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The effect of wearable technology on badminton learning performance: a multiple feedback WISER model in physical education

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Smart learning Environments 2023年第1期10卷 1-21页

作者： Lin, Kuo-Chin Hung, Hui-Chun Chen, Nian-Shing Center for Physical and Health Education National Sun Yat-sen University Kaohsiung City Taiwan Graduate Institute of Network Learning Technology National Central University Taoyuan City Taiwan Institute for Research Excellence in Learning Sciences Program of Learning Sciences National Taiwan Normal University Taipei City Taiwan

Traditional physical education mainly relies on the instructor’s verbal explanations and physical demonstrations. However, learners might be confused about whether their movements and positions are correct. Moreover, a typical badminton class has approximately 50 students, creating a huge teaching load for an instructor. To reduce the instructor’s workload and improve learners’ badminton performance, a multiple feedback WISER model was designed for badminton classes. The model provides visual feedback, information feedback, and verbal guidance to learners. In this study, a quasi-experiment was designed and participants were divided into experimental and control groups. The experimental group adopted the multiple feedback WISER model while the control group applied the conventional method. The teaching experiment lasted for 8 weeks with 46 participants in the experimental group and 50 participants in the control group, respectively. To measure the learning performance, a movement detection system using wearable technology was utilized. The results indicate that the experimental group, which used the multiple feedback WISER model, outperformed the control group, which used traditional teaching methods, on badminton clear and smash skill learning (Clear: p < .001, EG = 71.03, CG = 54.76; Smash: p < .01, EG = 82.79, CG = 72.22). Further analysis reveals that the multiple feedback is more beneficial for learners with lower initial skill levels (Clear: p < .05, Lower = 63.21, Higher = 46.99; Smash: p < .001, Lower = 77.67, Higher = 39.39)

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An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration

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Nature Communications 2025年第1期16卷 1-21页

作者： Leventhal, Matthew J. Zanella, Camila A. Kang, Byunguk Peng, Jiajie Gritsch, David Liao, Zhixiang Bukhari, Hassan Wang, Tao Pao, Ping-Chieh Danquah, Serwah Benetatos, Joseph Nehme, Ralda Farhi, Samouil Tsai, Li-Huei Dong, Xianjun Scherzer, Clemens R. Feany, Mel B. Fraenkel, Ernest MIT Ph.D. Program in Computational and Systems Biology Cambridge MA United States Department of Biological Engineering Massachusetts Institute of Technology Cambridge MA United States Broad Institute of Harvard and MIT Cambridge MA United States Department of Pathology Brigham and Women’s Hospital and Harvard Medical School Boston MA United States Spatial Technology Platform Broad Institute of Harvard and MIT Cambridge MA United States Precision Neurology Program Brigham and Women’s Hospital and Harvard Medical school Boston MA United States APDA Center for Advanced Parkinson’s Disease Research Brigham and Women’s Hospital and Harvard Medical School Boston MA United States Picower Institute for Learning and Memory Massachusetts Institute of Technology Cambridge MA United States Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Cambridge MA United States Stanley Center for Psychiatric Research Broad Institute of Harvard and MIT Cambridge MA United States School of Computer Science Northwestern Polytechnical University Xi’an China Stephen and Denise Adams Center of Yale School of Medicine New Haven CT United States

Despite years of intense investigation, the mechanisms underlying neuronal death in Alzheimer’s disease, remain incompletely understood. To define relevant pathways, we conducted an unbiased, genome-scale forward genetic screen for age-associated neurodegeneration in Drosophila. We also measured proteomics, phosphoproteomics, and metabolomics in Drosophila models of Alzheimer’s disease and identified Alzheimer’s genetic variants that modify gene expression in disease-vulnerable neurons in humans. We then used a network model to integrate these data with previously published Alzheimer’s disease proteomics, lipidomics and genomics. Here, we computationally predict and experimentally confirm how HNRNPA2B1 and MEPCE enhance toxicity of the tau protein, a pathological feature of Alzheimer’s disease. Furthermore, we demonstrated that the screen hits CSNK2A1 and NOTCH1 regulate DNA damage in Drosophila and human stem cell-derived neural progenitor cells. Our study identifies candidate pathways that could be targeted to ameliorate neurodegeneration in Alzheimer’s disease. © The Author(s) 2025.

