As an important part of microwave tube, the reliability and stability of electron gun has always attracted more and more attentions of researchers. Because the working environment of microwave tube is very harsh, such...
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In this paper, a fast algorithm to obtain S parameters and mode field using the transfinite element element(TFE) method for a multi-mode output window is presented. In the proposed method, the eigenmodes of uniform el...
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An algorithm named InterOpt for optimizing operational parameters is proposed based on interpretable machine learning,and is demonstrated via optimization of shale gas *** consists of three parts:a neural network is u...
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An algorithm named InterOpt for optimizing operational parameters is proposed based on interpretable machine learning,and is demonstrated via optimization of shale gas *** consists of three parts:a neural network is used to construct an emulator of the actual drilling and hydraulic fracturing process in the vector space(i.e.,virtual environment);:the Sharpley value method in inter-pretable machine learning is applied to analyzing the impact of geological and operational parameters in each well(i.e.,single well feature impact analysis):and ensemble randomized maximum likelihood(EnRML)is conducted to optimize the operational parameters to comprehensively improve the efficiency of shale gas development and reduce the average *** the experiment,InterOpt provides different drilling and fracturing plans for each well according to its specific geological conditions,and finally achieves an average cost reduction of 9.7%for a case study with 104 wells.
The introduction of smart contracts has brought new opportunities to the development of blockchain. However, due to the potential security vulnerabilities in smart contracts, accurately identifying these vulnerabiliti...
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Modeling and simulation techniques have been playing a more and more important role in designing and developing high-performance traveling-wave tubes (TWT). Recent developments to the high-frequency circuit simulator ...
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The direct detection Doppler wind lidar, which is capable of detecting Rayleigh and Mie scattering signals synchronously and achieving the atmospheric wind field profile detection from the surface to the top of the tr...
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A single-stage multiport inverter (SSMPI)-fed motor drive, which connects dc-side energy sources to the ac motor without the application of any dc/dc power converters, offers a lightweight and highly-efficient multipl...
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In this study, we conducted a comprehensive proteomic analysis of B cells from the spleen, mesenteric lymph nodes(mLN), and peripheral blood mononuclear cells(PBMC) in a time-course model of systemic lupus erythematos...
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In this study, we conducted a comprehensive proteomic analysis of B cells from the spleen, mesenteric lymph nodes(mLN), and peripheral blood mononuclear cells(PBMC) in a time-course model of systemic lupus erythematosus(SLE) using female MRL/lpr mice. By combining fluorescence-activated cell sorting(FACS) and 4D-Data-Independent Acquisition(4D-DIA) mass spectrometry, we quantified nearly 8000 proteins, identifying significant temporal and tissue-specific proteomic changes during SLE progression. PBMC-derived B cells exhibited early proteomic alterations by Week 9, while spleen-derived B cells showed similar changes by Week 12. We identified key regulatory proteins, including BAFF, BAFFR, and NFKB2, involved in B cell survival and activation, as well as novel markers such as CD11c and CD117, which have previously been associated with other immune cells. The study high-lights the dynamic reprogramming of B cell proteomes across different tissues, with distinct contributions to SLE pathogenesis, providing valuable insights into the molecular mechanisms underlying B cell dysregulation in lupus. These findings offer potential therapeutic targets and biomarkers for SLE.
Sequential recommendation in e-commerce seeks to recommend items to users based on their past purchase preferences and has received much research attention. However, most approaches are so far restricted to modeling t...
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In allusion to many complex microwave structures with lumped electrical circuit elements, this paper proposes an algorithm to model lumped elements, such as resistance (R), inductance (L) and capacitance(C). It can be...
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