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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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A multi-start procedure for the minimum latency problem

A multi-start procedure for the minimum latency problem

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7th IFAC Conference on Manufacturing Modelling, Management, and Control, MIM 2013

作者： Angel-Bello, Francisco Alvarez, Ada García, Irma Tecnológico de Monterrey Campus Monterrey Department of Industrial and Systems Engineering Ave. Eugenio Garza Sada 2501 Monterrey Nuevo León CP 64849 Mexico Universidad Autónoma de Nuevo León Graduate Program in Systems Engineering Ave. Universidad s/n San Nicolás Nuevo León CP 66451 Mexico Universidad Autónoma de Coahuila Research Center on Applied Mathematics Edif. S Campo Redondo Saltillo Coahuila CP 25280 Mexico

ISBN: (纸本)9783902823359

In this paper we address a minimum latency problem and propose a multi-start strategy for solving it. For constructing initial solutions two procedures are designed, which are based on metaheuristic GRASP. We also develop a post-processing procedure based on Path Relinking to improve the obtained solutions. We carry up an extensive experimentation with 225 symmetrical instances to evaluate our procedures. In addition, using instances from literature, we compare our best procedure with previously reported methods, showing that the proposed procedure outperforms them in terms of solution quality and in elapsed CPU time to reach the solution. © IFAC.

关键词： Supply chains

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A Multi-Start Procedure for the Minimum Latency Problem

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IFAC Proceedings Volumes 2013年第9期46卷 436-441页

作者： Francisco Angel-Bello Ada Alvarez Irma García Tecnológico de Monterrey Campus Monterrey Department of Industrial and Systems Engineering Ave. Eugenio Garza Sada 2501. Monterrey Nuevo León México CP 64849 Universidad Autónoma de Nuevo León Graduate Program in Systems Engineering Ave. Universidad s/n. San Nicolás Nuevo León México CP 66451 Universidad Autónoma de Coahuila Research Center on Applied Mathematics Edif. S Campo Redondo Saltillo Coahuila México CP 25280

关键词： Operational research Supply chains networks

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Abstracts for the 6th Congress of Asian Sleep research Society

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Sleep and Biological Rhythms 2009年第4期7卷 A1-A49页

