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The burden and trend of diseases and their risk factors in Australia, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019

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LANCET PUBLIC HEALTH 2023年第8期8卷 E585-E599页

作者： Islam, Sheikh Mohammed Shariful Uddin, Riaz Maddison, Ralph Ball, Kylie Livingstone, Katherine M. Khan, Asaduzzaman Salmon, Jo Ackerman, Ilana N. Adair, Tim Adegboye, Oyelola A. Ademi, Zanfina Adhikary, Ripon Kumar Ahinkorah, Bright Opoku Alam, Khurshid Alene, Kefyalew Addis Alif, Sheikh Mohammad Amare, Azmeraw T. Ameyaw, Edward Kwabena Aminde, Leopold N. Anderlini, Deanna Angell, Blake Ansar, Adnan Antony, Benny Anyasodor, Anayochukwu Edward Arnet, Victoria Kiriaki Astell-Burt, Thomas Atorkey, Prince Awoke, Mamaru Ayenew Quintanilla, Beatriz Paulina Ayala Ayano, Getinet Bagheri, Nasser Barnett, Anthony Baune, Bernhard T. Bhandari, Dinesh Bhaskar, Sonu Biswas, Raaj Kishore Borschmann, Rohan Boufous, Soufiane Briggs, Andrew M. Buchbinder, Rachelle Bulamu, Norma B. Burns, Richard A. Carvalho, Andre F. Cerin, Ester Cherbuin, Nicolas Chowdhury, Enayet Karim Ciobanu, Liliana G. Clark, Scott Richard Cross, Marita Dadi, Abel Fekadu de Courten, Barbora De Leo, Diego de Luca, Katie Doyle, Kerrie E. Edvardsson, David Edvardsson, Kristina Efendi, Ferry Endalamaw, Aklilu Fauk, Nelsensius Klau Feng, Xiaoqi Fitzgibbon, Bernadette Mary Flavel, Joanne Gebreyohannes, Eyob Alemayehu Alemayehu Gesesew, Hailay Abrha Gill, Tiffany K. Godinho, Myron Anthony Gupta, Bhawna Gupta, Vivek Kumar Hambisa, Mitiku Teshome Hamiduzzaman, Mohammad Hankey, Graeme J. Hassanian-Moghaddam, Hossein Hay, Simon I. Hebert, Jeffrey J. Huda, M. Mamun Huda, Tanvir M. Islam, M. Mofizul Islam, Mohammad Saidul Islam, Rakibul M. Kaambwa, Billingsley Kandel, Himal Kassie, Gizat M. Kelly, Jaimon Terence Kerr, Jessica A. Kiross, Girmay Tsegay Knibbs, Luke D. Kulkarni, Vishnutheertha Vishnutheertha Lalloo, Ratilal Le, Long Khanh Dao Leigh, James Leung, Janni Li, Shanshan Mahumud, Rashidul Alam Mamun, Abdullah A. Marzan, Melvin Barrientos McGrath, John J. Mehlman, Max L. Meretoja, Atte Mersha, Amanual Getnet Miller, Ted R. Mitchell, Philip B. Mokdad, Ali H. Morawska, Lidia Mpundu-Kaambwa, Christine Mude, William Murray, Christopher J. L. Kandel, Sandhya Neupane Nyan Deakin Univ Inst Phys Act & Nutr Melbourne Vic Australia Deakin Univ Sch Exercise & Nutr Sci Melbourne Vic Australia Univ Sydney Sydney Med Sch Sydney NSW Australia Univ Sydney Menzies Ctr Hlth Policy Sydney NSW Australia Univ Sydney Fac Med & Hlth Sydney NSW Australia Univ Sydney Chapter Addict Med Sydney NSW Australia Univ Sydney Sch Publ Hlth Sydney NSW Australia Univ Sydney Save Sight Inst Sydney NSW Australia Univ Sydney Asbestos Dis Res Inst Sydney NSW Australia Univ Sydney NHMRC Clin Trials Ctr Sydney NSW Australia Univ Sydney Sch Vet Sci Sydney NSW Australia Univ Sydney Sydney NSW Australia Univ Queensland Sch Hlth & Rehabil Sci Brisbane Qld Australia Univ Queensland Ctr Sensorimotor Performance Brisbane Qld Australia Univ Queensland Sch Publ Hlth Brisbane Qld Australia Univ Queensland Inst Social Sci Res Brisbane Qld Australia Univ Queensland Sch Dent Brisbane Qld Australia Univ Queensland Queensland Brain Inst Brisbane Qld Australia Univ Queensland Brisbane Qld Australia Monash Univ Sch Publ Hlth & Prevent Med Melbourne Vic Australia Monash Univ Dept Epidemiol & Prevent Med Melbourne Vic Australia Monash Univ Monash Hlth Sch Clin Sci Melbourne Vic Australia Monash Univ Dept Med Melbourne Vic Australia Monash Univ Dept Publ Hlth Melbourne Vic Australia Univ Melbourne Melbourne Sch Populat & Global Hlth Carlton Vic Australia James Cook Univ Publ Hlth & Trop Med Townsville Qld Australia James Cook Univ Coll Publ Hlth Med & Vet Sci Townsville Qld Australia Jashore Univ Sci & Technol Dept Fisheries & Marine Biosci Jashore Bangladesh Australian Natl Univ Res Sch Populat Hlth Canberra ACT Australia Univ Technol Sydney Sch Publ Hlth Sydney NSW Australia Univ Technol Sydney Sch Hlth Sydney NSW Australia Univ Technol Sydney Sch Comp Sci Sydney NSW Australia Murdoch Univ Murdoch Business Sch Perth WA Australia Curtin Univ Fac Hlth Sci Perth WA Australia Curtin Univ Sch Publ Hlth P

