检索结果-内蒙古大学图书馆

Impact of DNA-binding position variants on yeast gene expression

Nucleic Acids Research 2009年第21期37卷 6991-7001页

作者： Swamy, Krishna B.S. Cho, Chung-Yi Chiang, Sufeng Tsai, Zing Tsung-Yeh Tsai, Huai-Kuang Institute of Information Science National Yang-Ming University Taiwan Bioinformatics Program Taiwan International Graduate Program National Yang-Ming University Taiwan Institute of Biomedical Informatics National Yang-Ming University Taiwan Research Center for Information Technology Innovation Academia Sinica Taipei 115 Taiwan

Transcription factors (TFs) regulate gene expression by binding to specific binding sites (TFBSs) in gene promoters. TFBS motifs may contain one or more variable positions. Although the prevailing assumption is that nucleotide variants at such positions are functionally equivalent, there is increasing evidence that such variants play a role in regulation of gene expression. In this article, we propose a method for studying the relationship between the expression of target genes and nucleotide variants in TFBS motifs at a genome-wide scale in Saccharomyces cerevisiae, especially the combinatorial effects of variants at two positions. Our analysis shows that nucleotide variations in more than one-third of variable positions and in 20% of dependent position pairs are highly correlated to gene expression. We define such positions as 'functional'. However, some positions are only functional as dependent pairs, but not individually. In addition, a significant proportion of the functional positions have been well conserved across all yeast-related species studied. We also find that some positions require the presence of co-occurring TFs, while others maintain their functionality in the absence of a co-occurring TF. Our analysis supports the importance of nucleotide variants at variable positions of TFBSs in gene regulation. © The Author(s) 2009. Published by Oxford University Press.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Trust-building mechanisms and knowledge sharing in virtual communities

Trust-building mechanisms and knowledge sharing in virtual c...

引用

9th International Conference on Electronic Business, ICEB 2009

作者： Chang, Chun-Ming Yen, Chia-Hui Cheng, Hsiang-Lan Department of Tourism Information Aletheia University Taiwan Department and Graduate Program in International Business Ming Chuan University Taiwan National Kaohsiung First University of Science and Technology Taiwan

Although trust has received much intention in the virtual communities (VCs) literature, few studies have been conducted to examine how trust develops in VCs. Drawing from prior literature on trust and knowledge sharing, a research model for understanding the antecedents of trust and the role of trust in VCs is presented. Data was collected from 324 members of a technical virtual community to test the model. The results help in identifying how the factors fall into three trust-building mechanisms build trust in the context VCs. The study discusses the theoretical and managerial implications of this study and proposes several future research directions.

关键词： Virtual reality

来源：评论

学校读者我要写书评

暂无评论

Design an empathic virtual human to encourage and persuade learners in e-learning systems

Design an empathic virtual human to encourage and persuade l...

引用

1st ACM International Workshop on Multimedia Technologies for Distance Learning, MTDL 2009, Co-located with the 2009 ACM International Conference on Multimedia, MM'09

作者： Wang, Chin-Yeh Chen, Gwo-Dong Liu, Chen-Chung Liu, Baw-Jhiune Taiwan e-Learning and Digital Archives Program Office National Central University Taiwan Department of Computer Science and Information Engineering National Central University Taiwan Graduate Institute of Network Learning Technology National Central University Taiwan Department of Computer Science and Engineering Yuan-Ze University Taiwan

ISBN: (纸本)9781605587578

Studies indicate that making learners feel good is important only minor to clear knowledge transformation. Many studies have tried to use virtual humans as a part of interface in learning systems to increase the effect of instructions. Based on social interaction and pedagogical theories, many e-learning systems use animated films or virtual reality to boost human-computer engagement and ease their negative emotions. However, affective learning systems still need much research to improve their functionalities and usability. This study proposed a convenient approach to develop an emotionally interactive learning system;learners can express their emotions by mouse-clicking while learning. A virtual human was created to empathically react to learners in proactive and reactive ways to encourage and persuade them into persistent learning and help achieve their goals. Experimental results show that, averagely, subjects can tell virtual human's emotions and agree to its empathic reactions. Persuasion conducted by virtual human could not increase subjects' learning time, but could significantly increase their completion rate of exercises. Copyright 2009 ACM.

关键词： Learning systems

来源：评论

学校读者我要写书评

暂无评论

Micromachined ultrasonic transducer using piezoelectric PVDF film to measure the mechanical properties of bio cells

Micromachined ultrasonic transducer using piezoelectric PVDF...

