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Phosphors as Sensors for Radiation-Induced Displacement Damage

MRS Online Proceedings Library 2012年第1期1471卷 68-74页

作者： Gollub, S. L. Harl, R. R. Weeden-Wright, S. L. Rogers, B. R. Walker, D. G. Interdisciplinary Graduate Program in Materials Science Vanderbilt University USA Department of Chemical and Biomolecular Engineering Vanderbilt University USA Department of Electrical Engineering Vanderbilt University USA Department of Mechanical Engineering Vanderbilt University USA

The radiation-induced displacement damage in yttrium borate (YBO3) is studied under X-ray, proton, and alpha irradiation. The photoluminescence (PL) was tested before and after irradiation to determine whether damage occurred and whether it could be queried by examining the PL spectrum. Two different dopants (cerium and europium) were used to activate the phosphor because each provides not only a different spectral signature but also a different mechanism for altering the spectrum between the pre- and post-PL measurements. X-rays, being primarily ionizing radiation, did not show any significant change between the pre and post measurements. We expected protons and alphas to damage the crystal structure, evidence of which could be seen in the change in the spectra before and after irradiation. However, we found no change under alpha exposure (3.6 × 1010 particles/cm2) and a significant change after proton exposure (5 × 1015 particles/cm2). While the material appears to be sensitive to protons, we cannot rule out its sensitivity to alphas because the alpha fluence may be too low to show an effect. This result provides strong indication that our materials are being damaged by particle radiation and that the radiation effects can be quantified.

关键词： luminescence radiation effects optical properties

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Graphene Quantum Dots: Facile Synthetic Method for Pristine Graphene Quantum Dots and Graphene Oxide Quantum Dots: Origin of Blue and Green Luminescence (Adv. Mater. 27/2013)

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Advanced Materials 2013年第27期25卷

作者： Fei Liu Min‐Ho Jang Hyun Dong Ha Je‐Hyung Kim Yong‐Hoon Cho Tae Seok Seo Department of Chemical and Biomolecular Engineering (BK21 program) and Institute for the BioCentury Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak‐ro Yuseong‐gu Daejeon 305‐701 Republic of Korea Department of Physics Graduate School of Nanoscience & Technology (WCU) and Graphene Research Center of KI for the NanoCentury Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak‐ro Yuseong‐gu Daejeon 305‐701 Republic of Korea

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31st Annual Meeting and Associated programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016

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J Immunother Cancer 2016年第SUPPL 1期4卷 1-1页

