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Addendum to “Hum-PLoc: A novel ensemble classifier for predicting human protein subcellular localization” [Biochem. Biophys. Res. Commun. 347 (2006) 150–157]

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Biochemical and Biophysical Research Communications 2006年第4期348卷 1479-1479页

作者： Kuo-Chen Chou Hong-Bin Shen Gordon Life Science Institute 13784 Torrey Del Mar Drive San Diego CA 92130 USA Institute of Image Processing and Pattern Recognition Shanghai Jiaotong University 1954 Hua-Shan Road Shanghai 200030 China

EEG-Based Brain-Computer Interfaces Are Vulnerable to Backdoor Attacks

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arXiv 2020年

作者： Meng, Lubin Huang, Jian Zeng, Zhigang Jiang, Xue Yu, Shan Jung, Tzyy-Ping Lin, Chin-Teng Chavarriaga, Ricardo Wu, Dongrui Ministry of Education Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China Brainnetome Center National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing China La Jolla CA United States Center for Advanced Neurological Engineering Institute of Engineering in Medicine Ucsd La Jolla CA United States Centre of Artificial Intelligence Faculty of Engineering and Information Technology University of Technology Sydney Australia Zhaw DataLab Zürich University of Applied Sciences Winterthur8401 Switzerland

Research and development of electroencephalogram (EEG) based brain-computer interfaces (BCIs) have advanced rapidly, partly due to deeper understanding of the brain and wide adoption of sophisticated machine learning approaches for decoding the EEG signals. However, recent studies have shown that machine learning algorithms are vulnerable to adversarial attacks. This article proposes to use narrow period pulse for poisoning attack of EEG-based BCIs, which is implementable in practice and has never been considered before. One can create dangerous backdoors in the machine learning model by injecting poisoning samples into the training set. Test samples with the backdoor key will then be classified into the target class specified by the attacker. What most distinguishes our approach from previous ones is that the backdoor key does not need to be synchronized with the EEG trials, making it very easy to implement. The effectiveness and robustness of the backdoor attack approach is demonstrated, highlighting a critical security concern for EEG-based BCIs and calling for urgent attention to address it. Copyright © 2020, The Authors. All rights reserved.

关键词： Electroencephalography

EEG-Based Brain-Computer Interfaces Are Vulnerable to Backdoor Attacks

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Research Square

Research Square 2021年

作者： Meng, Lubin Huang, Jian Zeng, Zhigang Jiang, Xue Yu, Shan Jung, Tzyy-Ping Lin, Chin-Teng Chavarriaga, Ricardo Wu, Dongrui Ministry of Education Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan China Brainnetome Center and National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing China La Jolla CA United States Center for Advanced Neurological Engineering Institute of Engineering in Medicine UCSD La Jolla CA United States Centre of Artificial Intelligence Faculty of Engineering and Information Technology University of Technology Sydney Australia ZHAW DataLab Zürich University of Applied Sciences Winterthur8401 Switzerland

Research and development of electroencephalogram (EEG) based brain-computer interfaces (BCIs) have advanced rapidly, partly due to the wide adoption of sophisticated machine learning approaches for decoding the EEG signals. However, recent studies have shown that machine learning algorithms are vulnerable to adversarial attacks, e.g., the attacker can add tiny adversarial perturbations to a test sample to fool the model, or poison the training data to insert a secret backdoor. Previous research has shown that adversarial attacks are also possible for EEG-based BCIs. However, only adversarial perturbations have been considered, and the approaches are theoretically sound but very difficult to implement in practice. This article proposes to use narrow period pulse for poisoning attack of EEG-based BCIs, which is more feasible in practice and has never been considered before. One can create dangerous backdoors in the machine learning model by injecting poisoning samples into the training set. Test samples with the backdoor key will then be classified into the target class specified by the attacker. What most distinguishes our approach from previous ones is that the backdoor key does not need to be synchronized with the EEG trials, making it very easy to implement. The effectiveness and robustness of the backdoor attack approach is demonstrated, highlighting a critical security concern for EEG-based BCIs. © 2021, CC BY.

