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Human osteoblast and fibroblast behavior on modified zirconia implant surfaces

Clinical Oral Implants Research 2018年第S17期29卷 190-190页

作者： Mariana Cruz Joana Marques Gabriella Peñarrieta-Juanito Filipe Silva António Mata Mafalda Costa Georgina Miranda Júlio Souza Ricardo Magini Silvio Mario Meloni João Caramês Faculty of Dental Medicine Universidade de Lisboa Portugal Oral Biology and Biochemistry Research Group LIBPhys Faculty of Dental Medicine University of Lisbon Portugal Center for Research on Dental Implants Post-graduate program in dentistry (PPGO) School of Dentistry Federal University of Santa Catarina (UFSC) Brazil Center for Microelectromechanical Systems (CMEMS) Dept. of Mechanical Engineering University of Minho Portugal Center for Research on Dental Implants Post-graduate program in dentistry (PPGO) School of Dentistry Federal University of Santa Catarina (UFSC) Portugal NA Italy Faculty of Dental Medicine University of Lisbon Portugal

Background: Zirconia dental implants have been proposed as an option for oral rehabilitation. Hydroxyapatite and calcium phosphate based coatings have been described to improve the bioactivity of zirconia, however, there is a need for alternate solutions since these coatings may delaminate. Aim/Hypothesis: The aim of this study was to compare the in vitro response of human fetal osteoblasts and human gingival fibroblasts in contact with Zirconia based implant surfaces‐ Zirconia (control), Zirconia containing hydroxyapatite (ZrHA) or beta tricalcium phosphate (ZrTCP). Material and Methods: Zirconia discs (control, 5% HA or 5% TCP) were produced by a novel pressing‐sintering technique under appropriate and similar conditions to achieve controlled surfaces. Human osteoblasts and gingival fibroblasts were cultured for 15 days by previously described methods. Morphology and cellular adhesion were observed using scanning electron microscopy (SEM) after 1 and 7 days. Cell viability and proliferation were evaluated at pre‐defined time‐points (1, 3, 7 and 14 days) using a commercial resazurin‐based method. Alkaline phosphatase (ALP) activity of human osteoblasts was evaluated at 7 and 14 days. All results were presented as mean fluorescence intensity (AU) ± standard deviation (SD). Group comparisons were tested using Anova (Tukey's post‐hoc) using appropriate statistical software and significance was set _I_P_i_ < 0.05. Results: SEM presented a good cell spreading in all groups on osteoblasts and fibroblasts. Cell viability and proliferation increased over time for all groups on the two types of cells, with osteoblasts viability being significantly higher on ZrHA group (211.32 ± 39.04 AUs) comparing to Zr (90.82 ± 29.95 AUs) and Zr‐TCP (125.51 ± 36.92 AUs) at 14 days of culture. However, when assessing fibroblast viability, the Zr group (249.98 ± 60.40 AUs, 595.98 ± 69.40 AUs) presented significantly higher values when compared to the remaining groups at 7 and 14 day culture

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Biological responses of fibroblasts and osteoblasts on modified bioactive titanium implant surfaces

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Clinical Oral Implants Research 2018年第S17期29卷 191-191页

作者： Beatriz Ferreira Mariana Cruz Gabriella Peñarrieta-Juanito Joana Marques Filipe Silva João Caramês Júlio Souza Ricardo Magini Mafalda Costa Georgina Miranda António Mata Faculty of Dental Medicine Universidade de Lisboa Portugal Center for Research on Dental Implants Post-graduate program in dentistry (PPGO) School of Dentistry Federal University of Santa Catarina (UFSC) Brazil Oral Biology and Biochemistry Research Group LIBPhys Faculty of Dental Medicine University of Lisbon Portugal Center for Microelectromechanical Systems (CMEMS) Dept. of Mechanical Engineering University of Minho Portugal Bone Physiology Research Group LIBPhys Faculty of Dental Medicine University of Lisbon Portugal Center for Research on Dental Implants Post-graduate program in dentistry (PPGO) School of Dentistry Federal University of Santa Catarina (UFSC) Portugal

