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Diffuse supernova neutrino background search at Super-Kamiokande

Physical Review D 2021年第12期104卷 122002-122002页

作者： K. Abe C. Bronner Y. Hayato K. Hiraide M. Ikeda S. Imaizumi J. Kameda Y. Kanemura Y. Kataoka S. Miki M. Miura S. Moriyama Y. Nagao M. Nakahata S. Nakayama T. Okada K. Okamoto A. Orii G. Pronost H. Sekiya M. Shiozawa Y. Sonoda Y. Suzuki A. Takeda Y. Takemoto A. Takenaka H. Tanaka S. Watanabe T. Yano S. Han T. Kajita K. Okumura T. Tashiro J. Xia G. D. Megias D. Bravo-Berguño L. Labarga Ll. Marti B. Zaldivar B. W. Pointon F. d. M. Blaszczyk E. Kearns J. L. Raaf J. L. Stone L. Wan T. Wester J. Bian N. J. Griskevich W. R. Kropp S. Locke S. Mine M. B. Smy H. W. Sobel V. Takhistov J. Hill J. Y. Kim I. T. Lim R. G. Park B. Bodur K. Scholberg C. W. Walter S. Cao L. Bernard A. Coffani O. Drapier S. El Hedri A. Giampaolo M. Gonin Th. A. Mueller P. Paganini B. Quilain T. Ishizuka T. Nakamura J. S. Jang J. G. Learned L. H. V. Anthony D. Martin M. Scott A. A. Sztuc Y. Uchida V. Berardi M. G. Catanesi E. Radicioni N. F. Calabria L. N. Machado G. De Rosa G. Collazuol F. Iacob M. Lamoureux M. Mattiazzi N. Ospina L. Ludovici Y. Maekawa Y. Nishimura M. Friend T. Hasegawa T. Ishida T. Kobayashi M. Jakkapu T. Matsubara T. Nakadaira K. Nakamura Y. Oyama K. Sakashita T. Sekiguchi T. Tsukamoto Y. Kotsar Y. Nakano H. Ozaki T. Shiozawa A. T. Suzuki Y. Takeuchi S. Yamamoto A. Ali Y. Ashida J. Feng S. Hirota T. Kikawa M. Mori T. Nakaya R. A. Wendell K. Yasutome P. Fernandez N. McCauley P. Mehta K. M. Tsui Y. Fukuda Y. Itow H. Menjo T. Niwa K. Sato M. Tsukada J. Lagoda S. M. Lakshmi P. Mijakowski J. Zalipska J. Jiang C. K. Jung C. Vilela M. J. Wilking C. Yanagisawa K. Hagiwara M. Harada T. Horai H. Ishino S. Ito H. Kitagawa Y. Koshio W. Ma N. Piplani S. Sakai G. Barr D. Barrow L. Cook A. Goldsack S. Samani D. Wark F. Nova T. Boschi F. Di Lodovico J. Gao J. Migenda M. Taani S. Zsoldos J. Y. Yang S. J. Jenkins M. Malek J. M. McElwee O. Stone M. D. Thiesse L. F. Thompson H. Okazawa S. B. Kim J. W. Seo I. Yu K. Nishijima M. Koshiba K. Iwamoto K. Nakagiri Y. Nakajima N. Ogawa M. Yokoyama K. Martens M. R. Vagins M. Kuze S. Izumiyama T. Yoshida M. Kamioka Observatory Institute for Cosmic Ray Research University of Tokyo Kamioka Gifu 506-1205 Japan Kavli Institute for the Physics and Mathematics of the Universe (WPI) The University of Tokyo Institutes for Advanced Study University of Tokyo Kashiwa Chiba 277-8583 Japan Department of Physics Yokohama National University Yokohama Kanagawa 240-8501 Japan Research Center for Cosmic Neutrinos Institute for Cosmic Ray Research University of Tokyo Kashiwa Chiba 277-8582 Japan Institute for Cosmic Ray Research University of Tokyo Kashiwa Chiba 277-8582 Japan Department of Theoretical Physics University Autonoma Madrid 28049 Madrid Spain Department of Physics British Columbia Institute of Technology Burnaby BC V5G 3H2 Canada TRIUMF 4004 Wesbrook Mall Vancouver BC V6T2A3 Canada Department of Physics Boston University Boston Massachusetts 02215 USA Department of Physics and Astronomy University of California Irvine Irvine California 92697-4575 USA Department of Physics California State University Dominguez Hills Carson California 90747 USA Institute for Universe and Elementary Particles Chonnam National University Gwangju 61186 Korea Department of Physics Duke University Durham North Carolina 27708 USA Institute For Interdisciplinary Research in Science and Education ICISE Quy Nhon 55121 Vietnam Ecole Polytechnique IN2P3-CNRS Laboratoire Leprince-Ringuet F-91120 Palaiseau France Junior College Fukuoka Institute of Technology Fukuoka Fukuoka 811-0295 Japan Department of Physics Gifu University Gifu Gifu 501-1193 Japan GIST College Gwangju Institute of Science and Technology Gwangju 500-712 Korea Department of Physics and Astronomy University of Hawaii Honolulu Hawaii 96822 USA Department of Physics Imperial College London London SW7 2AZ United Kingdom Dipartimento Interuniversitario di Fisica INFN Sezione di Bari and Università e Politecnico di Bari I-70125 Bari Italy Dipartimento di Fisica INFN Sezione di Napoli and Università di Napoli