作者： Andreas Lundqvist Vincent van Hoef Xiaonan Zhang Erik Wennerberg Julie Lorent Kristina Witt Laia Masvidal Sanz Shuo Liang Shannon Murray Ola Larsson Rolf Kiessling Yumeng Mao John-William Sidhom Catherine A. Bessell Jonathan Havel Jonathan Schneck Timothy A. Chan Eliot Sachsenmeier David Woods Anders Berglund Rupal Ramakrishnan Andressa Sodre Jeffrey Weber Roberta Zappasodi Yanyun Li Jingjing Qi Philip Wong Cynthia Sirard Michael Postow Walter Newman Henry Koon Vamsidhar Velcheti Margaret K. Callahan Jedd D. Wolchok Taha Merghoub Lawrence G. Lum Minsig Choi Archana Thakur Abhinav Deol Gregory Dyson Anthony Shields Cara Haymaker Marc Uemura Ravi Murthy Marihella James Daqing Wang Julie Brevard Catherine Monaghan Suzanne Swann James Geib Mark Cornfeld Srinivas Chunduru Sudhir Agrawal Cassian Yee Jennifer Wargo Sapna P. Patel Rodabe Amaria Hussein Tawbi Isabella Glitza Scott Woodman Wen-Jen Hwu Michael A. Davies Patrick Hwu Willem W. Overwijk Chantale Bernatchez Adi Diab Erminia Massarelli Neil H. Segal Vincent Ribrag Ignacio Melero Tara C. Gangadhar Walter Urba Dirk Schadendorf Robert L. Ferris Roch Houot Franck Morschhauser Theodore Logan Jason J. Luke William Sharfman Fabrice Barlesi Patrick A. Ott Laura Mansi Shivaani Kummar Gilles Salles Cecilia Carpio Roland Meier Suba Krishnan Dan McDonald Matthew Maurer Xuemin Gu Jaclyn Neely Satyendra Suryawanshi Ronald Levy Nikhil Khushalani Jennifer Wu Jinyu Zhang Fahmin Basher Mark Rubinstein Mark Bucsek Guanxi Qiao Cameron MacDonald Bonnie Hylander Elizabeth Repasky Shilpak Chatterjee Anusara Daenthanasanmak Paramita Chakraborty Kyle Toth Megan Meek Elizabeth Garrett-Mayer Michael Nishimura Chrystal Paulos Craig Beeson Xuezhong Yu Shikhar Mehrotra Fei Zhao Kathy Evans Christine Xiao Alisha Holtzhausen Brent A. Hanks Nicole Scharping Ashley V. Menk Rebecca Moreci Ryan Whetstone Rebekah Dadey Simon Watkins Robert Ferris Greg M. Delgoffe Jonathan Peled Sean Devlin Anna Staffas Melissa Lumish Kori Porosnicu Rodriguez Katya Ahr Miguel Perales Sergio Giralt Ying Taur Eric Pam Karolinska Institutet Stockholm Stockholms Lan Sweden Weill Cornell Medical College New York NY USA Nova Southeastern University Cell Therapy Institute Fort Lauderdale FL USA Johns Hopkins University School of Medicine Baltimore MD USA Immunology Program Johns Hopkins University School of Medicine Columbia MD USA Memorial Sloan Kettering Cancer Center New York NY USA Johns Hopkins Medical Institute Baltimore MD USA University of Rochester Monrovia MD USA NYU Langone Medical Center New York NY USA H. Lee Moffitt Cancer Center Tampa FL USA Ludwig Collaborative Laboratory Memorial Sloan Kettering Cancer Center New York NY USA Immune Monitoring Core Facility Memorial Sloan Kettering Cancer Center New York NY USA Leap Therapeutics Cambridge MA USA Department of Medicine Memorial Sloan Kettering Cancer Center New York NY USA Case Western Reserve University Cleveland OH USA Cleveland Clinic Main Campus Cleveland OH USA University of Virginia Cancer Center Charlottesville VA USA Stony Brook University Medical Center Stony Brook NY USA Karmanos Cancer Institute Detroit MI USA University of Texas MD Anderson Cancer Center Houston TX USA Idera Pharmaceuticals Inc. Cambridge MA USA Institut Gustave Roussy Villejuif Ile-de-France France Center for Applied Medical Research (CIMA) University of Navarra Pamplona Navarra Spain University of Pennsylvania Philadelphia PA USA Earle A. Chiles Research Institute Providence Cancer Center Portland OR USA Universitätsklinikum Essen Essen Nordrhein-Westfalen Germany University of Pittsburgh Pittsburgh PA USA CHU Rennes Service Hématologie Clinique and INSERM 0203 Unité d’Investigation Clinique Rennes Bretagne France Centre Hospitalier Régional Universitaire de Lille Lille Nord-Pas-de-Calais France Simon Cancer Center Indiana University Indianapolis IN USA University of Chicago School of Medicine Chicago IL USA Johns Hopkins University School of Medicine Lutherville MD USA Multidisciplinary Oncology and Therapeuti

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P-175: Profile of Heterostructured Host for Phosphorescent OLED and its Application to the White Lighting Devices with Low Driving Voltage

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SID Symposium Digest of Technical Papers 2012年第1期42卷

作者： Woo Jin Hyun O. Ok Park Byung Doo Chin Department of Chemical and Biomolecular Engineering (BK21 Graduate Program) Korea Advanced Institute of Science and Technology Daejeon Republic of Korea Department of Polymer Science and Engineering Dankook University Yongin Gyeonggi Republic of Korea

The electrophosphorescent OLED with heterostructured (mixed) light emission layer was characterized. Base on the best combination profile of mixed emitter obtained, we have fabricated the white OLEDs, where the selective cross-patterning technique was employed for the spatial variation of emitting layer thickness. The corresponding lower driving voltage and stable color characteristics were investigated.

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P-175: Profile of heterostructured host for phosphorescent OLED and its application to the white lighting devices with low driving voltage

P-175: Profile of heterostructured host for phosphorescent O...

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作者： Hyun, Woo Jin Park, O. Ok Chin, Byung Doo Department of Chemical and Biomolecular Engineering BK21 Graduate Program Korea Advanced Institute of Science and Technology Daejeon Korea Republic of Department of Polymer Science and Engineering Dankook University Yongin Gyeonggi Korea Republic of

关键词： Phosphorescence

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A new immunoassay platform on a microchip utilizing yeast surface display and impedance flow cytometry

A new immunoassay platform on a microchip utilizing yeast su...