引用

IEEE SENSORS

作者： Minhyun Jung Man Geun Kim Jong-Hyun Lee School of Information and Mechatronics Gwangju Institute of Science and Technology Gwangju South Korea Graduate-program of Medical System Engineering Gwangju Institute of Science and Technology Gwangju South Korea

We proposed a new method to measure the frequency-dependent attenuation of bio cells using piezoelectric ultrasonic transducer. The polyvinylidene fluoride (PVDF) polymer was employed as piezoelectric material to take an advantage of its low acoustic impedance (2.7 Mrayl) so that the transmission of acoustic power will be improved by impedance matching with that of liquid medium. The thickness of PVDF film is 110 ¿m and the resonance frequency of the 1 st thickness mode is 8.7 MHz. In order to characterize the fabricated ultrasonic transducer, a transducer and an acoustic wave reflector were positioned face to face. The output voltage for reflected transmitted ultrasonic wave was measured with impulse method and was transformed into the Round Trip Insertion Loss (RTIL) where the dominant frequency ranges from 5 MHz to 9 MHz.

关键词： Ultrasonic transducers Piezoelectric films Mechanical variables measurement Ultrasonic variables measurement Mechanical factors Acoustic measurements Frequency measurement Attenuation measurement Polymers Piezoelectric materials

来源：评论

学校读者我要写书评

暂无评论

Probabilistic structure from sound

引用

Advanced Robotics 2009年第12-13期23卷 1687-1702页

作者： Wang, Chieh-Chih Lin, Chi-Hao Hu, Jwu-Sheng Department of Computer Science and Information Engineering Graduate Institute of Networking and Multimedia National Taiwan University Taipei 10617 Taiwan Intelligent Robotics Program of Industrial Technology Research Institute Department of Electrical and Control Engineering National Chiao Tung University HsinChu 310 Taiwan

Auditory perception is one of the most important functions for robotics applications. Microphone arrays are widely used for auditory perception in which the spatial structure of microphones is usually known. In practice, microphone array calibration can be tedious and other devices or means are required. The structure from sound (SFS) approach addresses the problem of simultaneously localizing a set of microphones and a set of acoustic events that provides a great flexibility to calibrate different setups of microphone arrays. However, the existing method does not take measurement uncertainty into account and does not provide uncertainty estimates of the SFS results. In this paper, we propose a probabilistic structure from sound (PSFS) approach using the unscented transform in which the uncertainties of the PSFS results are also available. In addition, a probabilistic sound source localization approach using the PSFS results is provided to improve sound source localization accuracy. The ample results of simulation and experiments using low-cost, off-the-shelf microphones demonstrate the feasibility and performance of the proposed PSFS approach. © 2009 VSP.

关键词： Microphone array

来源：评论

学校读者我要写书评

暂无评论

Dielectric constant at x -band microwave frequencies for multiferroic BiFeO3 thin films

引用

Journal of Applied Physics 2009年第7期105卷

作者： Abdul Ahad, Faris B. Hung, D.S. Yao, Y.D. Lee, S.F. Tu, C.S. Wang, T.H. Chen, Y.Y. Fu, Y.P. Institute of Physics and Nano Science and Technology Program Taiwan International Graduate Program Academia Sinica Taipei 115 Taiwan Department of Engineering and System Science NTHU Hsinchu 300 Taiwan Department of Information and Telecommunication Engineering Ming Chuan University Taipei 111 Taiwan Department of Materials Engineering Tatung University Taipei 104 Taiwan Department of Graduate Institute of Applied Science and Engineering Fu Jen University Taipei 242 Taiwan Department of Materials Science and Engineering National Dong Hwa University Hualien 974 Taiwan

The magnetic-induced dielectric responses of BiFeO3 (BFO) thin films were measured at the X -band microwave frequency ranged from 7 to 12.5 GHz. The measurement was given initially by a high-precision cavity microwave resonator without magnetic field. Both the real and imaginary parts of the permittivity showed its dielectric property as a function of the measuring frequency. The X -band dielectric responses of the BFO thin film were then measured by a controlled magnetic field at room temperature. The data demonstrated up to 2.2% dielectric tunability by using only 3.46 kOe magnetic field at TE107 mode (9.97705 GHz). © 2009 American Institute of Physics.