We have conducted a new search for the diffuse supernova neutrino background (DSNB) flux at Super-Kamiokande (SK), with a 22.5×2970−kton·day exposure from its fourth operational phase IV. With the new analysis we improve on the existing background reduction techniques and systematic uncertainties and take advantage of an improved neutron tagging algorithm to lower the energy threshold compared to the previous phases of SK. This allows for setting the world’s most stringent upper limit on the extraterrestrial ν¯e flux, for neutrino energies below 31.3 MeV. The SK-IV results are combined with the ones from the first three phases of SK to perform a joint analysis using 22.5×5823 kton·days of data. This analysis has the world’s best sensitivity to the DSNB ν¯e flux, comparable to the predictions from various models. For neutrino energies larger than 17.3 MeV, the new combined 90% CL upper limits on the DSNB ν¯e flux lie around 2.7 cm−2·sec−1, strongly disfavoring the most optimistic predictions. Finally, potentialities of the gadolinium phase of SK and the future Hyper-Kamiokande experiment are discussed.

关键词： Extrasolar neutrino astronomy

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Design of customer knowledge management system for Aglaonema Nursery in South Tangerang, Indonesia

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IOP Conference Series: Materials Science and engineering 2017年第1期277卷

作者： D Sugiarto I Mardianto TS Dewayana M Khadafi Faculty of Industrial Technology Information System Program Trisakti University Jakarta 11440 Indonesia Faculty of Industrial Technology Informatics Program Trisakti University Jakarta 11440 Indonesia Faculty of Industrial Technology Master of Industrial Engineering Program Trisakti University Jakarta 11440 Indonesia

The purpose of this paper is to describe the design of customer knowledge management system to support customer relationship management activities for an aglaonema nursery in South Tangerang, Indonesia. System. The steps were knowledge identification (knowledge about customer, knowledge from customer, knowledge for customer), knowledge capture, codification, analysis of system requirement and create use case and activity diagram. The result showed that some key knowledge were about supporting customer in plant care (know how) and types of aglaonema including with the prices (know what). That knowledge for customer then codified and shared in knowledge portal website integrated with social media. Knowledge about customer were about customers and their behaviour in purchasing aglaonema. Knowledge from customer were about feedback, favorite and customer experience. Codified knowledge were placed and shared using content management system based on wordpress.

