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Erratum to: Study of ϒ production in pPb collisions at = 8.16 TeV

Journal of High Energy Physics 2020年第2期2020卷 1-8页

作者： Aaij, R. Abellán Beteta, C. Adeva, B. Adinolfi, M. Aidala, C. A. Ajaltouni, Z. Akar, S. Albicocco, P. Albrecht, J. Alessio, F. Alexander, M. Alfonso Albero, A. Alkhazov, G. Alvarez Cartelle, P. Alves, A. A. Amato, S. Amerio, S. Amhis, Y. An, L. Anderlini, L. Andreassi, G. Andreotti, M. Andrews, J. E. Appleby, R. B. Archilli, F. d’Argent, P. Arnau Romeu, J. Artamonov, A. Artuso, M. Arzymatov, K. Aslanides, E. Atzeni, M. Audurier, B. Bachmann, S. Back, J. J. Baker, S. Balagura, V. Baldini, W. Baranov, A. Barlow, R. J. Barsuk, S. Barter, W. Bartolini, M. Baryshnikov, F. Batozskaya, V. Batsukh, B. Battig, A. Battista, V. Bay, A. Beddow, J. Bedeschi, F. Bediaga, I. Beiter, A. Bel, L. J. Belin, S. Beliy, N. Bellee, V. Belloli, N. Belous, K. Belyaev, I. Ben-Haim, E. Bencivenni, G. Benson, S. Beranek, S. Berezhnoy, A. Bernet, R. Berninghoff, D. Bertholet, E. Bertolin, A. Betancourt, C. Betti, F. Bettler, M. O. van Beuzekom, M. Bezshyiko, Ia. Bhasin, S. Bhom, J. Bifani, S. Billoir, P. Birnkraut, A. Bizzeti, A. Bjørn, M. Blago, M. P. Blake, T. Blanc, F. Blusk, S. Bobulska, D. Bocci, V. Boente Garcia, O. Boettcher, T. Bondar, A. Bondar, N. Borghi, S. Borisyak, M. Borsato, M. Bossu, F. Boubdir, M. Bowcock, T. J. V. Bozzi, C. Braun, S. Brodski, M. Brodzicka, J. Brossa Gonzalo, A. Brundu, D. Buchanan, E. Buonaura, A. Burr, C. Bursche, A. Buytaert, J. Byczynski, W. Cadeddu, S. Cai, H. Calabrese, R. Calladine, R. Calvi, M. Calvo Gomez, M. Camboni, A. Campana, P. Campora Perez, D. H. Capriotti, L. Carbone, A. Carboni, G. Cardinale, R. Cardini, A. Carniti, P. Carson, L. Carvalho Akiba, K. Casse, G. Cassina, L. Cattaneo, M. Cavallero, G. Cenci, R. Chamont, D. Chapman, M. G. Charles, M. Charpentier, Ph. Chatzikonstantinidis, G. Chefdeville, M. Chekalina, V. Chen, C. Chen, S. Chitic, S.-G. Chobanova, V. Chrzaszcz, M. Chubykin, A. Ciambrone, P. Cid Vidal, X. Ciezarek, G. Clarke, P. E. L. Clemencic, M. Cliff, H. V. Closier, J. Coco, V. Coelho, J. A. B. Cogan, J. Cogneras, E. Cojocariu, L. Collins, P. Colombo, T. Comerma-Montells, A. Co Nikhef National Institute for Subatomic Physics Amsterdam Netherlands Physik-Institut Universität Zürich Zürich Switzerland Instituto Galego de Física de Altas Enerxías (IGFAE) Universidade de Santiago de Compostela Santiago de Compostela Spain H.H. Wills Physics Laboratory University of Bristol Bristol United Kingdom University of Michigan Ann Arbor United States Clermont Université Université Blaise Pascal CNRS/IN2P3 LPC Clermont-Ferrand France University of Cincinnati Cincinnati United States INFN Laboratori Nazionali di Frascati Frascati Italy Fakultät Physik Technische Universität Dortmund Dortmund Germany European Organization for Nuclear Research (CERN) Geneva Switzerland School of Physics and Astronomy University of Glasgow Glasgow United Kingdom ICCUB Universitat de Barcelona Barcelona Spain Petersburg Nuclear Physics Institute (PNPI) Gatchina Russia Imperial College London London United Kingdom Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil INFN Sezione di Padova Padova Italy LAL Univ. Paris-Sud CNRS/IN2P3 Université Paris-Saclay Orsay France Center for High Energy Physics Tsinghua University Beijing China INFN Sezione di Firenze Firenze Italy Institute of Physics Ecole Polytechnique Fédérale de Lausanne (EPFL) Lausanne Switzerland INFN Sezione di Ferrara Ferrara Italy University of Maryland College Park United States School of Physics and Astronomy University of Manchester Manchester United Kingdom Physikalisches Institut Ruprecht-Karls-Universität Heidelberg Heidelberg Germany Aix Marseille Univ CNRS/IN2P3 CPPM Marseille France Institute for High Energy Physics (IHEP) Protvino Russia Syracuse University Syracuse United States Yandex School of Data Analysis Moscow Russia INFN Sezione di Cagliari Monserrato Italy Department of Physics University of Warwick Coventry United Kingdom Laboratoire Leprince-Ringuet Palaiseau France INFN Sezione di Genova Genova Italy National University of Science and Techno

In figure 11 of the original paper.

