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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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AN EQUIVALENCY CONDITION OF NONSINGULARITY IN NONLINEAR SEMIDEFINITE programMING

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Journal of systems Science & Complexity 2010年第4期23卷 822-829页

作者： Chengjin LI Wenyu SUN Raimundo J. B. de SAMPAIO School of Mathematical Sciences Nanjing Normal and Computer Science Fujian Normal University Wenyu SUN University Nanjing 210046 China School of Mathematics Fuzhou 350007 China School of Mathematical Sciences Nanjing Normal University Nanjing 210046 China Pontifical Catholic University of Parana ( PUCPR) Graduate Program in Production and Systems Engineering (PPGEPS) CEP 81611-970 Curitiba Parana Brazil

In this paper,an equivalency condition of nonsingularity in nonlinear semidefinite programming,which can be viewed as a generalization of the equivalency condition of nonsingularity for linearsemidefinite programming,... 详细信息

关键词： Equivalency condition of nonsingularity nonlinear semidefinite programming semidefinite programming.

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Fuzzy model and particle swarm optimization for nonlinear identification of a Chua's oscillator

Fuzzy model and particle swarm optimization for nonlinear id...

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2007 IEEE International Conference on Fuzzy systems, FUZZY

作者： Araujo, Ernesto Dos Santos Coelho, Leandro IEEE Cx.P. 515 12.227-010 Sao Jose dos Campos SP Brazil Production and Systems Engineering Graduate Program PPGEPS Pontifical Catholic University of Parana Imaculada Conceicao 1155 80.215-901 Curitiba PR Brazil

ISBN: (纸本)1424412102

The identification of a nonlinear system with chaotic behavior denoted Chua's oscillator by using fuzzy models intertwined with particle swarm optimization (PSO) method is presented. This hybrid approach is applied to experimental data generated by an inductorless Chua's circuit that consists of an electronic chaotic oscillator. Chua's circuit has been used as a test platform by various scientific and engineering communities related to the study of chaos due its great potencial in technological applications, for instance, telecommunications, cryptography and physics. Fuzzy set theory has been evolved as a powerful modeling tool that can cope with uncertainties and nonlinearities in modeling and identification procedures. The identification of a optimized fuzzy model Takagi-Sugeno (T-S) fuzzy model involves two primary tasks: parameter tuning and structure optimization. The premise part of production rules is optimized here by using the particle swarm optimization method. In turn, least mean squares technique is applied to the consequent part of a T-S fuzzy model. Results indicate PSO method and Least Mean Square technique succeeded in constructing a T-S fuzzy model when dealing with chaotic dynamics obtained through experimental data supplied by inductorless Chua's electronic circuit. © 2007 IEEE.

关键词： Fuzzy set theory

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Fuzzy Model and Particle Swarm Optimization for Nonlinear Identification of a Chua's Oscillator

Fuzzy Model and Particle Swarm Optimization for Nonlinear Id...

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IEEE International Conference on Fuzzy systems (FUZZ-IEEE)

作者： Ernesto Araujo Leandro dos Santos Coelho Instituto Nacional de Pesquisas Espaciais (INPE) Integration and Testing Laboratory Brazil Production and Systems Engineering Graduate Program PPGEPS Pontifical Catholic University of Paraná Curitiba Pernambuco Brazil

关键词： Particle swarm optimization Oscillators Chaos Circuit testing Nonlinear systems Fuzzy systems Hybrid power systems Power engineering and energy Cryptography Physics

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Combining of chaotic differential evolution and quadratic programming for economic dispatch optimization with valve-point effect (vol 21, pg 989, 2006)

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IEEE TRANSACTIONS ON POWER systems 2006年第3期21卷 1465-1465页

作者： dos Santos Coelho, Leandro Cocco Mariani, Viviana Production and Systems Engineering Graduate Program Automation and Systems Laboratory PUCPRJCCET/PPGEPSILAS Pontifical Catholic University of Paraná 802 15-901 Curitiba Paraná Brazil Mechanical Engineering Graduate Program PUCPRJCCETIPPGEM Pontifical Catholic University of Paraná 802 15-901 Curitiba Paraná Brazil

Evolutionary algorithms are heuristic methods that have yielded promising results for solving nonlinear, nondifferentiable, and multi-modal optimization problems in the power systems area. The differential evolution (DE) algorithm is an evolutionary algorithm that uses a rather greedy and less stochastic approach to problem solving than do classical evolutionary algorithms, such as genetic algorithms, evolutionary programming, and evolution strategies. DE also incorporates an efficient way of self-adapting mutation using small populations. The potentialities of DE are its simple structure, easy use, convergence property, quality of solution, and robustness. This paper proposes a new approach for solving economic load dispatch problems with valve-point effect. The proposed method combines the DE algorithm with the generator of chaos sequences and sequential quadratic programming (SQP) technique to optimize the performance of economic dispatch problems. The DE with chaos sequences is the global optimizer, and the SQP is used to fine-tune the DE run in a sequential manner. The combined methodology and its variants are validated for two test systems consisting of 13 and 40 thermal units whose incremental fuel cost function takes into account the valve-point loading effects. The proposed combined method outperforms other state-of-the-art algorithms in solving load dispatch problems with the valve-point effect. [ABSTRACT FROM AUTHOR]

关键词： Chaotic sequences differential evolution (DE) economic dispatch evolutionary algorithms optimization power generation valve-point effect

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Maintenance integration in a control-monitoring architecture based on Petri net with objects. Application to a flexible manufacturing system

Maintenance integration in a control-monitoring architecture...

