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CHEMISTRY & BIOLOGY 2010年第4期17卷 311-312页

作者： McCarthy, Alice Main Text “In June 2003 the scientific and medical communities at MIT Harvard University and its affiliated hospitals and the Whitehead Institute banded together as collaborating partners to form the Eli and Edythe L. Broad Institute based in Cambridge MA. The Broad Institute established with initial funding from a $100 million philanthropic donation from the Los Angeles-based Broad family was primarily viewed as a marriage between the Whitehead Institute's Center for Genome Research (WICGR) and the Harvard Institute of Chemistry and Cell Biology (ICCB). Eli Broad founder and chairman of AIG SunAmerica Inc. explained “the purpose of the Broad Institute is to create a new type of research institute to build on the accomplishments of the human genome project and to move to clinical applications to both prevent and cure diseases.” Every Thursday morning we meet with perhaps 20 faculty members and 100 other researchers to discuss what we're all doing and should be doing next. -David Altschuler This paragraph was written five years ago when the Broad Institute was in its very earliest days as a life science research community (McCarthy 2005). Since that time “the Broad” as it's known has kept true to Eli Broad's vision having attracted a talented group of researchers faculty trainees and professional staff. This 1600 person research community known internally as “Broadies” includes faculty staff and students from throughout the MIT and Harvard biomedical research communities and beyond with collaborations spanning over a hundred private and public institutions in more than 40 countries worldwide. “What is special about the Broad is that we have people from Harvard MIT and the Harvard hospitals come together and work on problems of shared interest that could not be solved in their own individuals labs” explains David Altshuler M.D. Ph.D. Deputy Director and one of the Broad's six core faculty members. “These problems require expertise beyond any one principal investigator and in

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Design and acceptance testing during reconstruction of Terminal Apron taxi lanes at Hartsfield Jackson Atlanta International Airport

Design and acceptance testing during reconstruction of Termi...

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2006 Airfield and Highway Pavement Specialty Conference

作者： Seiler, Wayne Gambino, Thomas Nazarian, Soheil Hayes, Frank Watkins, Quintin Pavements Inc. Mahomet IL 61853 United States Prime Engineering Inc. Atlanta GA 30318 United States Center for Transportation Infrastructure Systems Univ. of Texas El Paso TX 79968 United States Hartsfield-Jackson Development Program Atlanta GA 30337 United States Dept. of Aviation Hartsfield-Jackson Atlanta Intl. Airport Atlanta GA 30337 United States

ISBN: (纸本)0784408386

This project includes the reconstruction of three taxi lanes within the Terminal Aprons at Hartsfield Jackson Atlanta International Airport (HJAIA). The first taxi lane was located adjacent to 15 gates at the T Concourse, the second taxi lane was adjacent to 17 gates on the west side on Concourse A, and the third taxi lane was adjacent to nine gates on the east side of Concourse B, as shown in Figure 1. Several pavement design issues were addressed during the reconstruction of these jointed plain concrete pavement (JPCP) sections, including joint spacing, joint integration with the remaining JPCP sections, improvements to existing subsurface drainage systems, and the required load carrying capacity for several gates that support widebody aircraft. A detailed construction phasing plan was also developed as part of the design. This paper also addresses the success of the accelerated construction that was required during each phase. The results from laboratory testing for flexural strength, as required by the FAA, were compared to additional nondestructive seismic and maturity meter tests to determine when the gates could be opened to traffic.

关键词： Airport runways

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Spectroscopic and SAXS studies of heteropoly acid-doped 3M perfluorinated sulfonic acid polymer membranes

Spectroscopic and SAXS studies of heteropoly acid-doped 3M p...

