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检索条件"机构=Informatics and Data Science Program"
288 条 记 录,以下是151-160 订阅
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Pruritus and Its Association With Cancer and Mortality in Dermatomyositis and Polymyositis: A Nationwide Cohort Study in Taiwan From 2005 to 2022
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Dermatologic Therapy 2025年 第1期2025卷
作者: Der-Jr Huang Yu-Hsuan Joni Shao Yi-Hsien Shih Woan-Ruoh Lee Ling-Ya Huang Yu-Min Kuo Quoc Thao Trang Pham Hao-Jui Weng Department of Dermatology Taipei Medical University-Shuang Ho Hospital New Taipei City Taiwan shh.org.tw Graduate Institute of Biomedical Informatics College of Medical Science and Technology Taipei Medical University Taipei Taiwan tmu.edu.tw Clinical Big Data Research Center Taipei Medical University Hospital Taipei Taiwan tmuh.org.tw Health Data Analytics and Statistics Center Office of Data Science Taipei Medical University Taipei Taiwan tmu.edu.tw Department of Dermatology School of Medicine College of Medicine Taipei Medical University Taipei Taiwan tmu.edu.tw Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei Taiwan tmu.edu.tw Division of Allergy Immunology and Rheumatology Department of Internal Medicine National Taiwan University Hospital and National Taiwan University Taipei Taiwan ntu.edu.tw Graduate Institute of Clinical Medicine College of Medicine National Taiwan University Taipei Taiwan ntu.edu.tw International Ph.D. Program in Cell Therapy and Regenerative Medicine College of Medicine Taipei Medical University Taipei Taiwan tmu.edu.tw Department of Dermatology Faculty of Medicine University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam hcmut.edu.vn Graduate Institute of Clinical Medicine College of Medicine Taipei Medical University Taipei Taiwan medcol.mw
Background: Pruritus is the most common initial symptom reported by patients with dermatomyositis (DM) and polymyositis (PM). However, there is limited data regarding the impact of pruritus on cancer and mortality in ... 详细信息
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A robust multiplex-DIA workflow profiles protein turnover regulations associated with cisplatin resistance and aneuploidy
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Nature communications 2025年 第1期16卷 5034页
作者: Barbora Salovska Wenxue Li Oliver M Bernhardt Pierre-Luc Germain Qinyue Wang Tejas Gandhi Lukas Reiter Yansheng Liu Department of Pharmacology Yale University School of Medicine New Haven CT USA. Cancer Biology Institute Yale University School of Medicine West Haven CT USA. Biognosys AG Zurich-Schlieren Switzerland. Institute for Neuroscience Department of Health Sciences and Technology ETH Zurich Zurich Switzerland. Master Program of Public Health Department of Chronic Disease Epidemiology Yale School of Public Health New Haven CT USA. Department of Pharmacology Yale University School of Medicine New Haven CT USA. yansheng.liu@yale.edu. Cancer Biology Institute Yale University School of Medicine West Haven CT USA. yansheng.liu@yale.edu. Department of Biomedical Informatics & Data Science Yale University School of Medicine New Haven CT USA. yansheng.liu@yale.edu.
Quantifying protein turnover is fundamental to understanding cellular processes and advancing drug discovery. Multiplex-DIA mass spectrometry (MS), combined with dynamic SILAC labeling (pulse-SILAC, or pSILAC) reliabl...
