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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026

引用

The Lancet Global Health 2023年第3期11卷 e385-e413页

作者： Micah, Angela E. Bhangdia, Kayleigh Cogswell, Ian E. Lasher, Dylan Lidral-Porter, Brendan Maddison, Emilie R. Nguyen, Trang Nhu Ngoc Patel, Nishali Pedroza, Paola Solorio, Juan Stutzman, Hayley Tsakalos, Golsum Wang, Yifeng Warriner, Wesley Zhao, Yingxi Zlavog, Bianca S. Abbafati, Cristiana Abbas, Jaffar Abbasi-Kangevari, Mohsen Abbasi-Kangevari, Zeinab Abdelmasseh, Michael Abdulah, Deldar Morad Abedi, Aidin Abegaz, Kedir Hussein Abhilash, E.S. Aboagye, Richard Gyan Abolhassani, Hassan Abrigo, Michael R.M. Abubaker Ali, Hiwa Abu-Gharbieh, Eman Adem, Mohammed Hussien Afzal, Muhammad Sohail Ahmadi, Ali Ahmed, Haroon Ahmed Rashid, Tarik Aji, Budi Akbarialiabad, Hossein Akelew, Yibeltal Al Hamad, Hanadi Alam, Khurshid Alanezi, Fahad Mashhour Alanzi, Turki M. Al-Hanawi, Mohammed Khaled Alhassan, Robert Kaba Aljunid, Syed Mohamed Almustanyir, Sami Al-Raddadi, Rajaa M. Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Amare, Azmeraw T. Ameyaw, Edward Kwabena Amini-Rarani, Mostafa Amu, Hubert Ancuceanu, Robert Andrei, Tudorel Anwar, Sumadi Lukman Appiah, Francis Aqeel, Muhammad Arabloo, Jalal Arab-Zozani, Morteza Aravkin, Aleksandr Y. Aremu, Olatunde Aruleba, Raphael Taiwo Athari, Seyyed Shamsadin Avila-Burgos, Leticia Ayanore, Martin Amogre Azari, Samad Baig, Atif Amin Bantie, Abere Tilahun Barrow, Amadou Baskaran, Pritish Basu, Sanjay Batiha, Abdul-Monim Mohammad Baune, Bernhard T. Berezvai, Zombor Bhardwaj, Nikha Bhardwaj, Pankaj Bhaskar, Sonu Boachie, Micheal Kofi Bodolica, Virginia Botelho, João Silva Botelho Braithwaite, Dejana Breitborde, Nicholas J.K. Busse, Reinhard Cahuana-Hurtado, Lucero Catalá-López, Ferrán Chansa, Collins Charan, Jaykaran Chattu, Vijay Kumar Chen, Simiao Chukwu, Isaac Sunday Dadras, Omid Dandona, Lalit Dandona, Rakhi Dargahi, Abdollah Debela, Sisay Abebe Denova-Gutiérrez, Edgar Desye, Belay Dharmaratne, Samath Dhamminda Diao, Nancy Doan, Linh Phuong Dodangeh, Milad dos Santos, Wendel Mombaque Doshmangir, Leila Dube, John Eini, Ebrahim El Sayed Zaki, Maysaa El Tantawi, Maha Enyew, Daniel Berhanie Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Applied Mathematics University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Nuffield Department of Medicine University of Oxford Oxford United Kingdom Department of Juridical and Economic Studies La Sapienza University Rome Italy Antai College of Economics Shanghai Jiao Tong University Shanghai China Non-communicable Diseases Research Center Tehran University of Medical Sciences Tehran Iran Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Multiple Sclerosis Research Center Tehran University of Medical Sciences Tehran Iran Children’s Medical Center Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Tehran Heart Center Tehran University of Medical Sciences Tehran Iran Faculty of Medicine Tehran University of Medical Sciences Tehran Iran National Institute for Health Research Tehran University of Medical Sciences Tehran Iran Department of Pharmacology Tehran University of Medical Sciences Tehran Iran Department of Cardiology Tehran University of Medical Sciences Tehran Iran Sina Trauma and Surgery Research Center Tehran University of Medical Sciences Tehran Iran Digestive Diseases Research Institute Tehran University of Medical Sciences Tehran Iran Department of Neurology Tehran University of Medical Sciences Tehran Iran Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Department of Epidemiology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Health Economics and Statistics Shahid Beheshti University of Medical Sciences Tehran Iran Department of Neurosurgery Shahid Beheshti University of Medical Sciences Tehran Iran Ophthalmic R

Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of ...

Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic;characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic;and examine expectations for future health spending and put into context the expected need for investment in pandemic preparedness. Methods: In this analysis of global health spending between 1990 and 2021, and prediction from 2021 to 2026, we estimated four sources of health spending: development assistance for health (DAH), government spending, out-of-pocket spending, and prepaid private spending across 204 countries and territories. We used the Organisation for Economic Co-operation and Development (OECD)'s Creditor Reporting System (CRS) and the WHO Global Health Expenditure Database (GHED) to estimate spending. We estimated development assistance for general health, COVID-19 response, and pandemic preparedness and response using a keyword search. Health spending estimates were combined with estimates of resources needed for pandemic prevention and preparedness to analyse future health spending patterns, relative to need. Findings: In 2019, at the onset of the COVID-19 pandemic, US$9·2 trillion (95% uncertainty interval [UI] 9·1–9·3) was spent on health worldwide. We found great disparities in the amount of resources devoted to health, with high-income countries spending $7·3 trillion (95% UI 7·2–7·4) in 2019;293·7 times the $24·8 billion (95% UI 24·3–25·3) spent by low-income countries in 2019. That same year, $43·1 billion in development assistance was provided

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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 (vol 395, pg 1779, 2020)

引用

LANCET 2020年第10239期395卷 1762-1762页

作者： Reiner, R. C., Jr. Hay, S., I Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Global Health School of Medicine University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States College of Health and Medical Sciences Haramaya University Harar Ethiopia Department of Epidemiology and Biostatistics Haramaya University Harar Ethiopia Department of Medical Laboratory Sciences Haramaya University Harar Ethiopia School of Nursing and Midwifery Haramaya University Harar Ethiopia School of Pharmacy Haramaya University Harar Ethiopia School of Public Health Haramaya University Harar Ethiopia Haramaya University Harar Ethiopia Advanced Diagnostic and Interventional Radiology Research Center Tehran University of Medical Sciences Tehran Iran Cancer Biology Research Center Tehran University of Medical Sciences Tehran Iran Cancer Research Institute Tehran University of Medical Sciences Tehran Iran Department of Economics and Management Sciences for Health Tehran University of Medical Sciences Tehran Iran Department of Environmental Health Engineering Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Department of Health Management and Economics Tehran University of Medical Sciences Tehran Iran Department of Microbiology Tehran University of Medical Sciences Tehran Iran Department of Pharmacology Tehran University of Medical Sciences Tehran Iran Digestive Diseases Research Institute Tehran University of Medical Sciences Tehran Iran Endocrinology and Metabolism Research Center Tehran University of Medical Sciences Tehran Iran Hematology-Oncology and Stem Cell Transplantation Research Center Tehran University of Medical Sciences Tehran Iran Iran National Institute of Health Research Tehran University of Medical Sciences Tehran Iran Metabolomics and

Summary Background Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea in...

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Publisher Correction: The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control

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BMC biology 2021年第1期19卷 150页