作者： Seog Ju Kim In Kyoon Lyoo Yu-Jin Lee Do-Un Jeong Hirohiko Kanai Masanori Ookubo Atsushi Yoshimura Masako Okawa Noto Yamada Takeshi Munezawa Yoshitaka Kaneita Yoneatsu Osaki Hideyuki Kanda Tadahiro Ohtsu Masumi Minowa Kenji Suzuki Susumu Hijuchi Hiroyuki Suzuki Takashi Ohida Takashi Abe Yoko Komada Shoichi Asaoka Yuichi Inoue Jin-Seong Lee Sang-Yong Cho Deependra Kumar Hruda N. Mallick Velayudhan M. Kumar Mahesh K. Kaushik Akihiro Karashima Noiihiro Katayama Mitsuyuki Nakao Ravindra P. Nagendra Sathiamma Sulekha Sathyaprabha T. Narasappa Pradhan Nityanadan Bindu M. Kutty M. Nirmala P. N. Ravindra Basavaraj Ramappa Tubaki T. N. Sathyaprabha D. Sudhakar G. S. Lavekar C. R. Chandrashekar Kazuyoshi Kitaoka Mika Shimizu Sachiko Chikahisa Kazuo Yoshizaki Hiroyoshi Sei Jong-Won Kim Misa Takegami Shin Yamazaki Yasuaki Hayashino Rei Ono Koji Otani Miho Sekiguchi Shinichi Konno Shunichi Fukuhara Antonia J. Jakobson Paul Fitzgerald Russell Conduit Xin Shirley Li Siu Ping Joyce Lam Wai Man Mandy Yu Yun Kwok Wing Kazue Okamoto-Mizuno Koh Mizuno Mituaki Yamamoto Shuichiro Shirakawa Hirokazu Doi Mikako Kato Kazuyuki Shinohara Masako Tamaki Shiori Matsuda Katsuo Yamazaki Tadao Hori Keiko Ogawa Kazumi Takahashi Kunio Kitahama Katuo Yamazaki Yoshimasa Koyama Kohei Shioda Yugo Ueda Yukiko Nakamura Clara Inoue Kazushige Goto Sunao Uchida Yuko Morita Yoshiko Honda Tohru Kodama Mari Hagihara Toru Nakajima Masato Saito Yoshihiko Koga Shinichiro Tanaka Hiroshi Yamadera Madoka Takahara Sachiko Suwa Minoru Onozuka Sadao Sato Fumiharu Togo Taiki Komatsu Takeshi Mitani Jongbae Choi Bin Zhang Taeko Sasai Hiromi Mitsubayashi Mitsuhiro Ohtsu Isao Hasegawa Tatsuya Ishii Akira Komori Asami Suzuki Yue Nakahara Mitsuyasu Hiroki Mariko Nakauma Nobuo Someya Tomomasa Ochiai Shouhei Komori Rayleigh Ping-Ying Chiang Zai-Ting Yeh Seong T. Kim Seung H. Yoon Jeong S. Kwon Jong H. Choi Hyung J. Ahn Youngsoo Kim Bolortuya Yunren Lichao Chen Radhika Basheer Robert W. Mccarley Robert E. Strecker Makoto Honda Tetsuaki Arai Miyuki Fukazawa Yutaka Honda Kuniaki T Department of Psychiatry Gachon University of Medicine and Science Incheon Republic of Korea Department of Psychiatry Seoul National University Seoul Republic of Korea Department of Neuropsychiatry and Center for Sleep and Chronobiology Seoul National University Hospital Seoul Republic of Korea Department of Neuropsychiatry Seoul National University Hospital Seoul Republic of Korea Seoul National University Hospital Seoul Republic of Korea Department of Psychiatry Shiga University of Medical Science Otsu Japan Division of Public Health Department of Social Medicine Nihon University School of Medicine Tokyo Japan Department of Public Health Nihon University School of Medicine Tokyo Japan Division of Environmental and Preventive Medicine Department of Social Medicine Faculty of Medicine Tottori University Yonago Japan Department of Hygiene and Preventive Medicine Fukushima Medical University Fukushima Japan Department of Public Health Showa University School of Medicine Tokyo Japan Faculty of Humanities Seitoku University Matsudo Japan Section on Behavioral Science Division of Clinical Research National Hospital Organization Kurihama Alcoholism Center Yokosuka Japan Department of Otolaryngology Second Hospital Fujita Health University Nagoya Japan National Hospital Organization Kurihama Alcoholism Center Kanagawa Japan Metropolitan Police Department Criminal Investigation Laboratory Tokyo Japan Japan Somnology Center Neuropsychiatrie Research Institute Tokyo Japan Department of Somnology Tokyo Medical University Tokyo Japan Japan Somnology Center Neuropsychiatric Research Institute Tokyo Japan Department of Somnology Tokyo Medical and Dental University Tokyo Japan Center for Sleep and Chronobiology Department of Psychiatry and Behavioral Science Seoul National University College of Medicine Seoul Republic of Korea Department of Psychiatry and Behavioral Science Center for Sleep and Chronobiology Seoul Republic of Korea Department of Physiology Al

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Effects of Adaptive Cruise Control and Alert Modality on Driver Performance

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Transportation research Record 2006年第1期1980卷 49 - 56页

作者： John D. Lee Daniel V. McGehee Timothy L. Brown Dawn Marshall Cognitive Systems Laboratory Department of Mechanical and Industrial Engineering 2130 Seamans Center Human Factors and Vehicle Safety Research Program Public Policy Center 227 South Quad Human Factors Laboratory National Advanced Driving Simulator and Simulation Center University of Iowa 2401 Oakdale Boulevard Iowa City IA 52242.

