Drug-disease association depicts the accessibility landscape of the association at the molecular level, thereby revealing the intermolecular reaction in the process of drug reposition. However, the scarcity of drug-di...
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In practical applications of deep learning, as the demand for the modeling capability increases, the network size may need to be massively enlarged in response. This may form a significant challenge in practice, espec...
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The objective of image manipulation detection is to identify and locate the manipulated regions in the images. Recent approaches mostly adopt the sophisticated Convolutional Neural Networks (CNNs) to capture the tampe...
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Traditional PCR/NGS-based multigene panel testing is time-consuming and costly. Predicting EGFR mutations directly from H&E stained whole slide images (WSIs) can alleviate these limitations. Furthermore, histopath...
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ISBN:
(数字)9798350386226
ISBN:
(纸本)9798350386233
Traditional PCR/NGS-based multigene panel testing is time-consuming and costly. Predicting EGFR mutations directly from H&E stained whole slide images (WSIs) can alleviate these limitations. Furthermore, histopathological reports contain valuable textual information that correlates with tissue areas in WSIs. However, recent research mainly analyses EGFR mutation status only from a single modality, ignoring rich information contained in reports. In this paper, we propose a report-guided cross-modal representation learning method for predicting EGFR mutations by WSIs. Specifically, we reconstruct report-level embeddings through exploring intrinsic relationships between diagnostic words in histopathological reports and tissue areas in WSIs. Finally, reconstructed histopathological report embedding and aggregated WSI embedding are fused for final prediction. More importantly, molecular testing report is also introduced as prior supervision information at the training stage to guarantee semantic consistency of fused feature and molecular report embedding. We evaluate our method on the TCGA-EGFR public benchmark dataset and an in-house clinical dataset (USTC-EGFR). Experimental results demonstrate that our method outperforms existing approaches in EGFR mutation prediction, highlighting the benefits of cross-modal learning in enhancing feature representational ability. The code is available at https://***/HFUT-miaLab/RCRL.
Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connect...
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Abstracts IgG4-related disease (IgG4-RD) is a multi-organ immune disorder characterized by systemic involvement, diverse pathogenesis, and rarity, which complicates its diagnosis. Traditional medical diagnostic models...
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Semen quality assessment is a very important tool for the timely detection and treatment of infertility disorders. Many artificial intelligence methods for sperm image analysis have emerged in recent years. Sperm dete...
Semen quality assessment is a very important tool for the timely detection and treatment of infertility disorders. Many artificial intelligence methods for sperm image analysis have emerged in recent years. Sperm detection in sperm microscopy is the first step in semen quality assessment. However, the acquisition of sperm electron microscopy images can produce a variety of different background lighting situations. The performance of established methods is susceptible to changes in background illumination. Therefore, a sperm detection method with heterogeneous Laplacian distribution noise background modeling (HLDNBM) is proposed. In this paper the method uses background illumination surface fitting to eliminate the effect of illumination in a single sperm image, and realizes the segmentation of sperm head and sperm tail with different grayscale by upper and lower segmentation threshold surfaces to achieve complete sperm image segmentation and multi-target detection in a single image. This method effectively avoids the degradation of target detection performance caused by sudden changes in illumination in other background modeling methods. Moreover, this method shows strong adaptability for images with different lighting backgrounds, and is friendly to small datasets as well. The experimental results show that the accuracy and sensitivity of the algorithm for sperm detection in images with different grayscale characteristics are very promising, with high universality and robustness.
Realizing Generalized Zero-Shot Learning (GZSL) based on large models is emerging as a prevailing trend. However, most existing methods merely regard large models as black boxes, solely leveraging the features output ...
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ISBN:
(数字)9798331527471
ISBN:
(纸本)9798331527488
Realizing Generalized Zero-Shot Learning (GZSL) based on large models is emerging as a prevailing trend. However, most existing methods merely regard large models as black boxes, solely leveraging the features output by the final layer while disregarding potential performance enhancements from other layers. Indeed, numerous researchers have visually depicted variations in the features learned across different layers of neural networks. Motivated by this observation, we propose a Vision Transformer (ViT)-based GZSL method named Depth-Aware Multi-Modal ViT (DAM2ViT), which exploits multi-level features of ViT. DAM2ViT incorporates a multi-modal interaction block to align semantic information of categories across multiple layers, thereby augmenting the model's capacity to learn associations between visual and semantic spaces. Extensive experiments conducted on three benchmark datasets (i.e., CUB, SUN, AWA2) have showcased that DAM2ViT achieves competitive results compared to state-of-the-art methods.
When deep neural network has been proposed to assist the dentist in designing the location of dental implant, most of them are targeting simple cases where only one missing tooth is available. As a result, literature ...
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Aiming at the accurate and effective coaxiality measurement for twist drill with irregular surface, an optical measurement mechanism is proposed in this paper. First, A high-precision rotation instrument based on four...
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