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Introducing evolutionary biologists to the analysis of big data: Guidelines to organize extended bioinformatics training courses

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Evolution: Education and Outreach 2018年第1期11卷 1-10页

作者： Faria, Rui Triant, Deborah Perdomo-Sabogal, Alvaro Overduin, Bert Bleidorn, Christoph Santana, Clara Isabel Bermudez Langenberger, David Indrischek, Henrike Aerts, Jan Engelhardt, Jan Engelken, Johannes Liebal, Katja Fasold, Mario Robb, Sofia Grath, Sonja Kolora, Sree Rohit Raj Carvalho, Tiago Salzburger, Walter Jovanovic, Vladimir Nowick, Katja CIBIO Centro de Investigação em Biodiversidade e Recursos Genéticos InBIO Laboratório Associado Universidade Do Porto Campus Agrário de Vairão Vairão 4485-661 Portugal IBE Institute of Evolutionary Biology (CSIC-UPF) Department of Experimental and Health Sciences Pompeu Fabra University Doctor Aiguader 88 Barcelona 08003 Spain Department of Animal and Plant Sciences University of Sheffield Sheffield United Kingdom Department of Biochemistry and Molecular Genetics University of Virginia Charlottesville 22908 VA United States TFome Research Group Bioinformatics Group Interdisciplinary Center of Bioinformatics Department of Computer Science University of Leipzig Härtelstrasse 16-18 Leipzig 04107 Germany Paul-Flechsig-Institute for Brain Research University of Leipzig Jahnallee 59 Leipzig 04109 Germany Faculty for Biology Chemistry and Pharmacy Freie Universität Berlin Königin-Luise-Straße 1-3 Berlin 14195 Germany Edinburgh Genomics University of Edinburgh Ashworth Laboratories King's Buildings Charlotte Auerbach Road Edinburgh EH9 3FL United Kingdom Museo Nacional de Ciencias Naturales Spanish Research Council (CSIC) José Gutiérrez Abascal 2 Madrid 28006 Spain German Centre for Integrative Biodiversity Research (IDiv) Halle-Jena-Leipzig Deutscher Platz 5e Leipzig 04103 Germany Grupo Rnomica Teórica y Computacional Departamento de Biologia Universidad Nacional de Colombia Bogota Colombia EcSeq Bioinformatics GmbH Sternwartenstraße 29 Leipzig 04103 Germany Computational Biology Department of Target Sciences GlaxoSmithKline Gunnels Wood Road Stevenage SG1 2NY United Kingdom Computational EvoDevo Group Department of Computer Science University of Leipzig Härtelstrasse 16-18 Leipzig 04107 Germany Bioinformatics Group Department of Computer Science University of Leipzig Härtelstrasse 16-18 Leipzig 04107 Germany Visual Data Analysis Lab ESAT/STADIUS KU Leuven Kasteelpark Arenberg 10 Leuven 3001 Belgium Imec KU Leuven Leuven Belgiu

Research in evolutionary biology has been progressively influenced by big data such as massive genome and transcriptome sequencing data, scalar measurements of several phenotypes on tens to thousands of individuals, as well as from collecting worldwide environmental data at an increasingly detailed scale. The handling and analysis of such data require computational skills that usually exceed the abilities of most traditionally trained evolutionary biologists. Here we discuss the advantages, challenges and considerations for organizing and running bioinformatics training courses of 2-3 weeks in length to introduce evolutionary biologists to the computational analysis of big data. Extended courses have the advantage of offering trainees the opportunity to learn a more comprehensive set of complementary topics and skills and allowing for more time to practice newly acquired competences. Many organizational aspects are common to any course, as the need to define precise learning objectives and the selection of appropriate and highly motivated instructors and trainees, among others. However, other features assume particular importance in extended bioinformatics training courses. To successfully implement a learning-by-doing philosophy, sufficient and enthusiastic teaching assistants (TAs) are necessary to offer prompt help to trainees. Further, a good balance between theoretical background and practice time needs to be provided and assured that the schedule includes enough flexibility for extra review sessions or further discussions if desired. A final project enables trainees to apply their newly learned skills to real data or case studies of their interest. To promote a friendly atmosphere throughout the course and to build a close-knit community after the course, allow time for some scientific discussions and social activities. In addition, to not exhaust trainees and TAs, some leisure time needs to be organized. Finally, all organization should be done while keeping

关键词： Active learning Bioinformatics Evolutionary biology Extended course Genomics High-throughput-sequencing Programming Sustainable course

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (vol 50, pg 1412, 2018)

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NATURE GENETICS 2018年第12期50卷 1755-1755页