Background: Calcium‐phosphate bioactive coatings have been suggested to improve the biological response of titanium. We have developed a new manufacturing protocol that enables integration of these bioactive materials in a titanium scaffold, overcoming the mechanical limitations of coatings. However, the biological behavior of these new materials is not yet described. Aim/Hypothesis: The aim of this study was to evaluate the behavior of human fetal osteoblasts and human gingival fibroblasts in contact with Titanium (Ti), Ti with 5% hydroxyapatite (TiHA) or Ti with 5% beta tricalcium phosphate (Ti‐TCP). Material and Methods: Ti, TiHA and Ti‐TCP discs were produced with homogeneous surface roughness. Human fetal osteoblasts and human gingival fibroblasts were cultured on discs for 14 days using previously established methods. Morphology and cellular adhesion were analyzed using scanning electron microscopy (SEM) after 1 and 7 days. Cell viability and proliferation were evaluated at pre‐defined time‐points (1, 3, 7 and 14 days) using a commercial resazurin‐based method. Alkaline phosphatase (ALP) activity was evaluated at 7 and 14 days for osteoblasts. All results were presented as mean fluorescence intensity (AU) ± standard deviation (SD). Mineralization patterns were evaluated using hydroxyapatite fluorescence staining. Group comparisons were tested using Anova (Tukey's post‐hoc) using appropriate statistical software and significance was set _I_P_i_ < 0.05. Results: The results showed similar cells adhesion on all materials. Osteoblast viability was higher on Ti‐TCP (114.47 ± 15.56 AU) when comparing to TiHA (54.11 ± 4.05 AU) and Titanium (41.52 ± 2.86 AU) group at 14 days of culture (_I_P_i_ < 0.05). However, cell proliferation was not statistically different between study groups. A higher fibroblast viability and proliferation on Ti specimens was observed compared to other groups, although without statistically significant. A significant higher ALP activity was ob

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On dynamic analysis and control of an elevator system using polynomial chaos and Karhunen-Loève approaches

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Procedia engineering 2017年 199卷 1629-1634页

作者： Diego Colón Americo Cunha Stefan Kaczmarczyk José M. Balthazar University of São Paulo - USP Escola Politécnica da USP Laboratório de Automação e Controle (LAC -PTC) Brazil Rio de Janeito State University - UERJ NUMERICO - Nucleus of Modeling and Experimentation with Computers Brazil The University of Northampton Faculty of Arts Science and Technology UK Technological Institute of Aeronautics - ITA Graduate Program in Aeronautics and Mechanical Engineering Brazil

The paper deals with the quantification of uncertainties in an elevator system, subjected to lateral vibration induced by the car guide rail irregularities, with and without a feedback control system. A mathematical model for the elevator system is derived, and a stochastic model for the rail profile irregularities is constructed. This model of uncertainties describes the rail profile as a random field, which is represented by means of Karhunen-Loève expansion. Polynomial chaos is employed to compute the propagation of uncertainties through the stochastic model, in order to evaluate the disturbance rejection properties and robustness of the closed-loop system.

关键词： elevator systems nonlinear dynamics uncertainty quantification polynomial chaos

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Planning of Modular Fixtures in a Robotic Assembly System

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Procedia CIRP 2016年 41卷 252-257页

作者： Hossein Tohidi Tarek AlGeddawy Graduate Student in Engineering Management Program University of Minnesota Duluth Duluth Minnesota USA Assistant Professor Mechanical and Industrial Enigneering Department Univerisity of Minnesota Duluth Duluth Minnesota USA

Increasing product varieties is beneficial for companies in terms of expanding the market and harmful in terms of increasing manufacturing costs. Designing and fabricating different fixtures for producing different products with different geometries is a significant portion of the manufacturing costs. To overcome to this problem in a mid-volume mid-variety robotic assembly system, an optimization model is developed to minimize hole-pattern modular fixtures’ preparation time and efforts. Using this model, the best locations for placing different products and jigging-pins are determined, considering all possible part's translations and rotations on the holder. The model is solved by GAMS using the BARON solver for different examples to prove the efficacy of the proposed model.

关键词： Modular fixtures Mathematical programing Optimization Rotation Translation Nonlinear model

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Experimental Investigation on Liquid Film Asymmetry in Air-Water Horizontal Annular Flow

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AIP Conference Proceedings 2016年第1期1737卷 1-7页

作者： Setyawan, Andriyanto andriyanto@polban.ac.id Deendarlianto deendarlianto@ugm.ac.id Indarto indarto@ugm.ac.id Fredrick Neo fredrick.neo1991@*** Graduate Program Department of Mechanical and Industrial Engineering Faculty of Engineering Gadjah Mada University Jalan Grafika No. 2 Yogyakarta 55281 Indonesia Department of Refrigeration and Air Conditioning Engineering Politeknik Negeri Bandung Bandung 40123 Indonesia Department of Mechanical and Industrial Engineering Faculty of Engineering Gadjah Mada University Jalan Grafika No. 2 Yogyakarta 55281 Indonesia

