Current wireless network simulators provide very detailed and deterministic models of the network protocol layers, whereas rather simple and stochastic models, based on the signal-to-noise ratio, are used for the simu...
详细信息
Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in ...
详细信息
Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex genome-wide association study (GWAS) loci and may disentangle the role of different tissues in disease development. We used the largest eQTL reference panel for the dorso-lateral prefrontal cortex (DLPFC) to create a set of gene expression predictors and demonstrate their utility. We applied DLPFC and 12 GTEx-brain predictors to 40,299 schizophrenia cases and 65,264 matched controls for a large transcriptomic imputation study of schizophrenia. We identified 413 genic associations across 13 brain regions. Stepwise conditioning identified 67 non-MHC genes, of which 14 did not fall within previous GWAS loci. We identified 36 significantly enriched pathways, including hexosaminidase-A deficiency, and multiple porphyric disorder pathways. We investigated developmental expression patterns among the 67 non-MHC genes and identified specific groups of pre- and postnatal expression.
Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrot...
详细信息
This paper introduces a cognitive architecture for a humanoid robot to engage in a proactive, mixed-initiative exploration and manipulation of its environment, where the initiative can originate from both the human an...
详细信息
Depending on traffic density and environmental influences, the radio channel in Vehicular Ad-Hoc Networks (VANETs) can be a limited resource. The Shannon-Hartley theorem gives a theoretical maximum amount of data whic...
详细信息
Depending on traffic density and environmental influences, the radio channel in Vehicular Ad-Hoc Networks (VANETs) can be a limited resource. The Shannon-Hartley theorem gives a theoretical maximum amount of data which can be transmitted per time unit under given channel conditions. This limitation can be exceeded by using multi-antenna approaches commonly known as multiple-input, multiple-output (MIMO) communication systems. While these systems are already common in both infrastructural Wireless LAN (i.e. IEEE 802.11n or IEEE 802.11ac) and in modern cellular mobile networks (i.e. Long Term Evolution), the IEEE 802.11p standard for vehicleto- vehicle communication still comes without any multi-antenna approaches. In this paper we show in a simulation study that compared to plain IEEE 802.11p a MIMO-extended PHY layer based on IEEE 802.11p offers a considerably higher robustness against short-term fading caused by the vehicles' mobility and other channel-caused adverseness. Therefore we implemented a MIMO-extended PHY model using Orthogonal Space-time Block Codes (OSTBC) and linked the PHY model to a realistic MIMO radio channel model that is based on a large measurement campaign.
This paper addresses the problem of distributed state estimation in formations of vehicles with time-varying measurement topology. One or more vehicles have access to measurements of their own state, while the rest mu...
详细信息
Neurofeedback(NF)training is an operant conditioning procedure which regulates brain activity for human cognition,peak performance and health *** paper briefly introduces the new progress in neurofeedback research in ...
详细信息
Neurofeedback(NF)training is an operant conditioning procedure which regulates brain activity for human cognition,peak performance and health *** paper briefly introduces the new progress in neurofeedback research in optimizing cognition and behavior performance including memory,peripheral vision,physical balance and brain computer interface(BCI)in our research group.
Research objective: Regulation of brain activity by neurofeedback(NF)training has been widely applied in treatment of human psychological disorders,improvement of human cognitive performance and recently enhancement o...
详细信息
Research objective: Regulation of brain activity by neurofeedback(NF)training has been widely applied in treatment of human psychological disorders,improvement of human cognitive performance and recently enhancement of brain-computer interfaces(BCIs)***,no study has investigated whether training the same EEG feature but with different training direction has the reverse effects on some *** alpha neurofeedback,it has been demonstrated that alpha up-regulation NF has positive effects on short term memory enhancement while alpha down-regulation NF could improve steady state visual evoked potential BCI ***,it is unknown whether alpha down-regulation NF has side effects on short term ***,this study aimed to investigate: 1)whether multi-session NF training can decrease alpha activity and 2)whether this NF training has side effects in cognitive test of short term ***: A total of 19 participants performed 10 sessions of individualized alpha down-regulation neurofeedback training with 5 sessions per *** session had three 1-min trials with an interval of 5 s between two consecutive *** and after the 5 sessions of NF training in each day,three 30-s eyes open and three 30-s eyes closed resting baselines were recorded.9 in 19 participants performed forward and backward digit span as short term memory assessment before and after all training *** were trained to decrease their amplitude in individual alpha band(IAB)which is defined as band ranges from peak alpha frequency(PAF)-4 Hz to PAF+2 ***: 14 out of total 19 subjects could decrease the training parameter,their IAB amplitude,over training *** terms of the cognitive performance,neither forward nor backward digit span performance had significant change between before and after the alpha down-regulation neurofeedback training,indicating that this type of training has no side effects in short term ***
暂无评论