作者： Pia U Olafson Serap Aksoy Geoffrey M Attardo Greta Buckmeier Xiaoting Chen Craig J Coates Megan Davis Justin Dykema Scott J Emrich Markus Friedrich Christopher J Holmes Panagiotis Ioannidis Evan N Jansen Emily C Jennings Daniel Lawson Ellen O Martinson Gareth L Maslen Richard P Meisel Terence D Murphy Dana Nayduch David R Nelson Kennan J Oyen Tyler J Raszick José M C Ribeiro Hugh M Robertson Andrew J Rosendale Timothy B Sackton Perot Saelao Sonja L Swiger Sing-Hoi Sze Aaron M Tarone David B Taylor Wesley C Warren Robert M Waterhouse Matthew T Weirauch John H Werren Richard K Wilson Evgeny M Zdobnov Joshua B Benoit Livestock Arthropod Pests Research Unit USDA-ARS Kerrville TX USA. pia.olafson@usda.gov. Department of Epidemiology of Microbial Diseases Yale School of Public Health New Haven CT USA. Department of Entomology and Nematology University of California - Davis Davis CA USA. Livestock Arthropod Pests Research Unit USDA-ARS Kerrville TX USA. The Center for Autoimmune Genomics and Etiology Cincinnati Children's Hospital Medical Center Cincinnati OH USA. Department of Entomology Texas A & M University College Station TX USA. Department of Biological Sciences Wayne State University Detroit MI USA. Department of Electrical Engineering & Computer Science University of Tennessee Knoxville TN USA. Department of Biological Sciences University of Cincinnati Cincinnati OH USA. Department of Genetic Medicine and Development University of Geneva Medical School and Swiss Institute of Bioinformatics 1211 Geneva Switzerland. The European Molecular Biology Laboratory The European Bioinformatics Institute The Wellcome Genome Campus Hinxton CB10 1SD UK. Department of Entomology University of Georgia Athens GA USA. Department of Biology and Biochemistry University of Houston Houston TX USA. National Center for Biotechnology Information National Library of Medicine National Institutes of Health Bethesda MD USA. Arthropod-borne Animal Diseases Research Unit USDA-ARS Manhattan KS USA. Department of Microbiology Immunology and Biochemistry University of Tennessee Health Science Center Memphis TN USA. Section of Vector Biology Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases Rockville MD USA. Department of Entomology University of Illinois at Urbana-Champaign Urbana IL USA. Department of Biology Mount St. Joseph University Cincinnati OH USA. Informatics Group Faculty of Arts and Sciences Harvard University Cambridge MA USA. Department of Entomology Texas A&M AgriLife Research and Extension Center Stephenville

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Predicting breast tumor proliferation from whole-slide images: The TUPAC16 challenge

arXiv

引用

arXiv 2018年

作者： Veta, Mitko Heng, Yujing J. Stathonikos, Nikolas Bejnordi, Babak Ehteshami Beca, Francisco Wollmann, Thomas Rohr, Karl Shah, Manan A. Wang, Dayong Rousson, Mikael Hedlund, Martin Tellez, David Ciompi, Francesco Zerhouni, Erwan Lanyi, David Viana, Matheus Kovalev, Vassili Liauchuk, Vitali Phoulady, Hady Ahmady Qaiser, Talha Graham, Simon Rajpoot, Nasir Sjöblom, Erik Molin, Jesper Paeng, Kyunghyun Hwang, Sangheum Park, Sunggyun Jia, Zhipeng Chang, Eric I-Chao Xu, Yan Beck, Andrew H. Van Diest, Paul J. Pluim, Josien P.W. Medical Image Analysis Group Eindhoven University of Technology Eindhoven Netherlands Department of Pathology Beth Israel Deaconess Medical Center Harvard Medical School BostonMA United States Department of Pathology University Medical Center Utrecht Utrecht Netherlands Diagnostic Image Analysis Group Radboud University Medical Center Nijmegen Netherlands Department of Pathology Stanford University School of Medicine Biomedical Computer Vision Group University of Heidelberg BIOQUANT IPMB DKFZ Heidelberg Germany Harker School San Jose United States ContextVision AB Linköping Sweden Foundations of Cognitive Computing IBM Research Zürich Rüschlikon Switzerland Visual Analytics and Insights IBM Research Brazil Saõ Paulo Brazil Biomedical Image Analysis Department United Institute of Informatics Minsk Belarus Department of Computer Science and Engineering University of South Florida TampaFL United States Department of Computer Science University of Warwick Warwick United Kingdom Research Sectra Linköping Sweden Lunit Inc. Seoul Korea Republic of Institute for Interdisciplinary Information Sciences Tsinghua University Beijing China Microsoft Research Beijing China Biology and Medicine Engineering Beihang University Beijing China IBM Research Brazil

