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In Vitro Comparative Effect of Three Novel Borate Bioglasses on the Behaviors of Osteoblastic MC3T3-E1 Cells

Journal of Materials Science & technology 2014年第10期30卷 979-983页

作者： Xiaojuan Wei Tingfei Xi Yufeng Zheng Changqing Zhang Wenhai Huang Academy for Advanced Interdisplinary Studies Peking University College of Engineering Peking University Department of Orthopaedics Shanghai Sixth People's HospitalShanghai Jiaotong University Institute of Bio-engineering and Information Technology Materials School of Materials Science and EngineeringTongji University

Most related investigations focused on the effects of borate glass on cell proliferation/biocompatibility in vitro or bone repair in vivo; however, very few researches were carried out on other cell behaviors. Three novel borate bioglasses were designed as scaffolds for bone regeneration in this wok. Comparative effects of three bioglasses on the behaviors of osteoblastic MC3T3-E1 cells were evaluated. Excellent cytocompatibility of these novel borate bioglasses were approved in this work. Meanwhile, the promotion on cell proliferation, protein secretion and migration with minor cell apoptosis were also discussed in details, which contributed to the potential clinical application as a new biomaterial for orthopedics.

关键词： Comparative study Borate bioglass Osteoblastic cells Cell behavior In vitro

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IoT Implementation at Global Enterprises for Progressive Human Resource Practices 1

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1st International Conference on Mathematical Modeling and Computational Science, ICMMCS 2020

作者： Moyeenudin, H.M. Anandan, R. School of Hotel & Catering Management Vels Institute of Science Technology and Advanced Studies Pallavaram Chennai India Department of Computer Science & Engineering Vels Institute of Science Technology and Advanced Studies Pallavaram Chennai India

ISBN: (数字)9789813343894

ISBN: (纸本)9789813343887

The human resource division has skillfully improved to identify the employee performance to meet the employer’s commitment through Internet of things (IoT) in advanced multinational establishments, which encounters various jobs at the working environment. The majority of multinational companies is focused on identifying the right tools to improve their recruitment and training processes that deals with the organizational culture, commitment of employee, and overseeing the performance of an employee by IoT. To locate the specific aptitudes of individuals regarding the company’s policies, rules and regulation, the human resource management (HRM) recruits employee using varied channels with the aid of IoT, and the virtual platforms support the HRM for recruitment and training. This paper is focused on the implementation of IoT in human resource management for effective recruitment and training process. Secondly, it highlights the purpose and quantity-wise usage for human resource (HR) practices to determine the attendance, feedbacks, appraisals, and performance of an employee. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

关键词： Internet of things

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Efficient Centralized Cooperative Spectrum Sensing Techniques for Cognitive Networks

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Computer Systems Science & engineering 2023年第1期44卷 55-65页

作者： P.Gnanasivam G.T.Bharathy V.Rajendran T.Tamilselvi Department of Electronics and Communication Engineering Jerusalem College of EngineeringPallikaranaiChennai600100Tamil NaduIndia Department of Electronics and Communication Engineering Vels Institute of ScienceTechnology&Advanced StudiesPallavaramChennai600117Tamil NaduIndia

Wireless Communication is a system for communicating information from one point to other,without utilizing any connections like wire,cable,or other physical *** Radio(CR)based systems and networks are a revolutionary new perception in wireless *** sensing is a vital task of CR to avert destructive intrusion with licensed primary or main users and discover the accessible spectrum for the efficient utilization of the *** Cooperative Spectrum Sensing(CSS)is a kind of spectrum *** of the test metrics designed till now for sensing the spectrum is produced by using the Sample Covariance Matrix(SCM)of the received *** of the methods that use the SCM for the process of detection are Pietra-Ricci Index Detector(PRIDe),Hadamard Ratio(HR)detector,Gini Index Detector(GID),*** paper presents the simulation and comparative perfor-mance analysis of PRIDe with various other detectors like GID,HR,Arithmetic to Geometric Mean(AGM),Volume-based Detector number 1(VD1),Maximum-to-Minimum Eigenvalue Detection(MMED),and Generalized Likelihood Ratio Test(GLRT)using the MATLAB *** PRIDe provides better performance in the presence of variations in the power of the signal and the noise power with less computational complexity.