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Analysis of Power Generating Speed Bumps Made of Concrete Foam Composite

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IOP Conference Series: Materials Science and engineering 2017年第1期180卷

作者： B Syam M Muttaqin D Hastrino A Sebayang W S Basuki M Sabri S Abda Impact and Fracture Research Center Dept. of Mechanical Engineering Faculty of Engineering University of Sumatera Utara (USU Graduate Student MechEngr Study Program USU Undergraduate Student Dept of MechEngr Study USU Dept. of Chemistry Faculty of Science University of Sumatera Utara Graduate student Dept. of Mech. Engr Faculty of Engineering University of Sumatera Utara

This paper discusses the analysis of speed bump made of concrete foam composite which is used to generate electrical power. Speed bumps are designed to decelerate the speed of vehicles before passing through toll gates, public areas, or any other safety purposes. In Indonesia a speed bump should be designed in the accordance with KM Menhub 3 year 1994. In this research, the speed bump was manufactured with dimensions and geometry comply to the regulation mentioned above. Concrete foam composite speed bumps were used due to its light weight and relatively strong to receive vertical forces from the tyres of vehicles passing over the bumps. The reinforcement materials are processed from empty fruit bunch of oil palm. The materials were subjected to various tests to obtain its physical and mechanical properties. To analyze the structure stability of the speed bumps some models were analyzed using a FEM-based numerical softwares. It was obtained that the speed bumps coupled with polymeric composite bar (3 inches in diameter) are significantly reduce the radial stresses. In addition, the speed bumps equipped with polymeric composite casing or steel casing are also suitable for use as part of system components in producing electrical energy.

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Mechanical Response of Open Channel Cover Made of Concrete Foam Due to External Loadings

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Journal of Physics: Conference Series 2017年第1期801卷

作者： Bustami Syam Alexander Sebayang Indra Gunawan Maraghi Muttaqin Herry Darmadi WS Basuki M. Sabri S. Abda Impact and Fracture Research Center Dept. of Mechanical Engineering Faculty of Engineering University of Sumatera Utara (USU Graduate Student MechEngr Study Program USU Undergraduate Student Dept of MechEngr Study USU Dept. of Chemistry Faculty of Science University of Sumatera Utara Graduate student Dept. of Mech. Engr Faculty of Engineering University of Sumatera Utara

Open channel conduit is commonly constructed on side roadway, car park area, etc., with the aims to collect rainwater or seapage water. To avoid garbages following the waterflow, the conduit is equipped with adequate cover. In addition, the cover can also be functioned for temporary car park area. Thus, the conduit cover should strong enough to sustain external loading. This paper discusses the design and response of the conduit cover using finite element software ANSYS MECHANICAL version 17.5.

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Training system using ground reaction force of the affected leg

Training system using ground reaction force of the affected ...

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SICE Annual Conference

作者： Ryoichiro Shiraishi Hiroaki Kawamoto Yoshiyuki Sankai Ph. D. Program in Empowerment Informatics University of Tsukuba Ibaraki Japan Faculty of Engineering University of Tsukuba Ibaraki Japan

ISBN: (纸本)9781509009374

Most patients with a paralyzed leg have difficulty in putting the body weight on the heel when they stand up, as well as diminished motor function of the affected part. This paper proposes a new training system for increasing the heel load of the affected leg in several postures. The developed system integrates Ground Reaction Force (GRF) sensors and a graphical monitor with a motion support device. The GRF sensors measure the load of the heel and toe on both legs and the users can recognize their motor information by looking at the monitor. The users can also hold their standing position and half-rising posture by using the motion support device. A basic experiment confirmed that the GRF sensors have measurement accuracy within 5 % error and measures the GRF of the toe and the heel part separately. We carried out a feasibility experiment in two patients to confirm that the users were able to conduct the training by using the system, and the users increased the GRF of the heel part. All the participants recognized their movement of the affected leg by looking at the monitor, and increased the GRF of the heel part when the visual motor information was provided. Moreover, the orthosis decreased the number of times that spasticity occurred and the results suggest that the training is feasible, and the system is effective in helping patients with the affected leg to conduct the training for increasing the GRF of the heel part.

