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2022 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2022

作者： Liu, Yajun Ding, Yulian Li, Aimin Fei, Rong Guo, Xie Wu, Fangxiang Xi'an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology Xi'an China University of Saskatchewan Division of Biomedical Engineering Saskatoon Canada Xi'an University of Technology Shaanxi Key Laboratory of Complex System Control and Intelligent Information Processing Xi'an China University of Saskatchewan Division of Biomedical Engineering Department of Computer Science Department of Mechanical Engineering Saskatoon Canada

ISBN: (纸本)9781665468190

PIWI-interacting RNAs (piRNAs) are a type of small non-coding RNAs which bind with the PIWI proteins to exert biological effects in various regulatory mechanisms. A growing amount of evidence reveals that exosomal piRNAs are potential biomarkers for diagnosis and treatment of complex diseases. Effective methods for the prediction of exosomal piRNAs are the foundation of piRNA functional research. In this study, we propose an end-to-end deep network for identifying exosomal piRNAs based on features learned from natural language processing (NLP) models for sequence embedding with attention mechanism. First, a benchmark dataset is constructed by processing piRNA subcellular localization annotated data and sequence data. Moreover, bagging positive unlabeled learning is applied to get the reliable negative set. Finally, we treat a piRNA sequence as a sentence and its k-mer subsequence as a token. Sequence embedding models with self-attention mechanism is designed to extract features from exosome piRNA sequences, which are used for the prediction task. Compared with three competing methods, our model achieves the best performance and reveals the key factors of exosomal piRNA sequences by the attention mechanism. Our model characterizes exosomal piRNAs and could be beneficial for researchers to investigate exosomal piRNAs' functions. © 2022 IEEE.

关键词： Embeddings

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Hybrid Variational Autoencoder for Collaborative Filtering 25

Hybrid Variational Autoencoder for Collaborative Filtering

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25th IEEE International Conference on computer Supported Cooperative Work in Design, CSCWD 2022

作者： Liu, Jinxin Xiao, Yingyuan Zhu, Ke Zheng, Wenguang Hsu, Ching-Hsien Tianjin University of Technology Engineering Research Center of Learning-Based Intelligent System Ministry of Education Tianjin China Tianjin University of Technology Tianjin Key Laboratory of Intelligence Computing and Novel Software Technology Tianjin China Asia University Department of Computer Science and Information Engineering Taichung Taiwan

ISBN: (纸本)9781665405270

In recent years, Variational AutoEncoder (VAE) based methods have made many important achievements in the field of collaborative filtering recommendation system. VAE is a kind of Bayesian model which combines latent variable model with variational inference, but its optimization is often troubled by posterior collapse. By comparing the optimization process of VAE and ordinary autoencoder, we observe that the mismatch between poorly optimized encoder and decoder with too strong characterization capabilities makes it difficult to learn the mapping from the data manifold to the parameterized graph. Since the learning of a posteriori network corresponds to the encoder, we think that the problem of a posteriori collapse can be alleviated by balancing the encoder and decoder better. Therefore, we proposed Hy-VAE, which combines conventional VAE with deterministic autoencoder, and has the advantages of both VAE and deterministic autoencoder. Experiments on three real-world recommendation data sets show that our method alleviates the posterior crash problem in VAE and improves the recommendation performance. © 2022 IEEE.

关键词： Collaborative filtering

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A deep learning system for predicting time to progression of diabetic retinopathy

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NATURE MEDICINE 2024年第2期30卷 358-359页

作者： [Anonymous] Shanghai Belt and Road International Joint Laboratory for Intelligent Prevention and Treatment of Metabolic Disorders Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes Shanghai China MOE Key Laboratory of AI School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai China Department of Ophthalmology Huadong Sanatorium Wuxi China Department of Ophthalmology Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong China Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong China Department of Chemical and Biological Engineering The Hong Kong University of Science and Technology Hong Kong China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Department of Ophthalmology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing China Medical Records and Statistics Office Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Geriatrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Tech

We developed and validated a deep learning system (termed DeepDR Plus) in a diverse, multiethnic, multi-country dataset to predict personalized risk and time to progression of diabetic retinopathy. We show that DeepDR Plus can be integrated into the clinical workflow to promote individualized intervention strategies for the management of diabetic retinopathy.