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208th Meeting of the Electrochemical Society

作者： Meng, Fanqin Dec, Steven F. Willimason, Don Frey, Matthew H. Hamrock, Steven J. Turner, John A. Herring, Andrew M. Departments of Chemical Engineering Colorado School of Mines Golden CO 80401 United States Departments of Chemistry and Geochemistry Colorado School of Mines Golden CO 80401 United States Departments of Physics Colorado School of Mines Golden CO 80401 United States 3M Fuel Cell Components Program 3M Center St Paul MN 55144 United States 3M Corporate Research Material Laboratory 3M Center St Paul MN 55144 United States Hydrogen and Electricity Systems and Infrastructure Group National Renewable Energy Laboratory Golden CO 80401 United States

ISBN: (纸本)1566774969

3M PFSA ionomer membranes were doped with heteropolyacids (HPA) and the ionomer/HPA interaction characterized by attenuated total reflection FTIR, pulse field gradient spin echo NMR and small-angle X-ray scattering. The HPA doping was achieved by casting a solution containing both components. Three Keggin-type HPAs were used in this work: 12-phosphotungstic acid, 12-silicotungstic acid, and 12-zincotungstic acid, at doping concentrations of 1 and 5 wt %, respectively. FTIR spectra of the composite membranes clearly show the presence of the HPA and evidence for different interactions under different hydration states. Proton diffusion coefficients were determined by PFGSE NMR under dry and 100 % RH from ambient to 130°C. SAXS patterns of the control PFSA and the HPA-doped PFSA membranes were recorded under dry and wet conditions. Scattering behaviour for different samples and conditions are remarkably different, consistent with the incorporation of HPA and the swelling of ionomer clusters under hydration. copyright The Electrochemical Society.

关键词： Ion exchange membranes

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Generative representations in structural engineering

Generative representations in structural engineering

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2005 ASCE International Conference on Computing in Civil engineering

作者： Kicinger, Rafal Arciszewski, Tomasz De Jong, Kenneth Civil Environmental and Infrastructure Engineering Department Critical Infrastructure Protection Program George Mason University 4400 University Drive Fairfax VA 22030 Civil Environmental and Infrastructure Engineering Department George Mason University MS 4A6 4400 University Drive Fairfax VA 22030 Computer Science Department George Mason University MS 4A5 4400 University Drive Fairfax VA 22030

ISBN: (纸本)0784407940

This paper proposes a new approach to representing structural system inspired by various models of complex systems. Several types of generative representations of steel structural systems are provided and empirically investigated. These representations utilize various kinds of cellular automata to generate design concepts of steel structures in tall buildings. In the paper, a brief overview of the state-of-the-art in cellular automata and generative design is presented. Next, several types of generative representations of steel structural systems in tall buildings are described. The paper also reports the results of several design experiments. They have shown that generative representations produce novel structural shaping patterns which are qualitatively different than the patterns obtained using traditionally used parameterized representations. They also significantly improve the performance of evolutionary algorithms optimizing the structural systems. Finally, research conclusions are presented and most promising paths of future research are discussed.

关键词： Structural design

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Balanced Scorecard-Based Performance Measurement for Rural infrastructure Development of Thai Sub-District Local Government

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Asia-Pacific Journal of Rural Development 2005年第1期15卷 21 - 39页

作者： S. Posayanant C. Charoenngam Authors are Doctoral student and Associate Professor respectively of Construction Engineering and Infrastructure Management Program School of Civil Engineering Asian Institute of Technology Thailand. E-mail: ；

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On the design for a versatile imaging and hard x-ray beamline at the australian synchrotron: Implementation of in-line phase-contrast imaging 8

On the design for a versatile imaging and hard x-ray beamlin...

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8th International Conference on Synchrotron Radiation Instrumentation

作者： Wilkins, S.W. Lewis, R.A. Nesterets, Y. Garrett, R.F. Mayo, S.C. Nugent, K.A. Parry, D.J. Siu, K.K.-W. Stevenson, A.W. CSIRO Manufacturing and Infrastructure Technology PB33 Clayton Sth VIC3169 Australia School of Physics and Materials Engineering Monash University ClaytonVIC3168 Australia Australian Synchrotron Research Program C/o ANSTO PMB 1 MenaiNSW2234 Australia School of Physics University of Melbourne VIC3010 Australia

We outline key design features for a versatile imaging and hard X-ray beamline for operation at the Australian Synchrotron. Special attention is paid to the implementation of in-line phase-contrast imaging using both ...

