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Two New α-Glucosidase Inhibitory Depsidones from the Lichen Parmotrema cristiferum (Taylor) Hale

Chemistry and Biodiversity 2023年第3期20卷 e202201213-e202201213页

作者： Do, Thanh-Hung Duong, Thuc-Huy Nguyen Minh An, Tran Vo, Thi-Phi-Giao Do, Van-Mai Nguyen, Ngoc-Hong Sichaem, Jirapast NTT Hi-Tech Institute Nguyen Tat Thanh University Ho Chi Minh City 754000 Viet Nam Department of Chemistry Ho Chi Minh City University of Education 280 An Duong Vuong Street District 5 Ho Chi Minh City 700000 Viet Nam Faculty of Chemical Engineering Industrial University of Ho Chi Minh City Ho Chi Minh City 727000 Viet Nam Faculty of Biology University of Science Vietnam National University Ho Chi Minh City Ho Chi Minh City 700000 Viet Nam Nam Can Tho University Nam Can Tho University Can Tho City 900000 Viet Nam CirTech Institute HUTECH University 475 A Dien Bien Phu Street Binh Thanh District Ho Chi Minh City 717000 Viet Nam Research Unit in Natural Products Chemistry and Bioactivities Faculty of Science and Technology Thammasat University Lampang Campus Lampang 52190 Thailand

A bioactivity-guided investigation of the lichen Parmotrema cristiferum (Taylor) Hale (Parmeliaceae) led to the isolation of two new depsidones, cristifones A and B (1 and 2). The structures of the isolated compounds were identified by spectroscopic methods and comparison with the literature data. Compound 1 showed the initial combined structures of depsidone and depside cores. The two isolated compounds were then evaluated for α-glucosidase inhibition. Compounds 1 and 2 were confirmed as potent, with IC₅₀ values of 21.5 and 18.4 μM, respectively. Compound 2 was a non-competitive inhibitor against α-glucosidase, as indicated by the intersect in the second quadrant of each respective plot. © 2023 Wiley-VHCA AG, Zurich, Switzerland.

关键词： cristifones A and B depside depsidone Parmotrema cristiferum α-glucosidase inhibition

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Multi-phase structure and electrical properties of Bi_(0.5)Li_(0.5)ZrO_3 doping K_(0.48)Na_(0.56)NbO_3 lead-free piezoelectric ceramics

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Journal of Advanced Ceramics 2018年第1期7卷 79-87页

作者： Xiaoyan PENG Boping ZHANG Lifeng ZHU Lei ZHAO Ruixiao MA Bo LIU Xiaodong WANG School of Materials Science and Engineering University of Science and Technology Beijing New Metallurgy Hi-Tech Group Co. Ltd. China Iron & Steel Research Institute Group Hebei Key Lab of Optic-Electronic Information and Materials College of Physics Science & Technology Hebei University

(1–x)K_(0.48)Na_(0.56)NbO_3–xBi_(0.5)Li_(0.5)ZrO_3(KNN–x BLZ, x = 0–0.06) lead-free piezoelectric ceramics were prepared by the conventional solid-state sintering method, and their phase structures and electric properties as well as T_C were systematically investigated. The orthorhombic–tetragonal(O–T) two phases were detected in all(1–x)K_(0.48)Na_(0.56)NbO_3–xBi_(0.5)Li_(0.5)ZrO_3 ceramics at 0.01 ≤ x ≤ 0.05. Due to the appropriate ratio between O phase and T phase(CO/C T= 45/55), high piezoelectric properties of d 33= 239 pC/N, k_p= 34%, and P_r = 25.23 μC/cm^2 were obtained at x = 0.04. Moreover, a high T_C = 348 ℃ was also achieved in KNN–x BLZ ceramic at x = 0.04. These results indicate that (1–x)K_(0.48)Na_(0.56)NbO_3–xBi_(0.5)Li_(0.5)ZrO_3 system is a promising candidate for high-temperature piezoelectric devices.