Adaptive cruise control (ACC) is a rapidly emerging in-vehicle technology that can enhance or degrade driving safety. A critical factor governing the safety benefit of ACC concerns the driver's ability to assume control of the vehicle in situations that exceed ACC capabilities. The effectiveness of various warning modalities for reengaging distracted drivers during severe braking situations that exceed ACC capability was examined. Warnings that paired a visual icon with sound, seat vibration, or brake pulsation or that combined all three cues were compared. A total of 60 participants drove for 35 min in the National Advanced Driving Simulator. Drivers experienced two severe, four moderate, and eight mild braking situations. ACC could accommodate all but the two severe situations without driver intervention. It also provided a substantial benefit during mild events of lead vehicle braking, enabling drivers to maintain a longer, more consistent minimum time to collision. Unlike performance in previous studies, ACC did not decrease safety during severe braking situations. The combination of a visual icon with sound, seat vibration, or brake pulsation led to slower brake reaction time in severe braking situations, but the grouping of all four warning strategies led to a similar minimum time to collision and maximum braking. In contrast to several previous studies, these results suggest that drivers can effectively assume control when warned that ACC braking authority has been exceeded. Additional research is needed to identify the boundary conditions that specify when drivers can successfully intervene and retake control and whether a multimodal combination of cues can be crafted to speed rather than slow driver response.

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Fast sum of absolute differences visual landmark detector

Fast sum of absolute differences visual landmark detector

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IEEE International Conference on Robotics and Automation (ICRA)

作者： C. Watman D. Austin N. Barnes G. Overett S. Thompson Robotic Systems Laboratory Department of Systems Engineering RSISE Australian National University Canberra ACT Australia Autonomous Systems and Sensing Technologies Program NICTA Canberra ACT Australia Digital Human Research Center National Institute for Advanced Industrial Science and Technology Koto Japan

This paper presents various optimisation that can be applied to the sum of absolute differences (SAD) correlation algorithm for automated landmark detection. This has applications in mobile robotic navigation and mapping. We show how some assumptions about the environment and the generic form of strong landmarks selected by the SAD correlation algorithm have led to the development of an algorithm to enable near real tune selection of strong landmarks from visual information. The landmarks that have been selected from a series of frames using our optimisation are shown to be stable through the image sequence, demonstration the scale invariance of the landmarks that are selected by the SAD correlation algorithm.

关键词： Navigation Robot sensing systems Mobile robots Detectors Service robots Robot vision systems Indoor environments Feature extraction Pixel Laboratories

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A Moment-Based Method for Large-Scale Generalized Eigenvalue Problems

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Applied Numerical Analysis & Computational Mathematics 2004年第2期1卷

作者： Tetsuya Sakurai Hiroto Tadano Yuichi Inadomi Umpei Nagashima Department of Computer Science University of Tsukuba Tsukuba 305-8573 Japan Core Research for Evolutional Science and Technology Japan (CREST) Doctoral Program of Systems and Information Engineering University of Tsukuba Tsukuba 305-8573 Japan Grid Technology Research Center National Institute of Advanced Industrial Science and Technology Tsukuba 305-8568 Japan

In this paper we consider a method for finding several eigenvalues and corresponding eigenvectors of large-scale generalized eigenvalue problems. In this method, a small matrix pencil that has only the desired eigenvalues is derived using complex moments obtained via numerical integration. Since the process to derive the moments can be performed in parallel and we do not need to exchange data between processes, the presented method is suitable for master-worker programming models. We have implemented and tested the proposed method in a grid RPC (remote procedure call) system. Numerical examples illustrate the properties of our approach. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

关键词： Eigenvalue problems moment-based method parallel algorithm

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Monitoring the navy's strategic reserve of ozone-depleting substances

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NAVAL ENGINEERS JOURNAL 2002年第4期114卷 95-104页

作者： Smith, DE Breslin, DA Toms, GS Norton, P DENNIS E. SMITH PH.D. is currently a statistical consultant for GEO-CENTERS INC. He received a B.A. in Mathematics (magna cum laude)from Wabash College and an M.S. in mathematics an M.S. in statistics and a Ph.D. in statistics from the University of Wisconsin. From November 1973 until February 1999 he was president and principal statistician at Desmatics Inc. where he participated in a number of studies involving the application of statistical methods to various technical problems in the Navy's environmental-protection and auxiliary-machinery programs. Dr. Smith was instrumental in developing the statistical procedures underlying the Navy's ODS reserve monitoring plan. DAVID A. BRESLIN P.E. is the director of technical operations for the Naval Surface Warfare Center and chairs the ASNE/SNAME Joint Committee on Environmental Engineering. He received a master of science in aerospace engineering from Virginia Tech a master of engineering administration in industrial and systems engineering from Virginia Tech and a bachelor of engineering in mechanical engineering from Stevens Institute of Technology. From 1993 to 1997 he was the program manager of the Naval Sea Systems Command's CFC and Halon Elimination Program and played a critical role in establishing the Navy's strategic reserve of ozone-depleting substances. Because of his many efforts he received a Stratospheric Ozone Protection Award in 1995 from the U.S. Environmental Protection Agency in recognition of “exceptional contributions to global environmental protection”. GREGORY S. TOMS P.E. is the CFC &Halon Elimination Program Manager for the Naval Sea Systems Command (NAVSEA). He received a master of science degree in mechanical engineering from the University of Maryland and a B.S. degree in mechanical engineering from West Virginia University. From 1984 to 1997 he was employed at the Naval Surface Warfare Center Carderock Division Annapolis Detachment (formerly David Taylor Research Center)where he worked on the development of advanced cent