Tumor proliferation is an important biomarker indicative of the prognosis of breast cancer patients. Assessment of tumor proliferation in a clinical setting is a highly subjective and labor-intensive task. Previous ef... 详细信息

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Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM_2·5 air pollution, 1990–2019: an analysis of data from the Global Burden of Disease Study 2019

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The Lancet Planetary Health 2022年第7期6卷 e586-e600页

作者： Burkart, Katrin Causey, Kate Cohen, Aaron J Wozniak, Sarah S Salvi, Devashri Digvijay Abbafati, Cristiana Adekanmbi, Victor Adsuar, Jose C Ahmadi, Keivan Alahdab, Fares Al-Aly, Ziyad Alipour, Vahid Alvis-Guzman, Nelson Amegah, Adeladza Kofi Andrei, Catalina Liliana Andrei, Tudorel Ansari, Fereshteh Arabloo, Jalal Aremu, Olatunde Aripov, Timur Babaee, Ebrahim Banach, MacIej Barnett, Anthony Bärnighausen, Till Winfried Bedi, Neeraj Behzadifar, Masoud Béjot, Yannick Bennett, Derrick A Bensenor, Isabela M Bernstein, Robert S Bhattacharyya, Krittika Bijani, Ali Biondi, Antonio Bohlouli, Somayeh Breitner, Susanne Brenner, Hermann Butt, Zahid A Cámera, Luis Alberto Cantu-Brito, Carlos Carvalho, Felix Cerin, Ester Chattu, Vijay Kumar Chauhan, Bal Govind Choi, Jee-Young Jasmine Chu, Dinh-Toi Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Daryani, Ahmad Davletov, Kairat De Courten, Barbora Demeke, Feleke Mekonnen Denova-Gutiérrez, Edgar Dharmaratne, Samath Dhamminda Dhimal, Meghnath Diaz, Daniel Djalalinia, Shirin Duncan, Bruce B El Sayed Zaki, Maysaa Eskandarieh, Sharareh Fareed, Mohammad Farzadfar, Farshad Fattahi, Nazir Fazlzadeh, Mehdi Fernandes, Eduarda Filip, Irina Fischer, Florian Foigt, Nataliya A Freitas, Marisa Ghashghaee, Ahmad Gill, Paramjit Singh Ginawi, Ibrahim Abdelmageed Gopalani, Sameer Vali Guo, Yuming Gupta, Rajat Das Habtewold, Tesfa Dejenie Hamadeh, Randah R Hamidi, Samer Hankey, Graeme J Hasanpoor, Edris Hassen, Hamid Yimam Hay, Simon I Heibati, Behzad Hole, Michael K Hossain, Naznin Househ, Mowafa Irvani, Seyed Sina Naghibi Jaafari, Jalil Jakovljevic, Mihajlo Jha, Ravi Prakash Jonas, Jost B Jozwiak, Jacek Jerzy Kasaeian, Amir Kaydi, Neda Khader, Yousef Saleh Khafaie, Morteza Abdullatif Khan, Ejaz Ahmad Khan, Junaid Khan, Md Nuruzzaman Khatab, Khaled Khater, Amir M Kim, Yun Jin Kimokoti, Ruth W Kisa, Adnan Kivimäki, Mika Knibbs, Luke D Kosen, Soewarta Koul, Parvaiz A Koyanagi, Ai Defo, Barthelemy Kuate Kugbey, Nuworza Lauriola, Paolo Lee, Paul H Leili, Mostafa Lewycka, Sonia Li, Shanshan Lim, Lee-Ling Li Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Division of Plastic and Reconstructive Surgery University of Washington Seattle WA United States Research Insights and Innovation Seattle WA United States Health Effects Institute Boston MA United States School of Public Health Boston University Boston MA United States Department of Juridical and Economic Studies La Sapienza University Rome Italy Department of Population Medicine Cardiff University Cardiff United Kingdom Sport Science Department University of Extremadura Badajoz Spain School of Public Health Imperial College London London United Kingdom Department of Primary Care and Public Health Imperial College London London United Kingdom Mayo Evidence-based Practice Center Mayo Clinic Foundation for Medical Education and Research Rochester MN United States John T. Milliken Department of Internal Medicine Washington University in St. Louis St. Louis MO United States Clinical Epidemiology Center US Department of Veterans Affairs (VA) St Louis MO United States Health Management and Economics Research Center Iran University of Medical Sciences Tehran Iran Department of Health Economics Iran University of Medical Sciences Tehran Iran Preventive Medicine and Public Health Research Center Iran University of Medical Sciences Tehran Iran Pars Advanced and Minimally Invasive Medical Manners Research Center Iran University of Medical Sciences Tehran Iran Department of Community and Family Medicine Iran University of Medical Sciences Tehran Iran Research Group in Hospital Management and Health Policies Universidad de la Costa (University of the Coast) Barranquilla Colombia Research Group in Health Economics University of Cartagena Cartagena Colombia Department of Biomedical Science University of Cape Coast Cape Coast Ghana Cardiology Department Ca

Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalen...

Background: Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM_2·5 originating from ambient and household air pollution. Methods: We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM_2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure–response curve from the extracted relative risk estimates using the MR-BRT (meta-regression—Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM_2·5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM_2·5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings: In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM_2·5 exposure, with an estimated 3·78 (95% uncertainty interval 2·68–4·83) deaths per 100 000 population and 167 (117–223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13·4% (9·49–17·5) of deaths and 13·6% (9·73–17·9) of DALYs due to type 2 diabetes were contributed by ambient PM2·5, and 6·50% (4·22–9·53) of deaths and 5·92% (3·81–8·64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South Am

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids

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Nature 2023年第7965期618卷 E19-E20页

作者： Sarah E Graham Shoa L Clarke Kuan-Han H Wu Stavroula Kanoni Greg J M Zajac Shweta Ramdas Ida Surakka Ioanna Ntalla Sailaja Vedantam Thomas W Winkler Adam E Locke Eirini Marouli Mi Yeong Hwang Sohee Han Akira Narita Ananyo Choudhury Amy R Bentley Kenneth Ekoru Anurag Verma Bhavi Trivedi Hilary C Martin Karen A Hunt Qin Hui Derek Klarin Xiang Zhu Gudmar Thorleifsson Anna Helgadottir Daniel F Gudbjartsson Hilma Holm Isleifur Olafsson Masato Akiyama Saori Sakaue Chikashi Terao Masahiro Kanai Wei Zhou Ben M Brumpton Humaira Rasheed Sanni E Ruotsalainen Aki S Havulinna Yogasudha Veturi QiPing Feng Elisabeth A Rosenthal Todd Lingren Jennifer Allen Pacheco Sarah A Pendergrass Jeffrey Haessler Franco Giulianini Yuki Bradford Jason E Miller Archie Campbell Kuang Lin Iona Y Millwood George Hindy Asif Rasheed Jessica D Faul Wei Zhao David R Weir Constance Turman Hongyan Huang Mariaelisa Graff Anubha Mahajan Michael R Brown Weihua Zhang Ketian Yu Ellen M Schmidt Anita Pandit Stefan Gustafsson Xianyong Yin Jian'an Luan Jing-Hua Zhao Fumihiko Matsuda Hye-Mi Jang Kyungheon Yoon Carolina Medina-Gomez Achilleas Pitsillides Jouke Jan Hottenga Gonneke Willemsen Andrew R Wood Yingji Ji Zishan Gao Simon Haworth Ruth E Mitchell Jin Fang Chai Mette Aadahl Jie Yao Ani Manichaikul Helen R Warren Julia Ramirez Jette Bork-Jensen Line L Kårhus Anuj Goel Maria Sabater-Lleal Raymond Noordam Carlo Sidore Edoardo Fiorillo Aaron F McDaid Pedro Marques-Vidal Matthias Wielscher Stella Trompet Naveed Sattar Line T Møllehave Betina H Thuesen Matthias Munz Lingyao Zeng Jianfeng Huang Bin Yang Alaitz Poveda Azra Kurbasic Claudia Lamina Lukas Forer Markus Scholz Tessel E Galesloot Jonathan P Bradfield E Warwick Daw