The interaction between thiazolo[2,3-b]pyrimidine (TZPM) analogues and bovine serum albumin (BSA) was investigated by fluorescence and UV–Vis *** experiment was explored at two different temperatures (299 and 307 K) ...
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The interaction between thiazolo[2,3-b]pyrimidine (TZPM) analogues and bovine serum albumin (BSA) was investigated by fluorescence and UV–Vis *** experiment was explored at two different temperatures (299 and 307 K) under imitated physiological *** results indicated that TZPM caused the fluorescence quenching of BSA through a combined quenching *** the spectra obtained,the binding constant (Ka),binding sites (n) at different temperatures were *** on the F?rster non-radiation energy transfer theory,the average binding distance between BSA and TZPM was *** synchronous fluorescence spectra indicated that the conformation of BSA has been *** comparison of binding potency of TZPM and BSA suggested that the substituent on the benzene ring enhance the binding affinity of TZPM and *** investigated the possible sub-domain on BSA where bind TZPM by displacement ***,to explore the effect of molecular structure on the binding,a study on quantitative structure-property relationship (QSPR) was performed.
The interaction between 3-spiro-2'-pyrrolidine-3'-spiro-3"-piperidine-2,3"-dione(PPD) and bovine serum albumin (BSA) in aqueous solution has been studied using fluorescence and UV–vi...
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The interaction between 3-spiro-2'-pyrrolidine-3'-spiro-3"-piperidine-2,3"-dione(PPD) and bovine serum albumin (BSA) in aqueous solution has been studied using fluorescence and UV–vis spectroscopy in this *** emission data revealed that BSA (1.00×10-5 mol·L-1) fluorescence was statically quenched by PPD at various concentrations,which implies that PPD–BSA complex has been *** binding constant (KA * Corresponding ***.: +86-731-58290187; Fax: +86-731-58290509.) was calculate,the individual values had been compared as in the following order: compound 4 < compound 3 < compound 2 < compound 1 at different temperatures,and had a discussion on different results when the four aimed compounds interacted with *** number of binding sites (n) and the specific binding sites of the PPD with BSA were ***–transfer efficiency parameters were analyzed,moreover,the distance (r) between BSA and PPD had been compared to illustrate the interaction between different PPD and *** to van’t Hoff equation,the thermodynamic parameters,ΔG,ΔH and ΔS,were obtained,ΔH>0,ΔS>0,showing that the involvement of hydrophobic force in these interactions; ΔG<0,indicated the binding of PPD with BSA is *** synchronous fluorescence of BSA was affected by compounds which had slight blue or red shift which showed that PPD had caused some structural changes to BSA.
Complex networks have recently attracted much attention in diverse areas of science and technology. Many networks such as the WWW and biological networks are known to display spatial heterogeneity which can be charact...
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It is shown that the conforming Q2,1;1,2-Q'1 mixed element is stable, and provides optimal order of approximation for the Stokes equations on rectangular grids. Here, Q2,1;1,2 = Q2,1 × Q1,2, and Q2,1 denotes ...
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It is shown that the conforming Q2,1;1,2-Q'1 mixed element is stable, and provides optimal order of approximation for the Stokes equations on rectangular grids. Here, Q2,1;1,2 = Q2,1 × Q1,2, and Q2,1 denotes the space of continuous piecewise-polynomials of degree 2 or less in the x direction but of degree 1 in the y direction. Q'1 is the space of discontinuous bilinear polynomials, with spurious modes filtered. To be precise, Q'1 is the divergence of the discrete velocity space Q2,1;1,2. Therefore, the resulting finite element solution for the velocity is divergence-free pointwise, when solving the Stokes equations. This element is the lowest order one in a family of divergence-free element, similar to the families of the Bernardi-Raugel element and the RaviartThomas element.
In this paper,we investigate the dependence of the solutions on the parameters(order,initial function,right-hand function)of fractional delay differential equations(FDDEs)with the Caputo fractional *** results includi...
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In this paper,we investigate the dependence of the solutions on the parameters(order,initial function,right-hand function)of fractional delay differential equations(FDDEs)with the Caputo fractional *** results including an estimate of the solutions of FDDEs are given *** results are verified by some numerical examples.
In this paper,we apply an a posteriori error control theory that we develop in a very recent paper to three families of the discontinuous Galerkin methods for the Reissner-Mindlin plate *** derive robust a posteriori ...
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In this paper,we apply an a posteriori error control theory that we develop in a very recent paper to three families of the discontinuous Galerkin methods for the Reissner-Mindlin plate *** derive robust a posteriori error estimators for them and prove their reliability and efficiency.
In this paper,we discuss the a posteriori error estimates of the mixed finite element method for quadratic optimal control problems governed by linear parabolic *** state and the co-state are discretized by the high o...
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In this paper,we discuss the a posteriori error estimates of the mixed finite element method for quadratic optimal control problems governed by linear parabolic *** state and the co-state are discretized by the high order Raviart-Thomas mixed finite element spaces and the control is approximated by piecewise constant *** derive a posteriori error estimates for both the state and the control *** estimates,which are apparently not available in the literature,are an important step towards developing reliable adaptive mixed finite element approximation schemes for the control problem.
We study the formation of stable homonuclear and heteronuclear pentamers from ultracold atoms via a generalized stimulated Raman adiabatic passage scheme. The atom-molecule dark-state solutions for the system are obta...
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We study the formation of stable homonuclear and heteronuclear pentamers from ultracold atoms via a generalized stimulated Raman adiabatic passage scheme. The atom-molecule dark-state solutions for the system are obtained, and the linear instability and the adiabatic fidelity of the dark state are investigated. We also discuss the effects of external field parameters on the conversion efficiency.
The 1,3-dipolar cycloaddition of an azomethine ylide generated by a decarboxylative route from sarcosine and acenaphthenequinone to 7-arylmethylidene-3-aryl-3,4-dihydro-2H-thiazolo[3,2-aJ[1,3,5]triazin-6（7H）-ones af...
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The 1,3-dipolar cycloaddition of an azomethine ylide generated by a decarboxylative route from sarcosine and acenaphthenequinone to 7-arylmethylidene-3-aryl-3,4-dihydro-2H-thiazolo[3,2-aJ[1,3,5]triazin-6（7H）-ones afforded novel dispiro[acenaphthylene-1,2’-pyrrolidine]-3＇,7″-[1,3]thiazolo[3,2-a][1,3,5]triazines in moderate yields. The structures of the products were determined and characterized thoroughly by NMR, MS, IR, elemental analysis and X-ray crystallographic analysis. The results of experiment indicated that this 1,3-dipolar cycloaddition proceeded with high stereoselectivity and regioselectivity.
The 1,3-dipolar cycloaddition reactions of nitrilimine with thiazolo[3,2-a]pyrimidine derivatives was investigated. Bis-cycloadducts were obtained through a domino 1,3-dipolar cycloaddition/ring-opening/ring-opening/ ...
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The 1,3-dipolar cycloaddition reactions of nitrilimine with thiazolo[3,2-a]pyrimidine derivatives was investigated. Bis-cycloadducts were obtained through a domino 1,3-dipolar cycloaddition/ring-opening/ring-opening/ 1,3-dipolar cycloaddition processes. The structures of the products were characterized thoroughly by NMR, IR, MS, elemental analysis together with X-ray crystallographic analysis.
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