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14th International Conference on Miniaturized Systems for Chemistry and Life sciences 2010, MicroTAS 2010

作者： Wang, Jing Guo, Yongchao Chan, Kwok-Lun Hsing, I-Ming Bioengineering Graduate Program Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong Department of Chemical and Biomolecular Engineering Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong

ISBN: (纸本)9781618390622

We report an ultrasensitive immunoassay method by directly counting genetically-engineered yeast cells bound with target analytes. This technology is shown to be compatible with conventional and microchip-based flow cytometry systems. In particular the microchip-based systems were developed by impedance and resistive pulse measurement for cell counting. This yeast surface display based cell counting immunoassay (abbreviated as YSD-CCI) provides a detection limit of 0.2 ng/mL, which is about 80 times higher than that of the yeast-based ELISA. This new platform offers a strategy for multiplexed and high throughput screening of bio-analytes, and holds promises for implementation on a microchip for point-of-care applications.

关键词： Flow cytometry

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Synthesis of Gold Nano‐hexapods with Controllable Arm Lengths and Their Tunable Optical Properties†

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Angewandte Chemie 2011年第28期123卷

作者： Do Youb Kim Taekyung Yu Eun Chul Cho Yanyun Ma O Ok Park Younan Xia Department of Biomedical Engineering Washington University Saint Louis MO 63130 (USA) Department of Chemical and Biomolecular Engineering (BK21 graduate program) Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak‐ro Yuseong‐gu Daejeon 305‐701 (Korea)

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A new signal-on electrochemistry-based detection platform for DNA and polymerase enzyme on a microchip without probe immobilization chemistry

A new signal-on electrochemistry-based detection platform fo...

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14th International Conference on Miniaturized Systems for Chemistry and Life sciences 2010, MicroTAS 2010

作者： Luo, Xiaoteng Hsing, I.-Ming Bioengineering Graduate Program Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong Department of Chemical and Biomolecular Engineering Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong

ISBN: (纸本)9781618390622

We report a new DNA and polymerase detection method that utilizes the competition between a ferrocene-labeled PNA probe and the target DNA or a polymerase-elongated DNA primer to hybridize with a DNA probe/template. Due to the electrostatic interaction between the negative DNA backbones and a negatively-charged electrode, the results of the competition were reflected in the electrochemical signal of ferrocene, which was used to determine the presence of the target DNA or the DNA polymerase. This detection technology is simple, fast and more reliable compared to previously reported signal-off detection schemes, which make it a promising candidate for point-of-care applications.

关键词： DNA

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Platinum Concave Nanocubes with High‐Index Facets and Their Enhanced Activity for Oxygen Reduction Reaction†

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Angewandte Chemie 2011年第12期123卷

作者： Taekyung Yu Do Youb Kim Hui Zhang Younan Xia Department of Biomedical Engineering Washington University Saint Louis MO 63130 (USA) Department of Chemical and Biomolecular Engineering (BK21 graduate program) Korea Advanced Institute of Science and Technology (KAIST) 335 Gwahangro Yuseong‐gu Daejeon 305‐701 (Korea) State Key Laboratory of Silicon Materials and Department of Materials Science and Engineering Zhejiang University Hangzhou Zhejiang 310027 (People's Republic of China)

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Back Cover: Enhancement of Donor–Acceptor Polymer Bulk Heterojunction Solar Cell Power Conversion Efficiencies by Addition of Au Nanoparticles (Angew. Chem. Int. Ed. 24/2011)

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Angewandte Chemie International Edition 2011年第24期50卷

作者： Dong Hwan Wang Do Youb Kim Kyeong Woo Choi Dr. Jung Hwa Seo Dr. Sang Hyuk Im Prof. Jong Hyeok Park Prof. O Ok Park Prof. Alan J. Heeger Center for Polymers and Organic Solids University of California at Santa Barbara Santa Barbara CA 93106 (USA) Fax: (+1) 805-893-4755 Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology (BK 21 Graduate Program) 373-1 Guseong-dong Yuseong-gu Daejeon 305-701 (Republic of Korea) Fax: (+82) 42-350-3910 KRICT-RPFL Global Research Laboratory Advanced Materials Division Korea Research Institute of Chemical Technology Daejeon (Republic of Korea) School of Chemical Engineering and SKKU Advanced Institute of Nanotechnology (SAINT) Sungkyunkwan University Suwon 440-746 (Republic of Korea) Fax: (+82) 31-290-7272 Jong Hyeok Park School of Chemical Engineering and SKKU Advanced Institute of Nanotechnology (SAINT) Sungkyunkwan University Suwon 440-746 (Republic of Korea) Fax: (+82) 31-290-7272 O Ok Park Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology (BK 21 Graduate Program) 373-1 Guseong-dong Yuseong-gu Daejeon 305-701 (Republic of Korea) Fax: (+82) 42-350-3910 Alan J. Heeger Center for Polymers and Organic Solids University of California at Santa Barbara Santa Barbara CA 93106 (USA) Fax: (+1) 805-893-4755

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