Joseph M Zmuda Jonathan S Mitchell Christian Fuchsberger Henry Christensen Jennifer A Brody Mary F Feitosa Mary K Wojczynski Michael Preuss Massimo Mangino Paraskevi Christofidou Niek Verweij Jan W Benjamins Jorgen Engmann Rachel L Kember Roderick C Slieker Ken Sin Lo Nuno R Zilhao Phuong Le Marcus E Kleber Graciela E Delgado Shaofeng Huo Dai Department of Internal Medicine Division of Cardiology University of Michigan Ann Arbor MI USA. VA Palo Alto Health Care System Palo Alto CA USA. Department of Medicine Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA. Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Department of Biostatistics and Center for Statistics Genetics University of Michigan Ann Arbor MI USA. Department of Genetics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Clinical Pharmacology William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK. Endocrinology Boston Children's Hospital Boston MA USA. Medical and Population Genetics Broad Institute Cambridge MA USA. Department of Genetic Epidemiology University of Regensburg Regensburg Germany. McDonnell Genome Institute and Department of Medicine Washington University St Louis MO USA. Department of Precision Medicine Division of Genome Science National Institute of Health Cheongju-si South Korea. Tohoku Medical Megabank Organization Tohoku University Sendai Japan. Sydney Brenner Institute for Molecular Bioscience Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa. Center for Research on Genomics and Global Health National Human Genome Research Institute National Institutes of Health Bethesda MD USA. Blizard Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Wellcome Sanger Institute Hinxton UK. Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA. Atlanta VA Health Care System Decatur GA USA. Malcolm Randall VA Medical Center Gainesville FL USA. Division of Vascular Sur

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EnzyNet: Enzyme classification using 3D convolutional neural networks on spatial representation

arXiv

引用

arXiv 2017年

作者： Amidi, Afshine Amidi, Shervine Vlachakis, Dimitrios Megalooikonomou, Vasileios Paragios, Nikos Zacharaki, Evangelia I. Massachusetts Institute of Technology Cambridge United States Center for Visual Computing Department of Applied Mathematics École Centrale Paris CentraleSupélec Chátenay-Malabry France Mdakm Group Department of Computer Engineering and Informatics University of Patras Patras Greece

During the past decade, with the significant progress of computational power as well as ever-rising data availability, deep learning techniques became increasingly popular due to their excellent performance on compute... 详细信息

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Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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The Lancet 2020年第10258期396卷 1204-1222页

