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arXiv 2024年

作者： Zhang, Jinwei Zuo, Lianrui Liu, Yihao Remedios, Samuel Landman, Bennett A. Prince, Jerry L. Carass, Aaron Image Analysis and Communications Laboratory Department of Electrical and Computer Engineering Johns Hopkins University BaltimoreMD21218 United States Department of Electrical and Computer Engineering Vanderbilt University NashvilleTN37235 United States Department of Computer Science Johns Hopkins University BaltimoreMD21218 United States

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often complicates these analysis, particularly in brain parcellation. Lesion filling is commonly used to mitigate this issue, but existing lesion filling algorithms often fall short in accurately reconstructing realistic lesion-free images, which are vital for consistent downstream analysis. Additionally, the performance of lesion segmentation algorithms is often limited by insufficient data with lesion delineation as training labels. In this paper, we propose a novel approach leveraging Denoising Diffusion Implicit Models (DDIMs) for both MS lesion filling and synthesis based on image inpainting. Our modified DDIM architecture, once trained, enables both MS lesion filing and synthesis. Specifically, it can generate lesion-free T1-weighted or FLAIR images from those containing lesions;Or it can add lesions to T1-weighted or FLAIR images of healthy subjects. The former is essential for downstream analyses that require lesion-free images, while the latter is valuable for augmenting training datasets for lesion segmentation tasks. We validate our approach through initial experiments in this paper and demonstrate promising results in both lesion filling and synthesis, paving the way for future work. Our code is available at https://***/IACL/UponAcceptance. © 2024, CC BY.

关键词： image segmentation

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Unsupervised learning of spatially varying regularization for diffeomorphic image registration

arXiv

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arXiv 2024年

作者： Chen, Junyu Wei, Shuwen Liu, Yihao Bian, Zhangxing He, Yufan Carass, Aaron Bai, Harrison Du, Yong Department of Radiology and Radiological Science Johns Hopkins School of Medicine MD United States Image Analysis and Communications Laboratory Department of Electrical and Computer Engineering Johns Hopkins University MD United States Department of Electrical and Computer Engineering Vanderbilt University TN United States NVIDIA Corporation BethesdaMD United States

Spatially varying regularization accommodates the deformation variations that may be necessary for different anatomical regions during deformable image registration. Historically, optimization-based registration models have harnessed spatially varying regularization to address anatomical subtleties. However, most modern deep learning-based models tend to gravitate towards spatially invariant regularization, wherein a homogenous regularization strength is applied across the entire image, potentially disregarding localized variations. In this paper, we propose a hierarchical probabilistic model that integrates a prior distribution on the deformation regularization strength, enabling the end-to-end learning of a spatially varying deformation regularizer directly from the data. The proposed method is straightforward to implement and easily integrates with various registration network architectures. Additionally, automatic tuning of hyperparameters is achieved through Bayesian optimization, allowing efficient identification of optimal hyperparameters for any given registration task. Comprehensive evaluations on publicly available datasets demonstrate that the proposed method significantly improves registration performance and enhances the interpretability of deep learning-based registration, all while maintaining smooth deformations. Copyright © 2024, The Authors. All rights reserved.

关键词： image registration

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Unique MS Lesion Identification from MRI

arXiv

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arXiv 2024年

作者： Rivas, Carlos A. Zhang, Jinwei Wei, Shuwen Remedios, Samuel W. Carass, Aaron Prince, Jerry L. Image Analysis and Communications Laboratory Dept. of Electrical and Computer Engineering Johns Hopkins University BaltimoreMD21218 United States Dept. of Computer Science Johns Hopkins University BaltimoreMD21218 United States

Unique identification of multiple sclerosis (MS) white matter lesions (WMLs) is important to help characterize MS progression. WMLs are routinely identified from magnetic resonance images (MRIs) but the resultant total lesion load does not correlate well with EDSS∗;whereas mean unique lesion volume has been shown to correlate with EDSS. Our approach builds on prior work by incorporating Hessian matrix computation from lesion probability maps before using the random walker algorithm to estimate the volume of each unique lesion. Synthetic images demonstrate our ability to accurately count the number of lesions present. The takeaways, are: 1) that our method correctly identifies all lesions including many that are missed by previous methods;2) we can better separate confluent lesions;and 3) we can accurately capture the total volume of WMLs in a given probability map. This work will allow new more meaningful statistics to be computed from WMLs in brain MRIs. © 2024, CC BY.