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Advances of machine learning in molecular modeling and simulation
arXiv
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arXiv 2019年
作者: Haghighatlari, Mojtaba Hachmann, Johannes Department of Chemical and Biological Engineering University at Buffalo State University of New York BuffaloNY14260 United States Computational and Data-Enabled Science and Engineering Graduate Program University at Buffalo State University of New York BuffaloNY14260 United States New York State Center of Excellence in Materials Informatics BuffaloNY14203 United States
In this review, we highlight recent developments in the application of machine learning for molecular modeling and simulation. After giving a brief overview of the foundations, components, and workflow of a typical su... 详细信息
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Reconciling emergences: An information-theoretic approach to identify causal emergence in multivariate data
arXiv
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arXiv 2020年
作者: Rosas, Fernando E. Mediano, Pedro A.M. Jensen, Henrik J. Seth, Anil K. Barrett, Adam B. Carhart-Harris, Robin L. Bor, Daniel Center for Psychedelic Research Department of Brain Science Imperial College London SW7 2DD United Kingdom Data Science Institute Imperial College London LondonSW7 2AZ United Kingdom Center for Complexity Science Imperial College London LondonSW7 2AZ United Kingdom Department of Psychology University of Cambridge CambridgeCB2 3EB United Kingdom Department of Mathematics Imperial College London LondonSW7 2AZ United Kingdom Institute of Innovative Research Tokyo Institute of Technology Yokohama226-8502 Japan Sackler Center for Consciousness Science Department of Informatics University of Sussex BrightonBN1 9RH United Kingdom CIFAR Azrieli Program on Brain Mind and Consciousness TorontoM5G 1M1 Canada Data Intensive Science Centre Department of Physics and Astronomy University of Sussex BrightonBN1 9QH United Kingdom Center for Psychedelic Research Department of Brain Science Imperial College London LondonSW7 2DD United Kingdom
The broad concept of emergence is instrumental in various of the most challenging open scientific questions - yet, few quantitative theories of what constitutes emergent phenomena have been proposed. This article intr... 详细信息
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A Causal Roadmap for Generating High-Quality Real-World Evidence
arXiv
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arXiv 2023年
作者: Dang, Lauren E. Gruber, Susan Lee, Hana Dahabreh, Issa Stuart, Elizabeth A. Williamson, Brian D. Wyss, Richard Díaz, Iván Ghosh, Debashis Kıcıman, Emre Alemayehu, Demissie Hoffman, Katherine L. Vossen, Carla Y. Huml, Raymond A. Ravn, Henrik Kvist, Kajsa Pratley, Richard Shih, Mei-Chiung Pennello, Gene Martin, David Waddy, Salina P. Barr, Charles E. Akacha, Mouna Buse, John B. van der Laan, Mark Petersen, Maya Department of Biostatistics University of California BerkeleyCA United States TL Revolution CambridgeMA United States Office of Biostatistics Office of Translational Sciences Center for Drug Evaluation and Research U.S. Food and Drug Administration Silver SpringMD United States Department of Epidemiology Harvard T.H. Chan School of Public Health BostonMA United States Department of Mental Health Johns Hopkins Bloomberg School of Public Health BaltimoreMD United States Biostatistics Division Kaiser Permanente Washington Health Research Institute SeattleWA United States Division of Pharmacoepidemiology and Pharmacoeconomics Brigham and Women’s Hospital Harvard Medical School BostonMA United States Division of Biostatistics Department of Population Health New York University Grossman School of Medicine New YorkNY United States Department of Biostatistics and Informatics Colorado School of Public Health University of Colorado Anschutz Medical Campus AuroraCO United States Microsoft Research RedmondWA United States Global Biometrics and Data Management Pfizer Inc. New YorkNY United States Department of Epidemiology Mailman School of Public Health Columbia University New YorkNY United States Syneos Health Clinical Solutions Amsterdam Netherlands Syneos Health Clinical Solutions MorrisvilleNC United States Novo Nordisk Søborg Denmark AdventHealth Translational Research Institute OrlandoFL United States Cooperative Studies Program Coordinating Center VA Palo Alto Health Care System Palo AltoCA United States Department of Biomedical Data Science Stanford University StanfordCA United States Division of Imaging Diagnostics and Software Reliability Office of Science and Engineering Laboratories Center for Devices and Radiological Health U.S. Food and Drug Administration Silver SpringMD United States Global Real World Evidence Group Moderna CambridgeMA United States National Center for Advancing Translational Sciences BethesdaMD United States G