Background A comprehensive understanding of temporal trends in the disease burden in Australia is lacking, and these trends are required to inform health service planning and improve population health. We explored the burden and trends of diseases and their risk factors in Australia from 1990 to 2019 through a comprehensive analysis of the Global Burden of Disease Study (GBD) 2019. Methods In this systematic analysis for GBD 2019, we estimated all-cause mortality using the standardised GBD methodology. Data sources included primarily vital registration systems with additional data from sample registrations, censuses, surveys, surveillance, registries, and verbal autopsies. A composite measure of health loss caused by fatal and non-fatal disease burden (disability-adjusted life-years [DALYs]) was calculated as the sum of years of life lost (YLLs) and years of life lived with disability (YLDs). Comparisons between Australia and 14 other high-income countries were made. Findings Life expectancy at birth in Australia improved from 77 center dot 0 years (95% uncertainty interval [UI] 76 center dot 9-77 center dot 1) in 1990 to 82 center dot 9 years (82 center dot 7-83 center dot 1) in 2019. Between 1990 and 2019, the age-standardised death rate decreased from 637 center dot 7 deaths (95% UI 634 center dot 1-641 center dot 3) to 389 center dot 2 deaths (381 center dot 4-397 center dot 6) per 100 000 population. In 2019, non-communicable diseases remained the major cause of mortality in Australia, accounting for 90 center dot 9% (95% UI 90 center dot 4-91 center dot 9) of total deaths, followed by injuries (5 center dot 7%, 5 center dot 3-6 center dot 1) and communicable, maternal, neonatal, and nutritional diseases (3 center dot 3%, 2 center dot 9-3 center dot 7). Ischaemic heart disease, self-harm, tracheal, bronchus, and lung cancer, stroke, and colorectal cancer were the leading causes of YLLs. The leading causes of YLDs were low back pain, depressive disorders, other

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Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021

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LANCET 2024年第10440期403卷 2204-2256页