The asymmetry of circumferential liquid film thickness distribution in an air-water horizontal annular flow has been experimentally investigated using superficial gas and liquid velocity of 10 - 40 m/s and 0.025 to 0.4 m/s, respectively. In general, the film at the bottom of the pipe will be thicker than that of the side and the top. The asymmetry parameter could be expressed in the ratio of average film thickness to the bottom film thickness or the ratio of the top-tobottom film thickness. Measurement using compact multiple probe instrument shows that the circumferential film thickness distribution is strongly affected by superficial gas velocity. The higher gas velocity results in the more uniform liquid film circumferential distribution. In comparison to the existing correlations, the asymmetry parameter resulted from the experiment shows a good agreement. It is also shown from the experiment that a less symmetry of film thickness distribution is resulted when the gravity force is dominant. A more symmetry distribution is resulted when the inertial force takes control. [ABSTRACT FROM AUTHOR]

关键词： Air-water interfaces Annular flow (Fluid dynamics) Liquid films Thickness measurement Asymmetry (Chemistry) Advection

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Dark Excitons: Dark-Exciton-Mediated Fano Resonance from a Single Gold Nanostructure on Monolayer WS2at Room Temperature (Small 31/2019)

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Small 2019年第31期15卷 1970164-1970164页

作者： Mingsong Wang Zilong Wu Alex Krasnok Tianyi Zhang Mingzu Liu He Liu Leonardo Scarabelli Jie Fang Luis M. Liz-Marzán Mauricio Terrones Andrea Alù Yuebing Zheng Department of Mechanical Engineering Texas Materials Institute The University of Texas at Austin Austin TX 78712 USA Photonics Initiative Advanced Science Research Center Physics Program Graduate Center Department of Electrical Engineering City College of the City University of New York New York NY 10031 USA Department of Materials Science and Engineering Department of Physics Department of Chemistry Center for 2-Dimensional and Layered Materials The Pennsylvania State University University Park PA 16802 USA Department of Chemistry and Biochemistry California NanoSystems Institute University of California Los Angeles Los Angeles CA 90095 USA Bionanoplasmonics Laboratory CIC biomaGUNE Paseo de Miramón 182 20014 Donostia-San Sebastián Spain Ikerbasque Basque Foundation for Science 48013 Bilbao Spain Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine CIBER-BBN 20014 Donostia-San Sebastián Spain

In article number 1900982, Yuebing Zheng and co‐workers demonstrate that the coupling between out‐of‐plane localized surface plasmon resonances and dark K‐K excitons in monolayer WS2 leads to narrow Fano resonance... 详细信息

关键词： 2D transition metal dichalcogenides dark excitons Fano resonance gold nanoparticles plasmonics

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High accuracy springback simulation by using material model considering the SD effect

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Journal of Physics: Conference Series 2018年第1期1063卷

作者： Nobuyasu Noma Koji Hashimoto Taiki Maeda Toshihiko Kuwabara Advanced Engineering Development Centre UNIPRES CORPOLATION 3-19-1 Shin-Yokohama Kohoku-ku Yokohama-shi Kanagawa 222-0033 Japan Department of Industrial Technology and Innovation Graduate School of Engineering Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei-shi Tokyo 184-8588 Japan Division of Advanced Mechanical Systems Engineering Institute of Engineering Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei-shi Tokyo 184-8588 Japan

In order to enhance the accuracy of springback simulation, the strength differential (SD) effect, i.e., the difference in flow stress between tension and compression, of a high strength cold-rolled steel sheet with a tensile strength of 980 MPa is measured by means of in-plane tension-compression test apparatus. Bi-axial stress tests are also performed to measure the contour of plastic work of the test material. From those experimental results, the material model which can consider the SD effect is determined. Furthermore, this material model is implemented into commercial FEM code by using user-subroutine function. To check the validity of this model and established FEM analysis system, curvature-hat crush forming experiment is performed. By comparing the experimental result and forming simulation result, the accuracy of the material model which can consider the SD effect is validated. Consequently it is concluded that the use of material model which is capable of reproducing the SD effect is a must to enhance the accuracy of springback simulation.

