Neuronal morphology is an essential element for brain activity and function. We take advantage of current availability of brain-wide neuron digital reconstructions of the Pyramidal cells from a mouse brain, and analyz...
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We study a Wong-Zakai approximation for the random slow manifold of a slow-fast stochastic dynamical system. We first deduce the existence of the random slow manifold about an approximation system driven by an integra...
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We study stochastic bifurcation for a system under multiplicative stable Lévy noise (an important class of non-Gaussian noise), by examining the qualitative changes of equilibrium states in its most probable phas...
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The phenomena of diffusion in multicomponent (more than two components) mixtures are very universal in both science and engineering, and from mathematical point of view, they are usually described by the Maxwell-Stefa...
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We consider the relation for the stochastic equilibrium states between the reduced system on a random slow manifold and the original system. This provides a theoretical basis for the reduction about sophisticated deta...
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In this article, we are concerned with the following eigenvalue problem of a linear second order elliptic operator: − D∆φ − 2α∇m(x) · ∇φ + V (x)φ = λφ in Ω, complemented by a general boundary condition inc...
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In this paper, a lattice Boltzmann (LB) model with double distribution functions is proposed for two-phase flow in porous media where one distribution function is used for pressure governed by the Poisson equation, an...
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We study the most probable transition pathways and maximal likely trajectories in a genetic regulation model of the transcription factor activator’s concentration evolution, with Gaussian noise and non-Gaussian stabl...
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We study the most probable transition pathways and maximal likely trajectories in a genetic regulation model of the transcription factor activator’s concentration evolution, with Gaussian noise and non-Gaussian stable Lévy noise in the synthesis reaction rate taking into account, respectively. We compute the most probable transition pathways by the Onsager-Machlup least action principle, and calculate the maximal likely trajectories by spatially maximizing the probability density of the system path, i.e., the solution of the associated nonlocal Fokker-Planck equation. We have observed the rare most probable transition pathways in the case of Gaussian noise, for certain noise intensity, evolution time scale and system parameters. We have especially studied the maximal likely trajectories starting at the low concentration metastable state, and examined whether they evolve to or near the high concentration metastable state (i.e., the likely transcription regime) for certain parameters, in order to gain insights into the transcription processes and the tipping time for the transcription likely to occur. This enables us: (i) to visualize the progress of concentration evolution (i.e., observe whether the system enters the transcription regime within a given time period);(ii) to predict or avoid certain transcriptions via selecting specific noise parameters in particular regions in the parameter space. Moreover, we have found some peculiar or counter-intuitive phenomena in this gene model system, including: (a) A smaller noise intensity may trigger the transcription process, while a larger noise intensity can not, under the same asymmetric Lévy noise. This phenomenon does not occur in the case of symmetric Lévy noise;(b) The symmetric Lévy motion always induces transition to high concentration, but certain asymmetric Lévy motions do not trigger the switch to transcription. These findings provide insights for further experimental research, in order to achieve or to avoid sp
We establish quantitative results for the statistical behaviour of infinite systems. We consider two kinds of infinite system: i) a conservative dynamical system (f, X, µ) preserving a σ-finite measure µ su...
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In this work, we propose a fully discrete energy stable scheme for the phase-field moving contact line model with variable densities and viscosities. The mathematical model consists of a Cahn-Hilliard equation, a Navi...
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