiguara Melo Tupinambás Rafael Aeraf Leão Cadence André Paim Lemos Graduate Program in Electrical Engineering Federal University of Minas Gerais Belo Horizonte Minas Gerais Design Systems Inc. Belo Horizonte Minas Gerais

Cryptocurrencies prices forecasting is a complex theme due to the chaotic market behavior and the influence of external events. Therefore, inference models should offer, in addition to a satisfying accuracy, reasonable interpretability, so that investors can decide based on their own knowledge. However, many studies in this subject focus on model accuracy and leave much to be desired in terms of simplicity and interpretability. This work proposes the use of Mamdani interpretable fuzzy inference models for forecasting cryptocurrency price variation. For that, a genetic algorithm to optimize models accuracy is employed, limiting the quantity of rules and antecedents arbitrarily. A set of infeasible rules had to be discarded, in order to generate interesting models, that produce a relevant amount of trades. Data from Kraken exchange were utilized for training, validation and results assessment. Results have shown that, for the cryptocurrencies with the highest validation performances, there are gains in comparison to the simple currency appreciation. Using the interpretable aspect of the models, it should be possible to obtain even higher profits.

关键词： Genetic algorithms Bitcoin Sociology Statistics Linguistics Forecasting

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Revised JNLPBA corpus: A revised version of biomedical NER corpus for relation extraction task

arXiv

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arXiv 2019年

作者： Huang, Ming-Siang Lai, Po-Ting Tsai, Richard Tzong-Han Hsu, Wen-Lian Bioinformatics Program Taiwan International Graduate Program Institute of Information Science Academia Sinica Taipei Taiwan Institute of Biomedical Informatics National Yang Ming University Taipei Taiwan Department of Computer Science National Tsing-Hua University Hsinchu Taiwan Intelligent Agent Systems Laboratory Institute of Information Science Academia Sinica Taipei Taiwan Intelligent Information Service Research Laboratory Department of Computer Science and Information Engineering National Central University Taoyuan Taiwan

The advancement of biomedical named entity recognition (BNER) and biomedical relation extraction (BRE) researches promotes the development of text mining in biological domains. As a cornerstone of BRE, robust BNER system is required to identify the mentioned NEs in plain texts for further relation extraction stage. However, the current BNER corpora, which play important roles in these tasks, paid less attention to achieve the criteria for BRE task. In this study, we present Revised JNLPBA corpus, the revision of JNLPBA corpus, to broaden the applicability of a NER corpus from BNER to BRE task. We preserve the original entity types including protein, DNA, RNA, cell line and cell type while all the abstracts in JNLPBA corpus are manually curated by domain experts again basis on the new annotation guideline focusing on the specific NEs instead of general terms. Simultaneously, several imperfection issues in JNLPBA are pointed out and made up in the new corpus. To compare the adaptability of different NER systems in Revised JNLPBA and JNLPBA corpora, the F1-measure was measured in three open sources NER systems including BANNER, Gimli and NERSuite. In the same circumstance, all the systems perform average 10% better in Revised JNLPBA than in JNLPBA. Moreover, the cross-validation test is carried out which we train the NER systems on JNLPBA/Revised JNLPBA corpora and access the performance in both protein-protein interaction extraction (PPIE) and biomedical event extraction (BEE) corpora to confirm that the newly refined Revised JNLPBA is a competent NER corpus in biomedical relation application. The revised JNLPBA corpus is freely available at ***/BNER/Content/Revised_***. Copyright © 2019, The Authors. All rights reserved.

关键词： Proteins

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Innovation measurement in clusters of information technology companies: Multi-case study in a Brazilian it LPA (local production arrangement) 24

Innovation measurement in clusters of information technology...

