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arXiv 2023年

作者： Lekadir, Karim Feragen, Aasa Fofanah, Abdul Joseph Frangi, Alejandro F. Buyx, Alena Emelie, Anais Lara, Andrea Porras, Antonio R. Chan, An-Wen Navarro, Arcadi Glocker, Ben Botwe, Benard O. Khanal, Bishesh Beger, Brigit Wu, Carol C. Cintas, Celia Langlotz, Curtis P. Rueckert, Daniel Mzurikwao, Deogratias Fotiadis, Dimitrios I. Zhussupov, Doszhan Ferrante, Enzo Meijering, Erik Weicken, Eva González, Fabio A. Asselbergs, Folkert W. Prior, Fred Krestin, Gabriel P. Collins, Gary S. Tegenaw, Geletaw S. Kaissis, Georgios Misuraca, Gianluca Tsakou, Gianna Dwivedi, Girish Kondylakis, Haridimos Jayakody, Harsha Woodruf, Henry C. Mayer, Horst Joachim Aerts, Hugo JWL Walsh, Ian Chouvarda, Ioanna Buvat, Irène Tributsch, Isabell Rekik, Islem Duncan, James Kalpathy-Cramer, Jayashree Zahir, Jihad Park, Jinah Mongan, John Gichoya, Judy W. Schnabel, Julia A. Kushibar, Kaisar Riklund, Katrine Mori, Kensaku Marias, Kostas Amugongo, Lameck M. Fromont, Lauren A. Maier-Hein, Lena Alberich, Leonor Cerdá Rittner, Leticia Phiri, Lighton Marrakchi-Kacem, Linda Donoso-Bach, Lluís Martí-Bonmatí, Luis Cardoso, M. Jorge Bobowicz, Maciej Shabani, Mahsa Tsiknakis, Manolis Zuluaga, Maria A. Bielikova, Maria Fritzsche, Marie-Christine Camacho, Marina Linguraru, Marius George Wenzel, Markus De Bruijne, Marleen Tolsgaard, Martin G. Ghassemi, Marzyeh Ashrafuzzaman, Md Goisauf, Melanie Yaqub, Mohammad Abadía, Mónica Cano Mahmoud, Mukhtar M.E. Elattar, Mustafa Rieke, Nicola Papanikolaou, Nikolaos Lazrak, Noussair Díaz, Oliver Salvado, Olivier Pujol, Oriol Sall, Ousmane Guevara, Pamela Gordebeke, Peter Lambin, Philippe Brown, Pieta Abolmaesumi, Purang Dou, Qi Lu, Qinghua Osuala, Richard Nakasi, Rose Zhou, S. Kevin Napel, Sandy Colantonio, Sara Albarqouni, Shadi Joshi, Smriti Carter, Stacy Klein, Stefan Petersen, Steffen E. Aussó, Susanna Awate, Suyash Raviv, Tammy Riklin Cook, Tessa Mutsvangwa, Tinashe E.M. Rogers, Wendy A. Niessen, Wiro J. Puig-Bosch, Xènia Zeng, Yi Mohammed, Yunusa G. Aquino, Yves Saint James Salahuddin, Zohaib Starmans, Martijn P.A. Department de Matemàtiques i Informàtica Universitat de Barcelona Barcelona Spain Barcelona Spain DTU Compute Technical University of Denmark Kgs Lyngby Denmark Department of Mathematics and Computer Science Faculty of Science and Technology Milton Margai Technical University Freetown Sierra Leone Center for Computational Imaging & Simulation Technologies in Biomedicine Schools of Computing and Medicine University of Leeds Leeds United Kingdom Cardiovascular Science and Electronic Engineering Departments KU Leuven Leuven Belgium Institute of History and Ethics in Medicine Technical University of Munich Munich Germany Faculty of Engineering of Systems Informatics and Sciences of Computing Galileo University Guatemala City Guatemala Department of Biostatistics and Informatics Colorado School of Public Health University of Colorado Anschutz Medical Campus AuroraCO United States Department of Medicine Women’s College Research Institute University of Toronto Toronto Canada Universitat Pompeu Fabra BarcelonaBeta Brain Research Center Barcelona Spain Department of Computing Imperial College London London United Kingdom School of Biomedical & Allied Health Sciences University of Ghana Accra Ghana Department of Midwifery & Radiography School of Health & Psychological Sciences City University of London United Kingdom Kathmandu Nepal European Heart Network Brussels Belgium Department of Thoracic Imaging University of Texas MD Anderson Cancer Center Houston United States IBM Research Africa Nairobi Kenya Departments of Radiology Medicine and Biomedical Data Science Stanford University School of Medicine Stanford United States Institute for AI and Informatics in Medicine Klinikum rechts der Isar Technical University Munich Munich Germany Department of Computing Imperial College London London United Kingdom Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania United Republic of Ioannina Greece Almaty AI Lab Almaty Kazakhstan

