Membrane proteins are an important kind of proteins embedded in the membranes of cells and play crucial roles in living organisms, such as ion channels,transporters, receptors. Because it is difficult to determinate t...
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Membrane proteins are an important kind of proteins embedded in the membranes of cells and play crucial roles in living organisms, such as ion channels,transporters, receptors. Because it is difficult to determinate the membrane protein's structure by wet-lab experiments,accurate and fast amino acid sequence-based computational methods are highly desired. In this paper, we report an online prediction tool called Mem Brain, whose input is the amino acid sequence. Mem Brain consists of specialized modules for predicting transmembrane helices, residue–residue contacts and relative accessible surface area of a-helical membrane proteins. Mem Brain achieves aprediction accuracy of 97.9% of ATMH, 87.1% of AP,3.2 ± 3.0 of N-score, 3.1 ± 2.8 of C-score. Mem BrainContact obtains 62%/64.1% prediction accuracy on training and independent dataset on top L/5 contact prediction,respectively. And Mem Brain-Rasa achieves Pearson correlation coefficient of 0.733 and its mean absolute error of13.593. These prediction results provide valuable hints for revealing the structure and function of membrane *** Brain web server is free for academic use and available at ***/bioinf/Mem Brain/.
Aiming at the problems of my country's current camellia fruit picking mainly relying on manual picking, large labor and low efficiency, the development and promotion of camellia fruit picking equipment and technol...
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Since the drone input images are usually filmed at very high altitudes and with various viewing angles, cracks appear in many different sizes and shapes. A commonly used crack detection dataset has a small size such a...
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This paper presents a novel computational camera system that has a variable aperture using a thin-film-transistor liquid crystal display. The proposed system can electronically change the geometric shape and color of ...
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This paper presents a method for estimating a seam to fuse two images acquired by asymmetric dual cameras that have different field of views. This method consist of an optimization-based active contour algorithm and m...
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The current diagnostic methods for Autism Spectrum Disorder (ASD) based on Resting-State Functional Magnetic Resonance Imaging (rs-fMRI) face two significant challenges. Firstly, the functional connectivity networks (...
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The auto focusing process is affected by the amount of image content, resulting in the focus curve not meeting the characteristics of the ideal focus curve. In this paper, aiming at the problem that the traditional au...
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Synchronization and pinning control of complex networks is to regulate the agents' behavior and improve network performance. In this article, we review some recent developments in pinning control. Stability algori...
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The aim of this study is to assess the functional connectivity from resting state functional magnetic resonance imaging (fMRI) data. Spectral clustering algorithm was applied to the realistic and real fMRI data acquir...
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ISBN:
(纸本)9781424466238
The aim of this study is to assess the functional connectivity from resting state functional magnetic resonance imaging (fMRI) data. Spectral clustering algorithm was applied to the realistic and real fMRI data acquired from a resting healthy subject to find functionally connected brain regions. In order to make computation of the spectral decompositions of the entire brain volume feasible, the similarity matrix has been sparsified with the t-nearestneighbor approach. Realistic data were created to investigate the performance of the proposed algorithm and comparing it to the recently proposed spectral clustering algorithm with the Nystrom approximation and also with some well-known algorithms such as the Cross Correlation Analysis (CCA) and the spatial Independent Component Analysis (sICA). To enhance the performance of the methods, a variety of data pre and post processing steps, including data normalization, outlier removal, dimensionality reduction by using wavelet coefficients, estimation of number of clusters and optimal number of independent components (ICs). Results demonstrate the applicability of the proposed algorithm for functional connectivity analysis.
In this paper, a rectangular microwave filter with rectangular groove is designed. The filter adopts symmetrical three-stage structure. The first section is the slot line waveguide section to realize the input / outpu...
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