关键词： Diabetes complications Machine learning Predictive markers

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Contrastive Learning of Person-independent Representations for Facial Action Unit Detection

arXiv

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arXiv 2024年

作者： Li, Yong Shan, Shiguang The Key Laboratory of Intelligent Perception and Systems for High-Dimensional Information Ministry of Education School of Computer Science and Engineering Nanjing University of Science and Technology Nanjing210094 China The Key Laboratory of Intelligent Information Processing Chinese Academy of Sciences Institute of Computing Technology CAS Beijing100190 China The University of Chinese Academy of Sciences Beijing100049 China Peng Cheng Laboratory Shenzhen518055 China

Facial action unit (AU) detection, aiming to classify AU present in the facial image, has long suffered from insufficient AU annotations. In this paper, we aim to mitigate this data scarcity issue by learning AU representations from a large number of unlabelled facial videos in a contrastive learning paradigm. We formulate the self-supervised AU representation learning signals in two-fold: (1) AU representation should be frame-wisely discriminative within a short video clip;(2) Facial frames sampled from different identities but show analogous facial AUs should have consistent AU representations. As to achieve these goals, we propose to contrastively learn the AU representation within a video clip and devise a cross-identity reconstruction mechanism to learn the person-independent representations. Specially, we adopt a margin-based temporal contrastive learning paradigm to perceive the temporal AU coherence and evolution characteristics within a clip that consists of consecutive input facial frames. Moreover, the cross-identity reconstruction mechanism facilitates pushing the faces from different identities but show analogous AUs close in the latent embedding space. Experimental results on three public AU datasets demonstrate that the learned AU representation is discriminative for AU detection. Our method outperforms other contrastive learning methods and significantly closes the performance gap between the self-supervised and supervised AU detection approaches. © 2024, CC BY.

关键词： Learning systems

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COph100: A comprehensive fundus image registration dataset from infants constituting the "RIDIRP" database

arXiv

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arXiv 2025年

作者： Hu, Yan Gong, Mingdao Qiu, Zhongxi Liu, Jiabao Shen, Hongli Yuan, Mingzhen Zhang, Xiaoqing Li, Heng Lu, Hai Liu, Jiang Research Institute of Trustworthy Autonomous Systems Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen China Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology and Visual Sciences Key Laboratory Beijing China Center for High Performance Computing and Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China

Retinal image registration is vital for diagnostic therapeutic applications within the field of ophthalmology. Existing public datasets, focusing on adult retinal pathologies with high-quality images, have limited number of image pairs and neglect clinical challenges. To address this gap, we introduce COph100, a novel and challenging dataset known as the Comprehensive Ophthalmology Retinal Image Registration dataset for infants with a wide range of image quality issues constituting the public "RIDIRP" database1. COph100 consists of 100 eyes, each with 2 to 9 examination sessions, amounting to a total of 491 image pairs carefully selected from the publicly available dataset. We manually labeled the corresponding ground truth image points and provided automatic vessel segmentation masks for each image. We have assessed COph100 in terms of image quality and registration outcomes using state-of-the-art algorithms. This resource enables a robust comparison of retinal registration methodologies and aids in the analysis of disease progression in infants, thereby deepening our understanding of pediatric ophthalmic conditions. Copyright © 2025, The Authors. All rights reserved.

关键词： Image registration

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Dual-scale Enhanced and Cross-generative Consistency Learning for Semi-supervised Medical Image Segmentation

arXiv

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arXiv 2023年

作者： Gu, Yunqi Zhou, Tao Zhang, Yizhe Zhou, Yi He, Kelei Gong, Chen Fu, Huazhu PCA Laboratory The School of Computer Science and Engineering Nanjing University of Science and Technology Nanjing210094 China The School of Computer Science and Engineering Southeast University Nanjing211189 China The Medical School Nanjing University Nanjing210023 China The National Institute of Healthcare Data Science Nanjing University Nanjing210023 China The Institute of High Performance Computing A*STAR Singapore