Background: Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. In recent years, concerns have been raised about the clinical, technical, ethical and legal risks associated with healthcare AI. To increase adoption in the real world, it is essential that AI technologies are trusted and accepted by patients, clinicians, health organisations and authorities. This paper describes the FUTURE-AI framework as the first international consensus guideline for trustworthy AI in healthcare. Methods: The FUTURE-AI consortium was founded in 2021 and now comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedical ethicists, and social scientists. Over a two-year period, the consortium established guiding principles and best practices for trustworthy and deployable AI through an iterative process comprising an in-depth literature review, a modified Delphi survey, and online consensus meetings. Findings: The FUTURE-AI framework was established based on six guiding principles for trustworthy AI in healthcare, i.e. Fairness, Universality, Traceability, Usability, Robustness and Explainability. Through consensus, a set of 30 best practices were defined, addressing technical, clinical, socio-ethical and legal dimensions of trustworthy AI. The recommendations cover the entire lifecycle of healthcare AI, from design, development and validation to regulation, deployment, and monitoring. Interpretation: FUTURE-AI is a structured, risk-informed framework which provides guidance for constructing healthcare AI tools that will be trusted, deployed and adopted in real-world clinical practice. Researchers are encouraged to take the recommendations into account in proof-of-concept stages to facilitate future translation towards clinical practice of healthcare AI. Copyright © 2023, The Authors. All rights

关键词： Clinical research

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Author Correction: Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis

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Nature communications 2023年第1期14卷 6540页

作者： Hitomi Takada Yohei Sasagawa Mika Yoshimura Kaori Tanaka Yoshimi Iwayama Tetsutaro Hayashi Ayako Isomura-Matoba Itoshi Nikaido Akira Kurisaki Laboratory of Stem Cell Technologies Graduate School of Science and Technology Nara Institute of Science and Technology Takayama-cho Ikoma Nara Japan. Laboratory for Bioinformatics Research RIKEN Center for Biosystems Dynamics Research Wako Saitama Japan. Department of Functional Genome Informatics Biological Data Science Medical Research Institute Tokyo Medical and Dental University Bunkyo Tokyo Japan. Laboratory for Bioinformatics Research RIKEN Center for Biosystems Dynamics Research Wako Saitama Japan. itoshi.nikaido@riken.jp. Department of Functional Genome Informatics Biological Data Science Medical Research Institute Tokyo Medical and Dental University Bunkyo Tokyo Japan. itoshi.nikaido@riken.jp. Master's/Doctoral Program in Life Science Innovation (Bioinformatics) Degree Programs in Systems and Information Engineering Graduate School of Science and Technology University of Tsukuba Tsukuba Ibaraki Japan. itoshi.nikaido@riken.jp. Laboratory of Stem Cell Technologies Graduate School of Science and Technology Nara Institute of Science and Technology Takayama-cho Ikoma Nara Japan. akikuri@bs.naist.jp.

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EMPRESS. IX. Extremely Metal-Poor Galaxies are Very Gas-Rich Dispersion-Dominated Systems: Will JWST Witness Gaseous Turbulent High-z Primordial Galaxies?

arXiv

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arXiv 2022年

作者： Isobe, Yuki Ouchi, Masami Nakajima, Kimihiko Ozaki, Shinobu Bouché, Nicolas F. Wise, John H. Xu, Yi Emsellem, Eric Kusakabe, Haruka Hattori, Takashi Nagao, Tohru Chiaki, Gen Fukushima, Hajime Harikane, Yuichi Hayashi, Kohei Hirai, Yutaka Kim, Ji Hoon Maseda, Michael V. Nagamine, Kentaro Shibuya, Takatoshi Sugahara, Yuma Yajima, Hidenobu Aoyama, Shohei Fujimoto, Seiji Fukushima, Keita Hatano, Shun Inoue, Akio K. Ishigaki, Tsuyoshi Kawasaki, Masahiro Kojima, Takashi Komiyama, Yutaka Koyama, Shuhei Koyama, Yusei Lee, Chien-Hsiu Matsumoto, Akinori Mawatari, Ken Moriya, Takashi J. Motohara, Kentaro Murai, Kai Nishigaki, Moka Onodera, Masato Ono, Yoshiaki Rauch, Michael Saito, Tomoki Sasaki, Rin Suzuki, Akihiro Takeuchi, Tsutomu T. Umeda, Hiroya Umemura, Masayuki Watanabe, Kuria Yabe, Kiyoto Zhang, Yechi Institute for Cosmic Ray Research The University of Tokyo 5-1-5 Kashiwanoha Chiba Kashiwa277-8582 Japan Department of Physics Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan University of Tokyo Chiba Kashiwa277-8583 Japan Univ Lyon Univ Lyon1 ENS de Lyon CNRS Centre de Recherche Astrophysique de Lyon UMR5574 Saint-Genis-LavalF-69230 France Center for Relativistic Astrophysics School of Physics Georgia Institute of Technology AtlantaGA30332 United States Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan European Southern Observatory Karl-Schwarzschild-Straße 2 Garching85748 Germany Observatoire de Genéve Université de Genéve 51 Ch. des Maillettes Versoix1290 Switzerland 650 North A'ohoku Place HiloHI96720 United States Research Center for Space and Cosmic Evolution Ehime University Bunkyo-cho 2-5 Ehime Matsuyama790-8577 Japan Center for Computational Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki305-8577 Japan Department of Physics and Astronomy University College London Gower Street LondonWC1E 6BT United Kingdom National Institute of Technology Ichinoseki College Hagisho Ichinoseki021-8511 Japan Astronomical Institute Tohoku University 6-3 Aoba Aramaki Aoba-ku Miyagi Sendai980-8578 Japan Department of Physics and Astronomy University of Notre Dame 225 Nieuwland Science Hall Notre DameIN46556 United States Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of Department of Astronomy University of Wisconsin-Madison 475 N. Charter Street MadisonWI53706 United States Theoretical Astrophysics Department of Earth & Space S