关键词： Magnetic resonance imaging

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Dermoscopic image Classification Using Attention Mechanism and Ensemble Learning Approaches

Dermoscopic Image Classification Using Attention Mechanism a...

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2023 IEEE International Conference on Big Data, BigData 2023

作者： Huang, Shanchuan Lei, Hongwei Jin, Liuhan Yang, Jinzhu Jiang, Tao Yao, Yudong Grzegorzek, Marcin Li, Chen Northeastern University Microscopic Image and Medical Image Analysis Group College of Medicine and Biological Information Engineering China Northeastern University Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Liaoning Shenyang China Chengdu University of Traditional Chinese Medicine School of Intelligent Medicine Chengdu China Stevens Institute of Technology Department of Electrical and Computer Engineering United States Institute of Medical Informatics University of Luebeck Luebeck Germany

ISBN: (纸本)9798350324457

Background and purpose: Skin tumours have become one of the most common diseases worldwide. While benign ones are not usually a threat to human health, malignant ones can develop into skin cancer and become life-threatening if left untreated. Early detection of the disease is important for the treatment of patients with skin tumours and dermoscopy is the most effective means of diagnosing skin tumours. However, the complexity of skin tumour cells makes the diagnosis somewhat erroneous for doctors. Therefore, a dermoscopic classification network based on deep learning and computer-aided diagnostic techniques is needed to obtain a high diagnostic accuracy rate for skin tumours. Methods: In this paper, Deep-skin, a model for dermoscopic image classification is proposed, which is based on both attention mechanism and ensemble learning. Considering the characteristics of dermoscopic images, embedding different attention mechanisms on top of Inception-V3 has been suggested to obtain more potential features. We then improve the classification performance by late fusion of the different models. To demonstrate the effectiveness of Deep-skin, experiments and evaluations are performed on the publicly available dataset Skin Cancer: Malignant vs. Benign and compare the performance of Deep-skin with other classification models. Results: The experimental results indicate that Deep-skin performs well on the dataset in comparison to other models, achieving a maximum accuracy of 87.8%.Conclusion: In this paper, the Deep-skin model is proposed for the classification of dermoscopic images and has shown better performance. In the future, we intend to investigate better classification models for automatic diagnosis of skin tumours. Such models can potentially assist physicians and patients in clinical settings. © 2023 IEEE.

关键词： Attention mechanism Ensemble learning image classification Late fusion Skin Cancer

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Beyond MR image Harmonization: Resolution Matters Too

arXiv

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arXiv 2024年

作者： Hays, Savannah P. Remedios, Samuel W. Zuo, Lianrui Mowry, Ellen M. Newsome, Scott D. Calabresi, Peter A. Carass, Aaron Dewey, Blake E. Prince, Jerry L. Image Analysis and Communications Laboratory Department of Electrical and Computer Engineering Johns Hopkins University BaltimoreMD21218 United States Department of Computer Science Johns Hopkins University BaltimoreMD21218 United States Department of Electrical and Computer Engineering Vanderbilt University NashvilleTN37235 United States Department of Neurology Johns Hopkins School of Medicine BaltimoreMD21287 United States

Magnetic resonance (MR) imaging is commonly used in the clinical setting to non-invasively monitor the body. There exists a large variability in MR imaging due to differences in scanner hardware, software, and protocol design. Ideally, a processing algorithm should perform robustly to this variability, but that is not always the case in reality. This introduces a need for image harmonization to overcome issues of domain shift when performing downstream analysis such as segmentation. Most image harmonization models focus on acquisition parameters such as inversion time or repetition time, but they ignore an important aspect in MR imaging—resolution. In this paper, we evaluate the impact of image resolution on harmonization using a pretrained harmonization algorithm. We simulate 2D acquisitions of various slice thicknesses and gaps from 3D acquired, 1mm3 isotropic MR images and demonstrate how the performance of a state-of-the-art image harmonization algorithm varies as resolution changes. We discuss the most ideal scenarios for image resolution including acquisition orientation when 3D imaging is not available, which is common for many clinical scanners. Our results show that harmonization on low-resolution images does not account for acquisition resolution and orientation variations. Super-resolution can be used to alleviate resolution variations but it is not always used. Our methodology can generalize to help evaluate the impact of image acquisition resolution for multiple tasks. Determining the limits of a pretrained algorithm is important when considering preprocessing steps and trust in the results. Copyright © 2024, The Authors. All rights reserved.