Medical image segmentation plays a crucial role in computer-aided diagnosis. However, existing methods heavily rely on fully supervised training, which requires a large amount of labeled data with time-consuming pixel-wise annotations. Moreover, accurately segmenting lesions poses challenges due to variations in shape, size, and location. To address these issues, we propose a novel Dual-scale Enhanced and Cross-generative consistency learning framework for semi-supervised medical image Segmentation (DEC-Seg). First, we propose a Cross-level Feature Aggregation (CFA) module that integrates cross-level adjacent layers to enhance the feature representation ability across different resolutions. To address scale variation, we present a scale-enhanced consistency constraint, which ensures consistency in the segmentation maps generated from the same input image at different scales. This constraint helps handle variations in lesion sizes and improves the robustness of the model. Furthermore, we propose a cross-generative consistency scheme, in which the original and perturbed images can be reconstructed using cross-segmentation maps. This consistency constraint allows us to mine effective feature representations and boost the segmentation performance. To further exploit the scale information, we propose a Dual-scale Complementary Fusion (DCF) module that integrates features from two scale-specific decoders operating at different scales to help produce more accurate segmentation maps. Extensive experimental results on multiple medical segmentation tasks (polyp, skin lesion, and brain glioma) demonstrate the effectiveness of our DECSeg against other state-of-the-art semi-supervised segmentation approaches. The implementation code will be released at https://***/taozh2017/DECSeg. Copyright © 2023, The Authors. All rights reserved.

关键词： Self-supervised learning

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Integrating Generative Artificial Intelligence Into Future Internet of Vehicles [From the Guest Editors]

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IEEE Vehicular Technology Magazine 2025年第2期20卷 40-42页

作者： Gang Sun Hongyang Du Abbas Jamalipour Gabriel-Miro Muntean Lin Cai Jiawen Kang Dusit Niyato University of Electronic Science and Technology of China Chengdu China Department of Electrical and Electronic Engineering The University of Hong Kong Hong Kong China University of Sydney Sydney NSW Australia Performance Engineering Laboratory Dublin City University Dublin Ireland Department of Electrical and Computer Engineering University of Victoria Victoria BC Canada Guangdong University of Technology Guangzhou China College of Computing and Data Science Nanyang Technological University Singapore Singapore

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computing Power in the Sky: Digital Twin-assisted Collaborative computing with Multi-UAV Networks

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IEEE Transactions on Vehicular Technology 2025年

作者： Wang, Chao Han, Yu Zhang, Long Jia, Ziye Zhang, Hongliang Hong, Choong Seon Han, Zhu Hebei University of Engineering School of Information and Electrical Engineering Handan056038 China Qilu University of Technology Shandong Academy of Sciences Key Laboratory of Computing Power Network and Information Security Ministry of Education Jinan250014 China Nanjing University of Aeronautics and Astronautics College of Electronic and Information Engineering Nanjing211106 China Southeast University National Mobile Communications Research Laboratory Jiangsu Nanjing211111 China Peking University State Key Laboratory of Advanced Optical Communication Systems and Networks School of Electronics Beijing100871 China Kyung Hee University Department of Computer Science and Engineering Gyeonggi-do Yongin-si17104 Korea Republic of University of Houston Department of Electrical and Computer Engineering HoustonTX77004 United States Kyung Hee University Department of Computer Science and Engineering Seoul446-701 Korea Republic of

The collaboration of computing powers (CPs) among unmanned aerial vehicles (UAVs)-mounted edge servers is essential to handle data-intensive tasks of user equipments (UEs). This paper presents a multi-UAV computing power network (CPN) that orchestrates the CP resources of edge servers to cooperatively process tasks through collaborative computing. Due to the frequent interactions among edge servers and the increased complexities for large-scale task executions, we propose a digital twin (DT)-driven multi-UAV CPN framework, where the aerial DT network is created as a digital replica of the multi-UAV network to assist collaborative computing. A joint optimization problem of the service association, offloading power control, task partitions, CP allocation, and UAV trajectory design is formulated to minimize the long-term average delay of UEs. We use the Lyapunov technique to tackle the long-term energy constraint, forming a tractable optimization problem, which is modeled as a Markov decision process to balance the UAV's deficit queue stability and the UE's task completion delay. A hybrid soft actor-critic based deep reinforcement learning algorithm is developed to optimize the joint design by sampling the hybrid action from the Gumbel and Gaussian distributions. Simulation results verify that the multi-UAV CPN contributes to significant performance gains when supported by DTs. © 2025 IEEE.