We present kinematics of 6 local extremely metal-poor galaxies (EMPGs) with low metallicities (0.016 − 0.098 Z☉) and low stellar masses (104.7 − 107.6M☉). Taking deep medium-high resolution (R ∼ 7500) integral-field spectra with 8.2-m Subaru, we resolve the small inner velocity gradients and dispersions of the EMPGs with Hα emission. Carefully masking out sub-structures originated by inflow and/or outflow, we fit 3-dimensional disk models to the observed Hα flux, velocity, and velocity-dispersion maps. All the EMPGs show rotational velocities (vrot) of 5-23 km s−1 smaller than the velocity dispersions (σ0) of 17-31 km s−1, indicating dispersion-dominated (vrot/σ0 = 0.29−0.80 gas 0.9 − 1.0. Comparing our results with other Hα kinematics studies, we find that vrot/σ0 decreases and fgas increases with decreasing metallicity, decreasing stellar mass, and increasing specific star-formation rate. We also find that simulated high-z (z ∼ 7) forming galaxies have gas fractions and dynamics similar to the observed EMPGs. Our EMPG observations and the simulations suggest that primordial galaxies are gas-rich dispersion-dominated systems, which would be identified by the forthcoming James Webb Space Telescope (JWST) observations at z ∼ 7. Copyright © 2022, The Authors. All rights reserved.

关键词： Galaxies

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High-depth African genomes inform human migration and health (vol 586, pg 741, 2020)

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NATURE 2021年第7856期592卷 E26-E26页

