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arXiv 2025年

作者： Wu, Ruiqi Su, Na Zhang, Chenran Ma, Tengfei Zhou, Tao Cui, Zhiting Tang, Nianfeng Mao, Tianyu Zhou, Yi Fan, Wen Wu, Tianxing Jing, Shenqi Fu, Huazhu School of Computer Science and Engineering Southeast University Nanjing China Department of Ophthalmology The First Affiliated Hospital of Nanjing Medical University Nanjing China School of Computer Science and Engineering Nanjing University of Science and Technology Nanjing China Institute of High-Performance Computing Agency for Science Technology and Research Singapore

Vision-language pretraining (VLP) has been investigated to generalize across diverse downstream tasks for fundus image analysis. Although recent methods showcase promising achievements, they significantly rely on large-scale private image-text data but pay less attention to the pretraining manner, which limits their further advancements. In this work, we introduce MM-Retinal V2, a high-quality image-text paired dataset comprising CFP, FFA, and OCT image modalities. Then, we propose a novel fundus vision-language pretraining model, namely KeepFIT V2, which is pretrained by integrating knowledge from the elite data spark into categorical public datasets. Specifically, a preliminary textual pretraining is adopted to equip the text encoder with primarily ophthalmic textual knowledge. Moreover, a hybrid image-text knowledge injection module is designed for knowledge transfer, which is essentially based on a combination of global semantic concepts from contrastive learning and local appearance details from generative learning. Extensive experiments across zero-shot, few-shot, and linear probing settings highlight the generalization and transferability of KeepFIT V2, delivering performance competitive to state-of-the-art fundus VLP models trained on large-scale private image-text datasets. Our dataset and model are publicly available via https://***/lxirich/MM-Retinal. Copyright © 2025, The Authors. All rights reserved.

关键词： Semantics

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Fundus Image Quality Assessment and Enhancement: a Systematic Review

arXiv

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arXiv 2025年

作者： Li, Heng Li, Haojin Ou, Mingyang Yu, Xiangyang Zhang, Xiaoqing Niu, Ke Fu, Huazhu Liu, Jiang Research Institute of Trustworthy Autonomous Systems SUSTech Shenzhen China Department of Computer Science and Engineering SUSTech Shenzhen China Center for High Performance Computing and Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China Computer School Beijing Information Science and Technology University Beijing China Singapore

As an affordable and convenient eye scan, fundus photography holds the potential for preventing vision impairment, especially in resource-limited regions. However, fundus image degradation is common under intricate imaging environments, impacting following diagnosis and treatment. Consequently, image quality assessment (IQA) and enhancement (IQE) are essential for ensuring the clinical value and reliability of fundus images. While existing reviews offer some overview of this field, a comprehensive analysis of the interplay between IQA and IQE, along with their clinical deployment challenges, is lacking. This paper addresses this gap by providing a thorough review of fundus IQA and IQE algorithms, research advancements, and practical applications. We outline the fundamentals of the fundus photography imaging system and the associated interferences, and then systematically summarize the paradigms in fundus IQA and IQE. Furthermore, we discuss the practical challenges and solutions in deploying IQA and IQE, as well as offer insights into potential future research directions. Copyright © 2025, The Authors. All rights reserved.

关键词： Photography

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From Failure to Insight: Analyzing Disk Breakdowns in Large-Scale HPC Environments 24

From Failure to Insight: Analyzing Disk Breakdowns in Large-...