Increasing emphasis on the use of real-world evidence (RWE) to support clinical policy and regulatory decision-making has led to a proliferation of guidance, advice, and frameworks from regulatory agencies, academia, ... 详细信息
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Declaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas
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Revista Española de Cardiología (English Edition) 2021年 第9期74卷 790-799页
作者: Matthew J. Page Joanne E. McKenzie Patrick M. Bossuyt Isabelle Boutron Tammy C. Hoffmann Cynthia D. Mulrow Larissa Shamseer Jennifer M. Tetzlaff Elie A. Akl Sue E. Brennan Roger Chou Julie Glanville Jeremy M. Grimshaw Asbjørn Hróbjartsson Manoj M. Lalu Tianjing Li Elizabeth W. Loder Evan Mayo-Wilson David Moher School of Public Health and Preventive Medicine Monash University Melbourne Australia Department of Clinical Epidemiology Biostatistics and Bioinformatics Amsterdam University Medical Centres University of Amsterdam Amsterdam Países Bajos Université de Paris Centre of Epidemiology and Statistics (CRESS) Inserm F 75004 Paris Francia Institute for Evidence-Based Healthcare Faculty of Health Sciences and Medicine Bond University Gold Coast Australia University of Texas Health Science Center at San Antonio San Antonio Texas Estados Unidos Annals of Internal Medicine Knowledge Translation Program Li Ka Shing Knowledge Institute Toronto Canadá School of Epidemiology and Public Health Faculty of Medicine University of Ottawa Ottawa Canada Evidence Partners Ottawa Canadá Clinical Research Institute American University of Beirut Beirut Líbano Department of Health Research Methods Evidence and Impact McMaster University Hamilton Ontario Canadá Department of Medical Informatics and Clinical Epidemiology Oregon Health & Science University Portland Oregón Estados Unidos York Health Economics Consortium (YHEC Ltd) University of York York Reino Unido Clinical Epidemiology Program Ottawa Hospital Research Institute Ottawa Canadá School of Epidemiology and Public Health University of Ottawa Ottawa Canadá Department of Medicine University of Ottawa Ottawa Canadá Centre for Evidence-Based Medicine Odense Odense University Hospital Odense Dinamarca Department of Clinical Research University of Southern Denmark Odense Dinamarca Open Patient data Explorative Network Odense University Hospital Odense Dinamarca Department of Anesthesiology and Pain Medicine The Ottawa Hospital Ottawa Canadá Clinical Epidemiology Program Blueprint Translational Research Group Ottawa Hospital Research Institute Ottawa Canadá Regenerative Medicine Program Ottawa Hospital Research Institute Ottawa Canadá Department of Ophthalmology School of Medicine University of Colorado Denver Den
La declaración PRISMA ( Preferred Reporting Items for Systematic reviews and Meta-Analyses ), publicada en 2009, se diseñó para ayudar a los autores de revisiones sistemáticas a documentar de maner... 详细信息
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Author Correction: Developmental exposure of California mice to endocrine disrupting chemicals and potential effects on the microbiome-gut-brain axis at adulthood
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Scientific reports 2020年 第1期10卷 12524页
作者: Sarabjit Kaur Saurav J Sarma Brittney L Marshall Yang Liu Jessica A Kinkade Madison M Bellamy Jiude Mao William G Helferich A Katrin Schenk Nathan J Bivens Zhentian Lei Lloyd W Sumner John A Bowden Jeremy P Koelmel Trupti Joshi Cheryl S Rosenfeld Christopher S Bond Life Sciences Center University of Missouri Columbia MO 65211 USA. Biomedical Sciences University of Missouri Columbia MO 65211 USA. MU Metabolomics Center University of Missouri Columbia MO 65211 USA. MU Institute of Data Science and Informatics University of Missouri Columbia MO 65211 USA. Food Science and Human Nutrition University of Illinois Urbana IL 61801 USA. Physics Randolph College Lynchburg VA 24503 USA. DNA Core Facility University of Missouri Columbia MO 65211 USA. Department of Biochemistry University of Missouri Columbia MO 65211 USA. Department of Physiological Sciences College of Veterinary Medicine University of Florida Gainesville FL 32610 USA. Center for Environmental and Human Toxicology College of Veterinary Medicine University of Florida Gainesville FL 32610 USA. Environmental Health Sciences Yale University New Haven CT 06510 USA. Department of Health Management and Informatics School of Medicine University of Missouri Columbia MO 65211 USA. Christopher S Bond Life Sciences Center University of Missouri Columbia MO 65211 USA. rosenfeldc@missouri.edu. Biomedical Sciences University of Missouri Columbia MO 65211 USA. rosenfeldc@missouri.edu. MU Institute of Data Science and Informatics University of Missouri Columbia MO 65211 USA. rosenfeldc@missouri.edu. Thompson Center for Autism and Neurobehavioral Disorders University of Missouri Columbia MO 65211 USA. rosenfeldc@missouri.edu. Genetics Area Program University of Missouri Columbia MO 65211 USA. rosenfeldc@missouri.edu.