作者： Choudhury, Ananyo Aron, Shaun Botigue, Laura R. Sengupta, Dhriti Botha, Gerrit Bensellak, Taoufik Wells, Gordon Kumuthini, Judit Shriner, Daniel Fakim, Yasmina J. Ghoorah, Anisah W. Dareng, Eileen Odia, Trust Falola, Oluwadamilare Adebiyi, Ezekiel Hazelhurst, Scott Mazandu, Gaston Nyangiri, Oscar A. Mbiyavanga, Mamana Benkahla, Alia Kassim, Samar K. Mulder, Nicola Adebamowo, Sally N. Chimusa, Emile R. Muzny, Donna Metcalf, Ginger Gibbs, Richard A. Matovu, Enock Bucheton, Bruno Hertz-Fowler, Christiane Koffi, Mathurin Macleod, Annette Mumba-Ngoyi, Dieudonne Noyes, Harry Nyangiri, Oscar A. Simo, Gustave Simuunza, Martin Rotimi, Charles Ramsay, Michele Choudhury, Ananyo Choudhury, Ananyo Aron, Shaun Botigue, Laura Sengupta, Dhriti Botha, Gerrit Bensellak, Taoufik Wells, Gordon Kumuthini, Judit Shriner, Daniel Fakim, Yasmina J. Ghoorah, Anisah W. Dareng, Eileen Odia, Trust Falola, Oluwadamilare Adebiyi, Ezekiel Hazelhurst, Scott Mazandu, Gaston Nyangiri, Oscar A. Mbiyavanga, Mamana Benkahla, Alia Kassim, Samar K. Mulder, Nicola Adebamowo, Sally N. Chimusa, Emile R. Rotimi, Charles Ramsay, Michele Adeyemo, Adebowale A. Lombard, Zane Hanchard, Neil A. Adebamowo, Clement Agongo, Godfred Boua, Romuald P. Oduro, Abraham Sorgho, Hermann Landoure, Guida Cisse, Lassana Diarra, Salimata Samassekou, Oumar Anabwani, Gabriel Matshaba, Mogomotsi Joloba, Moses Kekitiinwa, Adeodata Mardon, Graeme Mpoloka, Sununguko W. Kyobe, Samuel Mlotshwa, Busisiwe Mwesigwa, Savannah Retshabile, Gaone Williams, Lesedi Wonkam, Ambroise Moussa, Ahmed Adu, Dwomoa Ojo, Akinlolu Burke, David Salako, Babatunde O. Matovu, Enock Bucheton, Bruno Hertz-Fowler, Christiane Koffi, Mathurin Macleod, Annette Mumba-Ngoyi, Dieudonne Noyes, Harry Nyangiri, Oscar A. Simo, Gustave Simuunza, Martin Awadalla, Philip Bruat, Vanessa Gbeha, Elias Adeyemo, Adebowale A. Lombard, Zane Hanchard, Neil A. Sydney Brenner Institute for Molecular Bioscience Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa School of Electrical and Information Engineering University of the Witwatersrand Johannesburg South Africa Division of Human Genetics National Health Laboratory Service and School of Pathology Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa Navrongo Health Research Centre Navrongo Ghana Clinical Research Unit of Nanoro Institut de Recherche en Sciences de la Sante Bobo-Dioulasso Burkina Faso Center for Research in Agricultural Genomics (CRAG) Plant and Animal Genomics Program CSIC-IRTA-UAB-UB Barcelona Spain Computational Biology Division and H3ABioNet Department of Integrative Biomedical Sciences IDM University of Cape Town Cape Town South Africa System and Data Engineering Team Abdelmalek Essaadi University ENSA Tangier Morocco Centre for Proteomic and Genomic Research (CPGR) Cape Town South Africa South African National Bioinformatics Institute University of the Western Cape Bellville South Africa Africa Health Research Institute Durban South Africa Center for Research on Genomics and Global Health National Human Genome Research Institute National Institutes of Health Bethesda MD USA Department of Agriculture and Food Science Faculty of Agriculture University of Mauritius Reduit Mauritius Department of Digital Technologies Faculty of Information Communication & Digital Technologies University of Mauritius Reduit Mauritius Department of Public Health and Primary Care University of Cambridge Cambridge UK Institute of Human Virology Nigeria Abuja Nigeria Department of Epidemiology and Public Health University of Maryland School of Medicine University of Maryland Baltimore Baltimore MD USA University of Maryland Greenebaum Comprehensive Cancer Center University of Maryland School of Medicine University of Maryland Baltimore Baltimore MD USA Institute of Human Virology and Greeneba

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EMPRESS. XII. Statistics on the Dynamics and Gas Mass Fraction of Extremely-Metal Poor Galaxies

arXiv

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arXiv 2023年

作者： Xu, Yi Ouchi, Masami Isobe, Yuki Nakajima, Kimihiko Ozaki, Shinobu Bouché, Nicolas F. Wise, John H. Emsellem, Eric Kusakabe, Haruka Hattori, Takashi Nagao, Tohru Chiaki, Gen Fukushima, Hajime Harikane, Yuichi Hayashi, Kohei Hirai, Yutaka Kim, Ji Hoon Maseda, Michael V. Nagamine, Kentaro Shibuya, Takatoshi Sugahara, Yuma Yajima, Hidenobu Aoyama, Shohei Fujimoto, Seiji Fukushima, Keita Hatano, Shun Inoue, Akio K. Ishigaki, Tsuyoshi Kawasaki, Masahiro Kojima, Takashi Komiyama, Yutaka Koyama, Shuhei Koyama, Yusei Lee, Chien-Hsiu Matsumoto, Akinori Mawatari, Ken Moriya, Takashi J. Motohara, Kentaro Murai, Kai Nishigaki, Moka Onodera, Masato Ono, Yoshiaki Rauch, Michael Saito, Tomoki Sasaki, Rin Suzuki, Akihiro Takeuchi, Tsutomu T. Umeda, Hiroya Umemura, Masayuki Watanabe, Kuria Yabe, Kiyoto Zhang, Yechi Institute for Cosmic Ray Research The University of Tokyo 5-1-5 Kashiwanoha Chiba Kashiwa277-8582 Japan Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan University of Tokyo Chiba Kashiwa277-8583 Japan Department of Physics Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan Univ Lyon Univ Lyon1 ENS de Lyon CNRS Centre de Recherche Astrophysique de Lyon UMR5574 Saint-Genis-LavalF-69230 France Center for Relativistic Astrophysics School of Physics Georgia Institute of Technology AtlantaGA30332 United States European Southern Observatory Karl-Schwarzschild-Straße 2 Garching85748 Germany Observatoire de Genéve Université de Genéve 51 Ch. des Maillettes Versoix1290 Switzerland 650 North A’ohoku Place HiloHI96720 United States Research Center for Space and Cosmic Evolution Ehime University Bunkyo-cho 2-5 Ehime Matsuyama790-8577 Japan Center for Computational Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki305-8577 Japan Department of Physics and Astronomy University College London Gower Street LondonWC1E 6BT United Kingdom National Institute of Technology Ichinoseki College Hagisho Ichinoseki021-8511 Japan Astronomical Institute Tohoku University 6-3 Aoba Aramaki Aoba-ku Miyagi Sendai980-8578 Japan Department of Physics and Astronomy University of Notre Dame 225 Nieuwland Science Hall Notre DameIN46556 United States Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of Department of Astronomy University of Wisconsin-Madison 475 N. Charter Street MadisonWI53706 United States Theoretical Astrophysics Department of Earth & Space S