作者： Vollset, Stein Emil Ababneh, Hazim S. Abate, Yohannes Habtegiorgis Abbafati, Cristiana Abbasgholizadeh, Rouzbeh Abbasian, Mohammadreza Abbastabar, Hedayat Abd Al Magied, Abdallah H. A. Abd ElHafeez, Samar Abdelkader, Atef Abdelmasseh, Michael Abd-Elsalam, Sherief Abdi, Parsa Abdollahi, Mohammad Abdoun, Meriem Abdullahi, Auwal Abebe, Mesfin Abiodun, Olumide Aboagye, Richard Gyan Abolhassani, Hassan Abouzid, Mohamed Aboye, Girma Beressa Abreu, Lucas Guimaraes Absalan, Abdorrahim Abualruz, Hasan Abubakar, Bilyaminu Abukhadijah, Hana Jihad Jihad Addolorato, Giovanni Adekanmbi, Victor Adetunji, Charles Oluwaseun Adetunji, Juliana Bunmi Adeyeoluwa, Temitayo Esther Adha, Rishan Adhikary, Ripon Kumar Adnani, Qorinah Estiningtyas Sakilah Adzigbli, Leticia Akua Afrashteh, Fatemeh Afzal, Muhammad Sohail Afzal, Saira Agbozo, Faith Agodi, Antonella Agrawal, Anurag Agyemang-Duah, Williams Ahinkorah, Bright Opoku Ahlstrom, Austin J. Ahmad, Aqeel Ahmad, Firdos Ahmad, Muayyad M. Ahmad, Sajjad Ahmad, Shahzaib Ahmed, Anisuddin Ahmed, Ayman Ahmed, Haroon Ahmed, Safoora Ahmed, Syed Anees Akinosoglou, Karolina Akkaif, Mohammed Ahmed Akrami, Ashley E. Akter, Ema Al Awaidy, Salah Al Hasan, Syed Mahfuz Al Mosa, Amjad S. Al Ta'ani, Omar Al Zaabi, Omar Ali Mohammed Alahdab, Fares Alajlani, Muaaz M. Al-Ajlouni, Yazan Alalalmeh, Samer O. Al-Aly, Ziyad Alam, Khurshid Alam, Noore Alam, Tahiya Alam, Zufishan Al-Amer, Rasmieh Mustafa Alanezi, Fahad Mashhour Alanzi, Turki M. Albakri, Almaza Aldhaleei, Wafa A. Aldridge, Robert W. Alemohammad, Seyedeh Yasaman Alemu, Yihun Mulugeta Al-Gheethi, Adel Ali Saeed Al-Hanawi, Mohammed Khaled Ali, Abid Ali, Amjad Ali, Iman Ali, Mohammed Usman Ali, Rafat Ali, Syed Shujait Shujait Ali, Victor Ekoche Ali, Waad Al-Ibraheem, Akram Alicandro, Gianfranco Alif, Sheikh Mohammad Aljunid, Syed Mohamed Alla, Francois Almazan, Joseph Uy Al-Mekhlafi, Hesham M. Alqutaibi, Ahmed Yaseen Alrawashdeh, Ahmad Alrousan, Sahel Majed Al-Sabah, Salman Khalifah Alsabri, Mohammed A. Altaany, Zaid Al-Tammemi, Ala'a B. Al-Tawfiq, Jaffa Univ Washington Inst Hlth Metr & Evaluat Seattle WA 98195 USA Univ Washington Sch Med Dept Hlth Metr Sci Seattle WA USA Univ Washington Dept Appl Math Seattle WA USA Univ Washington Sch Med Seattle WA USA Univ Washington Div Pediat Hematol Oncol Seattle WA USA Univ Washington Dept Global Hlth Seattle WA USA Univ Washington Dept Anesthesiol & Pain Med Seattle WA USA Univ Washington Div Plast & Reconstruct Surg Seattle WA USA Univ Washington Henry M Jackson Sch Int Studies Seattle WA USA Norwegian Inst Publ Hlth GBD Collaborating Unit Bergen Norway Norwegian Inst Publ Hlth Dept Dis Burden Bergen Norway Massachusetts Gen Hosp Dept Radiat Oncol Boston MA USA Massachusetts Gen Hosp Dept Orthopaed Surg Boston MA USA Massachusetts Gen Hosp Dept Radiol Boston MA USA Massachusetts Gen Hosp Div Cardiol Boston MA USA Massachusetts Gen Hosp Cardiovasc Res Ctr Boston MA USA Aleta Wondo Hosp Dept Clin Governance & Qual Improvement Aleta Wondo Ethiopia Univ Roma La Sapienza Dept Jurid & Econ Studies Rome Italy Univ Roma La Sapienza Dept Publ Hlth & Infect Dis Rome Italy Univ Calif Los Angeles Doheny Eye Inst Los Angeles CA USA Univ Calif Los Angeles Radiol Dept Los Angeles CA USA Harvard Univ Dept Orthoped Surg Boston MA USA Harvard Univ TH Chan Sch Publ Hlth Boston MA USA Harvard Univ Ctr Primary Care Boston MA USA Harvard Univ Harvard Business Sch Boston MA USA Harvard Univ Div Cardiovasc Med Boston MA USA Harvard Univ Dept Hlth Policy & Oral Epidemiol Boston MA USA Harvard Univ Dept Global Hlth & Social Med Boston MA USA Harvard Univ Beth Israel Deaconess Med Ctr Boston MA USA Shahid Beheshti Univ Med Sci Dept Orthopaed Surg Tehran Iran Shahid Beheshti Univ Med Sci Urol Dept Tehran Iran Shahid Beheshti Univ Med Sci Internal Med Dept SBMU Tehran Iran Shahid Beheshti Univ Med Sci Sch Med Tehran Iran Shahid Beheshti Univ Med Sci Psychiat Nursing & Management Dept Tehran Iran Shahid Beheshti Univ Med Sci Dept Med Genet Tehran

Background Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050. Methods Using forecasts of major drivers of health such as the Socio-demographic Index (SDI;a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. Cause-specific mortality was modelled using mixed-effects models with SDI and time as the main covariates, and the combined impact of causal risk factors as an offset in the model. At the all-cause mortality level, we captured unexplained variation by modelling residuals with an autoregressive integrated moving average model with drift attenuation. These all-cause forecasts constrained the cause-specific forecasts at successively deeper levels of the GBD cause hierarchy using cascading mortality models, thus ensuring a robust estimate of cause-specific mortality. For non-fatal measures (eg, low back pain), incidence and prevalence were forecasted from mixed-effects mode

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Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021

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LANCET NEUROLOGY 2024年第4期23卷 344-381页