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Ten quick tips for deep learning in biology
arXiv
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arXiv 2021年
作者: Lee, Benjamin D. Gitter, Anthony Greene, Casey S. Raschka, Sebastian Maguire, Finlay Titus, Alexander J. Kessler, Michael D. Lee, Alexandra J. Chevrette, Marc G. Stewart, Paul Allen Britto-Borges, Thiago Cofer, Evan M. Yu, Kun-Hsing Carmona, Juan Jose Fertig, Elana J. Kalinin, Alexandr A. Signal, Beth Lengerich, Benjamin J. Triche, Timothy J. Boca, Simina M. In-Q-Tel Labs School of Engineering and Applied Sciences Harvard University Department of Genetics Harvard Medical School United States Department of Biostatistics and Medical Informatics University of Wisconsin-Madison MadisonWI United States Morgridge Institute for Research MadisonWI United States Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Biochemistry and Molecular Genetics University of Colorado School of Medicine AuroraCO United States Center for Health AI University of Colorado School of Medicine AuroraCO United States Department of Statistics University of Wisconsin Madison United States Faculty of Computer Science Dalhousie University Canada University of New Hampshire Bioeconomy.XYZ United States Department of Oncology Johns Hopkins University United States Institute for Genome Sciences University of Maryland School of Medicine United States Genomics and Computational Biology Graduate Program University of Pennsylvania United States Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania United States Wisconsin Institute for Discovery Department of Plant Pathology University of Wisconsin-Madison United States Department of Biostatistics and Bioinformatics Moffitt Cancer Center TampaFL United States Section of Bioinformatics and Systems Cardiology Klaus Tschira Institute for Integrative Computational Cardiology University Hospital Heidelberg Germany University Hospital Heidelberg Germany Lewis-Sigler Institute for Integrative Genomics Princeton University PrincetonNJ United States Graduate Program in Quantitative and Computational Biology Princeton University PrincetonNJ United States Department of Biomedical Informatics Harvard Medical School United States Department of Pathology Brigham and Women's Hospital United States Philips Healthcare CambridgeMA United States Philips Research
Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and us... 详细信息
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Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
Research Square
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Research Square 2021年
作者: Zhang, Martin Jinye Hou, Kangcheng Pasaniuc, Bogdan Price, Alkes L. Dey, Kushal K. Jagadeesh, Karthik A. Weinand, Kathryn Sakaue, Saori Taychameekiatchai, Aris Rao, Poorvi Pisco, Angela Oliveira Zou, James Wang, Bruce Gandal, Michael Raychaudhuri, Soumya Harvard University United States Osaka University Japan Department of Epidemiology Harvard T.H. Chan School of Public Health BostonMA United States Program in Medical and Population Genetics Broad Institute of MIT and Harvard CambridgeMA United States Bioinformatics Interdepartmental Program University of California Los Angeles Los AngelesCA United States Department of Pathology and Laboratory Medicine David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Department of Computational Medicine David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Center for Data Sciences Brigham and Women’s Hospital BostonMA United States Division of Genetics Department of Medicine Brigham and Women’s Hospital Harvard Medical School BostonMA United States Division of Rheumatology Inflammation and Immunity Department of Medicine Brigham and Women’s Hospital Harvard