关键词： lead-free piezoelectric ceramics potassium–sodium niobate (KNN) solid-state sintering multi-phase electrical properties

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Correction: highly reusable nanoporous silver sheet for sensitive SERS detection of pesticides

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The Analyst 2023年第6期148卷 1383页

作者： Huanyu Chi Congcheng Wang Zhien Wang Hongni Zhu Vince St Dollente Mesias Xin Dai Qing Chen Wei Liu Jinqing Huang HKUST-Shenzhen Research Institute No. 9 Yuexing first RD Hi-tech Park Nanshan Shenzhen 518057 China. jqhuang@ust.hk. Department of Chemistry The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China. Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China. Department of Chemistry The University of Hong Kong Pokfulam Road Hong Kong China.

Correction for 'highly reusable nanoporous silver sheet for sensitive SERS detection of pesticides' by Huanyu Chi , , 2020, , 5158-5165, https://***/10.1039/D0AN00999G.

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Effect of drying temperature and storage time on Ocimum gratissimum Linn. leaf essential oil from Central highlands, Vietnam 9

Effect of drying temperature and storage time on Ocimum grat...

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9th International Conference of Materials Processing and Characterization, ICMPC 2019

作者： Anh, Trieu Tuan Duyen, Le Thi Hang, Le My Lam, Tri Duc Bach, Long Giang Nguyen, Duy Chinh Toan, Tran Quoc Faculty of Chemical Engineering and Food Technology Nguyen Tat Thanh University Ho Chi Minh City Viet Nam NTT Hi-Tech Institute Nguyen Tat Thanh University Ho Chi Minh City Viet Nam Institute of Natural Products Chemistry Vietnam Academy of Science and Technology Ha Noi City Viet Nam Center of Excellence for Biochemistry and Natural Products Nguyen Tat Thanh University Ho Chi Minh City Viet Nam

Essential oil of Ocimum gratissimum Linn. leaf is widely used in folk medicine. Extraction yeild, compositions and antioxidant activity of clove basil essential oils could be affected by several factors including drying temperature and storage conditions. The present work evaluated the influence of storage conditions and drying temperature different of Ocimum gratissimum leaves on essential oils from Central highlands, Vietnam. In this research, fresh leaves were preserved at 4°C for 10 days and dried and then stored at room temperature. Essential oil of Ocimum gratissimum L. was extracted by hydrodistillation and steam distillation methods. The composition of essential oil was determined by using GC-MS, antioxidation activities were conducted by the DPPH method. Drying the material at 450C only 1% Decrease extraction yield, the extraction yield of essential oil at 45°C is still high (2.5%);the color of the oil when the material is fresh in yellow, characteristic odor, drying at 45°C is pale yellow, mild characteristic odor;Antioxidation resistance change is negligible;Drying the material at 450C, the content of eugenol (77.389%) increased 3 fold compared with fresh material (24.84%), while the drying loss of some components small proportion in oil. © 2019 Elsevier Ltd. All rights reserved.

关键词： Essential oils

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Extraction of saponin from gleditsia peel and applications on natural dishwashing liquid detergent 9

Extraction of saponin from gleditsia peel and applications o...

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9th International Conference of Materials Processing and Characterization, ICMPC 2019

作者： Do, Dinh Nhat Dang, Tan Tai Le, Quang Tuan Lam, Tri Duc Bach, Long Giang Nguyen, Duy Chinh Toan, Tran Quoc Faculty of Chemical Engineering and Food Technology Nguyen Tat Thanh University Ho Chi Minh City Viet Nam NTT Hi-Tech Institute Nguyen Tat Thanh University Ho Chi Minh City Viet Nam Institute of Natural Products Chemistry Vietnam Academy of Science and Technology Ha Noi City Viet Nam Center of Excellence for Biochemistry and Natural Products Nguyen Tat Thanh University Ho Chi Minh City Viet Nam

