Deep learning has revolutionized medical imaging, offering advanced methods for accurate diagnosis and treatment planning. The BCLC staging system is crucial for staging Hepatocellular Carcinoma (HCC), a high-mortalit...
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ISBN:
(数字)9798350351552
ISBN:
(纸本)9798350351569
Deep learning has revolutionized medical imaging, offering advanced methods for accurate diagnosis and treatment planning. The BCLC staging system is crucial for staging Hepatocellular Carcinoma (HCC), a high-mortality cancer. An automated BCLC staging system could significantly enhance diagnosis and treatment planning efficiency. However, we found that BCLC staging, which is directly related to the size and number of liver tumors, aligns well with the principles of the Multiple Instance Learning (MIL) framework. To effectively achieve this, we proposed a new preprocessing technique called Masked Cropping and Padding(MCP), which addresses the variability in liver volumes and ensures consistent input sizes. This technique preserves the structural integrity of the liver, facilitating more effective learning. Furthermore, we introduced Re ViT, a novel hybrid model that integrates the local feature extraction capabilities of Convolutional Neural Networks (CNNs) with the global context modeling of Vision Transformers (ViTs). Re ViT leverages the strengths of both architectures within the MIL framework, enabling a robust and accurate approach for BCLC staging. We will further explore the trade-off between performance and interpretability by employing TopK Pooling strategies, as our model focuses on the most informative instances within each bag.
computational protein design has the potential to deliver novel molecular structures, binders, and catalysts for myriad applications. Recent neural graph-based models that use backbone coordinate-derived features show...
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Electric consumption prediction methods are investigated for many reasons such as decision-making related to energy efficiency as well as for anticipating demand in the energy market dynamics. The objective of the pre...
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Reactivity of OH and hydride species in oxide-catalyzed hydrogenation reactions has attracted great interest. Herein, we report a combined in situ spectroscopic characterization and density functional theory (DFT) cal...
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Defects in gastric progenitor cell differentiation are associated with various gastric disorders, including atrophic gastritis, intestinal metaplasia, and gastric cancer. However, the mechanisms underlying the multili...
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Defects in gastric progenitor cell differentiation are associated with various gastric disorders, including atrophic gastritis, intestinal metaplasia, and gastric cancer. However, the mechanisms underlying the multilineage differentiation of gastric progenitor cells during healthy homeostasis remain poorly understood. Here, using a single-cell RNA sequencing method, Quartz-Seq2, we analyzed the gene expression dynamics of progenitor cell differentiation toward pit cell, neck cell, and parietal cell lineages in healthy adult mouse corpus tissues. Enrichment analysis of pseudotime-dependent genes and a gastric organoid assay revealed that EGFR-ERK signaling promotes pit cell differentiation, whereas NF-κB signaling maintains gastric progenitor cells in an undifferentiated state. In addition, pharmacological inhibition of EGFR in vivo resulted in a decreased number of pit cells. Although activation of EGFR signaling in gastric progenitor cells has been suggested as one of the major inducers of gastric cancers, our findings unexpectedly identified that EGFR signaling exerts a differentiation-promoting function, not a mitogenic function, in normal gastric homeostasis.
This paper presents a comprehensive study on the critical role of efficient transportation systems in urban settings, particularly in developing countries. It underscores the socio-economic and environmental impacts o...
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This study presents a novel approach to human keypoint detection in low-resolution thermal images using transfer learning techniques. We introduce the first application of the Timed Up and Go (TUG) test in thermal ima...
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Immersive learning has gained significant attention with the rising trend of spatial computing, particularly in the after-pandemic era. Numerous research has explored the potential of immersive learning in higher educ...
Immersive learning has gained significant attention with the rising trend of spatial computing, particularly in the after-pandemic era. Numerous research has explored the potential of immersive learning in higher education, primarily on the educational sector. However, prior research has frequently focused too narrowly on the effects of technology and neglected to address the crucial element influencing successful immersive learning in higher education. This study seeks to pinpoint the crucial element contributing to the development of immersive learning experiences. The methodology uses a systematic literature review (SLR) from 2018 up to 2023 to investigate the critical factors of immersive Learning in Higher Education. From the 728 papers initially retrieved, 274 were considered potential candidates, and ultimately, 86 articles were selected based on their relevance to the research question. The results reveal that the critical factors include learning design, technology, immersion, engagement, interactivity, and usability. Academic interests will benefit from this SLR's consequences as institutions create models for designing suitable immersive learning, especially within the context of higher education.
The emergence of cloud computing technology has motivated a very high number of users in different organizations to access its services in running and delivering their various operations and services. However, this su...
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ISBN:
(数字)9798350358155
ISBN:
(纸本)9798350358162
The emergence of cloud computing technology has motivated a very high number of users in different organizations to access its services in running and delivering their various operations and services. However, this surge of cloud users has led to the problem of uneven load sharing among the cloud computing infrastructures. As a result, federated cloud infrastructure was initiated to provide more cloud computing resources to accommodate more cloud users’ requests and also to provide equal requests mapping with the available cloud resources. Nevertheless, the issue of unequal allocation of requests within the datacenter(s) that makes up the federated cloud environment still persists. This research work presents an intra-datacenter load balancing algorithm in a federated cloud environment named; the intra-balancer adapted throttled algorithm to evenly distribute requests in each datacenter that formulate the federated cloud infrastructures. The simulation of the intra-balancer was carried out in CloudAnalyst, the results of the implementation showed that the intra-balancer outperformed the Round-Robin and ESCE with 98.93ms and 2.26ms for the response and processing time respectively. The results assert that the intra-balancer algorithm provides a better load balancing solution in a federated cloud environment.
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