作者： Steinmetz, Jaimie D. Seeher, Katrin Maria Schiess, Nicoline Nichols, Emma Cao, Bochen Servili, Chiara Cavallera, Vanessa Cousin, Ewerton Hagins, Hailey Moberg, Madeline E. Mehlman, Max L. Abate, Yohannes Habtegiorgis Abbas, Jaffar Abbasi, Madineh Akram Abbasian, Mohammadreza Abbastabar, Hedayat Abdelmasseh, Michael Abdollahi, Mohammad Abdollahi, Mozhan Abdollahifar, Mohammad-Amin Abd-Rabu, Rami Abdulah, Deldar Morad Abdullahi, Auwal Abedi, Aidin Abedi, Vida Zuniga, Roberto Ariel Abeldano Abidi, Hassan Abiodun, Olumide Aboagye, Richard Gyan Abolhassani, Hassan Aboyans, Victor Abrha, Woldu Aberhe Abualhasan, Ahmed Abu-Gharbieh, Eman Aburuz, Salahdein Adamu, Lawan Hassan Addo, Isaac Yeboah Adebayo, Oladimeji M. Adekanmbi, Victor Adekiya, Tayo Alex Adikusuma, Wirawan Adnani, Qorinah Estiningtyas Sakilah Adra, Saryia Afework, Tsion Afolabi, Aanuoluwapo Adeyimika Afraz, Ali Afzal, Saira Aghamiri, Shahin Agodi, Antonella Agyemang-Duah, Williams Ahinkorah, Bright Opoku Ahmad, Aqeel Ahmad, Danish Ahmad, Sajjad Ahmadzade, Amir Mahmoud Ahmed, Ali Ahmed, Ayman Ahmed, Haroon Ahmed, Jivan Qasim Ahmed, Luai A. Ahmed, Muktar Beshir Ahmed, Syed Anees Ajami, Marjan Aji, Budi Ajumobi, Olufemi Akade, Seyed Esma'il Akbari, Morteza Akbarialiabad, Hossein Akhlaghi, Shiva Akinosoglou, Karolina Akinyemi, Rufus Olusola Akonde, Maxwell Al Hasan, Syed Mahfuz Alahdab, Fares Al-Ahdal, Tareq Mohammed Ali Al-Amer, Rasmieh Mustafa Albashtawy, Mohammed AlBataineh, Mohammad T. Aldawsari, Khalifah A. Alemi, Hediyeh Alemi, Sharifullah Algammal, Abdelazeem M. Al-Gheethi, Adel Ali Saeed Alhalaiqa, Fadwa Alhalaiqa Naji Alhassan, Robert Kaba Ali, Abid Ali, Endale Alemayehu Ali, Liaqat Ali, Mohammed Usman Ali, Musa Mohammed Ali, Rafat Ali, Shahid Ali, Syed Shujait Shujait Ali, Zahid Alif, Sheikh Mohammad Alimohamadi, Yousef Aliyi, Ahmednur Adem Aljofan, Mohamad Aljunid, Syed Mohamed Alladi, Suvarna Almazan, Joseph Uy Almustanyir, Sami Al-Omari, Basem Alqahtani, Jaber S. Alqasmi, Ibrahim Alqutaibi, Ahmed Yaseen Salman, Rustam Al-Shahi Altaany, Zaid Al-Taw Univ Washington Inst Hlth Metr & Evaluat Seattle WA 98105 USA Univ Washington Sch Med Dept Hlth Metr Sci Seattle WA USA Univ Washington Dept Appl Math Seattle WA USA Univ Washington Dept Family Med Seattle WA USA Univ Washington Dept Neurol Surg Seattle WA USA Univ Washington Div Pediat Hematol Oncol Seattle WA USA Univ Washington Dept Epidemiol Seattle WA USA Univ Washington Dept Neurol Seattle WA USA Univ Washington Dept Anesthesiol & Pain Med Seattle WA USA Univ Washington Dept Global Hlth Seattle WA USA Univ Washington Div Plast & Reconstruct Surg Seattle WA USA Univ Washington Hlth Syst & Populat Hlth Seattle WA USA WHO Dept Mental Hlth & Substance Use Geneva Switzerland WHO Dept Data & Analyt Geneva Switzerland Univ Southern Calif Ctr Econ & Social Res Los Angeles CA USA Univ Southern Calif Dept Neurosurg Los Angeles CA USA Univ Southern Calif Keck Sch Med Los Angeles CA USA Univ Southern Calif Dept Radiol Los Angeles CA USA Aleta Wondo Hosp Dept Clin Governance & Qual Improvement Aleta Wondo Ethiopia Shanghai Jiao Tong Univ Mental Hlth Ctr Shanghai Peoples R China Tabriz Univ Med Sci Infect & Trop Res Ctr Tabriz Iran Tabriz Univ Med Sci Dept Radiol Tabriz Iran Tabriz Univ Med Sci Sch Nursing & Midwifery Tabriz Iran Tabriz Univ Med Sci Dept Immunol Tabriz Iran Tabriz Univ Med Sci Dept Community Med Tabriz Iran Tabriz Univ Med Sci Dept Mental Hlth & Psychiat Nursing Tabriz Iran Tabriz Univ Med Sci Drug Appl Res Ctr Tabriz Iran Harvard Univ Dept Orthoped Surg Boston MA USA Harvard Univ Dept Pediat Boston MA USA Harvard Univ TH Chan Sch Publ Hlth Boston MA USA Harvard Univ Ctr Primary Care Boston MA USA Harvard Univ Harvard Business Sch Boston MA USA Harvard Univ Div Cardiovasc Med Boston MA USA Harvard Univ Div Cardiol Boston MA USA Harvard Univ Dept Hlth Policy & Oral Epidemiol Boston MA USA Harvard Univ Dept Phys Med & Rehabil Boston MA USA Shahid Beheshti Univ Med Sci Dept Orthopaed Surg Tehran I

Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021. Methods We estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous sys

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Muscle innervation patterns for human wrist control: useful biofeedback signals for robotic rehabilitation? 14

Muscle innervation patterns for human wrist control: useful ...

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14th IEEE/RAS-EMBS International Conference on Rehabilitation Robotics (ICORR)

作者： Semprini, M. Cuppone, A. Squeri, V. Konczak, J. Ist Italiano Tecnol HT Ctr Neurosci & Cognit Syst UniTn Rovereto Italy Ist Italiano Tecnol HT Robot Brain and Cognit Sci Genoa Italy Univ Minnesota Human Sensorimotor Control Lab Ctr Clin Movement Sci Minneapolis MN 55455 USA Univ Minnesota Sch Kinesiol Minneapolis MN 55455 USA

ISBN: (纸本)9781479918089

Upper limb robotic rehabilitation technology has recognized the importance of biofeedback signals for optimizing motor recovery. Impaired motor control is typically associated with abnormal muscle activation patterns and such patterns can be revealed by electromyography (EMG). However, before using user-generated EMG signals as biofeedback for controlling and optimizing force output of a robot, it is imperative that the healthy muscle innervation patterns are fully established to guide possible robot-aided rehabilitation protocols. Given the muscular redundancy found in many human limb systems, and given that force generation of human muscles is not linear, it becomes important to understand how synergistic control influences joint force and joint kinematics. It is the purpose of this study to map the electromyographic activation patterns of the major human muscles involved in controlling the hand/wrist system. By means of a robotic exoskeleton three Degrees of Freedom (DoF) were evaluated: wrist flexion-extension and adduction abduction as well as forearm pronation-supination separately and for different ranges of the workspace. We recorded EMG activity of 7 arm muscles of 4 healthy subjects performing the task and we therefore defined the typical EMI: activation patterns of such muscles during robotic training.

关键词： biofeedback electromyography muscle activation wrist movement wrist exoskeleton

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Robot-assisted training to improve proprioception does benefit from added vibro-tactile feedback 37

Robot-assisted training to improve proprioception does benef...

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37th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC)

作者： Cuppone, A. Squeri, V. Semprini, M. Konczak, J. Ist Italiano Tecnol RBCS Dept I-3016163 Genoa Italy Ist Italiano Tecnol Ctr Neurosci & Cognit Syst UniTn I-38068 Rovereto Italy Univ Minnesota Human Sensorimotor Control Lab Ctr Clin Movement Sci Minneapolis MN 55455 USA Univ Minnesota Sch Kinesiol Minneapolis MN 55455 USA

ISBN: (纸本)9781424492701

Proprioception is central for motor control and its role must also be taken into account when designing motor rehabilitation training protocols. This is particularly important when dealing with motor deficits due to proprioceptive impairment such as peripheral sensory neuropathy. In these cases substituting or augmenting diminished proprioceptive sensory information might be beneficial for improving motor function. However it still remains to be understood how proprioceptive senses can be improved by training, how this would translate into motor improvement and whether additional sensory modalities during motor training contribute to the sensorimotor training process. This preliminary study investigated how proprioceptive/haptic training can be augmented by providing additional sensory information in the form of vibro-tactile feedback. We tested the acuity of the wrist proprioceptive position sense before and after robotic training in two groups of healthy subjects, one trained only with haptic feedback and one with haptic and vibro-tactile feedback. We found that only the group receiving the multimodal feedback significantly improved proprioceptive acuity. This study demonstrates that non-proprioceptive position feedback derived from another somatosensory modality is easily interpretable for humans and can contribute to an increased precision of joint position. The clinical implications of this finding will be outlined.

关键词： Robot-assisted training improve proprioception benefit from added vibro-tactile feedback

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Proprioceptive assessment of the wrist joint across both joint degrees of freedom 14

Proprioceptive assessment of the wrist joint across both joi...