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24th International Conference on Production Research, ICPR 2017

作者： Semler, R.F. Piovesan, A.C. Avancini Schenatto, F.J. Adamczuk Oliveira, G. Stricto Sensu Graduate Program in Production Systems Engineering Federal Technological University of Paraná Campus Pato Branco Brazil

ISBN: (纸本)9781605955070

This article aims to analyze the innovation scores of IT companies and their respective clusters, resulting in a tool for constructing knowledge about these companies and gaining useful information for comparison purposes, since few studies are focused on innovation in Brazilian IT companies, especially microenterprises. A case study methodology was used in this research, and to measure innovation, the model proposed by Edison, Ali and Tonkar (2013) was used. The target audience was the LPA of information technology companies in southwest Paraná, being composed of 50 companies divided into 3 clusters. The data collection was based on a survey with 43 questions built according to the Likert Scale. As a result of the application of the Kruskall-Wallis test, with 5% significance, it was observed that there is a difference between the innovation scores of each cluster, with Clusters 1 and 3 having higher scores. As for the relationship between innovation and turnover, the Spearman Correlation test, with 5% significance, showed that there is a moderate relationship between innovation scores and company turnover. Measuring innovation, both individually and in clusters, is important in the information technology sector because it allows management to see weaknesses and strengths, and implement improvements and changes that ensure increased competitiveness and permanence in the market. © 2017 DEStech Publications. All rights reserved.

关键词： Cluster Information technology Innovation

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The Application of Reference Ontologies for Semantic Interoperability in an Integrated Product Development Process in Smart Factories

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Procedia Manufacturing 2017年 11卷 1375-1384页

作者： Szejka, Anderson Luis Junior, Osiris Canciglieri Industrial and Systems Engineering Graduate Program Pontifical Catholic University of Parana Imaculada Conceição 1155 Curitiba 80215-901 Paraná Brazil

Efficient information sharing demands formal information structures in order to make sure the semantic interoperability across different phases of Product Development Process. This research presents an application of reference ontologies to support semantic interoperability during the Product Development Process. The concepts inherent to the product development process are formalized in reference ontologies and these ontologies are specialized according to the specific product data, respecting semantic rules. As a result, the potential benefits and limitations of the ontology-driven interoperability were discussed, contributing to the semantic interoperability field and improving the product and manufacturing design. © 2017 The Authors

关键词： Decision-Making support Integrated Product Development Process Multiple Domains Ontology Semantic Interoperability Smart Factories

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Spatiotemporal development of expanding bacterial colonies driven by emergent mechanical constraints and nutrient gradients

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Nature communications 2025年第1期16卷 4878页

作者： Harish Kannan Hui Sun Mya Warren Tolga Çağlar Pantong Yao Brian R Taylor Kinshuk Sahu Daotong Ge Matteo Mori David Kleinfeld JiaJia Dong Bo Li Terence Hwa Department of Mathematics University of California San Diego La Jolla CA USA. Department of Mathematics and Statistics California State University Long Beach CA USA. paul.sun@csulb.edu. Department of Physics University of California San Diego La Jolla CA USA. San Diego Supercomputer Center University of California San Diego La Jolla CA USA. Neurosciences Graduate Program University of California San Diego La Jolla CA USA. Joint BioEnergy Institute Emeryville CA USA and Systems Biology Department Sandia National Laboratories Livermore CA USA. Department of Bioengineering University of California San Diego La Jolla CA USA. Department of Biomedical Engineering Duke University Durham NC USA. Department of Neurobiology University of California San Diego La Jolla CA USA. Department of Physics & Astronomy Bucknell University Lewisburg PA USA. jiajia.dong@bucknell.edu. Department of Mathematics and Ph.D. Program in Quantitative Biology University of California San Diego La Jolla CA USA. bli@ucsd.edu. Department of Physics University of California San Diego La Jolla CA USA. hwa@ucsd.edu.

Bacterial colonies growing on solid surfaces can exhibit robust expansion kinetics, with constant radial growth and saturating vertical expansion, suggesting a common developmental program. Here, we study this process for Escherichia coli cells using a combination of modeling and experiments. We show that linear radial colony expansion is set by the verticalization of interior cells due to mechanical constraints rather than radial nutrient gradients as commonly assumed. In contrast, vertical expansion slows down from an initial linear regime even while radial expansion continues linearly. This vertical slowdown is due to limitation of cell growth caused by vertical nutrient gradients, exacerbated by concurrent oxygen depletion. Starvation in the colony interior results in a distinct death zone which sets in as vertical expansion slows down, with the death zone increasing in size along with the expanding colony. Thus, our study reveals complex heterogeneity within simple monoclonal bacterial colonies, especially along the vertical dimension. The intricate dynamics of such emergent behavior can be understood quantitatively from an interplay of mechanical constraints and nutrient gradients arising from obligatory metabolic processes.

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