关键词： Training Legged locomotion Monitoring Strain Safety Sensor systems

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Proton emission in ultraperipheral Pb-Pb collisions at sNN=5.02 TeV

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Physical Review C 2025年第5期111卷 054906-054906页

作者： S. Acharya A. Agarwal G. Aglieri Rinella L. Aglietta M. Agnello N. Agrawal Z. Ahammed S. Ahmad S. U. Ahn I. Ahuja A. Akindinov V. Akishina M. Al-Turany D. Aleksandrov B. Alessandro H. M. Alfanda R. Alfaro Molina B. Ali A. Alici N. Alizadehvandchali A. Alkin J. Alme G. Alocco T. Alt A. R. Altamura I. Altsybeev J. R. Alvarado C. O. R. Alvarez M. N. Anaam C. Andrei N. Andreou A. Andronic E. Andronov V. Anguelov F. Antinori P. Antonioli N. Apadula L. Aphecetche H. Appelshäuser C. Arata S. Arcelli R. Arnaldi J. G. M. C. A. Arneiro I. C. Arsene M. Arslandok A. Augustinus R. Averbeck D. Averyanov M. D. Azmi H. Baba A. Badalà J. Bae Y. Bae Y. W. Baek X. Bai R. Bailhache Y. Bailung R. Bala A. Baldisseri B. Balis Z. Banoo V. Barbasova F. Barile L. Barioglio M. Barlou B. Barman G. G. Barnaföldi L. S. Barnby E. Barreau V. Barret L. Barreto C. Bartels K. Barth E. Bartsch N. Bastid S. Basu G. Batigne D. Battistini B. Batyunya D. Bauri J. L. Bazo Alba I. G. Bearden C. Beattie P. Becht D. Behera I. Belikov A. D. C. Bell Hechavarria F. Bellini R. Bellwied S. Belokurova L. G. E. Beltran Y. A. V. Beltran G. Bencedi A. Bensaoula S. Beole Y. Berdnikov A. Berdnikova L. Bergmann M. G. Besoiu L. Betev P. P. Bhaduri A. Bhasin B. Bhattacharjee L. Bianchi J. Bielčík J. Bielčíková A. P. Bigot A. Bilandzic A. Binoy G. Biro S. Biswas N. Bize J. T. Blair D. Blau M. B. Blidaru N. Bluhme C. Blume F. Bock T. Bodova J. Bok L. Boldizsár M. Bombara P. M. Bond G. Bonomi H. Borel A. Borissov A. G. Borquez Carcamo E. Botta Y. E. M. Bouziani D. C. Brandibur L. Bratrud P. Braun-Munzinger M. Bregant M. Broz G. E. Bruno V. D. Buchakchiev M. D. Buckland D. Budnikov H. Buesching S. Bufalino P. Buhler N. Burmasov Z. Buthelezi A. Bylinkin S. A. Bysiak J. C. Cabanillas Noris M. F. T. Cabrera H. Caines A. Caliva E. Calvo Villar J. M. M. Camacho P. Camerini F. D. M. Canedo S. L. Cantway M. Carabas A. A. Carballo F. Carnesecchi R. Caron L. A. D. Carvalho J. Castillo Castellanos M. Castoldi F. Catalano S. Cattaruzzi R. Cerri I. Chakaberia P. Chakraborty S. Chandra Université Clermont Auvergne CNRS/IN2P3 LPC Clermont-Ferrand France Variable Energy Cyclotron Centre Homi Bhabha National Institute Kolkata India European Organization for Nuclear Research (CERN) Geneva Switzerland Dipartimento di Fisica dell'Università and Sezione INFN Turin Italy Dipartimento DISAT del Politecnico and Sezione INFN Turin Italy Dipartimento di Fisica e Astronomia dell'Università and Sezione INFN Bologna Italy Department of Physics Aligarh Muslim University Aligarh India Korea Institute of Science and Technology Information Daejeon Republic of Korea Faculty of Science P.J. Šafárik University Košice Slovak Republic Affiliated with an institute covered by a cooperation agreement with CERN Frankfurt Institute for Advanced Studies Johann Wolfgang Goethe-Universität Frankfurt Frankfurt Germany Research Division and ExtreMe Matter Institute EMMI GSI Helmholtzzentrum für Schwerionenforschung GmbH Darmstadt Germany INFN Sezione di Torino Turin Italy Central China Normal University Wuhan China Instituto de Física Universidad Nacional Autónoma de México Mexico City Mexico University of Houston Houston Texas USA Sungkyunkwan University Suwon City Republic of Korea Department of Physics and Technology University of Bergen Bergen Norway INFN Sezione di Cagliari Cagliari Italy Institut für Kernphysik Johann Wolfgang Goethe-Universität Frankfurt Frankfurt Germany INFN Sezione di Bari Bari Italy Physik Department Technische Universität München Munich Germany High Energy Physics Group Universidad Autónoma de Puebla Puebla Mexico Horia Hulubei National Institute of Physics and Nuclear Engineering Bucharest Romania University of Derby Derby United Kingdom Universität Münster Institut für Kernphysik Münster Germany Physikalisches Institut Ruprecht-Karls-Universität Heidelberg Heidelberg Germany INFN Sezione di Padova Padova Italy INFN Sezione di Bologna Bologna Italy Lawrence Berkeley National Laboratory Berkeley California USA SUBATECH I