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14th IEEE/RAS-EMBS International Conference on Rehabilitation Robotics (ICORR)

作者： Cuppone, A. Squeri, V. Semprini, M. Konczak, J. Ist Italiano Tecnol IIT Robot Brain & Cognit Sci Genoa Italy Ist Italiano Tecnol IIT Ctr Neurosci & Cognit Syst UniTn Genoa Italy Univ Minnesota Human Sensorimotor Control Lab Ctr Clin Movement Sci Minneapolis MN 55455 USA Univ Minnesota Sch Kinesiol Minneapolis MN 55455 USA

ISBN: (纸本)9781479918089

Neurological movement disorders such as stroke or sensory neuropathy are associated with somatosensory deficits. From a neurorehabilitation perspective, the assessment of proprioceptive function is important for planning and applying adequate rehabilitation treatments. Numerous behavioral and psychophysical methods arc available to measure proprioceptive acuity. However, no universally accepted and adopted protocol exists. In recent years robotic devices have increasingly been used to investigate and assess proprioceptive function, but few studies have focused on the wrist joint. To fill this knowledge gap, this study aimed to systematically map the proprioceptive acuity of the wrist for its two joint degrees of freedom (DoF) flexion/extension (FE) and abduction/adduction (AA). Twenty eight healthy young adults performed an ipsilateral, active joint position matching task using a robotic device. As a measure of proprioceptive acuity we determined the error between target position and the matched joint position. Results showed that: first, proprioceptive acuity varied between the two joint DoF with the matching error for AA being lower than the FE. Second, within each DoF, the motion direction did not affect the accuracy. Third, the radial component of the matching error showed DoF dependence: the FE movements tended to undershoot, while the AA movement overshot the target position. Results are indicative of a joint DoF dependent anisotropy of wrist proprioceptive acuity.

关键词： joint position sense proprioceptive acuity wrist robotic assessment

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Hand synergies: Integration of robotics and neuroscience for understanding the control of biological and artificial hands

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PHYSICS OF LIFE REVIEWS 2016年 17卷 1-23页

作者： Santello, Marco Bianchi, Matteo Gabiccini, Marco Ricciardi, Emiliano Salvietti, Gionata Prattichizzo, Domenico Ernst, Marc Moscatelli, Alessandro Jorntell, Henrik Kappers, Astrid M. L. Kyriakopoulos, Kostas Albu-Schaeffer, Alin Castellini, Claudio Bicchi, Antonio Arizona State Univ Sch Biol & Hlth Syst Engn 501 East Tyler MallECG BldgSuite 334 Tempe AZ 85287 USA Univ Pisa Res Ctr E Piaggio Largo Lucio Lazzarino 1 I-56122 Pisa Italy Ist Italiano Tecnol Adv Robot Dept Genoa Italy Univ Pisa Dept Civil & Ind Engn Pisa Italy Univ Pisa Dept Surg Med Mol Pathol & Crit Care Mol Mind Lab I-56122 Pisa Italy Univ Siena Dept Informat Engn & Math Siena Italy Univ Bielefeld Dept Cognit Neurosci Bielefeld Germany Univ Bielefeld CITEC Bielefeld Germany Univ Roma Tor Vergata Dept Syst Med I-00173 Rome Italy Univ Roma Tor Vergata Ctr Space Biomed I-00173 Rome Italy Lund Univ Dept Expt Med Sci Neural Basis Sensorimotor Control Lund Sweden Vrije Univ Amsterdam Human Movement Sci Amsterdam Netherlands Natl Tech Univ Athens Sch Mech Engn GR-10682 Athens Greece DLR German Aerosp Ctr Inst Robot & Mechatron Oberpfaffenhofen Germany

The term 'synergy' from the Greek synergia means 'working together'. The concept of multiple elements working together towards a common goal has been extensively used in neuroscience to develop theoretical frameworks, experimental approaches, and analytical techniques to understand neural control of movement, and for applications for neuro-rehabilitation. In the past decade, roboticists have successfully applied the framework of synergies to create novel design and control concepts for artificial hands, i.e., robotic hands and prostheses. At the same time, robotic research on the sensorimotor integration underlying the control and sensing of artificial hands has inspired new research approaches in neuroscience, and has provided useful instruments for novel experiments. The ambitious goal of integrating expertise and research approaches in robotics and neuroscience to study the properties and applications of the concept of synergies is generating a number of multidisciplinary cooperative projects, among which the recently finished 4-year European project "The Hand Embodied" (THE). This paper reviews the main insights provided by this framework. Specifically, we provide an overview of neuroscientific bases of hand synergies and introduce how robotics has leveraged the insights from neuroscience for innovative design in hardware and controllers for biomedical engineering applications, including myoelectric hand prostheses, devices for haptics research, and wearable sensing of human hand kinematics. The review also emphasizes how this multidisciplinary collaboration has generated new ways to conceptualize a synergy-based approach for robotics, and provides guidelines and principles for analyzing human behavior and synthesizing artificial robotic systems based on a theory of synergies. (C) 2016 Elsevier B.V. All rights reserved.