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Proceedings of the SC '24 Workshops of the International Conference on high performance computing, Network, Storage, and Analysis

作者： Anjus George Meng Wang Jesse Hanley Garrett Wilson Ransom John Bent Christopher Zimmer National Center for Computational Sciences Oak Ridge National Laboratory Oak Ridge TN USA Department of Computer Science University of Chicago Chicago IL USA HPC Infrastructure Los Alamos National Laboratory Los Alamos NM USA High Performance Computing Los Alamos National Laboratory Los Alamos NM USA

ISBN: (纸本)9798350355543

Disk failure data provides valuable insights for preventing failures, enhancing storage robustness, guiding system design and deployment, and ensuring reliable operations at data centers. This paper introduces two disk failure datasets collected from large-scale HPC production environments over the past five years, comprising over 5,000 failure records from more than 40,000 disks. We analyzed these datasets across multiple dimensions, including temporal, spatial, and relational trends, and performed a comprehensive reliability assessment. Our analysis yielded numerous observations and insights that influence various operational aspects of HPC storage systems. We believe this study offers a holistic understanding of disk failure trends likely to interest the HPC storage community.

关键词： Cause effect analysis

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Enabling All-to-Circular Polarization Up-Conversion by Nonlinear Chiral Metasurfaces with Rotational Symmetry

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Physical Review Letters 2025年第2期134卷 023804-023804页

作者： Dmitrii Gromyko Jun Siang Loh Jiangang Feng Cheng-Wei Qiu Lin Wu Science Mathematics and Technology (SMT) Singapore University of Technology and Design (SUTD) 8 Somapah Road 487372 Singapore Singapore Department of Electrical and Computer Engineering National University of Singapore 4 Engineering Drive 3 117583 Singapore Singapore Institute of High Performance Computing ASTAR (Agency for Science Technology and Research) 1 Fusionopolis Way No. 16-16 Connexis 138632 Singapore Singapore

We introduce a stacking strategy to design nonlinear chiral metasurfaces with high rotational symmetry, enabling degenerate quasi-bound-in-the-continuum resonances of absolute chirality. This symmetry allows for converting a circularly polarized pump into a circularly polarized nonlinear signal. Consequently, our rotation-symmetric bilayered metasurface design, tailored to respond solely to one specific circular polarization, can up-convert a linear or arbitrary polarized pump into circularly polarized nonlinear signals. The intensity ratios of these signals scale as the fourth (second) power of the chiral resonance amplitude for the second (third) harmonic.

关键词： Circular polarization

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Vision-Amplified Semantic Entropy for Hallucination Detection in Medical Visual Question Answering

arXiv

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arXiv 2025年

作者： Liao, Zehui Hu, Shishuai Zou, Ke Fu, Huazhu Zhen, Liangli Xia, Yong National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology School of Computer Science and Engineering Northwestern Polytechnical University Xi’an710072 China Institute of High Performance Computing Agency for Science Technology and Research Singapore138632 Singapore National University of Singapore Singapore119077 Singapore

Multimodal large language models (MLLMs) have demonstrated significant potential in medical Visual Question Answering (VQA). Yet, they remain prone to hallucinations—incorrect responses that contradict input images, posing substantial risks in clinical decision-making. Detecting these hallucinations is essential for establishing trust in MLLMs among clinicians and patients, thereby enabling their real-world adoption. Current hallucination detection methods, especially semantic entropy (SE), have demonstrated promising hallucination detection capacity for LLMs. However, adapting SE to medical MLLMs by incorporating visual perturbations presents a dilemma. Weak perturbations preserve image content and ensure clinical validity, but may be overlooked by medical MLLMs, which tend to over rely on language priors. In contrast, strong perturbations can distort essential diagnostic features, compromising clinical interpretation. To address this issue, we propose Vision Amplified Semantic Entropy (VASE), which incorporates weak image transformations and amplifies the impact of visual input, to improve hallucination detection in medical VQA. We first estimate the semantic predictive distribution under weak visual transformations to preserve clinical validity, and then amplify visual influence by contrasting this distribution with that derived from a distorted image. The entropy of the resulting distribution is estimated as VASE. Experiments on two medical open-ended VQA datasets demonstrate that VASE consistently outperforms existing hallucination detection methods. Copyright © 2025, The Authors. All rights reserved.