Natural-derived products are becoming a new trend in the household products. In this research, crude saponin was extracted from Gleditsia peel by soxhlet extraction method. This compound was the main component that was used for producing natural dishwashing liquid detergent which is environmentally friendly and safe for the user's health. The highest crude saponin recovery yield is 31%, when the extraction process is performed for 2 days, at 85°C and the solvent is ethanol 40%. Saponin was used as emulsifier and surfactant, combine with other natural ingredients to produce natural dishwashing liquid detergent. That was formulated with ingredients of natural origin (9% crude saponin extracted from Gleditsia peel, 5% coco-glucosides, 1.5% carboxymethyl cellulose, 0.05% pomelo esential oil, pH regulator from banana peel ash and water). This product was evaluated through color, odor, pH, viscosity, washing ability and foaming properties. The results showed that this product has similar cleansing properties to commercial dishwashing liquids. © 2019 Published by Elsevier Ltd.

关键词： Liquids

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Liposomale Enzym-Nanoreaktoren auf Basis von Nanoconfinement für eine effiziente Anti-Tumor-Therapie

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Angewandte Chemie 2023年第44期135卷

作者： Ran Wang Yingjie Yu Dr. Meiyu Gai Dr. Ana Mateos Maroto Dr. Svenja Morsbach Xiang Xia Maomao He Prof. Jiangli Fan Prof. Xiaojun Peng Prof. Katharina Landfester Prof. Shuai Jiang Prof. Wen Sun State Key Laboratory of Fine Chemicals Frontiers Science Center for Smart Materials Oriented Chemical Engineering Dalian University of Technology 2 Linggong Road Hi-tech Zone Dalian 116024 China Diese Autoren haben zu gleichen Teilen zu der Arbeit beigetragen. Key Laboratory of Marine Drugs Chinese Ministry of Education School of Medicine and Pharmacy Ocean University of China Qingdao 266003 China Max Planck Institute for Polymer Research Ackermannweg 10 55128 Mainz Deutschland Ningbo Institute of Dalian University of Technology No. 26 Yucai Road Jiangbei District Ningbo 315016 China

Enzymatische Reaktionen können endogene Nährstoffe eines Tumors verbrauchen und zytotoxische Spezies erzeugen und sind daher vielversprechende Werkzeuge für die Behandlung bösartiger Tumore. Inspiriert von der Natur, in der Enzyme in Membranen kompartimentiert sind, um eine hohe Reaktionseffizienz zu erreichen und biologische Prozesse von der Umwelt zu trennen, entwickelten wir liposomale Nanoreaktoren, die enzymatische Kaskadenreaktionen im wässrigen Nanoconfinement des Liposoms durchführen können. Die Nanoreaktoren hemmten das Tumorwachstum in vivo effektiv, indem sie Tumornährstoffe (Glukose und Sauerstoff) verbrauchten und hochgradig zytotoxische Hydroxylradikale (⋅OH) produzierten. Die Ko-Kompartimentierung von Glukoseoxidase (GOx) und Meerrettichperoxidase (HRP) in Liposomen konnte die lokale Konzentration des Zwischenprodukts Wasserstoffperoxid (H 2 O 2 ) sowie den Säuregrad aufgrund der Bildung von Gluconsäure durch GOx erhöhen. Sowohl H 2 O 2 als auch der Säuregehalt beschleunigten die zweite Stufe der Reaktion durch HRP und verbesserten so die Gesamteffizienz der Kaskadenreaktion. Die biomimetische Kompartimentierung enzymatischer Tandemreaktionen in biokompatiblen Liposomen ist ein vielversprechender Weg für die Entwicklung katalytischer Nanomedikamente für die Antitumortherapie.