The domestic production of the most powerful ozone-depleting substances (ODSs) has permanently ceased and the abundant supplies of a number of refrigerants, fire-fighting agents, and solvents, once taken for granted, are now a thing of the past. The Navy has adopted a successful strategy for addressing the threat posed by the unavailability of ODSs. That strategy includes relying on a strategic reserve of ODSs. Considering that the strategic reserve will play a critical role in sustained Fleet operations into the middle of the century, it is important to record the history of the reserve and to document lessons learned in order to educate future generations that may face similar challenges. This is the third of three papers that cover all aspects of the Navy's strategic reserve of ODSs. Breslin (1999) documented the history of the Navy's effort to size, establish, and monitor a reserve designed to support Fleet operations until the middle of the century. Breslin, Smith, and Toms (2000) addressed in detail the process used to estimate the required size of the reserve, including the survey method, statistical analyses, and sizing algorithms. This paper discusses the Navy's plan for monitoring the Navy's strategic reserves of ODSs and describes the methods used in the monitoring process. In particular it discusses the underlying assumptions and statistical techniques associated with the Navy's prediction of the expected drawdown of the reserves. A comparison of actual data, collected since the strategic reserves began operations in 1995, with the predicted reserve drawdown, is included in the paper.

关键词： Marine engineering

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Survey of reduced workload and crewing strategies for ocean patrol vessels

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NAVAL ENGINEERS JOURNAL 2001年第2期113卷 29-44页

作者： Baker, C Krull, R Snyder, G Lincoln, W Malone, TB Clifford C. Baker CIE CHFEP is a senior staff scientist at Carlow International Incorporated. He has applied most of his 24 years of experience in the application of human engineering technology to maritime systems. Mr. Baker has directed much of Carlow's efforts to reduce ship workload and to improve human performance and maritime safety through application of human factors methods and data. He is a Certified Industrial Ergonomist (CIE) as well as a Certified Human Factors Engineering Professional (CHFEP). Both certifications were granted by Oxford Research where Mr. Baker also serves as an Advisory Board member. Russell D. Krull P.E. is a senior engineer with A&T/Proteus Engineering with more than 18 years of experi-ence in marine engineering naval architecture and program management including 16 years of active duty in the U.S. Coast Guard. Recent experience includes advanced ship design studies engineering software development technical support for the USMC Advanced Amphibious Assault Vehicle propulsion systems analyses ship structural engineering and cargo handling systems engineering. Mr. Krull has an M.S.E. in naval architecture and marine engineering and an M.S.E. in industrial and operations engineering from University of Michigan and a B.S. in ocean engineering from the U.S. Coast Guard Academy. Capt. Glenn L. Snyder USCG. Regrettably since this paper was originally written Capt. Snyder has passed away. At the time of his death he was an operations specialist assigned to the Coast Guard's Deepwater Capabilities Replacement Project as Chief of Human Systems Integration. He served as commanding officer of the patrol boat Cape George (WPB-95306) the icebreaking tug Biscayne Bay (WTGB-104) and the cutter Legare (WMEC-911). A 1975 graduate of the U.S. Coast Guard Academy Capt. Snyder held an M.A. in national security and strategic studies from the U.S. Naval War College and an M.A. in international relations from Salve Regina College. In addition he was a 1998 fellow of the Foreign Service