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Anterograde Trans-Synaptic Tagging Mediated by Adeno-Associated Virus

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Neuroscience Bulletin 2017年第3期33卷 348-350页

作者： Fei Zhao Hai-Fei Jiang Wen-Bo Zeng Yousheng Shu Min-Hua Luo Shumin Duan State Key Laboratory of Virology Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences Wuhan Institute of Virology Chinese Academy of Sciences State Key Laboratory of Cognitive Neuroscience and Learning IDG/Mc Govern Institute for Brain ResearchSchool of Brain and Cognitive Sciences the Collaborative Innovation Center for Brain Science Beijing Normal University Department of Neurobiology Key Laboratory of Medical Neurobiology of the Ministry of Health of China Key Laboratory of Neurobiology Zhejiang University School of Medicine

Trans-neuronal viral tracing is becoming one of the most important methods for mapping neuronal circuit connections,but an anterograde trans-synaptic tracer compatible with functional assays is still ***-associated virus（AAV）is replication-defective,and its production of offspring needs the help of adenovirus（AV）[1]or herpesvirus co-infection[2].The replication deficiency,non-pathogenicity,easy manipulability,

关键词： neuronal herpesvirus offspring replication pathogenicity synaptic tracing Associated adenovirus titer

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Application of Metacognitive Planning Scaffolding for the Cultivation of Computational Thinking

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Journal of Educational Computing research 2023年第6期61卷 1123 - 1142页

作者： Ying Zhou Ching Sing Chai Xiuting Li Chao Ma Baoping Li Ding Yu Jyh-Chong Liang Faculty of Education Beijing Normal University Beijing China Department of Curriculum and Instruction The Chinese University of Hong Kong Hong Kong China Program of Learning Sciences and Institute for Research Excellence in Learning Sciences National Taiwan Normal University Taipei Taiwan

Computational thinking is a way of thinking that helps people “think like a computer scientist” to solve practical problems. However, practicing computational thinking through programming is dependent on the problem solvers’ metacognition. This study investigated students’ metacognitive planning and problem-solving performance in programming through two quantitative studies. First, we analyzed the performance of metacognitive planning and of problem solving through the programming of 21 freshmen, and found that the metacognitive planning performance related to “problem description” and “program comprehension” was significantly correlated with problem-solving performance. Second, semi-scaffolding and full-scaffolding were designed based on the first study. Another 89 freshmen were randomly divided into three groups and were asked to write their programming plan with no-scaffolding, semi-scaffolding, or with full-scaffolding. ANCOVA revealed that the problem-solving performance of the no-scaffolding group was significantly weaker than that of the other two groups, but there was no significant difference between the semi-scaffolding and the full-scaffolding groups. The study indicated that semi-scaffolding had a similar effect to full-scaffolding on problem-solving performance. The study suggests that teachers should emphasize supporting students’ “problem description” and “program comprehension” using semi-scaffolding. This scaffolding technique is sufficient and efficient for training students’ computational thinking through problem solving in programming.

关键词： computational thinking problem solving through programming metacognitive planning scaffolding experimental study

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The Rationale for Student Online Exhibitions: A Bibliometrics Analysis

The Rationale for Student Online Exhibitions: A Bibliometric...