Medical School BostonMA United States Department of Biomedical Informatics Harvard Medical School BostonMA United States Department of Medicine and Liver Center University of California San Francisco San FranciscoCA United States Developmental and Stem Cell Biology Graduate Program University of California San Francisco San FranciscoCA United States Chan Zuckerberg Biohub San FranciscoCA United States Department of Electrical Engineering Stanford University Palo AltoCA United States Department of Biomedical Data Science Stanford University Palo AltoCA United States Department of Psychiatry David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Program in Neurobehavioral Genetics Semel Institute David Geffen School of Medicine University of California Los Angeles Los AngelesCA United States Versus Arthritis Centre for Genetics and Genomic
Gene expression at the individual cell-level resolution, as quantified by single-cell RNA-sequencing (scRNA-seq), can provide unique insights into the pathology and cellular origin of diseases and complex traits. Here... 详细信息
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Mapping of human monoclonal antibody responses to XBB.1.5 COVID-19 monovalent vaccines: a B cell analysis
The Lancet. Microbe
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The Lancet. Microbe 2025年 101103页
作者: Raianna F Fantin Jordan J Clark Hallie Cohn Deepika Jaiswal Bailey Bozarth Vishal Rao Alesandro Civljak Igor Lobo Jessica R Nardulli Komal Srivastava Jeremy S Yong Robert Andreata-Santos Kaitlyn Bushfield Edward S Lee Gagandeep Singh Steven H Kleinstein Florian Krammer Viviana Simon Goran Bajic Camila H Coelho Department of Microbiology Icahn School of Medicine at Mount Sinai New York NY USA Center for Vaccine Research and Pandemic Preparedness Icahn School of Medicine at Mount Sinai New York NY USA. Department of Microbiology Icahn School of Medicine at Mount Sinai New York NY USA. Center for Vaccine Research and Pandemic Preparedness Icahn School of Medicine at Mount Sinai New York NY USA Graduate School of Biomedical Sciences Icahn School of Medicine at Mount Sinai New York NY USA. Retrovirology Laboratory Department of Microbiology Immunology and Parasitology Paulista School of Medicine Federal University of São Paulo São Paulo Brazil. Department of Laboratory Medicine Yale School of Medicine New Haven CT USA Department of Pathology Yale School of Medicine New Haven CT USA. Department of Pathology Yale School of Medicine New Haven CT USA Program in Computational Biology and Biomedical Informatics Yale University New Haven CT USA Department of Immunobiology Yale School of Medicine New Haven CT USA Department of Biomedical Informatics and Data Science Yale School of Medicine New Haven CT USA. Department of Pathology Molecular and Cell-Based Medicine Icahn School of Medicine at Mount Sinai New York NY USA Ignaz Semmelweis Institute Interuniversity Institute for Infection Research Medical University of Vienna Vienna Austria. The Global Health and Emerging Pathogens Institute Icahn School of Medicine at Mount Sinai New York NY USA Division of Infectious Diseases Department of Medicine Icahn School of Medicine at Mount Sinai New York NY USA. Program in Computational Biology and Biomedical Informatics Yale University New Haven CT USA. Electronic address: goran.bajic@mssm.edu. Precision Immunology Institute Icahn School of Medicine at Mount Sinai New York NY USA. Electronic address: camila.coelho@mssm.edu.
BACKGROUND:The rapid emergence of highly transmissible and immune-evasive SARS-CoV-2 variants has required the reformulation of COVID-19 vaccines to target these evolving threats. Although previous infections and boos...
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