The first measurements of proton emission accompanied by neutron emission in the electromagnetic dissociation (EMD) of Pb208 nuclei in the ALICE experiment at the Large Hadron Collider are presented. The EMD protons and neutrons emitted at very forward rapidities are detected by the proton and neutron zero degree calorimeters of the ALICE experiment. The emission cross sections of zero, one, two, and three protons accompanied by at least one neutron were measured in ultraperipheral Pb208−Pb208 collisions at a center-of-mass energy per nucleon pair sNN=5.02TeV. The 0p and 3p cross sections are described by the RELDIS model within their measurement uncertainties, while the 1p and 2p cross sections are underestimated by the model by 17–25%. According to this model, these 0p, 1p, 2p, and 3p cross sections are associated, respectively, with the production of various isotopes of Pb, Tl, Hg, and Au in the EMD of Pb208. The cross sections of the emission of a single proton accompanied by the emission of one, two, or three neutrons in EMD were also measured. The data are significantly overestimated by the RELDIS model, which predicts that the (1p,1n), (1p,2n), and (1p,3n) cross sections are very similar to the cross sections for the production of the thallium isotopes Tl206,205,204.

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Web based testing application security system using semantic comparison method

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IOP Conference Series: Materials Science and engineering 2018年第1期420卷

作者： Akbar Iskandar Muhammad Resa Fahlepi Tuasamu Suryadi Syamsu M Mansyur Tri Listyorini Sulfikar Sallu S Supriyono Kundharu Saddhono Darmawan Napitupulu Robbi Rahim Informatics Engineering STMIK AKBA Makassar Indonesia. Graduate Program Universitas Negeri Makassar Makassar Indonesia. Informatics Engineering Universitas Maria Kudus Central Java Indonesia. Computer Information Systems Universitas Sembilan Belas November Kolaka Indonesia. Department of Geography Education Universitas Prof Dr Hazairin SH Bengkulu Indonesia. Indonesian Language Education Departement Faculty of Teacher Training and Education Universitas Sebelas Maret Surakarta Indonesia. Research Center for Quality System and Testing Technology Indonesian Institute of Sciences Indonesia. Sekolah Tinggi Ilmu Manajemen Sukma Medan Indonesia

Computer and web security system is an attempt to avoid attacks from crackers because a form and method of crime on internet network can not be predicted. Therefore, we just keep trying to use various methods in securing the system that is running. It is the same in web testing that can be accessed online by people who are not responsible from along distance to change and remove the test results or even damage the web testing system. So, the purpose of this paper is to design and implement web security testing system by using semantic comparison method to avoid structured query language injection (SQLI) attack and to do security on web testing application using Message Digest 5 encryption (MD5). Research data were obtained by using direct observation and documentation and literature review. After the design and application of the system, it can be obtained that by using semantic comparison method in web testing can prevent the occurrence of SQL injection attacks and can secure account from web testing users by using MD5.