We present demography of the dynamics and gas-mass fraction of 33 extremely metal-poor galaxies (EMPGs) with metallicities of 0.015 − 0.195 Zo and low stellar masses of 104 − 108 Mo in the local universe. We conduct deep optical integral-field spectroscopy (IFS) for the low-mass EMPGs with the medium high resolution (R = 7500) grism of the 8m-Subaru FOCAS IFU instrument by the EMPRESS 3D survey, and investigate Hα emission of the EMPGs. Exploiting the resolution high enough for the low-mass galaxies, we derive gas dynamics with the Hα lines by the fitting of 3-dimensional disk models. We obtain an average maximum rotation velocity (vrot) of 15 ± 3 km s−1 and an average intrinsic velocity dispersion (σ0) of 27 ± 10 km s−1 for 15 spatially resolved EMPGs out of the 33 EMPGs, and find that all of the 15 EMPGs have vrot/σ0 rot/σ0 with the decreasing stellar mass and metallicity. We derive the gas mass fraction (fgas) for all of the 33 EMPGs, and find no clear dependence on stellar mass and metallicity. These vrot/σ0 and fgas trends should be compared with young high-z galaxies observed by the forthcoming JWST IFS programs to understand the physical origins of the EMPGs in the local universe. © 2023, CC BY.

关键词： Galaxies

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EMPRESS. X. Spatially resolved mass-metallicity relation in extremely metal-poor galaxies: Evidence of episodic star-formation fueled by a metal-poor gas infall

arXiv

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arXiv 2024年

作者： Nakajima, Kimihiko Ouchi, Masami Isobe, Yuki Xu, Yi Ozaki, Shinobu Nagao, Tohru Inoue, Akio K. Rauch, Michael Kusakabe, Haruka Onodera, Masato Nishigaki, Moka Ono, Yoshiaki Sugahara, Yuma Hattori, Takashi Hirai, Yutaka Hashimoto, Takuya Kim, Ji Hoon Moriya, Takashi J. Yanagisawa, Hiroto Aoyama, Shohei Fujimoto, Seiji Fukushima, Hajime Fukushima, Keita Harikane, Yuichi Hatano, Shun Hayashi, Kohei Ishigaki, Tsuyoshi Kawasaki, Masahiro Kojima, Takashi Komiyama, Yutaka Koyama, Shuhei Koyama, Yusei Lee, Chien-Hsiu Matsumoto, Akinori Mawatari, Ken Motohara, Kentaro Murai, Kai Nagamine, Kentaro Nakane, Minami Saito, Tomoki Sasaki, Rin Shibuya, Takatoshi Suzuki, Akihiro Takeuchi, Tsutomu T. Umeda, Hiroya Umemura, Masayuki Watanabe, Kuria Yabe, Kiyoto Yajima, Hidenobu Zhang, Yechi National Astronomical Observatory of Japan 2-21-1 Osawa Mitaka Tokyo181-8588 Japan Institute for Cosmic Ray Research The University of Tokyo 5-1-5 Kashiwanoha Chiba Kashiwa277-8582 Japan Osawa 2-21-1 Mitaka Tokyo181-8588 Japan University of Tokyo Chiba Kashiwa277-8583 Japan Kavli Institute for Cosmology University of Cambridge Madingley Road CambridgeCB3 0HA United Kingdom Cavendish Laboratory University of Cambridge 19 JJ Thomson Avenue CambridgeCB3 0HE United Kingdom Waseda Research Institute for Science and Engineering Faculty of Science and Engineering Waseda University 3-4-1 Okubo Shinjuku Tokyo169-8555 Japan Department of Physics Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan Department of Astronomy Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo Tokyo113-0033 Japan Research Center for Space and Cosmic Evolution Ehime University Bunkyo-cho 2-5 Ehime Matsuyama790-8577 Japan Department of Physics School of Advanced Science and Engineering Faculty of Science and Engineering Waseda University 3-4-1 Okubo Shinjuku Tokyo169-8555 Japan Observatories of the Carnegie Institution for Science 813 Santa Barbara St. PasadenaCA91101 United States Observatoire de Genève Université de Genève 51 Chemin de Pégase Versoix1290 Switzerland 650 North Aohoku Place HiloHI96720 United States Department of Physics and Astronomy University of Notre Dame 225 Nieuwland Science Hall Notre DameIN46556 United States Astronomical Institute Tohoku University 6-3 Aoba Aramaki Aoba-ku Miyagi Sendai980-8578 Japan Division of Physics Faculty of Pure and Applied Sciences University of Tsukuba Ibaraki Tsukuba305-8571 Japan Faculty of Pure and Applied Sciences University of Tsukuba Ibaraki Tsukuba305-8571 Japan Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Cent