ISBN: (纸本)0735401799

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On The Design For A Versatile Imaging And Hard X‐ray Beamline At the Australian Synchrotron: Implementation of In‐Line Phase‐Contrast Imaging

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AIP Conference Proceedings 2004年第1期705卷 380-383页

作者： S. W. Wilkins R. A. Lewis Y. Nesterets R. F. Garrett S. C. Mayo K. A. Nugent D. J. Parry K. K.‐W. Siu A. W. Stevenson ¶CSIRO Manufacturing and Infrastructure Technology PB33 Clayton Sth Vic 3169 Australia §School of Physics & Materials Engineering Monash University Clayton Vic 3168 Australia *Australian Synchrotron Research Program c/o ANSTO PMB 1 Menai NSW 2234 Australia **School of Physics University of Melbourne Vic 3010 Australia

We outline key design features for a versatile imaging and hard X‐ray beamline for operation at the Australian Synchrotron. Special attention is paid to the implementation of in‐line phase‐contrast imaging using bo...

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STRENGTH PRORERTIES OF MMA MODIFIED POLYMER MORTAR

STRENGTH PRORERTIES OF MMA MODIFIED POLYMER MORTAR

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第五届水泥与混凝土国际会议

作者： Joo Myung-ki Yeon Kyu-seok Regional Infrastructure Engineering Program Kangwon National University Chuncheon 200-701 Korea Regional Infrastructure Engineering Program Kangwon National University Chuncheon 200-701 Korea

MMA modified polymer mortar (MMPM), in which MMA was added to the unsaturated polyester resin, was developed for improving the development of early-age strength and the adhesive strength, of the existent polymer mortar using the polyester resin. To do this,MMPM was produced by mixing the polyester resin and the MMA monomer with the various weight ratios of 9:1,4:1,2. 5:1, 1. 5:1,1:0,1:1, and then its compressive and flexural strengths were tested. The early-age strength developments for the compressive and flexural strengths of the MMPM were turned out to be better than that of polyester resin mortar. Especially, when the content of MMA was in the range of 40%, the early-age strength development was predominant:strength at 3(6) hour showed about 60 (80)% of strength at 7 day. The flexural adhesive strength of MMPM was larger than that of polyester resin mortar. The results of experiment showed that the increasing effects of early-age strength development and adhesive strengths were apparently modified by mixing the MMA.

关键词： MMA modified polymer mortars early-age strength polyester resin mortar strength properties

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A parametric review of the built environment sustainability literature

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International Journal of Environmental Technology and Management 2002年第1-3期2卷 54-93页

作者： Pearce, Annie R. Vanegas, Jorge A. Sustainable Facilities and Infrastructure Program Georgia Tech. Research Institute Atlanta GA 30332-0837 United States Construction Engineering and Management Program School of Civil and Environmental Engineering Georgia Institute of Technology Atlanta GA 30332-0355 United States

The literature on built environment sustainability has grown dramatically in the past 10 years. Despite the proliferation of literature, there is still no consensus on how comprehensively and uniformly to define the concept of sustainability as it pertains to the built environment, nor is there consensus on what aspects of the built environment should be considered in evaluating the sustainability of a built facility. This paper, through an evaluation of selected sources from the sustainability literature, takes a first step in systematically identifying what parameters of both the built environment and the concept of sustainability are emphasised in the existing literature on the topic. The outcome is a set of parameters that can be used in future research to begin uniformly and comprehensively to define sustainability as it applies to built facilities, using techniques such as concept mapping, content analysis, dendograms, and other established research methods. Copyright © 2002 Inderscience Enterprises Ltd.

关键词： Sustainable development

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Defining sustainability for built environment systems: An operational framework

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International Journal of Environmental Technology and Management 2002年第1-3期2卷 94-113页

One of the ongoing challenges in the quest to make our built environment more sustainable is defining what sustainability means in terms understandable to and measurable by built environment decision makers. This paper illustrates one approach to developing a comprehensive and exhaustive definition of sustainability for the built environment: deriving domain-specific variables from fundamental principles and constraints that govern how earth systems work. The paper uses the concept of systems to define characteristics and critical constraints of both the earth as a whole and built facilities in particular. These constraints provide a basis for identifying conditions which must be met in order for a built facility system to be sustainable. The contribution of the paper is a decision space based on required sustainability conditions that can be used to evaluate facility alternatives in terms of their relative sustainability. Copyright © 2002 Inderscience Enterprises Ltd.

关键词： Sustainable development

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