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11th International Conference on Information and Education Technology, ICIET 2023

作者： Prabowo, Thoriq Tri Sitthiworachart, Jirarat Hong, Jon Chao King Mongkut's Institute of Technology Ladkrabang School of Industrial Education and Technology Bangkok Thailand National Taiwan Normal University Institute for Research Excellence in Learning Sciences Taipei Taiwan

ISBN: (纸本)9781665465489

research on increasing student interest and learning attitudes continues to grow. Several people have studied online exhibitions, which are considered capable of increasing student learning participation. Assessing the status and trend of careful research will give a broader perspective and reference for upcoming research. However, in the Scopus database, only 116 documents related to student online exhibitions exist. Therefore, we aim to explore bibliographic aspects of publications about student online exhibitions using bibliometrics analysis. Technologies and its advantages are the dominant discussions. Most of the documents were from the highest citations were journals with a Q1 ranking of quartiles. This topic has been studied since 1995, with 2021 being the peak. English is the majority language used from retrieved documents originating from these 47 countries. However, results of this study indicated that rarely studies have made such a deep understanding on how technology impact online exhibition. © 2023 IEEE.

关键词： Students

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Effect of embedding a cognitive diagnosis into the adaptive dynamic assessment of spatial geometry learning

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Interactive learning Environments 2023年第2期31卷 890-907页

作者： Lin-Jung Wu Kuo-En Chang Graduate Institute of Information and Computer Education Institute for Research Excellence in Learning Sciences National Taiwan Normal University Taipei Taiwan

ABSTRACTABSTRACTTo achieve adaptive learning, a dynamic assessment system equipped with a cognitive diagnosis was developed for this study, which adopts a three-stage model of diagnosis-intervention-assessment. To examine how this system influenced spatial geometry learning, the study used a quasi-experimental method to investigate student learning outcomes between different groups. One hundred sixteen junior high school students participating in the experiment were divided into experimental and control groups. Experimental group engaged in adaptive learning as they corrected their misconceptions in the learning intervention stage by using learning content provided according to their cognitive diagnosis results. Control group engaged in nonadaptive learning; they corrected misconceptions using self-selected learning content and thus engaged in learning activities that were not focused on their misconceptions. The results revealed that the adaptive learning students exhibited learning performance and misconception correction ratios superior to those in the control group. Through analysis, we discovered that nearly half of the nonadaptive learning students failed to select appropriate learning content for correcting their misconceptions. In addition, the time spent on learning by the students in the two groups was significantly different; the adaptive learning students spent significantly less time on learning than the nonadaptive students, thus exhibiting higher learning efficiency.

关键词： Cognitive diagnosis adaptive learning dynamic assessment spatial geometry learning Bayesian network

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Transcriptome dynamics of hippocampal neurogenesis in macaques across the lifespan and aged humans

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细胞研究（英文版） 2022年第8期32卷 729-743页

作者： Wei Wang Mengdi Wang Meng Yang Bo Zeng Wenying Qiu Qiang Ma Xiaoxi Jing Qianqian Zhang Bosong Wang Chonghai Yin Jiyao Zhang Yuxin Ge Yufeng Lu Weizhi Ji Qian Wu Chao Ma Xiaoqun Wang State Key Laboratory of Cognitive Neuroscience and Learning IDG/McGovern Institute for Brain ResearchBeijing Normal UniversityBeijingChina State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence Technology(Shanghai)Institute of BiophysicsChinese Academy of SciencesBeijingChina State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence Technology(Shanghai)Institute of BiophysicsChinese Academy of SciencesBeijingChina Changping Laboratory BeijingChina University of Chinese Academy of Sciences BeijingChina State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence Technology(Shanghai)Institute of BiophysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina Changping Laboratory BeijingChina Institute of Basic Medical Sciences Neuroscience CenterNational Human Brain Bank for Development and FunctionChinese Academy of Medical Sciences Department of Human Anatomy Histology and EmbryologySchool of Basic MedicinePeking Union Medical CollegeBeijingChina State Key Laboratory of Cognitive Neuroscience and Learning IDG/McGovern Institute for Brain ResearchBeijing Normal UniversityBeijingChina State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence Technology(Shanghai)Institute of BiophysicsChinese Academy of SciencesBeijingChina Yunnan Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunmingYunanChina State Key Laboratory of Cognitive Neuroscience and Learning IDG/McGovern Institute for Brain ResearchBeijing Normal UniversityBeijingChina Changping Laboratory BeijingChina State Key Laboratory of Cognitive Neuroscience and Learning IDG/McGovern Institute for Brain ResearchBeijing Normal UniversityBeijingChina State Key Laboratory of Brain and Cog