作者： Abbafati, Cristiana Abbas, Kaja M. Abbasi, Mohammad Abbasifard, Mitra Abbasi-Kangevari, Mohsen Abbastabar, Hedayat Abd-Allah, Foad Abdelalim, Ahmed Abdollahi, Mohammad Abdollahpour, Ibrahim Abedi, Aidin Abedi, Parisa Abegaz, Kedir Hussein Abolhassani, Hassan Abosetugn, Akine Eshete Aboyans, Victor Abrams, Elissa M. Abreu, Lucas Guimarães Abrigo, Michael R.M. Abu Haimed, Abdulaziz Khalid Abualhasan, Ahmed Abu-Gharbieh, Eman Abu-Raddad, Laith Jamal Abushouk, Abdelrahman I. Acebedo, Alyssa Ackerman, Ilana N. Adabi, Maryam Adair, Tim Adamu, Abdu A. Adebayo, Oladimeji M. Adedeji, Isaac Akinkunmi Adekanmbi, Victor Adelson, Jaimie D. Adeoye, Abiodun Moshood Adetokunboh, Olatunji O. Adham, Davoud Advani, Shailesh M. Afarideh, Mohsen Afshari, Mahdi Afshin, Ashkan Agardh, Emilie E. Agarwal, Gina Agasthi, Pradyumna Agesa, Kareha M. Aghaali, Mohammad Aghamir, Seyed Mohammad Kazem Agrawal, Anurag Ahmad, Tauseef Ahmadi, Alireza Ahmadi, Keivan Ahmadi, Mehdi Ahmadieh, Hamid Ahmadpour, Ehsan Ahmed, Muktar Beshir Aji, Budi Akalu, Temesgen Yihunie Akinyemi, Rufus Olusola Akinyemiju, Tomi Akombi, Blessing Akunna, Chisom Joyqueenet Alahdab, Fares Al-Aly, Ziyad Alam, Khurshid Alam, Noore Alam, Samiah Alam, Tahiya Alanezi, Fahad Mashhour Alanzi, Turki M. Albertson, Samuel B. Alcalde-Rabanal, Jacqueline Elizabeth Alema, Niguse Meles Alemu, Biresaw Wassihun Alemu, Yihun Mulugeta Alhabib, Khalid F. Alhassan, Robert Kaba Ali, Muhammad Ali, Saqib Alicandro, Gianfranco Alijanzadeh, Mehran Alinia, Cyrus Alipour, Vahid Alizade, Hesam Aljunid, Syed Mohamed Alla, François Allebeck, Peter Almadi, Majid Abdulrahman Hamad Almasi, Ali Almasi-Hashiani, Amir Almasri, Nihad A. Al-Mekhlafi, Hesham M. Almulhim, Abdulaziz M. Alonso, Jordi Al-Raddadi, Rajaa M. Altirkawi, Khalid A. Alumran, Arwa Khalid Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Amare, Azmeraw T. Amare, Bekalu Amini, Saeed Amini-Rarani, Mostafa Aminorroaya, Arya Amiri, Fatemeh Amit, Arianna Maever L. Amugsi, Dickson A. Amul, Gianna Gayle Herrera Anbesu, Etsay Woldu Ancuceanu, Robert Anderl Department of Juridical and Economic Studies La Sapienza University Rome Italy Department of Infectious Disease Epidemiology London School of Hygiene and Tropical Medicine London United Kingdom Social Determinants of Health Research Center Tehran Iran Department of Neurology Cairo University Cairo Egypt School of Pharmacy Tehran Iran The Institute of Pharmaceutical Sciences (TIPS) Tehran Iran Neuroscience Research Center Isfahan University of Medical Sciences Isfahan Iran Biostatistics Department Near East University Nicosia Cyprus Biostatistics and Health Informatics Madda Walabu University Bale Robe Ethiopia Research Center for Immunodeficiencies Tehran Iran Karolinska University Hospital Huddinge Sweden Department of Cardiology Dupuytren University Hospital Limoges France University of Limoges Limoges France Department of Pediatric Dentistry Federal University of Minas Gerais Belo Horizonte Brazil Department of Research Philippine Institute for Development Studies Quezon City Philippines Department of Healthcare Policy and Research Weill Cornell Medical College in Qatar Doha Qatar Harvard Medical School Boston MA United States Department of Medicine Ain Shams University Cairo Egypt Hamadan University of Medical Sciences Hamadan Iran School of Medicine Cardiff University Cardiff United Kingdom School of Laboratory Medicine and Science University College Hospital Ibadan Ibadan Nigeria Institute of Cardiovascular Diseases University of Ibadan Ibadan Nigeria Centre of Excellence for Epidemiological Modelling and Analysis Stellenbosch University Cape Town South Africa Department of Global Health Stellenbosch University Cape Town South Africa School of Health Ardabil University of Medical Science Ardabil Iran Social Behavioral Research Branch National Institute of Health Bethesda MD United States Department of Oncology Georgetown University Washington DC DC United States Department of Health Metrics Sciences School of Medicine Seattle WA

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. ...