关键词： Cohnitive radio network collaborative spectrum sensing sample covariance matrix pietra-ricci index detector cooperative spectrum sensing generalized likelihood ratio test maximum-to-minimum eigenvalue detection volume-based detector number

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A palette of bridged bicycle-strengthened fluorophores

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Nature Methods 2025年 1-12页

作者： Zhang, Junwei Zhang, Kecheng Wang, Kui Wang, Bo Zhu, Siyan Qian, Hongping Ma, Yumiao Zhang, Mengling Liu, Tianyan Chen, Peng Shen, Yuan Fu, Yunzhe Fang, Shilin Zhang, Xinxin Zou, Peng Deng, Wulan Mu, Yu Chen, Zhixing College of Future Technology Institute of Molecular Medicine National Biomedical Imaging Center Beijing Key Laboratory of Cardiometabolic Molecular Medicine State Key Laboratory of Membrane Biology Peking University Beijing China Institute of Neuroscience State Key Laboratory of Neuroscience Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences Shanghai China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary Studies Peking University Beijing China Biomedical Pioneering Innovation Center (BIOPIC) Peking University Beijing China College of Chemistry and Molecular Engineering Synthetic and Functional Biomolecules Center Beijing National Laboratory for Molecular Sciences Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education PKU-IDG/McGovern Institute for Brain Research Peking University Beijing China College of Biological Sciences and Biotechnology Beijing Forestry University Beijing China BSJ Institute Beijing China PKU-Nanjing Institute of Translational Medicine Nanjing China Genvivo Biotech Nanjing China Department of Biomedical Engineering College of Future Technology Peking University Beijing China ShanghaiTech University Shanghai China Chinese Institute for Brain Research (CIBR) Beijing China Beijing Advanced Innovation Center for Genomics (ICG) Peking University Beijing China University of Chinese Academy of Sciences Beijing China

Organic fluorophores are the keystone of advanced biological imaging. The vast chemical space of fluorophores has been extensively explored in search of molecules with ideal properties. However, within the current molecular constraints, there appears to be a trade-off between high brightness, robust photostability, and tunable biochemical properties. Herein we report a general strategy to systematically boost the performance of donor-acceptor-type fluorophores, such as rhodamines, by leveraging SO₂ and O-substituted azabicyclo[3.2.1] octane auxochromes. These bicyclic heterocycles give rise to a collection of ‘bridged’ dyes (BD) spanning the ultraviolet and visible range with top-notch quantum efficiencies, enhanced water solubility, and tunable cell-permeability. Notably, these azabicyclic fluorophores showed remarkable photostability compared to their tetramethyl or azetidine analogs while being completely resistant to oxidative photoblueing. Functionalized BD dyes are tailored for applications in single-molecule imaging, super-resolution imaging (STED and SIM) in fixed or live mammalian and plant cells, and live zebrafish imaging and chemogenetic voltage imaging. © The Author(s), under exclusive licence to Springer Nature America, Inc. 2025.

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Evaluation of emotion elicitation for patients with autistic spectrum disorder combined with cerebral palsy 1st

Evaluation of emotion elicitation for patients with autistic...

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1st International Conference on Advances in Electrical and Computer Technologies, ICAECT 2019

作者： Sindhu, N. Jerritta, S. Vels Institute of Science Technology and Advanced Studies Chennai India Department of ECE Government of Engineering College Thrissur Thrissur India Department of ECE Vels Institute of Science Technology and Advanced Studies Chennai India

ISBN: (纸本)9789811555572

The purpose of the work is to find out efficient stimuli to evoke emotions in children having autistic spectrum disorder combined with cerebral palsy. Experiment was conducted in the forenoon session to record the ECG signal of such children. The children were instructed to focus on the audio/video played as part of the process. The objective is to elicit different emotions in autistic spectrum disorder combined cerebral palsy patients. Children of age group 4–15 (13 children) were considered. A psychologist by clinical test can identify the elicited emotions. The emotions elicited in patients whose emotions are not explicitly conveyed can be included for analysis. Important features like heart rate RR interval, low- and high-frequency features obtained using discrete wavelet transform (DWT) were used for the analysis. The different stimuli based on audio clips and video clips were compared, and their performance was evaluated. Cerebral palsy children exposed to the above elicitation methods were observed to have less active autonomous nervous system compared to normal ones. Emotions in normal ones and autism spectrum disorder with cerebral palsy are being compared. A total of 23 normal persons of age ranging from 22 to 25 were considered for the experiment. The signals for everyone were recorded using Powerlab15T and db7 wavelet analysis done. SVM classifier classifies it as happy/sad. Audio is found to have better specificity for differentially abled children. © Springer Nature Singapore Pte Ltd 2020.