Whether adult hippocampal neurogenesis(AHN)persists in adult and aged humans continues to be extensively debated.A major question is whether the markers identified in rodents are reliable enough to reveal new neurons and the neurogenic trajectory in ***,to provide a better understanding of AHN in primates and to reveal more novel markers for distinct cell types,droplet-based single-nucleus RNA sequencing(snRNA-seq)is used to investigate the cellular heterogeneity and molecular characteristics of the hippocampi in macaques across the lifespan and in aged *** of the major cell types in the hippocampus and their expression profiles were *** dynamics of the neurogenic lineage was revealed and the diversity of astrocytes and microglia was *** the neurogenic lineage,the regulatory continuum from adult neural stem cells(NSCs)to immature and mature granule cells was investigated.A group of primate-specific markers were *** validated ETNPPL as a primate-specific NSC marker and verified STMN1 and STMN2 as immature neuron markers in ***,we illustrate a cluster of active astrocytes and microglia exhibiting proinflammatory responses in aged *** interaction analysis and the comparative investigation on published datasets and ours imply that astrocytes provide signals inducing the proliferation,quiescence and inflammation of adult NSCs at different stages and that the proinflammatory status of astrocytes probably contributes to the decrease and variability of AHN in adults and elderly individuals.

关键词： Ageing Neural stem cells

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Physical activity, cathepsin B, and cognitive health

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Trends in Molecular Medicine 2025年

作者： Yu, Qian Zhang, Zhihao Herold, Fabian Ludyga, Sebastian Kuang, Jin Chen, Yanxia Liu, Zijun Erickson, Kirk I. Goodpaster, Bret H. Cheval, Boris Pindus, Dominika M. Kramer, Arthur F. Hillman, Charles H. Liu-Ambrose, Teresa Kelley, Keith W. Moon, Hyo Youl Chen, Aiguo Zou, Liye Body-Brain-Mind Laboratory School of Psychology Shenzhen University Shenzhen 518060 China Faculty of Education University of Macau Macau China Research Group on Degenerative and Chronic Diseases Movement Faculty of Health Sciences Brandenburg University of Potsdam Potsdam 14476 Germany Department of Sport Exercise and Health University of Basel Grosse Allee 6 Basel CH-4052 Switzerland Department of Kinesiology and Community Health University of Illinois at Urbana-Champaign Urbana IL United States Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign Urbana IL United States Neuroscience Program University of Illinois at Urbana-Champaign Urbana IL United States Department of Physical Education Shanghai Jiaotong University Shanghai China Department of Neuroscience AdventHealth Research Institute Orlando FL United States AdventHealth Translational Research Institute AdventHealth Orlando FL United States Department of Sport Sciences and Physical Education Ecole Normale Supérieure Rennes Bruz France Univ Rennes École normale supérieure de Rennes Rennes F-35000 France Center for Cognitive and Brain Health Northeastern University Boston 02115 MA United States Department of Psychology Northeastern University Boston 02115 MA United States Department of Physical Therapy Movement and Rehabilitation Sciences Northeastern University Boston 02115 MA United States Djavad Mowafaghian Centre for Brain Health Vancouver Coastal Health Research Institute University of British Columbia Vancouver BC Canada Centre for Aging SMART (Solutions for Mobility Activity Rehabilitation and Technology) Vancouver Coastal Health Research Institute University of British Columbia Vancouver BC Canada Department of Physical Therapy Faculty of Medicine University of British Columbia Vancouver BC Canada Department of Pathology College of Medicine and Department of Animal Sciences College of Agricultural Consumer and Envir