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Crystallization of calcium carbonate (CaCO3) in a flowing system: influence of Cu2+ additives on induction time and crystalline phase transformation

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AIP Conference Proceedings 2016年第1期1725卷 020093-1-020093-7页

作者： Usmany, Y. usmany.yohana@*** Putranto, W. A. Bayuseno, A. P. Muryanto, S. stefanusmuryanto@yahoo.com.au Mechanical Engineering Graduate Program Diponegoro University Tembalang Campus Semarang 50275 Indonesia Department of Chemical Engineering UNTAG University in Semarang BendhanDhuwur Campus Semarang 50233 Indonesia

Scaling of calcium carbonate (CaCO3) is commonly found in piping systems in oil, gas, desalination and other chemical processes. The scale may create technical problems, leading to the reduction of heat transfer, increase of energy consumption and unscheduled equipment shutdown. This paper presents crystallization scaling experiments and evaluation of the effect of Cu2+ additives on the induction time and calcium carbonate transformation. The crystals precursors were prepared using equimolar of CaCl2 and Na2CO3 resulted in concentrations of 3000 ppm Ca2+ in the solution. The Cu2+ in amounts of 0, 1 and 10 ppm was separately added in the solution. The flow rates (20, 35, and 60 mL/min) and elevated temperatures (27, 35 and 45°C) were selected in the study. The induction time for crystallization of CaCO3 was observed by measuring the solution conductivity over time, while the phase transformation of calcium carbonate was examined by XRD method and SEM/EDX. It was found that the conductivity remained steady for a certain period reflecting to the induction time of crystal formation, and then decreased sharply afterwards,. The induction time was increased from 34 and 48 minutes in the presence of Cu additives (1 and 10 ppm), depending on the flow rates and temperature observed. In all the experiments, the Cu2+ addition leads to the reduction of mass of crystals. Apparently, the presence of Cu2+ could inhibit the CaCO3 crystallization. In the absence of Cu2+ and at elevated temperature, the crystals obtained were a mixture of vaterite and calcite. In the presence of Cu2+ and at elevated temperature, the crystals formed were aragonite and calcite. Here, the presence of Cu2+ additives might have controlled the crystal transformation of CaCO3. [ABSTRACT FROM AUTHOR]

关键词： Crystallization Calcium carbonate Copper ions Additives Crystalline interfaces

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Multiobjective cross entropy for electromagnetic optimization

Multiobjective cross entropy for electromagnetic optimizatio...

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IEEE Conference on Electromagnetic Field Computation

作者： Teodora Cardoso Bora Viviana Cocco Mariani Leandro dos Santos Coelho Piergiorgio Alotto Department of Electrical Engineering Federal University of Parana Curitiba PR Brazil Pontifical Catholic University of Parna (PUCPR) Mechanical Engineering Graduate-Program (PPGEM) Curitiba PR Brazil Pontifical Catholic University of Parana (PUCPR) Industrial and Systems Engineering Graduate Program (PPGEPS) Curitiba PR Brazil Dipartimento di Ingegneria Industriale Università di Padova Padua Italy

ISBN: (纸本)9781509010332

The Cross-Entropy (CE) method has been designed to solve rare event simulation problems and later extended to single-objective optimization problems. In this paper, we propose a novel CE approach for multi-objective optimization and applied it to the multiobjective version of TEAM (Testing Electromagnetic Analysis Method) workshop problem 22, demonstrating promising results in terms of performance.

关键词： Optimization Conferences Monte Carlo methods Entropy Testing Electromagnetic analysis Histograms

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Multi-objective symbiotic search algorithm approaches for electromagnetic optimization

Multi-objective symbiotic search algorithm approaches for el...

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IEEE Conference on Electromagnetic Field Computation

作者： Helon Vicente Hultmann Ayala Carlos Eduardo Klein Viviana Cocco Mariani Leandro dos Santos Coelho Pontificia Universidade Catolica do Parana Curitiba PR BR Pontifical Catholic University of Parana (PUCPR) Industrial and Systems Engineering Graduate Program (PPGEPS) Curitiba PR Brazil Pontifical Catholic University of Parana (PUCPR) Mechanical Engineering Graduate Program (PPGEM) Curitiba PR Brazil Department of Electrical Engineering Federal University of Parana Curitiba PR Brazil

ISBN: (纸本)9781509010332

Optimization metaheuristics are a powerful way to deal with many electromagnetic optimization problems. Recently, the symbiotic organisms search (SOS) algorithm was proposed to solve single-objective optimization problems. SOS mimics the symbiotic relationship among the living beings. In order to extend the classical mono-objective SOS algorithm approach, this paper proposes a new multi-objective SOS (MOSOS) and an improved IMOSOS. Results on a multi-objective constrained brushless direct current (DC) motor design show that the MOSOS and IMOSOS present promising performance.

关键词： Optimization Brushless DC motors Symbiosis Algorithm design and analysis Organisms

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