Using the Subaru/FOCAS IFU capability, we examine the spatially resolved relationships between gas-phase metallicity, stellar mass, and star-formation rate surface densities (Σ★ and ΣSFR, respectively) in extremely metal-poor galaxies (EMPGs) in the local universe. Our analysis includes 24 EMPGs, comprising 9,177 spaxels, which span a unique parameter space of local metallicity (12 + log(O/H) 6.9 to 7.9) and stellar mass surface density (Σ★ ∼ 105 to 107 Mo kpc−2), extending beyond the range of existing large integral-field spectroscopic surveys. Through spatially resolved emission line diagnostics based on the [N ii] BPT-diagram, we verify the absence of evolved active galactic nuclei in these EMPGs. Our findings reveal that, while the resolved mass-metallicity relation exhibits significant scatter in the low-mass regime, this scatter is closely correlated with local star-formation surface density. Specifically, metallicity decreases as ΣSFR increases for a given Σ★. Notably, half of the EMPGs show a distinct metal-poor horizontal branch on the resolved mass-metallicity relation. This feature typically appears at the peak clump with the highest Σ★ and ΣSFR and is surrounded by a relatively metal-enriched ambient region. These findings support a scenario in which metal-poor gas infall fuels episodic star formation in EMPGs, consistent with the kinematic properties observed in these systems. In addition, we identify four EMPGs with exceptionally low central metallicities (12 + log(O/H) 7.2), which display only a metal-poor clump without a surrounding metal-rich region. This suggests that such ultra-low metallicity EMPGs, at less than a few percent of the solar metallicity, may serve as valuable analogs for galaxies in the early stages of galaxy evolution. Copyright © 2024, The Authors. All rights reserved.

关键词： Spectroscopic analysis

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Blended learning and media centers: A bibliometric analysis

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Social Sciences and Humanities Open 2024年 10卷

作者： Challco, Geiser Chalco Silva, Wesley Vieira da Setton Gonçalves, Bruno de Almeida Levino, Natallya Bittencourt, Ibsen Mateus Kaczam, Fabíola de Oliveira, Elaine Harada Teixeira Martins, Flavio Pinheiro de Lima Filho, Walter Araujo de Araújo, Ronaldo Ferreira Bittencourt, Ig Ibert Paiva, Ranilson Oscar Araújo Department of Engineering and Technology (DETEC) Federal Rural University of Semi-Árido (UFERSA) RN Pau dos Ferros 59900-000 Brazil Scholarship CNPq Research Productivity (D Level) and Professor Faculty of Economics Administration and Accounting Federal University of Alagoas (UFAL) Maceió 57072-900 Brazil Faculty of Economics Administration and Accounting Federal University of Alagoas (UFAL) Maceió 57072-900 Brazil Leader of the Laboratory of Applied Public Administration (LAPA) of the Public Administration Course Campus Arapirca Federal University of Alagoas Arapiraca 57309-005 Brazil Faculty of Economics Business and Accounting Federal University of Alagoas Maceio 57072-900 Brazil Postgraduate Program in Administration Federal University Santa Maria (UFSM) Building 74C 2nd floor Room 4209 97105-900 Brazil Institute of Computing Federal University of Amazonas Amazonas Manaus Brazil The Bartlett School of Sustainable Construction University College London—UCL London WC1E 6BT United Kingdom Visiting Researcher at Leiden University ou Pesquisador Visitante na Universidade de Leiden Institute of Human Sciences Communication and Arts Federal University of Alagoas Alagoas Maceio 57072-900 Brazil Harvard Graduate School of Education Harvard University Cambridge MA United States Center of Excellence for Social Technologies Federal University of Alagoas Brazil Universidade Federal de Alagoas - Instituto de Computação Brazil

Blended learning can be considered an approach that combines face-to-face and online periods in education through the integration of some technological resources, such as media centers. The present research sought to investigate the panorama of scientific production on blended learning and identify evidence of how media centers are used to support this type of teaching. This is a bibliometric study carried out based on the principles of the Systematic Literature Review (SLR). Although the results indicate an increase in production, a high rate of authors with only one published work was identified, which can be interpreted as an expanding topic. The United States stood out as the country that contributed the most with research and the areas of Computer Science and Education among the fields of research with the highest number of articles. © 2024 The Author(s)