关键词： Semantics

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INDUCTIVE LIMITS OF COMPACT QUANTUM METRIC SPACES

arXiv

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arXiv 2025年

作者： Long, Botao Sadeghi, Ghadir School of Mathematics MIIT Key Laboratory of Mathematical Modelling and High Performance Computing of Air Vehicles Nanjing University of Aeronautics and Astronautics Jiangsu Nanjing211106 China Department of Mathematics and Computer Sciences Hakim Sabzevari University P. O. Box 397 Sabzevar Iran

A compact quantum metric space is a unital C∗-algebra equipped with a Lip-norm. Let {(An, Ln)} be a sequence of compact quantum metric spaces, and let φn: An → An+1 be a unital ∗-homomorphism preserving Lipschitz elements for n ≥ 1. We show that there exists a compact quantum metric space structure on the inductive limit (Formula Presented) by means of the inverse limit of the state spaces {S(An)}. We also give some sufficient conditions that two inductive limits of compact quantum metric spaces are Lipschitz *** Codes 46L85(Primary) 46L87, 58B34(Secondary) Copyright © 2025, The Authors. All rights reserved.

关键词： Inverse problems

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AIF-SFDA: Autonomous Information Filter-driven Source-Free Domain Adaptation for Medical Image Segmentation

arXiv

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arXiv 2025年

作者： Li, Haojin Li, Heng Chen, Jianyu Zhong, Rihan Niu, Ke Fu, Huazhu Liu, Jiang Research Institute of Trustworthy Adaptive Systems Southern University of Science and Technology China Department of Computer Science and Engineering Southern University of Science and Technology China Beijing Information Science & Technology University China Institute of High Performance Computing Agency for Science Technology and Research Singapore

Decoupling domain-variant information (DVI) from domain-invariant information (DII) serves as a prominent strategy for mitigating domain shifts in the practical implementation of deep learning algorithms. However, in medical settings, concerns surrounding data collection and privacy often restrict access to both training and test data, hindering the empirical decoupling of information by existing methods. To tackle this issue, we propose an Autonomous Information Filter-driven Source-free Domain Adaptation (AIF-SFDA) algorithm, which leverages a frequency-based learnable information filter to autonomously decouple DVI and DII. Information Bottleneck (IB) and Self-supervision (SS) are incorporated to optimize the learnable frequency filter. The IB governs the information flow within the filter to diminish redundant DVI, while SS preserves DII in alignment with the specific task and image modality. Thus, the autonomous information filter can overcome domain shifts relying solely on target data. A series of experiments covering various medical image modalities and segmentation tasks were conducted to demonstrate the benefits of AIF-SFDA through comparisons with leading algorithms and ablation studies. The code is available at https://***/JingHuaMan/AIF-SFDA. Copyright © 2025, The Authors. All rights reserved.

关键词： Image segmentation

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Deep Neural Cellular Potts Models

arXiv

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arXiv 2025年

作者： Minartz, Koen d’Hondt, Tim Hillmann, Leon Starruß, Jörn Brusch, Lutz Menkovski, Vlado Department of Mathematics and Computer Science Eindhoven University of Technology Eindhoven Netherlands Department of Applied Physics and Science Education Eindhoven University of Technology Eindhoven Netherlands Department of Biomedical Engineering Eindhoven University of Technology Eindhoven Netherlands Center for Information Services and High Performance Computing TUD Dresden University of Technology Dresden Germany

The cellular Potts model (CPM) is a powerful computational method for simulating collective spatiotemporal dynamics of biological cells. To drive the dynamics, CPMs rely on physics-inspired Hamiltonians. However, as first principles remain elusive in biology, these Hamiltonians only approximate the full complexity of real multicellular systems. To address this limitation, we propose NeuralCPM, a more expressive cellular Potts model that can be trained directly on observational data. At the core of NeuralCPM lies the Neural Hamiltonian, a neural network architecture that respects universal symmetries in collective cellular dynamics. Moreover, this approach enables seamless integration of domain knowledge by combining known biological mechanisms and the expressive Neural Hamiltonian into a hybrid model. Our evaluation with synthetic and real-world multicellular systems demonstrates that NeuralCPM is able to model cellular dynamics that cannot be accounted for by traditional analytical Hamiltonians. Copyright © 2025, The Authors. All rights reserved.