作者： Evangelou, Evangelos Warren, Helen R. Mosen-Ansorena, David Mifsud, Borbala Pazoki, Raha Gao, He Ntritsos, Georgios Dimou, Niki Cabrera, Claudia P. Karaman, Ibrahim Fu Liang Ng Evangelou, Marina Witkowska, Katarzyna Tzanis, Evan Hellwege, Jacklyn N. Giri, Ayush Edwards, Digna R. Velez Sun, Yan V. Cho, Kelly Gaziano, J. Michael Wilson, Peter W. F. Tsao, Philip S. Kovesdy, Csaba P. Esko, Tonu Magi, Reedik Milani, Lili Almgren, Peter Boutin, Thibaud Debette, Stephanie Ding, Jun Giulianini, Franco Holliday, Elizabeth G. Jackson, Anne U. Li-Gao, Ruifang Lin, Wei-Yu Luan, Jian'an Mangino, Massimo Oldmeadow, Christopher Prins, Bram Peter Qian, Yong Sargurupremraj, Muralidharan Shah, Nabi Surendran, Praveen Theriault, Sebastien Verweij, Niek Willems, Sara M. Zhao, Jing-Hua Amouyel, Philippe Connell, John de Mutsert, Renee Doney, Alex S. F. Farrall, Martin Menni, Cristina Morris, Andrew D. Noordam, Raymond Pare, Guillaume Poulter, Neil R. Shields, Denis C. Stanton, Alice Thom, Simon Abecasis, Goncalo Amin, Najaf Arking, Dan E. Ayers, Kristin L. Barbieri, Caterina M. Batini, Chiara Bis, Joshua C. Blake, Tineka Bochud, Murielle Boehnke, Michael Boerwinkle, Eric Boomsma, Dorret I. Bottinger, Erwin P. Braund, Peter S. Brumat, Marco Campbell, Archie Campbell, Harry Chakravarti, Aravinda Chambers, John C. Chauhan, Ganesh Ciullo, Marina Cocca, Massimiliano Collins, Francis Cordell, Heather J. Davies, Gail de Borst, Martin H. de Geus, Eco J. Deary, Ian J. Deelen, Joris Del Greco, Fabiola M. Demirkale, Cumhur Yusuf Dorr, Marcus Ehret, Georg B. Elosua, Roberto Enroth, Stefan Erzurumluoglu, A. Mesut Ferreira, Teresa Franberg, Mattias Franco, Oscar H. Gandin, Ilaria Gasparini, Paolo Giedraitis, Vilmantas Gieger, Christian Girotto, Giorgia Goel, Anuj Gow, Alan J. Gudnason, Vilmundur Guo, Xiuqing Gyllensten, Ulf Hamsten, Anders Harris, Tamara B. Harris, Sarah E. Hartman, Catharina A. Havulinna, Aki S. Hicks, Andrew A. Hofer, Edith Hofman, Albert Hottenga, Jouke-Jan Huffman, Jennifer E. Hwang, Shih-Jen Ingelsson, Erik James, Alan Jansen Department of Epidemiology and Biostatistics Imperial College London London UK Department of Hygiene and Epidemiology University of Ioannina Medical School Ioannina Greece William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK National Institute for Health Research Barts Cardiovascular Biomedical Research Center Queen Mary University of London London UK MRC-PHE Centre for Environment and Health Imperial College London London UK Department of Mathematics Imperial College London London UK Division of Epidemiology Department of Medicine Institute for Medicine and Public Health Vanderbilt Genetics Institute Vanderbilt University Medical Center Tennessee Valley Healthcare System (626)/Vanderbilt University Nashville TN USA Vanderbilt Genetics Institute Vanderbilt Epidemiology Center Department of Obstetrics and Gynecology Vanderbilt University Medical Center Tennessee Valley Health Systems VA Nashville TN USA Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA Department of Biomedical Informatics Emory University School of Medicine Atlanta GA USA Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC) VA Boston Healthcare System Boston MA USA Division of Aging Department of Medicine Brigham and Women’s Hospital Department of Medicine Harvard Medical School Boston MA USA Atlanta VAMC and Emory Clinical Cardiovascular Research Institute Atlanta GA USA VA Palo Alto Health Care System Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA Nephrology Section Memphis VA Medical Center and University of Tennessee Health Science Center Memphis TN USA Estonian Genome Center University of Tartu Tartu Estonia Program in Medical and Population Genetics Broad Institute of Harvard and MIT Cambridge MA USA Department Clinical Sciences Malmö Lund University Malmö Sweden MRC Human Genetics Un

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.

关键词： Cardiovascular diseases Genome informatics Genome-wide association studies

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Updated measurement of decay-time-dependent CP asymmetries in D0→K+K− and D0→π+π− decays

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Physical Review D 2020年第1期101卷 012005-012005页