关键词： Electroencephalography

Video segmentation using multiple features based on EM algorithm

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Chinese Journal of Systems Engineering and Electronics 2004年第4期000卷

Object-based video segmentation is an important issue for many multimedia applications. A video segmentation method based on EM algorithm is proposed. We consider video segmentation as an unsupervised classification problem and apply EM algorithm to obtain the maximum-likelihood estimation of the Gaussian model parameters for model-based segmentation. We simultaneously combine multiple features (motion, color) within a maximum likelihood framework to obtain accurate segment results. We also use the temporal consistency among video frames to improve the speed of EM algorithm. Experimental results on typical MPEG-4 sequences and real scene sequences show that our method has an attractive accuracy and robustness.

关键词： video object segmentation maximum-likelihood estimation EM algorithm

Acceptance and generation of general wave by a natural observation filter

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ELECTRONICS AND COMMUNICATIONS IN JAPAN PART III-FUNDAMENTAL ELECTRONIC SCIENCE 1995年第11期78卷 1-8页

作者： Iijima, T Honorary Member Japan Advanced Institute of Science and Technology Ishikawa Japan 923-12 Taizo lijima:graduated with a B.E. degree from the Tokyo Institute of Technology in 1948 and received his Ph.D. degree later. He joined the Electro-Technical Laboratories in 1948and since then has been involved in research on electromagnetic theory pattern recognition theory image processing voice recognition and research and development of OCR etc. After serving as the head of Iijima Special Research Laboratories he became Professorat the Tokyo Institute of Technology in 1972. Later he became the Professor Emeritus of that Institute in 1986. He became a Professor at Tokyo Engineering University and Professor Emeritus of that University in 1991. In 1991 he became Professor at the Japan Advanced Institute of Science and Technology and was appointed Vice President of that Institute in 1992. He served successively as editor examiner secretary of general affairs inspector councilor committee-head of pattern recognition and specialized studies head of Tokyo chapter and vice president of this Institute. In 1991 he became the Honorary Member.He received the Paper Award from the Institute four times and the literary works Award once. He received the Achievement Award and the Distinguished Service Award in 1976 and 1989 respectively. He received the Purple Ribbon Medal from the Emperor in 1988.

During the past few years, there has been a series of papers published on the theory of the natural observation method. As one of the important applications of this theory, the problems of acceptance and generation of a general waveform are discussed here. The case of polynomial waveforms and its corresponding theory was published previously. A great extension of that theory which covers general waveforms is presented here and its full picture is clarified.

关键词： natural observation filter acceptance of a wave generation of a wave theory of natural observation of the normal type

Varifocal-Net: A Chromosome Classification Approach Using Deep Convolutional Networks

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arXiv 2018年

作者： Qin, Yulei Wen, Juan Zheng, Hao Huang, Xiaolin Yang, Jie Song, Ning Zhu, Yue-Min Wu, Lingqian Yang, Guang-Zhong Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Shanghai200240 China Center for Medical Genetics School of Life Sciences Central South University Changsha410078 China Shanghai Key Laboratory of Reproductive Medicine School of Medicine Shanghai Jiao Tong University Shanghai200025 China Diagens-Hangzhou Hangzhou311121 China University Lyon INSA Lyon CNRS INSERM CREATIS UMR 5220 U1206F-69621 France Hamlyn Centre for Robotic Surgery Imperial College London SW72AZ United Kingdom