关键词： Magnetic resonance imaging

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ISGAN: Unsupervised Domain Adaptation With Improved Symmetric GAN for Cross-Modality Multi-Organ Segmentation

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IEEE Journal of Biomedical and Health Informatics 2024年第6期29卷 3874-3885页

作者： Jiapeng Li Yifan Zhang Lisheng Xu Yudong Yao Lin Qi College of Medicine and Biological Information Engineering Northeastern University Shenyang China Engineering Research Center of Medical Imaging and Intelligent Analysis Ministry of Education Shenyang China Key Laboratory of Medical Image Computing Ministry of Education Northeastern University Shenyang China Department of Electrical and Computer Engineering Stevens Institute of Technology Hoboken NJ USA

The differences between cross-modality medical images are significant, so several studies are working on unsupervised domain adaptation (UDA) segmentation, which aims to adapt a segmentation model trained on a labeled source domain to an unlabeled target domain. The conventional UDA segmentation strategy aims to integrate image generation and segmentation. However, conventional image generation modules only consider information from a single domain (source or target), resulting in visual inconsistencies. The image generation module may also lack anatomical constraints, leading to incorrect pseudo-label generation. To address these issues, we propose an improved symmetric generative adversarial network (ISGAN). Unlike conventional approaches that perform domain adaptation only in the source or target domain, ISGAN adopts a symmetric architecture using two-path domain adaptation to reduce the visual difference. In addition, ISGAN adopts a bidirectional training strategy to optimize the image generation and segmentation modules. The bidirectional training strategy introduces the anatomical constraints into the image generation module, thereby reducing the generation of incorrect pseudo labels. Finally, we validate ISGAN on two cross-modality datasets (the MMWHS cardiac dataset and Abdomen dataset). ISGAN delivers promising segmentation and generalization performance compared with state-of-the-art UDA methods.

关键词： image segmentation Training Biomedical imaging image synthesis Magnetic resonance imaging Computed tomography Feature extraction Generative adversarial networks Generators Diffusion models

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GEM: Context-Aware Gaze EstiMation with Visual Search Behavior Matching for Chest Radiograph

arXiv

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arXiv 2024年

作者： Liu, Shaonan Chen, Wenting Liu, Jie Luo, Xiaoling Shen, Linlin Computer Vision Institute College of Computer Science and Software Engineering Shenzhen University China Department of Electrical Engineering City University of Hong Kong Hong Kong AI Research Center for Medical Image Analysis and Diagnosis Shenzhen University China Guangdong Provincial Key Laboratory of Intelligent Information Processing China

Gaze estimation is pivotal in human scene comprehension tasks, particularly in medical diagnostic analysis. Eye-tracking technology facilitates the recording of physicians’ ocular movements during image interpretation, thereby elucidating their visual attention patterns and information-processing strategies. In this paper, we initially define the context-aware gaze estimation problem in medical radiology report settings. To understand the attention allocation and cognitive behavior of radiologists during the medical image interpretation process, we propose a context-aware Gaze EstiMation (GEM) network that utilizes eye gaze data collected from radiologists to simulate their visual search behavior patterns throughout the image interpretation process. It consists of a context-awareness module, visual behavior graph construction, and visual behavior matching. Within the context-awareness module, we achieve intricate multimodal registration by establishing connections between medical reports and images. Subsequently, for a more accurate simulation of genuine visual search behavior patterns, we introduce a visual behavior graph structure, capturing such behavior through high-order relationships (edges) between gaze points (nodes). To maintain the authenticity of visual behavior, we devise a visual behavior-matching approach, adjusting the high-order relationships between them by matching the graph constructed from real and estimated gaze points. Extensive experiments on four publicly available datasets demonstrate the superiority of GEM over existing methods and its strong generalizability, which also provides a new direction for the effective utilization of diverse modalities in medical image interpretation and enhances the interpretability of models in the field of medical imaging. https://***/Tiger-SN/GEM. Copyright © 2024, The Authors. All rights reserved.