Regular physical activity (PA) is beneficial for cognitive health, and cathepsin B (CTSB) – a protease released by skeletal muscle during PA – acts as a potential molecular mediator of this association. PA-induced metabolic and mechanical stress appears to increase plasma/serum CTSB levels. CTSB facilitates neurogenesis and synaptic plasticity in brain regions (e.g., hippocampus and prefrontal cortex) that support performance in specific cognitive domains including memory, learning, and executive function. However, the evidence regarding the role of PA-induced changes in CTSB as a mediator of PA-induced cognitive health in humans is mixed. To guide future research, this article identifies key factors that may explain the observed heterogeneity in the findings from human studies and proposes a PA–CTSB–cognition model. © 2024 Elsevier Ltd

关键词： brain health cognition CTSB exercise myokine

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How humor styles affect humor comprehension and appreciation: A typological approach

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Current Psychology 2023年第19期42卷 16392-16400页

作者： Wu, Ching-Lin Yen, Ying-Fan Chen, Hsueh-Chih Program of Learning Sciences National Taiwan Normal University Taipei Taiwan Institute for Research Excellence in Learning Sciences National Taiwan Normal University Taipei Taiwan Department of Educational Psychology and Counseling National Taiwan Normal University Education College Building Room 612 No. 162 Sec. 1 Heping E. Rd. Da-an District Taipei City 10610 Taiwan Chinese Language and Technology Center National Taiwan Normal University Taipei Taiwan

There have been many empirical studies on humor styles and humor comprehension and appreciation, but relatively few have directly addressed the relationship between these two topics of humor research, especially studies using a typological approach for humor styles. Therefore, the present study aimed to examine how humor styles are associated with humor comprehension and appreciation using a typological approach. The present study collected the responses of humor styles questionnaires that included ratings of comprehension and funniness of humorous pictures for 962 high school students in Taiwan. The cluster analysis result indicated that there were four humor types of participants: general humor endorsers, humor deniers, positive humor endorsers, and negative humor endorsers. The positive humor endorsers could understand the content of humor pictures better than other types of participants. The general humor endorsers found the humor pictures much funnier than the humor deniers. These findings indicate that humor styles have different associations with humor comprehension and humor appreciation. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

关键词： Humor appreciation Humor comprehension Humor style Pictorial humor

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Identifying university students’ online academic help-seeking patterns and their role in Internet self-efficacy

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Internet and Higher Education 2023年 56卷

作者： Fan, Yang-Hsin Lin, Tzung-Jin School of Learning Informatics Graduate Institute of Information and Computer Education National Taiwan Normal University Taiwan School of Learning Informatics Program of Learning Sciences National Taiwan Normal University Taiwan Institute for Research Excellence in Learning Sciences National Taiwan Normal University Taiwan

The main purposes of this study were, first, to identify Taiwanese university students’ online academic help-seeking (OAHS) patterns and further to compare their Internet self-efficacy (ISE) among the identified patterns. A total of 366 Taiwanese university students were invited to fill out two questionnaires to understand their OAHS and ISE, respectively. The results revealed that three OAHS patterns, adaptive, self-reliant, and socially-affiliated, were characterized based on the cluster analysis. The differences in the students’ various ISE dimensions among the three patterns were then compared. The adaptive students, who commonly adopted all types of OAHS behaviors, tended to be the most efficacious in the seven measured ISE dimensions. The self-reliant students, highlighting that they mainly sought help by searching for relevant information online, showed higher confidence in the ISE dimensions of "Usage," "Application," and "learning" than did the socially-affiliated students (i.e., those who tended to use formal and informal queries to seek academic help online). The socially-affiliated students only showed higher confidence in sharing online information than the self-reliant students. However, in the "Communication," "Verifying," and "Metacognition" ISE dimensions, there were no significant differences between the socially-affiliated and self-reliant students. © 2022 Elsevier Inc.

关键词： Students

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