关键词： Potts model

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A Digital 3D TCAM Accelerator for the Inference Phase of Random Forest 23

A Digital 3D TCAM Accelerator for the Inference Phase of Ran...

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Proceedings of the 60th Annual ACM/IEEE Design Automation Conference

作者： Chieh-Lin Tsai Chun-Feng Wu Yuan-Hao Chang Han-Wen Hu Yung-Chun Lee Hsiang-Pang Li Tei-Wei Kuo Department of Computer Science and Information Engineering National Taiwan University Department of Computer Science National Yang Ming Chiao Tung University Institute of Information Science Academia Sinica Taiwan Macronix International Co. Ltd and Department of Electrical Engineering National Tsing Hua University Macronix International Co. Ltd Department of Computer Science and Information Engineering National Taiwan University and Mohamed Bin Zayed University of Artificial Intelligence and NTU High Performance and Scientific Computing Center National Taiwan University

ISBN: (纸本)9798350323481

Random forest is a popular ensemble machine-learning algorithm for classification and regression tasks. However, the irregular tree shapes and non-deterministic memory access patterns make it hard for the current von Neumann architecture to handle random forest efficiently. This paper proposes a digital 3D TCAM-based accelerator for the random forest, adopting the idea of processing-in-memory (PIM) to reduce data movement. By utilizing this accelerator, we propose a TCAM-based approach to provide real-time inference with low energy consumption, making it suitable for edge or embedded environments. In the experiments, the proposed approach achieves an average of 3.13 times higher throughput with 22 times more energy saving than the GPU approach.

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FundusGAN: A Hierarchical Feature-Aware Generative Framework for high-Fidelity Fundus Image Generation

arXiv

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arXiv 2025年

作者： Hou, Qingshan Wang, Meng Cao, Peng Ke, Zou Liu, Xiaoli Fu, Huazhu Zaiane, Osmar R. Computer Science and Engineering Northeastern University Shenyang China Key Laboratory of Intelligent Computing in Medical Image of Ministry of Education Northeastern University Shenyang China Alberta Machine Intelligence Institute University of Alberta Edmonton Canada Ophthalmology Yong Loo Lin School of Medicine National University of Singapore Singapore Institute of High Performance Computing Agency for Science Technology and Research Singapore

Recent advancements in ophthalmology foundation models such as RetFound have demonstrated remarkable diagnostic capabilities but require massive datasets for effective pre-training, creating significant barriers for development and deployment. To address this critical challenge, we propose FundusGAN, a novel hierarchical feature-aware generative framework specifically designed for high-fidelity fundus image synthesis. Our approach leverages a Feature Pyramid Network within its encoder to comprehensively extract multi-scale information, capturing both large anatomical structures and subtle pathological features. The framework incorporates a modified StyleGAN-based generator with dilated convolutions and strategic upsampling adjustments to preserve critical retinal structures while enhancing pathological detail representation. Comprehensive evaluations on the DDR, DRIVE, and IDRiD datasets demonstrate that FundusGAN consistently outperforms state-of-the-art methods across multiple metrics (SSIM: 0.8863, FID: 54.2, KID: 0.0436 on DDR). Furthermore, disease classification experiments reveal that augmenting training data with FundusGAN-generated images significantly improves diagnostic accuracy across multiple CNN architectures (up to 6.49% improvement with ResNet50). These results establish FundusGAN as a valuable foundation model component that effectively addresses data scarcity challenges in ophthalmological AI research, enabling more robust and generalizable diagnostic systems while reducing dependency on large-scale clinical data collection. Copyright © 2025, The Authors. All rights reserved.

关键词： Ophthalmology

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