关键词： Eye movements

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Deep Learning in Palmprint Recognition-A Comprehensive Survey

arXiv

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arXiv 2025年

作者： Gao, Chengrui Yang, Ziyuan Jia, Wei Leng, Lu Zhang, Bob Teoh, Andrew Beng Jin College of Computer Science Sichuan University Chengdu610065 China Singapore School of Computer and Information Hefei University of Technology Hefei China Jiangxi Provincial Key Laboratory of Image Processing and Pattern Recognition Nanchang Hangkong University Nanchang China Pattern Analysis and Machine Intelligence Group Department of Computer and Information Science University of Macau Taipa China School of Electrical and Electronic Engineering College of Engineering Yonsei University Seoul Korea Republic of

Palmprint recognition has emerged as a prominent biometric technology, widely applied in diverse scenarios. Traditional handcrafted methods for palmprint recognition often fall short in representation capability, as they heavily depend on researchers' prior knowledge. Deep learning (DL) has been introduced to address this limitation, leveraging its remarkable successes across various domains. While existing surveys focus narrowly on specific tasks within palmprint recognition-often grounded in traditional methodologies-there remains a significant gap in comprehensive research exploring DL-based approaches across all facets of palmprint recognition. This paper bridges that gap by thoroughly reviewing recent advancements in DL-powered palmprint recognition. The paper systematically examines progress across key tasks, including region-of-interest segmentation, feature extraction, and security/privacy-oriented challenges. Beyond highlighting these advancements, the paper identifies current challenges and uncovers promising opportunities for future research. By consolidating state-of-the-art progress, this review serves as a valuable resource for researchers, enabling them to stay abreast of cutting-edge technologies and drive innovation in palmprint recognition. Copyright © 2025, The Authors. All rights reserved.

关键词： Biometrics

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MKD-YOLO: Multi-Scale and Knowledge-Distilling YOLO for Efficient PPE Compliance Detection

MKD-YOLO: Multi-Scale and Knowledge-Distilling YOLO for Effi...

引用

International Conference on Acoustics, Speech, and Signal Processing (ICASSP)

作者： Juntao Zan Yang Fang Qilie Liu Uswah Khairuddin Yan Li Kaiwei Sun School of Communications and Information Engineering Chongqing University of Posts and Telecommunications Chongqing China Chongqing Key Laboratory of Image Cognition Chongqing University of Posts and Telecommunications Chongqing China Malaysia-Japan International Institute of Technology University of Technology Malaysia Kuala Lumpur Malaysia Department of Electrical and Computer Engineering Inha University Incheon South Korea Key Laboratory of Data Engineering and Visual Computing Chongqing University of Posts and Telecommunications Chongqing China

ISBN: (数字)9798350368741

ISBN: (纸本)9798350368758

YOLO-based models are widely used for personal protective equipment (PPE) compliance detection due to their excellent detection performance and efficiency. However, most YOLO models are not competent for detection tasks in complex industrial scenarios such as remote surveillance and extremely small targets. In addition, there is a lack of effective model lightweighting and knowledge transfer approaches for industrial deployment. To this end, this paper proposes a Multi-scale and Knowledge-Distilling YOLO (MKD-YOLO) based on YOLOv8n for efficient PPE compliance detection. Specifically, in backbone stage, we design an Efficient Multi-Scale Enhanced Convolution (C2f-EMSEC) module and Large Spatial Pyramid Pooling-Fast (LSPPF) module for multi-scale and global-contextual feature learning as well as reducing model complexity. Then, in neck stage, a refined Bidirectional feature Pyramid Network (BPNet) is designated to capture fine-grained details for extremely small object detection. Moreover, we apply channel-wise knowledge distillation to facilitate model lightweighting and domain-specific knowledge transfer learning. Experiments on our proposed dataset and public datasets show that the proposed MKD-YOLO achieves a new state-of-the-art (SOTA) detection performance and efficiency for practical PPE compliance detection tasks. Codes and the dataset are available at https://***/z1Zjt/MKD-YOLO.

关键词： Personal protective equipment YOLO Representation learning Convolution Surveillance Speech enhancement Feature extraction Neck Kernel Knowledge transfer

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Dermoscopic image Classification Using Attention Mechanism and Ensemble Learning Approaches

Dermoscopic Image Classification Using Attention Mechanism a...

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IEEE International Conference on Big Data

作者： Shanchuan Huang Hongwei Lei Liuhan Jin Jinzhu Yang Tao Jiang Yudong Yao Marcin Grzegorzek Chen Li Microscopic Image and Medical Image Analysis Group College of Medicine and Biological Information Engineering Northeastern University China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Shenyang Liaoning China School of Intelligent Medicine Chengdu University of Traditional Chinese Medicine Chengdu China Department of Electrical and Computer Engineering Stevens Institute of Technology USA Institute of Medical Informatics University of Luebeck Luebeck Germany

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