关键词： Anti-Cancer Therapy Biomimetic Systems Cascade Reactions Catalytic Nanomedicines Liposomes

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Dynamic response analysis and blade stiffness sensitivity study of large floating offshore wind turbine with coupling effect

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Renewable Energy 2025年

作者： Xiaohang Qian Zhiteng Gao Yibin He Leqi Song Jian Hu Lijun Zhang Tongguang Wang Ye Li Department of Ocean Science and Engineering Southern University of Science and Technology Shenzhen 518055 China Institute of Energy Science College of Engineering Shantou University Shantou 515063 China College of Metrology Measurement and Instrument China Jiliang University Hangzhou 310000 China Laboratory of Multi-function Towing Tank State Key Laboratory of Ocean Engineering School of Naval Architecture Ocean & Civil Engineering Shanghai Jiao Tong University Shanghai 200240 China Jiangsu Key Laboratory of Hi-Tech Research for Wind Turbine Design Nanjing University of Aeronautics and Astronautics Nanjing 210016 China School of Engineering The University of Edinburgh Edinburgh EH9 3JL United Kingdom Department of Civil and Mechanical Engineering Technical University of Denmark Nils Koppels Allé Kgs 2800 Kgs. Lyngby Denmark Department of Wind and Energy Systems Technical University of Denmark Nils Koppels Allé Kgs 2800 Kgs. Lyngby Denmark

The rise in offshore wind energy deployment has driven the design of larger blades, creating a trade-off between structural optimization and economic feasibility. To investigate the interaction between structural and sub-component responses in offshore floating wind turbine blades, a multi-body dynamics method, geometrically exact beam theory, and coupled blade element momentum theory were employed. A dynamic model was developed to assess the dynamic response of the 15 MW floating wind turbine under steady wind conditions. The geometrically exact beam theory accounts for the complete 6×6 stiffness matrix and incorporates sensitivity analysis factors to quantify the influence of all stiffness components on the response of each sub-component. The results indicate that, for the principal diagonal stiffness, torsional stiffness has a significant impact on the response, with a sensitivity factor of −100 concerning the blade tip’s twist angle fluctuation. For the coupling stiffness, the torsion-bending coupling stiffness induces considerable divergence in the response, with its sensitivity factor reaching −657.22 for twist angle fluctuations. The six-degree-of-freedom platform motion intensifies the coupling of the torsion-bending coupling stiffness with blade dynamics, leading to amplified response fluctuations and vibration divergence.

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Effects of extraction conditions on total phenolic content and total flavonoid content of roselle (hibiscus sabdariffa l.) extracts 8th

Effects of extraction conditions on total phenolic content a...

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8th International Conference on Advanced Materials and engineering Materials, ICAMEM 2019

作者： Duy, Nguyen Quoc Binh, Mai Le Thanh Thuan, Ma Van, Ngo Thi Thanh Lam, Tri Duc Tran, Thien hien Nhan, Phu Nguyen Thuong Faculty of Chemical Engineering and Food Technology Nguyen Tat Thanh University Ho Chi Minh City Viet Nam NTT Hi-Tech Institute Nguyen Tat Thanh University Ho Chi Minh City Viet Nam Center of Excellence for Biochemistry and Natural Products Nguyen Tat Thanh University Ho Chi Minh City Viet Nam

ISBN: (纸本)9783035714883

The objective of this study was to determine the optimal value of factors affecting the extraction of compounds such as, polyphenols, flavonoids of Roselle. The investigated factors included extraction temperatures (30, 40, 50, 60, 70 and 80°C), extraction time (30, 60, 90, 120 and 150 minutes) and solid to solvent ratio (1:5, 1:10, 1:20, 1:40 and 1:50 g/mL). The efficiency of extraction was evaluated based on total phenolic content (TPC) and total flavonoid content (TFC). The results showed that temperature range of 60–80°C was the appropriate temperature for TFC while extraction temperature over 60°C was suitable for achieving highest TPC. Considering the effect of extraction time, duration of 90–150 minutes facilitated the extraction of both phenolics and flavonoids. Moreover, the solid to solvent 1:20 was chosen for extraction process based on the balance of antioxidant contents and their yield. © 2019 Trans tech Publications Ltd, Switzerland.