作者： R. Aaij C. Abellán Beteta T. Ackernley B. Adeva M. Adinolfi H. Afsharnia C. A. Aidala S. Aiola Z. Ajaltouni S. Akar P. Albicocco J. Albrecht F. Alessio M. Alexander A. Alfonso Albero G. Alkhazov P. Alvarez Cartelle A. A. Alves, Jr. S. Amato Y. Amhis L. An L. Anderlini G. Andreassi M. Andreotti F. Archilli P. d’Argent J. Arnau Romeu A. Artamonov M. Artuso K. Arzymatov E. Aslanides M. Atzeni B. Audurier S. Bachmann J. J. Back S. Baker V. Balagura W. Baldini A. Baranov R. J. Barlow S. Barsuk W. Barter M. Bartolini F. Baryshnikov G. Bassi V. Batozskaya B. Batsukh A. Battig V. Battista A. Bay M. Becker F. Bedeschi I. Bediaga A. Beiter L. J. Bel V. Belavin S. Belin N. Beliy V. Bellee K. Belous I. Belyaev E. Ben-Haim G. Bencivenni S. Benson S. Beranek A. Berezhnoy R. Bernet D. Berninghoff H. C. Bernstein E. Bertholet A. Bertolin C. Betancourt F. Betti M. O. Bettler M. van Beuzekom Ia. Bezshyiko S. Bhasin J. Bhom M. S. Bieker S. Bifani P. Billoir A. Bizzeti M. Bjørn M. P. Blago T. Blake F. Blanc S. Blusk D. Bobulska V. Bocci O. Boente Garcia T. Boettcher A. Boldyrev A. Bondar N. Bondar S. Borghi M. Borisyak M. Borsato J. T. Borsuk T. J. V. Bowcock C. Bozzi S. Braun A. Brea Rodriguez M. Brodski J. Brodzicka A. Brossa Gonzalo D. Brundu E. Buchanan A. Buonaura C. Burr A. Bursche J. S. Butter J. Buytaert W. Byczynski S. Cadeddu H. Cai R. Calabrese L. Calero Diaz S. Cali R. Calladine M. Calvi M. Calvo Gomez A. Camboni P. Campana D. H. Campora Perez L. Capriotti A. Carbone G. Carboni R. Cardinale A. Cardini P. Carniti K. Carvalho Akiba A. Casais Vidal G. Casse M. Cattaneo G. Cavallero R. Cenci J. Cerasoli M. G. Chapman M. Charles Ph. Charpentier G. Chatzikonstantinidis M. Chefdeville V. Chekalina C. Chen S. Chen A. Chernov S.-G. Chitic V. Chobanova M. Chrzaszcz A. Chubykin P. Ciambrone M. F. Cicala X. Cid Vidal G. Ciezarek F. Cindolo P. E. L. Clarke M. Clemencic H. V. Cliff J. Closier J. L. Cobbledick V. Coco J. A. B. Coelho J. Cogan E. Cogneras L. Cojocariu P. Collins T. Colombo A. Comerma-Montells A. Contu N. Cooke G. Coombs Nikhef National Institute for Subatomic Physics Amsterdam Netherlands Physik-Institut Universität Zürich Zürich Switzerland Oliver Lodge Laboratory University of Liverpool Liverpool United Kingdom Instituto Galego de Física de Altas Enerxías (IGFAE) Universidade de Santiago de Compostela Santiago de Compostela Spain H. H. Wills Physics Laboratory University of Bristol Bristol United Kingdom Université Clermont Auvergne CNRS/IN2P3 LPC Clermont-Ferrand France University of Michigan Ann Arbor Michigan USA (associated with Syracuse University Syracuse New York USA) INFN Sezione di Milano Milano Italy University of Cincinnati Cincinnati Ohio USA INFN Laboratori Nazionali di Frascati Frascati Italy Fakultät Physik Technische Universität Dortmund Dortmund Germany European Organization for Nuclear Research (CERN) Geneva Switzerland School of Physics and Astronomy University of Glasgow Glasgow United Kingdom ICCUB Universitat de Barcelona Barcelona Spain Petersburg Nuclear Physics Institute NRC Kurchatov Institute (PNPI NRC KI) Gatchina Russia Imperial College London London United Kingdom Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil LAL Université Paris-Sud CNRS/IN2P3 Université Paris-Saclay Orsay France INFN Sezione di Firenze Firenze Italy Institute of Physics Ecole Polytechnique Fédérale de Lausanne (EPFL) Lausanne Switzerland INFN Sezione di Ferrara Ferrara Italy Physikalisches Institut Ruprecht-Karls-Universität Heidelberg Heidelberg Germany Aix Marseille Université CNRS/IN2P3 CPPM Marseille France Institute for High Energy Physics NRC Kurchatov Institute (IHEP NRC KI) Protvino Russia Syracuse University Syracuse New York USA Yandex School of Data Analysis Moscow Russia INFN Sezione di Cagliari Monserrato Italy Department of Physics University of Warwick Coventry United Kingdom Department of Physics and Astronomy University of Manchester Manchester United Kingdom INFN Sezione di Genova Genova Italy INFN Sezione

A search for decay-time-dependent charge-parity (CP) asymmetry in D0→K+K− and D0→π+π− decays is performed at the LHCb experiment using proton-proton collision data recorded at a center-of-mass energy of 13 TeV, and corresponding to an integrated luminosity of 5.4 fb−1. The D0 mesons are required to originate from semileptonic decays of b hadrons, such that the charge of the muon identifies the flavor of the neutral D meson at production. The asymmetries in the effective decay widths of D0 and D¯0 mesons are determined to be AΓ(K+K−)=(−4.3±3.6±0.5)×10−4 and AΓ(π+π−)=(2.2±7.0±0.8)×10−4, where the uncertainties are statistical and systematic, respectively. The results are consistent with CP symmetry and, when combined with previous LHCb results, yield AΓ(K+K−)=(−4.4±2.3±0.6)×10−4 and AΓ(π+π−)=(2.5±4.3±0.7)×10−4.