关键词： Blended learning Hybrid education Media centers Systematic review

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SciPy 1.0—Fundamental algorithms for scientific computing in python

arXiv

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arXiv 2019年

作者： Virtanen, Pauli Gommers, Ralf Oliphant, Travis E. Haberland, Matt Reddy, Tyler Cournapeau, David Burovski, Evgeni Peterson, Pearu Weckesser, Warren Bright, Jonathan van der Walt, Stéfan J. Brett, Matthew Wilson, Joshua Millman, K. Jarrod Mayorov, Nikolay Nelson, Andrew R.J. Jones, Eric Kern, Robert Larson, Eric Carey, C.J. Polat, Ilhan Feng, Yu Moore, Eric W. VanderPlas, Jake Laxalde, Denis Perktold, Josef Cimrman, Robert Henriksen, Ian Quintero, E.A. Harris, Charles R. Archibald, Anne M. Ribeiro, Antônio H. Pedregosa, Fabian van Mulbregt, Paul University of Jyväskylä University of Jyväskylä FI-40014 Finland Quansight LLC AustinTX United States Ultrasound Imaging Mayo Clinic RochesterMN55902 United States Electrical Engineering Brigham Young University ProvoUT84604 United States Enthought Inc. AustinTX78701 United States Anaconda Inc AustinTX78701 United States BioResource and Agricultural Engineering Department California Polytechnic State University San Luis ObispoCA93407 United States Department of Mathematics University of California Los AngelesCA90025 United States Los Alamos National Laboratory Los AlamosNM87544 United States Independent Researcher Higher School of Economics Myasnitskaya 20 Moscow101000 Russia Independent Researcher Saue Estonia Department of Mechanics and Applied Mathematics Institute of Cybernetics Tallinn Technical University Akadeemia Rd 21 Tallinn Estonia Independent Researcher NY United States Berkeley Institute for Data Science University of California BerkeleyCA94720 United States School of Psychology University of Birmingham Edgbaston BirmighamB15 2TT United Kingdom Division of Biostatistics University of California BerkeleyCA94720 United States WayRay LLC Skolkovo Innovation Center Moscow143026 Russia Australian Nuclear Science and Technology Organisation Locked Bag 2001 Kirrawee DCNSW2232 Australia Institute for Learning and Brain Sciences University of Washington SeattleWA98195 United States College of Information and Computing Sciences University of Massachusetts Amherst AmherstMA01002 United States Berkeley Center for Cosmological Physics University of California BerkeleyCA94720 United States Bruker Biospin Corp. 15 Fortune Drive BillericaMA01821 United States University of Washington SeattleWA98195 United States New Technologies - Research Centre University of West Bohemia Univerzitní 8 Plzeň306 14 Czech Republic Oden Institute for Computational Engineering and Sciences University of Texas at Austin AustinTX7

SciPy is an open source scientific computing library for the Python programming language. SciPy 1.0 was released in late 2017, about 16 years after the original version 0.1 release. SciPy has become a de facto standard for leveraging scientific algorithms in the Python programming language, with more than 600 unique code contributors, thousands of dependent packages, over 100,000 dependent repositories, and millions of downloads per year. This includes usage of SciPy in almost half of all machine learning projects on GitHub, and usage by high profile projects including LIGO gravitational wave analysis and creation of the first-ever image of a black hole (M87). The library includes functionality spanning clustering, Fourier transforms, integration, interpolation, file I/O, linear algebra, image processing, orthogonal distance regression, minimization algorithms, signal processing, sparse matrix handling, computational geometry, and statistics. In this work, we provide an overview of the capabilities and development practices of the SciPy library and highlight some recent technical developments. Copyright © 2019, The Authors. All rights reserved.

关键词： Open source software

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One session of fMRI-Neurofeedback training on motor imagery modulates whole-brain effective connectivity and dynamical complexity

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Cerebral cortex communications 2022年第3期3卷 tgac027页

作者： Eleonora De Filippi Theo Marins Anira Escrichs Matthieu Gilson Jorge Moll Fernanda Tovar-Moll Gustavo Deco Computational Neuroscience Group Center for Brain and Cognition Department of Information and Communication Technologies Universitat Pompeu Fabra Barcelona Carrer de Ramon Trias Fargas 25-27 08005 Barcelona Catalonia Spain. D'Or Institute for Research and Education (IDOR) Rua Diniz Cordeiro 30 Botafogo-Rio de Janeiro 22281-100 Brazil. Post-Graduate Program in Morphological Sciences Institute of Biomedical Sciences Federal University of Rio de Janeiro Citade universitaria da Universidade Federal do Rio de Janeiro 21941-590 Brazil. Institució Catalana de la Recerca i Estudis Avançats (ICREA) Passeig de Lluis Companys 23 08010 Barcelona Catalonia Spain. Department of Neuropsychology Max Planck Institute for human Cognitive and Brain Sciences Stephanstrasse 1a 04103 Leipzig Germany. Turner Institute for Brain and Mental Health Monash University level 5 18 Innovation Walk Clayton Campus. Wellington Road Clayton VIC 3800 Australia.