关键词： Movement Force Biomechanics Electromyography Motor control

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Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019

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LANCET NEUROLOGY 2021年第10期20卷 795-820页

作者： Feigin, Valery L. Stark, Benjamin A. Johnson, Catherine Owens Roth, Gregory A. Bisignano, Catherine Abady, Gdiom Gebreheat Abbasifard, Mitra Abbasi-Kangevari, Mohsen Abd-Allah, Foad Abedi, Vida Abualhasan, Ahmed Abu-Rmeileh, Niveen Me Abushouk, Abdelrahman, I Adebayo, Oladimeji M. Agarwal, Gina Agasthi, Pradyumna Ahinkorah, Bright Opoku Ahmad, Sohail Ahmadi, Sepideh Salih, Yusra Ahmed Aji, Budi Akbarpour, Samaneh Akinyemi, Rufus Olusola Al Hamad, Hanadi Alahdab, Fares Alif, Sheikh Mohammad Alipour, Vahid Aljunid, Syed Mohamed Almustanyir, Sami Al-Raddadi, Rajaa M. Salman, Rustam Al-Shahi Alvis-Guzman, Nelson Ancuceanu, Robert Anderlini, Deanna Anderson, Jason A. Ansar, Adnan Antonazzo, Ippazio Cosimo Arabloo, Jalal Arnlov, Johan Artanti, Kurnia Dwi Aryan, Zahra Asgari, Samaneh Ashraf, Tahira Athar, Mohammad Atreya, Alok Ausloos, Marcel Baig, Atif Amin Baltatu, Ovidiu Constantin Banach, Maciej Barboza, Miguel A. Barker-Collo, Suzanne Lyn Barnighausen, Till Winfried Barone, Mark Thomaz Ugliara Basu, Sanjay Bazmandegan, Gholamreza Beghi, Ettore Beheshti, Mahya Bejot, Yannick Bell, Arielle Wilder Bennett, Derrick A. Bensenor, Isabela M. Bezabhe, Woldesellassie Mequanint Bezabih, Yihienew Mequanint Bhagavathula, Akshaya Srikanth Bhardwaj, Pankaj Bhattacharyya, Krittika Bijani, Ali Bikbov, Boris Birhanu, Mulugeta M. Boloor, Archith Bonny, Aime Brauer, Michael Brenner, Hermann Bryazka, Dana Butt, Zahid A. dos Santos, Florentino Luciano Caetano Campos-Nonato, Ismael R. Cantu-Brito, Carlos Carrero, Juan J. Castaneda-Orjuela, Carlos A. Catapano, Alberico L. Chakraborty, Promit Ananyo Charan, Jaykaran Choudhari, Sonali Gajanan Chowdhury, Enayet Karim Chu, Dinh-Toi Chung, Sheng-Chia Colozza, David Costa, Vera Marisa Costanzo, Simona Criqui, Michael H. Dadras, Omid Dagnew, Baye Dai, Xiaochen Dalal, Koustuv Damasceno, Albertino Antonio Moura D'Amico, Emanuele Dandona, Lalit Dandona, Rakhi Gela, Jiregna Darega Davletov, Kairat De La Cruz-Gongora, Vanessa Desai, Rupak Dhamnetiya, Deepak Dharmaratne, Samath Dhamminda Dhimal, Mand Auckland Univ Technol Natl Inst Stroke & Appl Neurosci Auckland New Zealand Univ Washington Inst Hlth Metr & Evaluat Seattle WA 98195 USA Univ Washington Div Cardiol Sch Med Seattle WA USA Univ Washington Sch Med Dept Hlth Metr Sci Seattle WA USA Univ Washington Dept Neurol Surg Seattle WA 98195 USA Univ Washington Dept Neurol Seattle WA USA Univ Washington Dept Anesthesiol & Pain Med Seattle WA USA Res Ctr Neurol Dept Neurol 3 Moscow Russia Res Ctr Neurol Moscow Russia Adigrat Univ Dept Nursing Adigrat Ethiopia Rafsanjan Univ Med Sci Dept Internal Med Rafsanjan Iran Rafsanjan Univ Med Sci Clin Res Dev Unit Rafsanjan Iran Rafsanjan Univ Med Sci Family Med Dept Rafsanjan Iran Rafsanjan Univ Med Sci Dept Neurol Rafsanjan Iran Rafsanjan Univ Med Sci Noncommunicable Dis Res Ctr Rafsanjan Iran Shahid Beheshti Univ Med Sci Social Determinants Hlth Res Ctr Tehran Iran Shahid Beheshti Univ Med Sci Sch Adv Technol Med Tehran Iran Shahid Beheshti Univ Med Sci Prevent Metab Disorders Res Ctr Tehran Iran Cairo Univ Dept Neurol Cairo Egypt Geisinger Hlth Syst Dept Mol & Funct Genom Danville PA USA Geisinger Hlth Syst Dept Neurosci Danville PA USA Virginia Tech Biocomplex Inst Blacksburg VA USA Birzeit Univ Inst Community & Publ Hlth Ramallah Palestine Harvard Univ Harvard Med Sch Boston MA 02115 USA Harvard Univ Brigham & Womens Hosp Boston MA 02115 USA Harvard Univ TH Chan Sch Publ Hlth Boston MA 02115 USA Harvard Univ Ctr Primary Care Boston MA 02115 USA Harvard Univ Dept Global Hlth & Social Med Boston MA 02115 USA Harvard Univ Div Cardiol Boston MA 02115 USA Harvard Univ Dept Med Boston MA 02115 USA Harvard Univ Dept Internal Med Boston MA 02115 USA Harvard Univ Div Gen Internal Med Boston MA 02115 USA Ain Shams Univ Dept Med Cairo Egypt Ain Shams Univ Neurol Dept Cairo Egypt Ain Shams Univ Dept Entomol Cairo Egypt Univ Coll Hosp Coll Med Ibadan Nigeria Univ Coll Hosp Dept Community Med Ibadan Nigeria Univ Coll

Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]) associated with 19 risk factors, for 204 countries and territories from 1990 to 2019. These estimates were provided for ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and all strokes combined, and stratified by sex, age group, and World Bank country income level. Findings In 2019, there were 12.2 million (95% UI 11.0-13.6) incident cases of stroke, 101 million (93.2-111) prevalent cases of stroke, 143 million (133-153) DALYs due to stroke, and 6.55 million (6.00-7.02) deaths from stroke. Globally, stroke remained the second-leading cause of death (11.6% [10.8-12.2] of total deaths) and the third-leading cause of death and disability combined (5.7% [5.1-6.2] of total DALYs) in 2019. From 1990 to 2019, the absolute number of incident strokes increased by 70.0% (67.0-73.0), prevalent strokes increased by 85.0% (83.0-88.0), deaths from stroke increased by 43.0% (31.0-55.0), and DALYs due to stroke increased by 32.0% (22.0-42.0). During the same period, age-standardised rates of stroke incidence decreased by 17.0% (15.0-18.0), mortality decreased by 36.0% (31.0-42.0), prevalence decreased by 6.0% (5.0-7.0), and DALYs decreased by 36.0% (31.0-42.0). However, among people younger than 70 years, prevalence rates increased by 22.0% (21.0-24.0) and incidence rates

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Robot-assisted training to improve proprioception does benefit from added vibro-tactile feedback

Robot-assisted training to improve proprioception does benef...

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Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

作者： A. Cuppone V. Squeri M. Semprini J. Konczak RBCS Department of Istituto Italiano di Tecnologia Genova Italy Center for Neuroscience and Cognitive System @UniTn Istituto Italiano di Tecnologia Rovereto Italy Human Sensorimotor Control Lab University of Minnesota Minneapolis USA

关键词： Training Haptic interfaces Wrist Joints Robot sensing systems Vibrations

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Proprioceptive assessment of the wrist joint across both joint degrees of freedom

Proprioceptive assessment of the wrist joint across both joi...

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IEEE International Conference on Rehabilitation Robotics (ICORR)

作者： A. Cuppone V. Squeri M. Semprini J. Konczak Robotics Brain and Cognitive Sciences Istituto Italiano di Tecnologia (IIT) Genoa Italy Center for Neuroscience and Cognitive Systems @UniTn Italiano di Tecnologia (lIT) marianna Italy Human Sensorimotor Control Lab University of Minnesota USA

ISBN: (纸本)9781479918096

Neurological movement disorders such as stroke or sensory neuropathy are associated with somatosensory deficits. From a neurorehabilitation perspective, the assessment of proprioceptive function is important for planning and applying adequate rehabilitation treatments. Numerous behavioral and psychophysical methods are available to measure proprioceptive acuity. However, no universally accepted and adopted protocol exists. In recent years robotic devices have increasingly been used to investigate and assess proprioceptive function, but few studies have focused on the wrist joint. To fill this knowledge gap, this study aimed to systematically map the proprioceptive acuity of the wrist for its two joint degrees of freedom (DoF) - flexion/extension (FE) and abduction/adduction (AA). Twenty eight healthy young adults performed an ipsilateral, active joint position matching task using a robotic device. As a measure of proprioceptive acuity we determined the error between target position and the matched joint position. Results showed that: first, proprioceptive acuity varied between the two joint DoF with the matching error for AA being lower than the FE. Second, within each DoF, the motion direction did not affect the accuracy. Third, the radial component of the matching error showed DoF dependence: the FE movements tended to undershoot, while the AA movement overshot the target position. Results are indicative of a joint DoF dependent anisotropy of wrist proprioceptive acuity.

关键词： Joints Wrist Robot sensing systems Ligaments Position measurement Iron

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