关键词： Discrete wavelet transforms

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Unveiling the Healing Mechanism of Nanopores in Ice Films

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Small 2025年

作者： Nan, Pengfei Wu, Kang Li, Qizhu Liu, Yangrui Wang, Hongzheng Lin, Yangjian Zhu, Jinlong Wu, Jing Lin, Fang Wang, Yumei Ge, Binghui Information Materials and Intelligent Sensing Laboratory of Anhui Province Leibniz International Joint Research Center of Materials Sciences of Anhui Province Institutes of Physical Science and Information Technology Anhui University Hefei230601 China Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing100190 China Songshan Lake Materials Laboratory Dongguan523808 China Instrumentation and Service Center for Physical Sciences Westlake University Zhejiang Hangzhou310024 China Shenzhen Key Laboratory of Natural Gas Hydrate Department of Physics & Academy for Advanced Interdisciplinary Studies Southern University of Science and Technology Shenzhen518055 China Cryo-EM Center Southern University of Science and Technology Shenzhen518055 China College of Electronic Engineering South China Agricultural University Guangdong Guangzhou510642 China

As a ubiquitous substance in nature, ice has attracted substantial research interest across a variety of fields, including physics, environmental science, biology, and cryopreservation. However, the intricate structural transformations within ice remain elusive owing to the stringent experimental constraints. Herein, the detailed evolution of ice nanopores, including expansion and healing, is investigated using advanced cryo-electron microscopy combined with low-dose techniques, and the underlying mechanisms are revealed through surface-free energy analysis. Three pivotal factors are identified as driving the evolution mechanism of ice nanopores: the nanopore geometry and dimensions and the thickness of the ice film. This research not only provides novel insights into the dynamic structural evolution of ice at the molecular scale but also paves the way for a deeper understanding of the fundamental properties and behaviors of ice. Moreover, the healing mechanism of the nanopores is anticipated to be utilized in ice manipulation and nanofabrication. © 2025 Wiley-VCH GmbH.

关键词： Nanopores

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Mild and ultrafast GLORI enables absolute quantification of m⁶A methylome from low-input samples

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Nature Methods 2025年 1-11页

作者： Sun, Hanxiao Lu, Bo Zhang, Zeyu Xiao, Ye Zhou, Zhe Xi, Lin Li, Zhichao Jiang, Zhe Zhang, Jiayi Wang, Meng Liu, Cong Ma, Yichen Peng, Jinying Wang, Xiu-Jie Yi, Chengqi State Key Laboratory of Protein and Plant Gene Research School of Life Sciences Peking University Beijing China Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing China Academy for Advanced Interdisciplinary Studies Peking University Beijing China Peking-Tsinghua Center for Life Sciences Peking University Beijing China School of Future Technology University of Chinese Academy of Sciences Beijing China Department of Chemical Biology and Synthetic and Functional Biomolecules Center College of Chemistry and Molecular Engineering Peking University Beijing China Beijing Advanced Center of RNA Biology (BEACON) Peking University Beijing China

Methods for absolute quantification of N6-methyladenosine (m6A) have emerged as powerful tools in epitranscriptomics. We previously reported GLORI, a chemical-assisted approach to achieve unbiased and precise m6A meas...

Methods for absolute quantification of N⁶-methyladenosine (m⁶A) have emerged as powerful tools in epitranscriptomics. We previously reported GLORI, a chemical-assisted approach to achieve unbiased and precise m⁶A measurement. However, its lengthy reaction time and severe RNA degradation have limited its applicability, particularly for low-input samples. Here, we present two updated GLORI approaches that are ultrafast, mild and enable absolute m⁶A quantification from one to two orders of magnitude less than the RNA starting material: GLORI 2.0 is compatible with RNA from ~10,000 cells and enhances sensitivity for both transcriptome-wide and locus-specific m⁶A detection;GLORI 3.0 further utilizes a reverse transcription-silent carrier RNA to achieve m⁶A quantification from as low as 500–1,000 cells. Using limited RNA from mouse dorsal hippocampus, we reveal a high modification level in synapse-related gene sets. We envision that the updated GLORI methods will greatly expand the applicability of absolute quantification of m⁶A in biology. © The Author(s), under exclusive licence to Springer Nature America, Inc. 2025.