关键词： Markov processes

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dugMatting: Decomposed-Uncertainty-Guided Matting

arXiv

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arXiv 2023年

作者： Wu, Jiawei Zhang, Changqing Li, Zuoyong Fu, Huazhu Peng, Xi Zhou, Joey Tianyi College of Mechanical and Electrical Engineering Fujian Agriculture and Forestry University Fuzhou China College of Intelligence and Computing Tianjin University Tianjin China Fujian Provincial Key Laboratory of Information Processing and Intelligent Control Minjiang University Fuzhou China Institute of High Performance Computing Agency for Science Technology and Research Singapore College of Computer Science Sichuan University Chengdu China Singapore

Cutting out an object and estimating its opacity mask, known as image matting, is a key task in image and video editing. Due to the highly ill-posed issue, additional inputs, typically user-defined trimaps or scribbles, are usually needed to reduce the uncertainty. Although effective, it is either time consuming or only suitable for experienced users who know where to place the strokes. In this work, we propose a decomposed-uncertainty-guided matting (dugMatting) algorithm, which explores the explicitly decomposed uncertainties to efficiently and effectively improve the results. Basing on the characteristic of these uncertainties, the epistemic uncertainty is reduced in the process of guiding interaction (which introduces prior knowledge), while the aleatoric uncertainty is reduced in modeling data distribution (which introduces statistics for both data and possible noise). The proposed matting framework relieves the requirement for users to determine the interaction areas by using simple and efficient labeling. Extensively quantitative and qualitative results validate that the proposed method significantly improves the original matting algorithms in terms of both efficiency and efficacy. Copyright © 2023, The Authors. All rights reserved.

关键词： Uncertainty analysis

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Unprecedented Smart Algorithm for Uninterrupted SDN Services During DDoS Attack

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computers, Materials & Continua 2022年第1期70卷 875-894页

作者： Muhammad Reazul Haque Saw Chin Tan Zulfadzli Yusoff Kashif Nisar Rizaludin Kaspin Iram Haider Sana Nisar J.P.C.Rodrigues Bhawani Shankar Chowdhry Muhammad AslamUqaili Satya Prasad Majumder Danda B.Rawat Richard Etengu Rajkumar Buyya Faculty of Computing&Informatics Multimedia UniversityPersiaranMultimediaCyberjaya63100SelangorMalaysia Faculty of Engineering Multimedia UniversityPersiaran MultimediaCyberjaya63100SelangorMalaysia Faculty of Computing and Informatics University Malaysia SabahJalan UMSKota Kinabalu Sabah88400Malaysia Telekom Malaysia Research&Development TM Innovation Centre63000CyberjayaSelangorMalaysia Federal University of Piauí(UFPI) TeresinaPIBrazil Instituto de Telecomunica珲es 6201-001Covilh?Portugal National Center of Robotics and Automation-Condition Monitoring Systems Lab MUETJamshoroPakistan Department of Electrical and Electronic Engineering BUETDhaka1205Bangladesh Department of Electrical Engineering and Computer Science Data Science and Cybersecurity CenterHoward UniversityWashingtonDCUSA Cloud Computing and Distributed Systems(CLOUDS)Laboratory School of Computing and Information SystemsThe University of MelbourneMelbourneVIC 3053Australia

In the design and planning of next-generation Internet of Things(IoT),telecommunication,and satellite communication systems,controller placement is crucial in software-defined networking(SDN).The programmability of the SDN controller is sophisticated for the centralized control system of the entire ***,it creates a significant loophole for the manifestation of a distributed denial of service(DDoS)attack ***,recently a Distributed Reflected Denial of Service(DRDoS)attack,an unusual DDoS attack,has been ***,minimal deliberation has given to this forthcoming single point of SDN infrastructure failure ***,recently the high frequencies of DDoS attacks have increased *** this paper,a smart algorithm for planning SDN smart backup controllers under DDoS attack scenarios has *** proposed smart algorithm can recommend single or multiple smart backup controllers in the event of DDoS *** obtained simulated results demonstrate that the validation of the proposed algorithm and the performance analysis achieved 99.99%accuracy in placing the smart backup controller under DDoS attacks within 0.125 to 46508.7 s in SDN.

关键词： SDN smart algorithm RTZLK-DAASCP DDoS attack DRDoS

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