关键词： Extraction

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Erratum: Designing Potential Inhibitors of SARS-CoV-2 Mpro Using Deep Learning and Steered Molecular Dynamic Simulations

Journal of Computational Biophysics and Chemistry

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Journal of Computational Biophysics and Chemistry 2023年第6期22卷 763-763页

作者： Nguyen Minh Tam Linh Hoang Tran Quan V. Vo Minh Quan Pham Huong Thi Thu Phung Laboratory of Theoretical and Computational Biophysics Advanced Institute of Materials Science Ton Duc Thang University Ho Chi Minh City Vietnam Faculty of Pharmacy Ton Duc Thang University Ho Chi Minh City Vietnam Present address: Faculty of Basic Sciences University of Phan Thiet Phan Thiet City Binh Thuan Vietnam. Faculty of Civil Engineering Ho Chi Minh University of Technology (HCMUT) Vietnam National University Ho Chi Minh City Vietnam Vietnam National University Ho Chi Minh City Ho Chi Minh City Vietnam Faculty of Chemical Technology-Environment The University of Danang — University of Technology and Education Danang Vietnam Institute of Natural Products Chemistry Vietnam Academy of Science and Technology Hanoi Vietnam Graduate University of Science and Technology Vietnam Academy of Science and Technology Hanoi Vietnam NTT Hi-Tech Institute Nguyen Tat Thanh University Ho Chi Minh City Vietnam

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Unveiling the SERS activity of silver triangular nanoplates in the enhanced detection of 4-mercaptobenzoic acid

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Optik 2021年 248卷 168155-168155页

作者： Anh, Mai Ngoc Tuan Nguyen, Dinh Tien Dung Ching, Yern Chee Thanh, Ngo Vo Ke Phong, Nguyen Thi Phuong Nguyen, Dai Hai Bui, Bao Truc Nguyen-Le, Minh-Tri Research Laboratories of Sai Gon Hi-Tech Park Lot I3 N2 Street Tan Phu Ward District 9 Ho Chi Minh City70000 Viet Nam Faculty of Chemistry University of Science Vietnam National University Ho Chi Minh City 227 Nguyen Van Cu Street District 5 Ho Chi Minh City70000 Viet Nam Institute of Fundamental and Applied Sciences Duy Tan University Ho Chi Minh City700000 Viet Nam Faculty of Natural Science Duy Tan University Danang City550000 Viet Nam Department of Chemical Engineering Faculty of Engineering University of Malaya Kuala Lumpur50603 Malaysia Graduate University of Science and Technology Vietnam Academy of Science and Technology Hanoi Viet Nam Institute of Applied Materials Science Vietnam Academy of Science and Technology 01 TL29 District 12 Ho Chi Minh City700000 Viet Nam Churchill College University of Cambridge Storey's way CambridgeUK United Kingdom

Silver triangular nanoplates (SNPs) have gained much attraction worldwide due to their unique optical properties. In our study, we investigated the growth of SNPs via a modified seed-mediated method with NaBH4 as a primary reductant, ascorbic acid (AA) as a secondary reductant and H2O2 as a seed corrosive agent. It was found that small sized spherical seeds with low surface plasmon resonance were obtained in the presence of H2O2. The seed size played a key role for SNPs formation. SNPs size was found to be proportional to the seed size. The experimental results also provided the missing piece of role of AA in the formation of SNPs. The effects of AA on the formation of SNPs in the presence of H2O2 and without H2O2 were investigated via SEM, TEM and UV–Vis measurements. For each case, increasing AA content up to [AA]:[Ag+] ratio of 1.0 would result in increasing the SNPs size and their uniformity. Above that ratio, smaller sized and less uniform SNPs were observed. Smaller sized SNPs fabricated by a seed-mediated method in the presence of H2O2 exhibit stronger SERS enhancement of 4-mercaptobezoic acid than those without H2O2. © 2021 Elsevier GmbH

关键词： Silver

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