Chromosome classification is critical for karyotyping in abnormality diagnosis. To expedite the diagnosis, we present a novel method named Varifocal-Net for simultaneous classification of chromosomes type and polarity using deep convolutional networks. The approach consists of one global-scale network (G-Net) and one local-scale network (L-Net). It follows three stages. The first stage is to learn both global and local features. We extract global features and detect finer local regions via the G-Net. By proposing a varifocal mechanism, we zoom into local parts and extract local features via the L-Net. Residual learning and multi-task learning strategies are utilized to promote high-level feature extraction. The detection of discriminative local parts is fulfilled by a localization subnet of the G-Net, whose training process involves both supervised and weakly-supervised learning. The second stage is to build two multi-layer perceptron classifiers that exploit features of both two scales to boost classification performance. The third stage is to introduce a dispatch strategy of assigning each chromosome to a type within each patient case, by utilizing the domain knowledge of karyotyping. Evaluation results from 1909 karyotyping cases showed that the proposed Varifocal-Net achieved the highest accuracy per patient case (%) of 99.2 for both type and polarity tasks. It outperformed state-of-the-art methods, demonstrating the effectiveness of our varifocal mechanism, multi-scale feature ensemble, and dispatch strategy. The proposed method has been applied to assist practical karyotype diagnosis. Copyright © 2018, The Authors. All rights reserved.

关键词： Computer aided diagnosis

Unsupervised Local Discrimination for Medical images

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arXiv 2021年

作者： Chen, Huai Wang, Renzhen Wang, Xiuying Li, Jieyu Fang, Qu Li, Hui Bai, Jianhao Peng, Qing Meng, Deyu Wang, Lisheng Institute of Image Processing and Pattern Recognition Department of Automation Shanghai Jiao Tong University Shanghai200240 China School of Mathematics and Statistics Ministry of Education Key Lab of Intelligent Networks and Network Security Xi’an Jiaotong University Xi’an710049 China The School of Computer Science The University of Sydney SydneyNSW2006 Australia Department of Ophthalmology Shanghai Tenth People’s Hospital Tongji University Shanghai200240 China The Cooperative Medianet Innovation Center Shanghai Jiao Tong University Shanghai200240 China The Changchun GeneScience Pharmaceutical Co. LTD China

Contrastive learning, which aims to capture general representation from unlabeled images to initialize the medical analysis models, has been proven effective in alleviating the high demand for expensive annotations. Current methods mainly focus on instance-wise comparisons to learn the global discriminative features, however, pretermitting the local details to distinguish tiny anatomical structures, lesions, and tissues. To address this challenge, in this paper, we propose a general unsupervised representation learning framework, named local discrimination (LD), to learn local discriminative features for medical images by closely embedding semantically similar pixels and identifying regions of similar structures across different images. Specifically, this model is equipped with an embedding module for pixel-wise embedding and a clustering module for generating segmentation. And these two modules are unified through optimizing our novel region discrimination loss function in a mutually beneficial mechanism, which enables our model to reflect structure information as well as measure pixel-wise and region-wise similarity. Furthermore, based on LD, we propose a center-sensitive one-shot landmark localization algorithm and a shape-guided cross-modality segmentation model to foster the generalizability of our model. When transferred to downstream tasks, the learned representation by our method shows a better generalization, outperforming representation from 18 state-of-the-art (SOTA) methods and winning 9 out of all 12 downstream tasks. Especially for the challenging lesion segmentation tasks, the proposed method achieves significantly better performances. The source codes are publicly available at https://***/HuaiChen-1994/LDLearning. Copyright © 2021, The Authors. All rights reserved.

关键词： Embeddings

A Region-Based Representation of images in MARS

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Journal of VLSI Signal processing Systems for Signal, image, and Video Technology 1998年第1-2期20卷 137-150页