关键词： Magnetic fields

来源：评论

学校读者我要写书评

暂无评论

Self-improving empathy learning

Self-improving empathy learning

引用

5th International Conference on information technology and Applications, ICITA 2008

作者： Legaspi, Roberto Kurihara, Satoshi Fukui, Ken-Ichi Moriyama, Koichi Numao, Masayuki Program Ministry of Education Culture Sports Science and Technology Japan Division of Intelligent Systems Science Institute of Scientific and Industrial Research Osaka University 8-1 Mihogaoka Ibaraki Osaka 567-0047 Japan Graduate School of Information Science and Technology Osaka University 1-5 Yamadaoka Suita Osaka 565-0871 Japan

ISBN: (纸本)9780980326727

Studies have emphasized that empathy is a learnable skill that can be developed through learning from experience. Applying this in the context of human-system interaction, an empathic system is one that automatically acquires an initial knowledge of empathy that is permitted to be incomplete, hence inaccurate and imperfect, but improves this knowledge each time it learns from its interactions with the user until its empathy knowledge matures over time. This paper posits a self-improving empathy learning for user-centric systems. Due to the nature of the problem that centers on incremental experiential learning, this problem becomes a machine learning application. We highlight the need for machine learning techniques that can address the challenge of an empathic system self-improving its empathy model efficiently online from incomplete knowledge through the intelligent use of its experiences. We suggest that the community position itself to investigate empathic reasoning in the context of a self-learning system with machine learning at the core of its AI.

关键词： Computer aided instruction

来源：评论

学校读者我要写书评

暂无评论

Fuzzy Fusion for Affective State Assessment in Distance Learning Based on Image Detection

Fuzzy Fusion for Affective State Assessment in Distance Lear...

引用

2008 International Conference on Audio，Language and Image Processing(2008国际声音、语言、图像过程大会)

作者： Kuoan Hwang Chiahao Yang Department of Computer Science and Information Engineering & Graduate Institute of Networking and Co Graduate Institute of Informatics Doctoral program Chaoyang University of Technology

Distance learning is a learning style that can overcome the limitation of time and space. Because of the distance, teachers can not handle the student's learning situation, and they do not know whether the student is attentive, drowsy or absent. If teachers can know the student's affective state, they can overcome the difficult. The research applies the image recognition technologies to capture the face images of students when they are learning and analyzes their face features to evaluate the student's affective state by Fuzzy Integral. Finally, teachers can monitor the student's behavior by the detection results on the system interface.

关键词： Distance learning Skin Computers Distance measurement Face Image color analysis Education

来源：评论

学校读者我要写书评

暂无评论

Attentiveness Assessment in Learning Based on Fuzzy Logic Analysis

Attentiveness Assessment in Learning Based on Fuzzy Logic An...

引用

International Conference on Intelligent Systems Design and Applications (ISDA)

作者： Kuo-An Hwang Chia-Hao Yang Department of Computer Science and Information Engineering & Graduate Institute of Networking and CommunicationEngineering ChaoYang University of Technology Taiwan Graduate Institute of Informatics Doctoral program ChaoYang University of Technology Taiwan

Learner attention affects learning efficiency. However, in many classes, teachers cannot assess the degree of attention of every student. When a teacher is capable of addressing inattentive students immediately, he can avoid situations in which students are inattentive. Many studies have analyzed student attentiveness by the applying of image detection technologies. If this mechanism can be applied to in-class learning, it will help teachers keep students attentive, and reduce teacher load during class. This study mainly applies fuzzy logic analysis of student facial images when participating in class. Applying fuzzy logic can prevent erroneous judgments associated with a single term, and help teachers deal with student attentiveness.

关键词： Fuzzy logic Face detection Image analysis Image color analysis Education Eyes Design engineering Chaotic communication Image processing Face recognition

来源：评论

学校读者我要写书评

暂无评论

Comparisons of classifier algorithms: Bayesian network, C4.5, decision forest and NBTree for Course Registration Planning model of undergraduate students

Comparisons of classifier algorithms: Bayesian network, C4.5...

引用

IEEE International Conference on Systems, Man and Cybernetics

作者： Pathom Pumpuang Anongnart Srivihok Prasong Praneetpolgrang Department of Computer Science Faculty of Science Kasetsart University Bangkok Thailand Master of Science Program in Information Technology Graduate School Sripatum University Bangkok Thailand

The success rate of computer science and engineering students in private universities are not high. It is helpful to find the model to assist students in registration planning. The objective of this research is to propose the classifier algorithm for building course registration planning model (CRPM) from historical dataset. The algorithm is selected by comparing performances of four classifiers include Bayesian network, C4.5, Decision Forest and NBTree. The dataset were obtained from student enrollments including grade point average (GPA) and grades of undergraduate students whose majors were computer science or computer engineering. These dataset included grades in each subject of first and second year students from a private university in Thailand. Results showed that NBTree seemed to be the best of four classifiers which had highest prediction power. NBTree was used to generate CRP model which can be used to predict student class of GPA and consider student course sequences for registration planning.

关键词： Bayesian methods Computer science Predictive models Data mining Decision trees Noise cancellation information technology Data analysis Computer science education Path planning

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：