The U.S. Coast Guard is in the concept exploration phase of its Integrated Deepwater System (IDS) acquisition project. This project will define the next generation of surface, air and command, control, communications, computers, intelligence, surveillance, and reconnaissance (C4ISR) assets used to perform the Coast Guard's missions in the IDS environment (>50 NM off the U. S. coastline). As part of early technology investigations, the needs exist to: (1) analyze the workload requirements of the IDS, (2) identify alternative means to perform ship's work, and (3) optimize ship manning consistent with ship workload, performance criteria, and the available tools and equipment aboard. To reduce shipboard work requires an understanding of the mission and support requirements placed on the vessel and crew, how these requirements are currently met, and how requirements might otherwise be met to reduce workload and crew size. This study examined currently implemented workload and manpower reducing approaches of commercial maritime fleets, U.S. and foreign navies, and foreign coastguards. These approaches were analyzed according to evaluation criteria approved by the IDS acquisition project team. From this, strategies for shipboard work reduction that may be considered for adoption by the IDS were identified and analyzed according to performance and costs factors. Ten workload-reducing strategies were identified: damage control, bridge, multiple crewing, engineering, risk acceptance, modularity, deck, enabling technologies, ship/personnel readiness, and operability and maintainability.

关键词： Naval vessels

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Navy's CFC & Halon elimination program

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NAVAL ENGINEERS JOURNAL 2000年第1期112卷 91-112页

作者： Toms, GS Breslin, DA Brunner, GP Thill, JC Gregory S. Toms RE:is the CFC & Halon Elimination Program Manager for the Naval Sea Systems Command (NAVSEA). He received a master of science degree in mechanical engineering from the University of Maryland and a B.S. degree in mechanical engineering from West Virginia University. From 1984 to 1997 he was employed at the Naval Surface Warfare Center Carderock Division Annapolis Detachment (formerly David Taylor Research Center) where he worked on the development of advanced centrifugal compressor air conditioning plants for shipboard applications. He received the Stratospheric Ozone Protection Award in 1998 from the U.S. Environmental Protection Agency in recognition of his exceptional leadership and technical achievements in eliminating ozone-depleting substances from Navy ships. He is licensed as a registered Professional Engineer in the state of Texas. David A. Breslin P.E.:is the Director of Technical Operations for the Naval Surface Warfare Center and is the Chairperson of the ASNE Committee on Environmental Engineering. He received a master of science in aerospace engineering from Virginia Tech in 1991 a master of engineering administration in industrial & systems engineering from Virginia Tech in 1991 and a bachelor of engineering in mechanical engineering from Stevens Institute of Technology in 1985. From 1993 to 1997 he was the program manager of the Naval Sea Systems Command's CFC & Halon Elimination Program. Because of his many efforts he received a Stratospheric Ozone Protection Award in 1995 from the U.S. Environmental Protection Agency in recognition of “exceptional contributions to global environmental protection”. Gregory P. Brunner:was employed by the Carderock Division of the Naval Surface Warfare Center and Naval Sea Systems Command (NAVSEA) from 1983 until 1997. From 1993 to 1997 he served as the R&D program manager for the NAVSEA CFC & Halon Elimination Program Office. Program efforts resulted in the development of new refrigerants for backfit into existing shipboard air-conditioning

The domestic production of the most powerful Ozone-Depleting Substances (ODSs) has permanently ceased and the abundant supplies of a number of inexpensive refrigerants, fire-fighting agents, and solvents, once taken for granted, are now a thing of the past. The Navy's original strategy of conserving ODSs, converting systems and processes where feasible, relying on strategic reserves where necessary, and developing "ozone-friendly" equip ment for new-design surface ships and submarines is succeeding. The purpose of this paper is to document the Navy's efforts to date relative to combating the threat to uninterrupted Fleet operations posed by the cessation of ODS production. Specifically, this paper addresses the Navy's shipboard conversion programs for air-conditioning and refrigeration (AC&R) systems, the development of next-generation AC&R systems, the selection of halon substitutes for new-construction fire-fighting systems, and the Navy's alternative to CFC-113 in the cleaning of critical oxygen systems.

关键词： conversion program Ozone depleting substances trichlorotrifluoroethane GRANTS fire fighting strategic reserves Solvents oxygen systems Submarine Halons

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