关键词： Particle decays Particle interactions

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Preface

Communications in Computer and Information Science

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Communications in computer and Information science 2018年 934卷 V-VI页

作者： Kuznetsov, Sergei O. Osipov, Gennady S. Stefanuk, Vadim L. Department of Data Analysis and Artificial Intelligence National Research University Higher School of Economics Moscow Russia Federal Research Center Computer Science and Control Institute of Informatics Problems Moscow Russia Institute for Information Transmission Problems Russian Academy of Sciences Moscow Russia

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Prompt Λ _c ⁺ production in pPb collisions at √sNN=5.02 TeV

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Journal of High Energy Physics 2019年第2期2019卷 1-26页

作者： Aaij, R. Adeva, B. Adinolfi, M. Aidala, C.A. Ajaltouni, Z. Akar, S. Albicocco, P. Albrecht, J. Alessio, F. Alexander, M. Alfonso Albero, A. Ali, S. Alkhazov, G. Alvarez Cartelle, P. Alves, A.A. Amato, S. Amerio, S. Amhis, Y. An, L. Anderlini, L. Andreassi, G. Andreotti, M. Andrews, J.E. Appleby, R.B. Archilli, F. d’Argent, P. Arnau Romeu, J. Artamonov, A. Artuso, M. Arzymatov, K. Aslanides, E. Atzeni, M. Audurier, B. Bachmann, S. Back, J.J. Baker, S. Balagura, V. Baldini, W. Baranov, A. Barlow, R.J. Barsuk, S. Barter, W. Baryshnikov, F. Batozskaya, V. Batsukh, B. Battista, V. Bay, A. Beddow, J. Bedeschi, F. Bediaga, I. Beiter, A. Bel, L.J. Beliy, N. Bellee, V. Belloli, N. Belous, K. Belyaev, I. Ben-Haim, E. Bencivenni, G. Benson, S. Beranek, S. Berezhnoy, A. Bernet, R. Berninghoff, D. Bertholet, E. Bertolin, A. Betancourt, C. Betti, F. Bettler, M.O. van Beuzekom, M. Bezshyiko, Ia. Bhasin, S. Bhom, J. Bifani, S. Billoir, P. Birnkraut, A. Bizzeti, A. Bjørn, M. Blago, M.P. Blake, T. Blanc, F. Blusk, S. Bobulska, D. Bocci, V. Boente Garcia, O. Boettcher, T. Bondar, A. Bondar, N. Borghi, S. Borisyak, M. Borsato, M. Bossu, F. Boubdir, M. Bowcock, T.J.V. Bozzi, C. Braun, S. Brodski, M. Brodzicka, J. Brossa Gonzalo, A. Brundu, D. Buchanan, E. Buonaura, A. Burr, C. Bursche, A. Buytaert, J. Byczynski, W. Cadeddu, S. Cai, H. Calabrese, R. Calladine, R. Calvi, M. Calvo Gomez, M. Camboni, A. Campana, P. Campora Perez, D.H. Capriotti, L. Carbone, A. Carboni, G. Cardinale, R. Cardini, A. Carniti, P. Carson, L. Carvalho Akiba, K. Casse, G. Cassina, L. Cattaneo, M. Cavallero, G. Cenci, R. Chamont, D. Chapman, M.G. Charles, M. Charpentier, Ph. Chatzikonstantinidis, G. Chefdeville, M. Chekalina, V. Chen, C. Chen, S. Chitic, S.-G. Chobanova, V. Chrzaszcz, M. Chubykin, A. Ciambrone, P. Cid Vidal, X. Ciezarek, G. Clarke, P.E.L. Clemencic, M. Cliff, H.V. Closier, J. Coco, V. Coelho, J.A.B. Cogan, J. Cogneras, E. Cojocariu, L. Collins, P. Colombo, T. Comerma-Montells, A. Contu, A. Coombs, G. Coquereau, S. Corti, G. Corvo, M. Costa Sobra Centro Brasileiro de Pesquisas Físicas (CBPF) Rio de Janeiro Brazil Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil Center for High Energy Physics Tsinghua University Beijing China Univ. Grenoble Alpes Univ. Savoie Mont Blanc CNRS IN2P3-LAPP Annecy France Clermont Université Université Blaise Pascal CNRS/IN2P3 LPC Clermont-Ferrand France Aix Marseille Univ CNRS/IN2P3 CPPM Marseille France LAL Univ. Paris-Sud CNRS/IN2P3 Université Paris-Saclay Orsay France LPNHE Sorbonne Université Paris Diderot Sorbonne Paris Cité CNRS/IN2P3 Paris France I. Physikalisches Institut RWTH Aachen University Aachen Germany Fakultät Physik Technische Universität Dortmund Dortmund Germany Max-Planck-Institut für Kernphysik (MPIK) Heidelberg Germany Physikalisches Institut Ruprecht-Karls-Universität Heidelberg Heidelberg Germany School of Physics University College Dublin Dublin Ireland INFN Sezione di Bari Bari Italy INFN Sezione di Bologna Bologna Italy INFN Sezione di Ferrara Ferrara Italy INFN Sezione di Firenze Firenze Italy INFN Laboratori Nazionali di Frascati Frascati Italy INFN Sezione di Genova Genova Italy INFN Sezione di Milano-Bicocca Milano Italy INFN Sezione di Milano Milano Italy INFN Sezione di Cagliari Monserrato Italy INFN Sezione di Padova Padova Italy INFN Sezione di Pisa Pisa Italy INFN Sezione di Roma Tor Vergata Roma Italy INFN Sezione di Roma La Sapienza Roma Italy Nikhef National Institute for Subatomic Physics Amsterdam Netherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam Amsterdam Netherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences Kraków Poland AGH - University of Science and Technology Faculty of Physics and Applied Computer Science Kraków Poland National Center for Nuclear Research (NCBJ) Warsaw Poland Horia Hulubei National Institute of Physics and Nuclear Engineering Bucharest-Magurele Romania Petersburg Nuclear Physics Institute