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Proton acceleration in thermonuclear nova explosions revealed by gamma rays

arXiv

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arXiv 2022年

作者： Acciari, V.A. Ansoldi, S. Antonelli, L.A. Arbet Engels, A. Artero, M. Asano, K. Baack, D. Babić, A. Baquero, A. Barres de Almeida, U. Barrio, J.A. Batković, I. Becerra González, J. Bednarek, W. Bellizzi, L. Bernardini, E. Bernardos, M. Berti, A. Besenrieder, J. Bhattacharyya, W. Bigongiari, C. Biland, A. Blanch, O. Bökenkamp, H. Bonnoli, G. Bošnjak, Ž. Busetto, G. Carosi, R. Ceribella, G. Cerruti, M. Chai, Y. Chilingarian, A. Cikota, S. Colak, S.M. Colombo, E. Contreras, J.L. Cortina, J. Covino, S. D'Amico, G. D'Elia, V. Da Vela, P. Dazzi, F. De Angelis, A. De Lotto, B. Del Popolo, A. Delfino, M. Delgado, J. Delgado Mendez, C. Depaoli, D. Di Pierro, F. Di Venere, L. Do Souto Espiñeira, E. Dominis Prester, D. Donini, A. Dorner, D. Doro, M. Elsaesser, D. Fallah Ramazani, V. Fariña Alonso, L. Fattorini, A. Fonseca, M.V. Font, L. Fruck, C. Fukami, S. Fukazawa, Y. García López, R.J. Garczarczyk, M. Gasparyan, S. Gaug, M. Giglietto, N. Giordano, F. Gliwny, P. Godinović, N. Green, J.G. Green, D. Hadasch, D. Hahn, A. Hassan, T. Heckmann, L. Herrera, J. Hoang, J. Hrupec, D. Hütten, M. Inada, T. Ishio, K. Iwamura, Y. Jiménez Martínez, I. Jormanainen, J. Jouvin, L. Kerszberg, D. Kobayashi, Y. Kubo, H. Kushida, J. Lamastra, A. Lelas, D. Leone, F. Lindfors, E. Linhoff, L. Lombardi, S. Longo, F. López-Coto, R. López-Moya, M. López-Oramas, A. Loporchio, S. Machado de Oliveira Fraga, B. Maggio, C. Majumdar, P. Makariev, M. Mallamaci, M. Maneva, G. Manganaro, M. Mannheim, K. Maraschi, L. Mariotti, M. Martínez, M. Mas Aguilar, A. Mazin, D. Menchiari, S. Mender, S. Mićanović, S. Miceli, D. Miener, T. Miranda, J.M. Mirzoyan, R. Molina, E. Moralejo, A. Morcuende, D. Moreno, V. Moretti, E. Nakamori, T. Nava, L. Neustroev, V. Nievas Rosillo, M. Nigro, C. Nilsson, K. Nishijima, K. Noda, K. Nozaki, S. Ohtani, Y. Oka, T. Otero-Santos, J. Paiano, S. Palatiello, M. Paneque, D. Paoletti, R. Paredes, J.M. Pavletić, L. Peñil, P. Persic, M. Pihet, M. Prada Moroni, P.G. Instituto de Astrofísica de Canarias Dpto. de Astrofísica Universidad de La Laguna Tenerife La LagunaE-38200 Spain Università di Udine INFN Trieste UdineI-33100 Italy RomeI-00136 Italy ETH Zürich ZürichCH-8093 Switzerland Bellaterra BarcelonaE-08193 Spain The University of Tokyo Chiba Kashiwa277-8582 Japan Technische Universität Dortmund DortmundD-44221 Germany Zagreb10000 Croatia IPARCOS Institute EMFTEL Department Universidad Complutense de Madrid MadridE-28040 Spain Rio de Janeiro22290-180 Brazil Università di Padova INFN PadovaI-35131 Italy University of Lodz Faculty of Physics and Applied Informatics Department of Astrophysics Lodz90-236 Poland Università di Siena INFN Pisa SienaI-53100 Italy ZeuthenD-15738 Germany Max-Planck-Institut für Physik MünchenD-80805 Germany Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n Granada18008 Spain Università di Pisa INFN Pisa PisaI-56126 Italy Universitat de Barcelona ICCUB IEEC-UB BarcelonaE-08028 Spain Armenian MAGIC Group A. Alikhanyan National Science Laboratory Yerevan0036 Armenia Centro de Investigaciones Energéticas Medioambientales y Tecnológicas MadridE-28040 Spain INFN MAGIC Group INFN Sezione di Catania Dipartimento di Fisica e Astronomia University of Catania CataniaI-95123 Italy INFN MAGIC Group INFN Sezione di Torino Università degli Studi di Torino TorinoI-10125 Italy INFN MAGIC Group INFN Sezione di Bari Dipartimento Interateneo di Fisica Università e del Politecnico di Bari BariI-70125 Italy Croatian MAGIC Group University of Rijeka Department of Physics Rijeka51000 Croatia Universität Würzburg WürzburgD-97074 Germany Finnish MAGIC Group Finnish Centre for Astronomy with ESO University of Turku TurkuFI-20014 Finland Departament de Física CERES-IEEC Universitat Autònoma de Barcelona BellaterraE-08193 Spain Japanese MAGIC Group: Physics Program Graduate School of Advanced Science and Engineering Hiroshima Univers