In the past decade, several studies have shown that Neurofeedback (NFB) by functional magnetic resonance imaging can alter the functional coupling of targeted and non-targeted areas. However, the causal mechanisms underlying these changes remain uncertain. Here, we applied a whole-brain dynamical model to estimate Effective Connectivity (EC) profiles of resting-state data acquired before and immediately after a single-session NFB training for 17 participants who underwent motor imagery NFB training and 16 healthy controls who received sham feedback. Within-group and between-group classification analyses revealed that only for the NFB group it was possible to accurately discriminate between the 2 resting-state sessions. NFB training-related signatures were reflected in a support network of direct connections between areas involved in reward processing and implicit learning, together with regions belonging to the somatomotor, control, attention, and default mode networks, identified through a recursive-feature elimination procedure. By applying a data-driven approach to explore NFB-induced changes in spatiotemporal dynamics, we demonstrated that these regions also showed decreased switching between different brain states (i.e. metastability) only following real NFB training. Overall, our findings contribute to the understanding of NFB impact on the whole brain's structure and function by shedding light on the direct connections between brain areas affected by NFB training.

关键词： motor imagery neurofeedback real-time fMRI whole-brain dynamics whole-brain effective connectivity

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THE CALLING(SM) NETWORK - A GLOBAL WIRELESS communication-SYSTEM

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INTERNATIONAL JOURNAL OF SATELLITE communicationS 1994年第1期12卷 45-61页

作者： TUCK, EF PATTERSON, DP STUART, JR LAWRENCE, MH Calling Communications Corporation. 1900 West Garvey Ave South. Suite 200 West Covina CA 91790 USA. Chairman of Calling Communications Corporation. He is also the Managing Director of Kinship Venture Management Inc. the general partner of Kinship Partners 11 and a General Partner of Boundary the general partner of The Boundary Fund. As a venture capitalist he has founded or participated in founding several telecommunications companies including Calling Communications Corporation Magellan Systems Corporation manufactures of Global Positioning System receivers Applied Digital Access manufacturer of DS-3 test access and network performance monitoring equipment Endgate Technology Corporation specialists in satellite phased array antennas and Poynting Systems Corporation. now a division of Reliance Corporation manufacturers of fibre optic transport equipment. He was a founder of Kebby Microwave Corporation where he invented the first solid-state. frequency-modulated commercial microwave link system. The company was acquired by ITT Corporation where he rose to the position of V.P. and Technical Director of ITT North America Telecommunications Inc. Subsequently he was V.P. of Marketing and Engineering at American Telecommunications Inc. (ATC). He was founding Director of American Telecom Inc. a joint venture between ATC and Fujitsu and has served on more than 20 boards of directors including those of three public companies. He has authored articles on microwave engineering and telephone signalling and was a contributor to Reference Data For Radio Engineers. He is a graduate of the University of Missouri at Rolla where he was later awarded an honorary Professional degree and serves on its Academy of Electrical Engineering. Mr Tuck is a Senior Member of the IEEE a Fellow of the Institution of Engineers (Australia) a Professional Member of the AIAA and a registered professional engineer in three states. More than 25 years of experience in the telecommunications industry where he has been responsibl

There is a very large demand for basic telephone service in developing nations, and remote parts of industrialized nations, which cannot be met by conventional wireline and cellular systems. This is the world's largest unserved market. We describe a system which uses recent advances in active phased arrays, fast-packet switching technology, adaptive routeing, and light spacecraft technology, in part based on the work of the Jet Propulsion Laboratory and on recently-declassified work done on the Strategic Defense Initiative, to make it possible to address this market with a global telephone network based on a large low-Earth-orbit constellation of identical satellites. A telephone utility can use such a network to provide the same modern basic and enhanced telephone services offered by telephone utilities in the urban centres of fully-industrialized nations. Economies of scale permit capital and operating costs per subscriber low enough to provide a service to all subscribers, regardless of location, at prices comparable to the same services in urban areas of industrialized nations, while generating operating profits great enough to attract the capital needed for its construction. The bandwidth needed to support the capacity needed to gain these economies of scale requires that the system use K(alpha)-band frequencies. This choice of frequencies places unusual constraints on the network design, and in particular forces the use of a large number of satellites. Global demand for basic and enhanced telephone service is great enough to support at least three networks of the size described herein. The volume of advanced components, and services such as launch services, required to construct and replace these networks is sufficient to propel certain industries to market leadership positions in the early 21st Century.

关键词： LOW EARTH ORBIT SATELLITE communicationS FAST PACKET SWITCHING EARTH FIXED CELLS ADAPTIVE ROUTEING LIGHT SPACECRAFT K(A) BAND PHASED-ARRAY ANTENNAS

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