The prompt production of Λ c + baryons is studied in proton-lead collisions collected with the LHCb detector at the LHC. The data sample corresponds to an integrated luminosity of 1.58 nb −1 recorded at a nucleon-nuc... 详细信息

The prompt production of Λ _c ⁺ baryons is studied in proton-lead collisions collected with the LHCb detector at the LHC. The data sample corresponds to an integrated luminosity of 1.58 nb ⁻¹ recorded at a nucleon-nucleon centre-of-mass energy of sNN=5.02 TeV. Measurements of the differential cross-section and the forwardbackward production ratio are reported for Λ _c ⁺ baryons with transverse momenta in the range 2 < p _T < 10 GeV/c and rapidities in the ranges 1.5 < y ^∗ < 4.0 and −4.5 < y ^∗ < −2.5 in the nucleon-nucleon centre-of-mass system. The ratio of cross-sections of Λ _c ⁺ baryons and D ⁰ mesons is also reported. The results are compared with next-to-leading order calculations that use nuclear parton distribution functions.[Figure not available: see fulltext.] © 2019, The Author(s).

关键词： Charm physics Forward physics Heavy Ion Experiments Heavy quark production

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Enabling QoE-aware Mobile Cloud Video Recording over Roadside Vehicular Networks

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China Communications 2016年第8期13卷 63-73页

作者： Tongtong Jiang Zhaobin Deng Weiwei Huang Guoqing Zhang Department of Computer Science Sun Yat-sen University Guangdong Province Key Laboratory of Big Data Analysis and Processing Sun Yat-sen University Collaborative Innovation Center of High Performance Computing National University of Defense Technology Institute of Computing Technology Chinese Academy of Sciences

Most of previous video recording devices in mobile vehicles commonly store captured video contents locally. With the rapid development of 4G/Wi Fi networks, there emerges a new trend to equip video recording devices with wireless interfaces to enable video uploading to the cloud for video playback in a later time point. In this paper, we propose a QoE-aware mobile cloud video recording scheme in the roadside vehicular networks, which can adaptively select the proper wireless interface and video bitrate for video uploading to the cloud. To maximize the total utility, we need to design a control strategy to carefully balance the transmission cost and the achieved QoE for users. To this purpose, we investigate the tradeoff between cost incurred by uploading through cellular networks and the achieved QoE of users. We apply the optimization framework to solve the formulated problem and design an online scheduling algorithm. We also conduct extensive trace-driven simulations and our results show that our algorithm achieves a good balance between the transmission cost and user QoE.

关键词： mobile cloud video vehicular networks quality-of-experience

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33 PAN-cancer whole genome sequencing reveals patterns of subclonal mutations, signature changes and selection

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ESMO Open 2018年 3卷 A15-A15页

作者： K. Haase S. Dentro I. Leshchiner J. Wintersinger A. Deshwar M. Tarabichi Q. Morris D. Wedge P. Van Loo The Francis Crick Institute Cancer Genomics Group London UK Broad Institute of MIT and Harvard Cancer Genome Analysis group Cambridge USA University of Toronto Department of Computer Science Toronto Canada University of Toronto Banting and Best Department of Medical Research Toronto Canada University of Oxford Big Data Institute Oxford UK