Classical novae are cataclysmic binary star systems in which the matter of a companion star is accreted on a white dwarf (WD) [1, 2]. Accumulation of hydrogen in a layer eventually causes a thermonuclear explosion on the surface of the WD [3], brightening the WD to ∼ 105 solar luminosities and triggering ejection of the accumulated matter. They provide extreme conditions required to accelerate particles, electrons or protons, to high energies. Here we present the detection of gamma rays by the MAGIC telescopes from the 2021 outburst of RS Ophiuchi (RS Oph), a recurrent nova with a red giant (RG) companion, that allowed us, for the first time, to accurately characterize the emission from a nova in the 60 GeV to 250 GeV energy range. The theoretical interpretation of the combined FermiLAT and MAGIC data suggests that protons are accelerated to hundreds of GeV in the nova shock. Such protons should create bubbles of enhanced Cosmic Ray density, on the order of 10 pc, from the recurrent novae. Copyright © 2022, The Authors. All rights reserved.

关键词： Cosmology

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E3 – A user’s interface for quantifying total cost, diesel consumption, and emissions from bulldozers and its comparison to field data

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AIP Conference Proceedings 2017年第1期1887卷

作者： Apif M. Hajji Michael P. Lewis Aisyah Larasati 1Department of Civil Engineering Faculty of Engineering State University of Malang Malang Indonesia 2School of Civil and Environmental Engineering. Oklahoma State University USA 3Industrial Engineering Study Program Universitas Negeri Malang Indonesia

The use of bulldozer in construction projects determines a vast number of diesel consumption, emissions and the portion of total cost of the project. Construction equipment operators need a method that can be utilized to predict and quantify not only the cost, but also the diesel consumption and emissions of construction projects, particularly for bulldozer’s activities. The main purpose of this paper is to propose an E3, the predicting tool for the economic, energy, and environmental impact of the use of bulldozer. The tool was developed by using the productivity rate model of bulldozer to the US EPA’s NONROAD model. The results show that the bulldozer’s productivity model can be used as the platform for predicting the total cost and diesel consumption that will be required and the total expected emissions for the project.

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

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Nature 2024年第8003期627卷 347-357页