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2006 IEEE Conference on Emerging Technologies and Factory Automation, ETFA

作者： Loures, E. Rocha Busetti De Paula, M.A. Pascal, J.-C. Graduate Program in Production System Engineering PUCPR Curitiba Brazil Laboratory for Analysis and Architecture of Systems LAAS/CNRS Toulouse France

ISBN: (纸本)1424406811

The problem of failure occurrence in flexible manufacturing systems (FMS) tends to increase according to their complexity leading to time-consuming tasks as the localisation and repairing. The occurrence of failures during the exploitation stage can deeply modify the FMS performances or its availability. We want to investigate the maintenance integration into a control-monitoring framework, from the control system's early design stage to the maintenance policies execution, so as to improve production time and minimize unplanned costly breakdowns of FMS. This paper proposes a modular and hierarchic control-monitoring-maintenance architecture (CMM) for FMS based on Petri nets with objects (PNO). These efforts acts as a basis for the control architecture of a robot-driven flexible cell, connected to the Ethernet-TCP/IP. © 2006 IEEE.

关键词： Flexible manufacturing systems

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Chaotic differential evolution applied to electromagnetics optimization

Chaotic differential evolution applied to electromagnetics o...

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12th Biennial IEEE Conference on Electromagnetic Field Computation, CEFC 2006

作者： Dos Santos Coelho, Leandro Mariani, Viviana Cocco Production and Systems Engineering Graduate Program Automation and Systems Laboratory Pontifical Catholic University of Paraná Imaculada Conceicao 1155 80215-901 Curitiba Brazil Pontifical Catholic University of Paraná Mechanical Engineering Graduate Program PUCPR/PPGEM Imaculada Conceicao 1155 80215-901 Curitiba Brazil

ISBN: (纸本)1424403200

This work presents a new global optimization algorithm based on differential evolution (DE) method and DE combined with chaotic sequences (DEC) given by logistic map. In this paper, the optimal shape design of Loney's solenoids benchmark problem is carried out by DE and DEC algorithms. The results of DE and DEC approaches are also investigated and their performance compared with those reported in the literature. © 2006 IEEE.

关键词： Chaos theory

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Use of cultural particle swarm optimization for Loney's Solenoids design

Use of cultural particle swarm optimization for Loney's Sole...

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12th Biennial IEEE Conference on Electromagnetic Field Computation, CEFC 2006

作者： Coelho, Leandro Dos Santos Mariani, Viviana Cocco Pontifical Catholic University of Paraná Production and Systems Engineering Graduate Program Automation and Systems Laboratory PUCPR/PPGEPS/LAS Imaculada Conceicao 1155 80215-901 Curitiba Brazil Pontifical Catholic University of Paraná Mechanical Engineering Graduate Program PUCPR/PPGEM Imaculada Conceiçao 1155 80215-901 Curitiba Brazil

ISBN: (纸本)1424403200

This work presents the use of particle swarm optimization (PSO) techniques with the particles' population space based on normative knowledge of cultural algorithms (CA). In this work, the optimal shape design of Loney's solenoids benchmark problem is carried out by PSO, PSO-CA, Gaussian PSO and Gaussian PSO-CA approaches. ©2006 IEEE.

关键词： Solenoids

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An efficient particle swarm optimization approach based on cultural algorithm applied to mechanical design

An efficient particle swarm optimization approach based on c...

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2006 IEEE Congress on Evolutionary Computation, CEC 2006

作者： Dos Coelho, Leandro Santos Mariani, Viviana Coceo Pontifical Catholic University of Paraná Production and Systems Eng. Graduate Program Automation and Systems Laboratory Imaculada Conceicao 1155 80215-901 Curitiba Parana Brazil Pontifical Catholic University of Paraná Mechanical Engineering Graduate Program Imaculada Conceicao 1155 80215-901 Curitiba Parana Brazil

ISBN: (纸本)0780394879

Particle swarm optimization (PSO) is a population-based swarm intelligence algorithm driven by the simulation of a social psychological metaphor instead of the survival of the fittest individual. Based on the swarm intelligence theory, this paper discusses the use of PSO approaches using an operator and based on the Gaussian probability distribution function as a population space of a cultural algorithm, called cultural Gaussian PSO (GPSO-CA). Cultural algorithms are mechanisms that incorporate domain knowledge obtained during the evolutionary process, which increase the efficiency of the search process. These approaches are employed in a well-studied continuous optimization problem of mechanical engineering design. © 2006 IEEE.

关键词： Global optimization

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