Introduction During their development, tumour cells accumulate somatic mutations, structural variants and copy number alterations (CNAs). Driver events facilitate clonal expansions and lead to intra-tumour heterogeneity (ITH). While ITH is an important therapeutic challenge, its degree among different cancer types is largely unknown. Material and methods The pan-cancer analysis of whole genomes (PCAWG) enabled us to characterise ITH in an unprecedented set of 2778 tumour samples representing 36 histologically distinct cancer types. We applied six CNA callers and eleven subclonal reconstruction algorithms to integrate their solutions into robust consensus copy number profiles and subclonal reconstructions. Results and discussions Our analysis revealed pervasive ITH in all examined cancer types. We found at least one subclone in 96.7% of the 1801 samples for which we had statistical power to detect subclones. In addition, we find that the average proportions of subclonal point mutations, indels, SVs and CNAs are highly variable across cancer types. These observations suggest distinct evolutionary narratives of each histological cancer type. analysis of dN/dS ratios shows clear signs of positive selection within both clonal and subclonal mutations. We also identified subclonal mutations in driver genes that are recurrently hit and we found a significant enrichment of subclonal mutations in genes responsible for chromatin regulation. More than 5% of tumours contain driver mutations in genes for which specific treatment is available only in subclones, indicating the importance of assessing the clonality of targeted mutations for clinical decisions. Mutational signatures in the analysed samples show changes in activity over the course of tumour development. Characteristic carcinogen signatures, e.g. UV light exposure in melanomas, make less contributions to subclonal than clonal mutations, while APOBEC-induced mutagenesis has increased activity during the subclonal phase.

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Angular analysis of the B+ → K∗+µ+µ− decay

arXiv

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arXiv 2020年

作者： Aaij, R. Beteta, C. Abellán Ackernley, T. Adeva, B. Adinolfi, M. Afsharnia, H. Aidala, C.A. Aiola, S. Ajaltouni, Z. Akar, S. Albrecht, J. Alessio, F. Alexander, M. Albero, A. Alfonso Aliouche, Z. Alkhazov, G. Cartelle, P. Alvarez Amato, S. Amhis, Y. An, L. Anderlini, L. Andreianov, A. Andreotti, M. Archilli, F. Artamonov, A. Artuso, M. Arzymatov, K. Aslanides, E. Atzeni, M. Audurier, B. Bachmann, S. Bachmayer, M. Back, J.J. Baker, S. Rodriguez, P. Baladron Balagura, V. Baldini, W. Leite, J. Baptista Barlow, R.J. Barsuk, S. Barter, W. Bartolini, M. Baryshnikov, F. Basels, J.M. Bassi, G. Batsukh, B. Battig, A. Bay, A. Becker, M. Bedeschi, F. Bediaga, I. Beiter, A. Belavin, V. Belin, S. Bellee, V. Belous, K. Belov, I. Belyaev, I. Bencivenni, G. Ben-Haim, E. Berezhnoy, A. Bernet, R. Berninghoff, D. Bernstein, H.C. Bertella, C. Bertolin, A. Betancourt, C. Betti, F. Bezshyiko, I. Bhasin, S. Bhom, J. Bian, L. Bieker, M.S. Bifani, S. Billoir, P. Birch, M. Bishop, F.C.R. Bizzeti, A. Bjørn, M. Blago, M.P. Blake, T. Blanc, F. Blusk, S. Bobulska, D. Boelhauve, J.A. Garcia, O. Boente Boettcher, T. Boldyrev, A. Bondar, A. Bondar, N. Borghi, S. Borisyak, M. Borsato, M. Borsuk, J.T. Bouchiba, S.A. Bowcock, T.J.V. Boyer, A. Bozzi, C. Bradley, M.J. Braun, S. Rodriguez, A. Brea Brodski, M. Brodzicka, J. Gonzalo, A. Brossa Brundu, D. Buonaura, A. Burr, C. Bursche, A. Butkevich, A. Butter, J.S. Buytaert, J. Byczynski, W. Cadeddu, S. Cai, H. Calabrese, R. Calefice, L. Diaz, L. Calero Cali, S. Calladine, R. Calvi, M. Gomez, M. Calvo Magalhaes, P. Camargo Camboni, A. Campana, P. Quezada, A.F. Campoverde Capelli, S. Capriotti, L. Carbone, A. Carboni, G. Cardinale, R. Cardini, A. Carli, I. Carniti, P. Akiba, K. Carvalho Vidal, A. Casais Casse, G. Cattaneo, M. Cavallero, G. Celani, S. Cerasoli, J. Chadwick, A.J. Chapman, M.G. Charles, M. Charpentier, P. Chatzikonstantinidis, G. Barajas, C.A. Chavez Chefdeville, M. Chen, C. Chen, S. Chernov, A. Chitic, S.-G. Chobanova, V. Cholak, S. Chrzaszcz, M. Rio de Janeiro Brazil Rio de Janeiro Brazil Center for High Energy Physics Tsinghua University Beijing China School of Physics State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China University of Chinese Academy of Sciences Beijing China Beijing China Institute of Particle Physics Central China Normal University Wuhan Hubei China Univ. Grenoble Alpes Univ. Savoie Mont Blanc CNRS IN2P3-LAPP Annecy France Université Clermont Auvergne CNRS IN2P3 LPC Clermont-Ferrand France Aix Marseille Univ CNRS IN2P3 CPPM Marseille France Université Paris-Saclay CNRS IN2P3 IJCLab Orsay France Palaiseau France LPNHE Sorbonne Université Paris Diderot Sorbonne Paris Cité CNRS IN2P3 Paris France I. Physikalisches Institut RWTH Aachen University Aachen Germany Fakultät Physik Technische Universität Dortmund Dortmund Germany Heidelberg Germany Physikalisches Institut Ruprecht-Karls-Universität Heidelberg Heidelberg Germany School of Physics University College Dublin Dublin Ireland INFN Sezione di Bari Bari Italy INFN Sezione di Bologna Bologna Italy INFN Sezione di Ferrara Ferrara Italy INFN Sezione di Firenze Firenze Italy INFN Laboratori Nazionali di Frascati Frascati Italy INFN Sezione di Genova Genova Italy INFN Sezione di Milano-Bicocca Milano Italy INFN Sezione di Milano Milano Italy INFN Sezione di Cagliari Monserrato Italy Universita degli Studi di Padova Universita e INFN Padova Italy INFN Sezione di Pisa Pisa Italy INFN Sezione di Roma Tor Vergata Roma Italy INFN Sezione di Roma La Sapienza Roma Italy Nikhef National Institute for Subatomic Physics Amsterdam Netherlands Nikhef National Institute for Subatomic Physics VU University Amsterdam Amsterdam Netherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences Kraków Poland AGH - University of Science and Technology Faculty of Physics and Applied Computer Science Kraków Poland Warsaw Poland Horia Hulubei Nation