作者： Servetto, Sergio D. Rui, Yong Ramchandran, Kannan Huang, Thomas S. Beckman Inst. Adv. Sci. and Technol. Univ. Illinois at Urbana-Champaign Urbana IL 61801 United States Universidad Nacional de La Plata Argentina Univ. Illinois at Urbana-Champaign United States Comp. Res. Adv. Applications Group IBM Argentina Argentina Image Formation and Processing Group Beckman Institute UIUC United States Department of Computer Science UNLP Argentina Dept. of Elec. and Comp. Engineering UIUC United States Multimedia Commun. Res. Department Bell Laboratories Murray Hill NJ United States Info. Sciences Research Department AT and T Labs. Florham Park NJ United States Department of Computer Science UIUC United States Southeast University China Tsinghua University China University of Illinois Urbana-Champaign IL United States Image Formation and Processing Group Beckman Inst. Advance Sci. Technol. UIUC United States Vis. Technol. Grp. of Microsoft Res. Redmond WA United States City College of New York United States Columbia University United States AT and T Bell Labs. United States Ctr. for Telecommunications Research Columbia University United States Elec. and Comp. Eng. Department United States Beckman Institute Coordinated Science Laboratory IL United States IEEE Signal Processing Society United States IEEE IMDSP Technical Committee United States IEEE Transactions on Image Proc. United States National Taiwan University Taipei Taiwan Massachusetts Inst. of Technology Cambridge MA United States Department of Electrical Engineering MIT United States School of Electrical Engineering United States Lab. for Info. and Signal Processing Purdue University United States Dept. of Elec. and Comp. Engineering United States Coordinated Science Laboratory United States Image Formation and Processing Group Beckman Inst. Adv. Sci. and Technol. United States MIT Lincoln Laboratory IBM Thomas J. Watson Research Center Rheinishes Landes Museum Bonn Germany Swiss Institutes of Technology Zurich Switzerland Swiss Institutes of Technology Lausanne S

We study the problem of representing images within a multimedia Database Management System (DBMS), in order to support fast retrieval operations without compromising storage efficiency. To achieve this goal, we propose new image coding techniques which combine a wavelet representation, embedded coding of the wavelet coefficients, and segmentation of image-domain regions in the wavelet domain. A bitstream is generated in which each image region is encoded independently of other regions, without having to explicitly store information describing the regions. Simulation results show that our proposed algorithms achieve coding performance which compares favorably, both perceptually and objectively, to that achieved using state-of-the-art image/video coding techniques while additionally providing region-based support.

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A Recent Survey of Vision Transformers for Medical image Segmentation

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arXiv 2023年

作者： Khan, Asifullah Rauf, Zunaira Khan, Abdul Rehman Rathore, Saima Khan, Saddam Hussain Shah, Sahar Farooq, Umair Asif, Hifsa Asif, Aqsa Zahoora, Umme Khalil, Rafi Ullah Qamar, Suleman Asif, Umme Hani Khan, Faiza Babar Majid, Abdul Gwak, Jeonghwan Pattern Recognition Lab Department of Computer & Information Sciences Pakistan Institute of Engineering & Applied Sciences Nilore Islamabad45650 Pakistan Pakistan Institute of Engineering & Applied Sciences Nilore Islamabad45650 Pakistan Center for Mathematical Sciences Pakistan Institute of Engineering & Applied Sciences Nilore Islamabad45650 Pakistan Avid Radio pharmaceuticals PhiladelphiaPA United States Eli Lilly and Company IndianapolisIN United States Swat Pakistan Air University E-9 Islamabad44230 Pakistan Digital Image Processing Lab Department of Computer Science Islamia College Peshawar Pakistan Pakistan Institute of Engineering & Applied Sciences Nilore Islamabad45650 Pakistan Department of Software Korea National University of Transportation Chungju27469 Korea Republic of

Medical image segmentation plays a crucial role in various healthcare applications, enabling accurate diagnosis, treatment planning, and disease monitoring. In recent years, Vision Transformers (ViTs) have emerged as a promising technique for addressing the challenges in medical image segmentation. In medical images, structures are usually highly interconnected and globally distributed. ViTs utilize their multi-scale attention mechanism to model the long-range relationships in the images. However, they do lack image-related inductive bias and translational invariance, potentially impacting their performance. Recently, researchers have come up with various ViT-based approaches that incorporate CNNs in their architectures, known as Hybrid Vision Transformers (HVTs) to capture local correlation in addition to the globa l information in the images. This survey paper provides a detailed review of the recent advancements in ViTs and HVTs for medical image segmentation. Along with the categorization of ViT and HVT-based medical image segmentation approaches we also present a detailed overview of their real-time applications in several medical image modalities. This survey may serve as a valuable resource for researchers, healthcare practitioners, and students in understanding the state-of-the-art approaches for ViT-based medical image segmentation. Copyright © 2023, The Authors. All rights reserved.

关键词： Diagnosis