The face of a humanoid robot can affect the user experience, and the detection of face preference is particularly important. Preference detection belongs to a branch of emotion recognition that has received much atten...
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brain-computerinterfaces (BCIs) enable direct communication between the brain and external devices. This review highlights the core decoding algorithms that enable multimodal BCIs, including a dissection of the eleme...
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Spiking Neural Networks (SNNs) are promising for low-power computation due to their event-driven mechanism but often suffer from lower accuracy compared to Artificial Neural Networks (ANNs). ANN-to-SNN knowledge disti...
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Spiking Neural Networks (SNNs) are promising for low-power computation due to their event-driven mechanism but often suffer from lower accuracy compared to Artificial Neural Networks (ANNs). ANN-to-SNN knowledge disti...
brain-computerinterface (BCI) control of multiple rehabilitation robots provides a novel type of human-robot interaction and an important research direction in the field of intelligent rehabilitation. However, most c...
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Research on animal robots utilizing neural electrical stimulation is a significant focus within the field of neuro-control, though precise behavior control remains challenging. This study proposes a parameter-adaptive...
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Metal alloy anode materials with high specific capacity and low voltage have recently gained significant attention due to their excellent electrochemical performance and the ability to suppress dendrite ***,experiment...
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Metal alloy anode materials with high specific capacity and low voltage have recently gained significant attention due to their excellent electrochemical performance and the ability to suppress dendrite ***,experimental investigations of metal alloys can be time-consuming and expensive,often requiring extensive experimental design and *** this study,we developed a machine learning model based on the Crystal Graph Convolutional Neural Network(CGCNN)to screen alloy anode materials for seven battery systems,including lithium(Li),sodium(Na),potassium(K),zinc(Zn),magnesium(Mg),calcium(Ca),and aluminum(Al).We utilized data with tens of thousands of alloy materials from the Materials Project(MP)and Automatic FLOW for Materials Discovery(AFLOW)*** any experimental voltage input,we identified over 30 alloy systems that have been experimentally validated with good ***,we predicted over 100 alloy anodes with low potential and high specific *** hope this work to spur further interest in employing advanced machine learning models for the design of battery materials.
Malfunction of the ventral subiculum(vSub),the main subregion controlling the output connections from the hippocampus,is associated with major depressive disorder(MDD).Although the vSub receives cholinergic innervatio...
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Malfunction of the ventral subiculum(vSub),the main subregion controlling the output connections from the hippocampus,is associated with major depressive disorder(MDD).Although the vSub receives cholinergic innervation from the medial septum and diagonal band of Broca(MSDB),whether and how the MSDB-to-vSub cholinergic circuit is involved in MDD is ***,we found that chronic unpredictable mild stress(CUMS)induced depression-like behaviors with hyperactivation of vSub neurons,measured by c-fos staining and whole-cell patch-clamp *** retrograde and anterograde tracing,we confirmed the dense MSDB cholinergic innervation of the *** addition,transient restraint stress in CUMS increased the level of ACh in the ***,chemogenetic stimulation of this MSDB-vSub innervation in ChAT-Cre mice induced hyperactivation of vSub pyramidal neurons along with depression-like behaviors;and local infusion of atropine,a muscarinic receptor antagonist,into the vSub attenuated the depression-like behaviors induced by chemogenetic stimulation of this pathway and ***,these findings suggest that activating the MSDB-vSub cholinergic pathway induces hyperactivation of vSub pyramidal neurons and depression-like behaviors,revealing a novel circuit underlying vSub pyramidal neuronal hyperactivation and its associated depression.
Fecal microbiota transplantation(FMT)of human fecal samples into germ-free(GF)mice is useful for establishing causal relationships between the gut microbiota and human ***,due to the intrinsic differences between huma...
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Fecal microbiota transplantation(FMT)of human fecal samples into germ-free(GF)mice is useful for establishing causal relationships between the gut microbiota and human ***,due to the intrinsic differences between human and mouse intestines and the different diets of the two organisms,it may not be possible to replicate human phenotypes in mice through FMT;similarly,treatments that are effective in mouse models may not be effective in *** this study,we aimed to identify human gut microbes that undergo significant and consistent changes(i.e.,in relative abundances)after transplantation into GF mice in multiple experimental *** collected 16S rDNA-seq data from four published studies and analyzed the gut microbiota profiles from 1713 human–mouse ***,on average,we found that only 47%of the human gut microbes could be re-established in mice at the species level,among which more than 1/3 underwent significant changes(referred to as“variable taxa”).Most of the human gut microbes that underwent significant changes were consistent across multiple human–mouse pairs and experimental ***,about 1/3 of human samples changed their enterotypes,i.e.,significant changes in their leading species after *** fed with a controlled diet showed a lower enterotype change rate(23.5%)than those fed with a noncontrolled diet(49.0%),suggesting a possible solution for *** of the variable taxa have been reported to be implicated in human diseases,with some recognized as the causative *** results highlight the challenges of using a mouse model to replicate human gut microbiota-associated phenotypes,provide useful information for researchers using mice in gut microbiota studies,and call for additional validations after *** online database named FMT-DB is publicly available at http://***/#/.
Optogenetics technology has greatly promoted the development of neuroscience. Flexible gene manipulation tools and sensitive light activation methods have provided convenience for neural function research. However, th...
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