作者： Ken Suzuki Konstantinos Hatzikotoulas Lorraine Southam Henry J Taylor Xianyong Yin Kim M Lorenz Ravi Mandla Alicia Huerta-Chagoya Giorgio E M Melloni Stavroula Kanoni Nigel W Rayner Ozvan Bocher Ana Luiza Arruda Kyuto Sonehara Shinichi Namba Simon S K Lee Michael H Preuss Lauren E Petty Philip Schroeder Brett Vanderwerff Mart Kals Fiona Bragg Kuang Lin Xiuqing Guo Weihua Zhang Jie Yao Young Jin Kim Mariaelisa Graff Fumihiko Takeuchi Jana Nano Amel Lamri Masahiro Nakatochi Sanghoon Moon Robert A Scott James P Cook Jung-Jin Lee Ian Pan Daniel Taliun Esteban J Parra Jin-Fang Chai Lawrence F Bielak Yasuharu Tabara Yang Hai Gudmar Thorleifsson Niels Grarup Tamar Sofer Matthias Wuttke Chloé Sarnowski Christian Gieger Darryl Nousome Stella Trompet Soo-Heon Kwak Jirong Long Meng Sun Lin Tong Wei-Min Chen Suraj S Nongmaithem Raymond Noordam Victor J Y Lim Claudia H T Tam Yoonjung Yoonie Joo Chien-Hsiun Chen Laura M Raffield Bram Peter Prins Aude Nicolas Lisa R Yanek Guanjie Chen Jennifer A Brody Edmond Kabagambe Ping An Anny H Xiang Hyeok Sun Choi Brian E Cade Jingyi Tan K Alaine Broadaway Alice Williamson Zoha Kamali Jinrui Cui Manonanthini Thangam Linda S Adair Adebowale Adeyemo Carlos A Aguilar-Salinas Tarunveer S Ahluwalia Sonia S Anand Alain Bertoni Jette Bork-Jensen Ivan Brandslund Thomas A Buchanan Charles F Burant Adam S Butterworth Mickaël Canouil Juliana C N Chan Li-Ching Chang Miao-Li Chee Ji Chen Shyh-Huei Chen Yuan-Tsong Chen Zhengming Chen Lee-Ming Chuang Mary Cushman John Danesh Swapan K Das H Janaka de Silva George Dedoussis Latchezar Dimitrov Ayo P Doumatey Shufa Du Qing Duan Kai-Uwe Eckardt Leslie S Emery Daniel S Evans Michele K Evans Krista Fischer James S Floyd Ian Ford Oscar H Franco Timothy M Frayling Barry I Freedman Pauline Genter Hertzel C Gerstein Vilmantas Giedraitis Clicerio González-Villalpando Maria Elena González-Villalpando Penny Gordon-Larsen Myron Gross Lindsay A Guare Sophie Hackinger Liisa Hakaste Sohee Han Andrew T Hattersley Christian Herder Momoko Horikoshi Annie-Green Howard Willa Centre for Genetics and Genomics Versus Arthritis Centre for Musculoskeletal Research Division of Musculoskeletal and Dermatological Sciences University of Manchester Manchester UK. Department of Diabetes and Metabolic Diseases Graduate School of Medicine University of Tokyo Tokyo Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. konstantinos.hatzikotoulas@helmholtz-munich.de. Institute of Translational Genomics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany. Center for Precision Health Research National Human Genome Research Institute National Institutes of Health Bethesda MD USA. British Heart Foundation Cardiovascular Epidemiology Unit Department of Public Health and Primary Care University of Cambridge Cambridge UK. Heart and Lung Research Institute University of Cambridge Cambridge UK. Department of Epidemiology School of Public Health Nanjing Medical University Nanjing China. Department of Biostatistics and Center for Statistical Genetics University of Michigan Ann Arbor MI USA. Corporal Michael J. Crescenz VA Medical Center Philadelphia PA USA. Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Department of Genetics University of Pennsylvania Perelman School of Medicine Philadelphia PA USA. Programs in Metabolism and Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA. Diabetes Unit and Center for Genomic Medicine Massachusetts General Hospital Boston MA USA. TIMI Study Group Division of Cardiovascular Medicine Brigham and Women's Hospital Harvard Medical School Boston MA USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London L

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (P < 5 × 10) that map to 611 loci, of which 145 loci are, to our knowledge, previously unreported. We define eight non-overlapping clusters of T2D signals that are characterized by distinct profiles of cardiometabolic trait associations. These clusters are differentially enriched for cell-type-specific regions of open chromatin, including pancreatic islets, adipocytes, endothelial cells and enteroendocrine cells. We build cluster-specific partitioned polygenic scores in a further 279,552 individuals of diverse ancestry, including 30,288 cases of T2D, and test their association with T2D-related vascular outcomes. Cluster-specific partitioned polygenic scores are associated with coronary artery disease, peripheral artery disease and end-stage diabetic nephropathy across ancestry groups, highlighting the importance of obesity-related processes in the development of vascular outcomes. Our findings show the value of integrating multi-ancestry genome-wide association study data with single-cell epigenomics to disentangle the aetiological heterogeneity that drives the development and progression of T2D. This might offer a route to optimize global access to genetically informed diabetes care.

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