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An investigation of the effects of hot rolling on the microstructure and mechanical behavior of nano-sized SiC particulates reinforced Al6063 alloy composites

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Materials Today: Proceedings 2022年 64卷 731-736页

作者： Sreeram, D. Pugazhenthi, R. Anbuchezhiyan, G. Saravanan, R. Veeranjaneyulu, K. Department of Mechanical Engineering Vels Institute of Science Technology & Advanced Studies Tamil Nadu Chennai 600117 India Department of Mechanical Engineering Saveetha School of Engineering Saveetha Institute of Medical and Technical Science Tamil Nadu Chennai 601205 India Department of Aeronautical Engineering MLR Institute of Technology Telangana Hyderabad 500043 India

This study investigated the properties of aluminum alloy composites reinforced with nano-SiC particles produced by stir casting and hot rolling at a temperature of 5500C. Microstructural analysis reveals that nano SiC particles are uniformly distributed with good bonding to the alloy Al6063. The nano SiC particles align in a rolling direction, and the volume phase was analysed as per ASTM standards. It was observed that due to grain refinement the porosity was reduced due to the inclusion of nano Sic. The tensile strength and hardness of synthesised hot rolled composites significantly increased owing to enhancement of grain refinement and reduction in porosity. © 2022

关键词： Aluminum alloys

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Behaviour of Lignosulphonate Amended Expansive Soil 1st

Behaviour of Lignosulphonate Amended Expansive Soil

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1st International Conference on Sustainable Practices and Innovations in Civil engineering, SPICE 2019

作者： Landlin, G. Soundarya, M.K. Bhuvaneshwari, S. Department of Civil Engineering SRM Institute of Science and Technology Chennai India Department of Civil Engineering Vels Institute of Science Technology and Advanced Studies Chennai India

ISBN: (纸本)9789811551000

Expansive soils are problematic soils which exhibit large volume change behaviour on exposure to moisture changes. These soils are often chemically treated to mitigate the volume change behaviour. The chemical treatment involves the addition of chemical additives and various other waste materials which can curtail the volume change behaviour. However, the usage of chemical additives leads to large environmental issues and affects the biodiversity of the surrounding environment. In an attempt to cater to these issues, a non-conventional additive, with a bio-polymer base namely Lignosulphonate is used for treating the expansive soil. The soil selected is of highly expansive in nature, and the additive is added in small percentages of 1, 1.5 and 3%, and its effects on various soil properties are evaluated. The bio-polymer based additive basically curtails swelling and has a good influence on strength and improvement of compaction characteristics. The microstructural aspects are also evaluated through XRD (X-Ray Diffraction) and SEM (Scanning Electron Microscope) techniques, in order to understand the changes at the microstructure level, particle orientation and probable formation of cementitious compounds, and the comprehensive behaviour of the additive amended expansive soil. The lignosulphonate-treated samples depicted a 5-fold increase in strength, due to the particle aggregation and floc formation. © 2021, Springer Nature Singapore Pte Ltd.

关键词： Microstructure

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Experimental analysis of nano additive blended in Mahua oil biodiesel on engine characteristics

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Materials Today: Proceedings 2022年 63卷 535-541页

作者： Ramasubramanian, S. Shai Sundram, V.S. Karikalan, L. Baskar, S. Kumar Sahu, Sandip Borkar, Dilip S. Kumar, Prashant Department of Automobile Engineering Vels Institute of Science Technology & Advanced Studies Tamil Nadu Chennai 600117 India Department of Mechanical Engineering Government Engineering College Bilaspur Chhattisgarh Bilaspur 495009 India Department of Mechanical Engineering Manoharbhai Patel Institute of Engineering and Technology Maharashtra Shahapur Bhandara 441906 India School of Mechanical Engineering Vellore Institute of Technology Tamil Nadu Vellore 632014 India

Fossil fuel depletion and environmental degradation are currently facing the planet. Increased automobile, power plants, and factories emit more carbon monoxide (CO), unburnt hydrocarbon (HC), and nitric oxide (NOx) emissions as a result of increased automobiles, power plants, and factories. As a result, the globe is looking for an alternative fuel that will not hurt the environment and will also be less expensive. It should also be renewable resources. It pushes the car into the next generation. Vegetables, which satisfy the need for physical and chemical qualities of mineral diesel in the current context. When vegetable oil is used in a diesel engine, it has a negative impact on performance and durability. As a result, the oil should be converted to biodiesel. Transesterification is a useful procedure for changing the properties of raw oil. One of the most essential solutions to the global energy dilemma is biodiesel. The performance and emission parameters of Mahua oil bio-diesel were investigated in this study (MOB). Additives are used to improve biodiesel's combustion properties. Tests were conducted across the whole spectrum of engine operation and under various load circumstances. Engine performance factors like as specific consumption, braking thermal efficiency, and exhaust gas emissions are reduced as biodiesel concentration is increased. MOB blends can be used to replace diesel in diesel engines used in transportation and agriculture. © 2022

关键词： Diesel engines

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