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw value

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Search for W′ bosons decaying to a top and a bottom quark in leptonic final states in proton-proton collisions at s = 13 TeV

引用

Journal of High Energy Physics 2024年第5期2024卷 46页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Hussain, P.S. Jeitler, M. Krammer, N. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Van Mechelen, P. Bols, E.S. D’Hondt, J. Dansana, S. De Moor, A. Delcourt, M. El Faham, H. Lowette, S. Makarenko, I. Müller, D. Sahasransu, A.R. Tavernier, S. Tytgat, M. Van Putte, S. Vannerom, D. Clerbaux, B. De Lentdecker, G. Favart, L. Hohov, D. Jaramillo, J. Khalilzadeh, A. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Pétré, L. Postiau, N. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. De Coen, M. Dobur, D. Hong, Y. Knolle, J. Lambrecht, L. Mestdach, G. Rendón, C. Samalan, A. Skovpen, K. Van Den Bossche, N. Wezenbeek, L. Benecke, A. Bruno, G. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sa. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. Menezes De Oliveira, T. Moraes, A. Rebello Teles, P. Soeiro, M. Aldá Júnior, W.L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Fonseca De Souza, S. Martins, J. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Guo, Q. Javaid, T. Mittal, M. Yuan, L. Bauer, G. Hu, Z. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Monti, F. Sharma, R. Song, J.N. Tao, J. Wang, C. Wang, J. Wang, Z. Zhang, H. Agapitos, A. Ban, Y. Lev Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-Sen University Guangzhou China University of Science and Technology of China Hefei China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) — Fudan University Shanghai China Zhejiang University Zhejiang Hangzhou China Universidad de Los Andes Bogota Colombia Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia University of Split Faculty of Science Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysics Tallinn Estonia Department of Physics

A search for W′ bosons decaying to a top and a bottom quark in final states including an electron or a muon is performed with the CMS detector at the LHC. The analyzed data correspond to an integrated luminosity of 1... 详细信息

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Measurement of the τ lepton polarization in Z boson decays in proton-proton collisions at (Formula presented.)

引用

Journal of High Energy Physics 2024年第1期2024卷 101页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Hussain, P.S. Jeitler, M. Krammer, N. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Van Mechelen, P. Bols, E.S. D’Hondt, J. Dansana, S. De Moor, A. Delcourt, M. El Faham, H. Lowette, S. Makarenko, I. Müller, D. Sahasransu, A.R. Tavernier, S. Tytgat, M. Van Putte, S. Vannerom, D. Clerbaux, B. De Lentdecker, G. Favart, L. Hohov, D. Jaramillo, J. Khalilzadeh, A. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Pétré, L. Postiau, N. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. De Coen, M. Dobur, D. Hong, Y. Knolle, J. Lambrecht, L. Mestdach, G. Rendón, C. Samalan, A. Skovpen, K. Van Den Bossche, N. Wezenbeek, L. Benecke, A. Bruno, G. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sa. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. Menezes De Oliveira, T. Moraes, A. Rebello Teles, P. Soeiro, M. Aldá Júnior, W.L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Fonseca De Souza, S. Martins, J. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Guo, Q. Javaid, T. Mittal, M. Yuan, L. Bauer, G. Hu, Z. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Monti, F. Sharma, R. Song, J.N. Tao, J. Wang, C. Wang, J. Wang, Z. Zhang, H. Agapitos, A. Ban, Y. Lev Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-Sen University Guangzhou China University of Science and Technology of China Hefei China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) — Fudan University Shanghai China Zhejiang University Zhejiang Hangzhou China Universidad de Los Andes Bogota Colombia Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia University of Split Faculty of Science Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysics Tallinn Estonia Department of Physics

The polarization of τ leptons is measured using leptonic and hadronic τ lepton decays in Z → τ+ τ− events in proton-proton collisions at (Formula presented.) recorded by CMS at the CERN LHC with an integrated lum... 详细信息

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