We present an angular analysis of the B+ → K∗+(→ KS0π+)µ+µ− decay using 9 fb−1 of pp collision data collected with the LHCb experiment. For the first time, the full set of CP-averaged angular observables is measured in intervals of the dimuon invariant mass squared. Local deviations from Standard Model predictions are observed, similar to those in previous LHCb analyses of the isospin-partner B0 → K∗0µ+µ− decay. The global tension is dependent on which effective couplings are considered and on the choice of theory nuisance parameters. © 2020, CC BY.

关键词： Hadrons

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Hematologic and spirometric characteristics of Tajik and Kyrgyz highlanders in the Pamir Mountains

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American Journal of Human Biology 2020年第2期33卷

作者： Xierzhatijiang Sulaiman Wei-fang Xu Liu-Hong Cai Xiao-Yang Huang Lu-Feng Cheng Ya-Ping Zhang Department of Pharmacology School of Pharmacy Xinjiang Medical University Urumqi Xinjiang China Contribution: Data curation Formal analysis Investigation Visualization Writing - original draft Writing - review & editing Shenzhen Hospital of Guangzhou University of Chinese Medicine Shenzhen Guangdong China Contribution: Conceptualization Funding acquisition Investigation Chengdu Yumei Hospital Chengdu Sichuan China Contribution: Investigation The People's Hospital of Shawan County Shawan Xinjiang China Ya-Ping Zhang KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming Institute of Zoology Chinese Academy of Sciences 32 East Jiaochang Road Kunming Yunnan 650223 China. Contribution: Conceptualization Funding acquisition Methodology Supervision State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Kunming Yunnan China State Key Laboratory for Conservation and Utilization of Bio-Resources Yunnan University Kunming Yunnan China Kunming College of Life Science University of Chinese Academy of Sciences Kunming Yunnan China KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming Institute of Zoology Chinese Academy of Sciences Kunming Yunnan China Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Kunming Yunnan China Lu-Feng Cheng Department of Pharmacology School of Pharmacy Xinjiang Medical University 393 Xinyi Road Urumqi Xinjiang 830054 China.

Objectives In this study, we measured the hematologic and spirometric parameters of native Tajik and Kyrgyz highlanders in the Pamir Mountains to investigate adaptations to high altitude stressors. Methods Hematological parameters including arterial oxygen saturation (SaO 2 ), red blood cell (RBC) counts, and hemoglobin (Hb) concentration were measured on Sarikoli Tajik (n = 80; 3100 m), Wakhi Tajik (n = 48; 3500 m), and Kyrgyz (n = 64; 3250 m) in comparison to lowland Uyghurs (n = 50; 1300 m). Spirometric parameters including forced vital capacity (FVC), the first second of forced expiration (FEV1), and forced expiratory flow between 25% and 75% (FEF25-75) were measured. We also reported mountain sickness symptoms in these highlanders and conducted a multivariate regression analysis to analyze the association between these symptoms and the measured parameters. Results SaO 2 of Sarikoli Tajik, Wakhi Tajik, and Kyrgyz (91%-93.5%) are significantly lower than lowland Uyghurs, yet are comparable to other native highlanders at a similar altitude. RBC counts and Hb concentrations of all three highland populations are significantly increased compared to Uyghurs. FVC is lower in Sarikoli Tajik, Wakhi Tajik, and Kyrgyz (male: 3.48-3.86 L, female: 2.47-2.78 L) compared to Uyghurs. Combined with normal FEV1, elevated FEV1/FVC ratio, and FEF25-75, the spirometric patterns of these highlanders indicate restrictive lung disease. A high prevalence of mountain sickness symptoms such as headache and nausea was found in all three highland populations, and are attributed to low FVC and aging by regression analysis. Conclusion Tajik and Kyrgyz highlanders showed adaptation in SaO 2 , RBC, and Hb level, but poor performance in spirometry, which causes mountain sickness.

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