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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

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Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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Measurement of electrons from semileptonic heavy-flavor hadron decays in pp collisions at s=2.76 TeV

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Physical Review D 2015年第1期91卷 012001-012001页

作者： B. Abelev J. Adam D. Adamová M. M. Aggarwal M. Agnello A. Agostinelli N. Agrawal Z. Ahammed N. Ahmad I. Ahmed S. U. Ahn S. A. Ahn I. Aimo S. Aiola M. Ajaz A. Akindinov S. N. Alam D. Aleksandrov B. Alessandro D. Alexandre A. Alici A. Alkin J. Alme T. Alt S. Altinpinar I. Altsybeev C. Alves Garcia Prado C. Andrei A. Andronic V. Anguelov J. Anielski T. Antičić F. Antinori P. Antonioli L. Aphecetche H. Appelshäuser N. Arbor S. Arcelli N. Armesto R. Arnaldi T. Aronsson I. C. Arsene M. Arslandok A. Augustinus R. Averbeck T. C. Awes M. D. Azmi M. Bach A. Badalà Y. W. Baek S. Bagnasco R. Bailhache R. Bala A. Baldisseri F. Baltasar Dos Santos Pedrosa R. C. Baral R. Barbera F. Barile G. G. Barnaföldi L. S. Barnby V. Barret J. Bartke M. Basile N. Bastid S. Basu B. Bathen G. Batigne B. Batyunya P. C. Batzing C. Baumann I. G. Bearden H. Beck C. Bedda N. K. Behera I. Belikov F. Bellini R. Bellwied E. Belmont-Moreno R. Belmont, III V. Belyaev G. Bencedi S. Beole I. Berceanu A. Bercuci Y. Berdnikov D. Berenyi M. E. Berger R. A. Bertens D. Berzano L. Betev A. Bhasin I. R. Bhat A. K. Bhati B. Bhattacharjee J. Bhom L. Bianchi N. Bianchi C. Bianchin J. Bielčík J. Bielčíková A. Bilandzic S. Bjelogrlic F. Blanco D. Blau C. Blume F. Bock A. Bogdanov H. Bøggild M. Bogolyubsky F. V. Böhmer L. Boldizsár M. Bombara J. Book H. Borel A. Borissov F. Bossú M. Botje E. Botta S. Böttger P. Braun-Munzinger M. Bregant T. Breitner T. A. Broker T. A. Browning M. Broz E. Bruna G. E. Bruno D. Budnikov H. Buesching S. Bufalino P. Buncic O. Busch Z. Buthelezi D. Caffarri X. Cai H. Caines L. Calero Diaz A. Caliva E. Calvo Villar P. Camerini F. Carena W. Carena J. Castillo Castellanos E. A. R. Casula V. Catanescu C. Cavicchioli C. Ceballos Sanchez J. Cepila P. Cerello B. Chang S. Chapeland J. L. Charvet S. Chattopadhyay V. Chelnokov M. Cherney C. Cheshkov B. Cheynis V. Chibante Barroso D. D. Chinellato P. Chochula M. Chojnacki S. Choudhury P. Christakoglou C. H. Christensen P. Christiansen T. Chujo S. U. Chung C. Cicalo L. Cifarelli F. Cindolo J. Cleymans Lawrence Livermore National Laboratory Livermore California USA Faculty of Nuclear Sciences and Physical Engineering Czech Technical University in Prague Prague Czech Republic Nuclear Physics Institute Academy of Sciences of the Czech Republic Řežu Prahy Czech Republic Physics Department Panjab University Chandigarh India Sezione INFN Turin Italy Politecnico di Torino Turin Italy Dipartimento di Fisica e Astronomia dell’Università and Sezione INFN Bologna Italy Indian Institute of Technology Bombay (IIT) Mumbai India Variable Energy Cyclotron Centre Kolkata India Department of Physics Aligarh Muslim University Aligarh India COMSATS Institute of Information Technology (CIIT) Islamabad Pakistan Korea Institute of Science and Technology Information Daejeon South Korea Yale University New Haven Connecticut USA Institute for Theoretical and Experimental Physics Moscow Russia Russian Research Centre Kurchatov Institute Moscow Russia School of Physics and Astronomy University of Birmingham Birmingham United Kingdom Centro Fermi - Museo Storico della Fisica e Centro Studi e Ricerche “Enrico Fermi” Rome Italy Sezione INFN Bologna Italy Bogolyubov Institute for Theoretical Physics Kiev Ukraine Faculty of Engineering Bergen University College Bergen Norway Frankfurt Institute for Advanced Studies Johann Wolfgang Goethe-Universität Frankfurt Frankfurt Germany Department of Physics and Technology University of Bergen Bergen Norway V. Fock Institute for Physics St. Petersburg State University St. Petersburg Russia Universidade de São Paulo (USP) São Paulo Brazil National Institute for Physics and Nuclear Engineering Bucharest Romania Research Division and ExtreMe Matter Institute EMMI GSI Helmholtzzentrum für Schwerionenforschung Darmstadt Germany Physikalisches Institut Ruprecht-Karls-Universität Heidelberg Heidelberg Germany Institut für Kernphysik Westfälische Wilhelms-Universität Münster Münster Germany Rudjer Bošković Institute Zagreb Croatia Sezione

The pT-differential production cross section of electrons from semileptonic decays of heavy-flavor hadrons has been measured at midrapidity in proton-proton collisions at s=2.76 TeV in the transverse momentum range 0... 详细信息

关键词： PROTON-proton interactions HADRONS -- Decay CROSS sections (Nuclear physics) LARGE Hadron Collider (France & Switzerland) PERTURBATIVE quantum chromodynamics

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Erratum to: Making sense of big data in health research: towards an EU action plan

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Genome medicine 2016年第1期8卷 118页

作者： Charles Auffray Rudi Balling Inês Barroso László Bencze Mikael Benson Jay Bergeron Enrique Bernal-Delgado Niklas Blomberg Christoph Bock Ana Conesa Susanna Del Signore Christophe Delogne Peter Devilee Alberto Di Meglio Marinus Eijkemans Paul Flicek Norbert Graf Vera Grimm Henk-Jan Guchelaar Yi-Ke Guo Ivo Glynne Gut Allan Hanbury Shahid Hanif Ralf-Dieter Hilgers Ángel Honrado D Rod Hose Jeanine Houwing-Duistermaat Tim Hubbard Sophie Helen Janacek Haralampos Karanikas Tim Kievits Manfred Kohler Andreas Kremer Jerry Lanfear Thomas Lengauer Edith Maes Theo Meert Werner Müller Dörthe Nickel Peter Oledzki Bertrand Pedersen Milan Petkovic Konstantinos Pliakos Magnus Rattray Josep Redón I Màs Reinhard Schneider Thierry Sengstag Xavier Serra-Picamal Wouter Spek Lea A I Vaas Okker van Batenburg Marc Vandelaer Peter Varnai Pablo Villoslada Juan Antonio Vizcaíno John Peter Mary Wubbe Gianluigi Zanetti European Institute for Systems Biology and Medicine 1 avenue Claude Vellefaux 75010 Paris France. cauffray@***. CIRI-UMR5308 CNRS-ENS-INSERM-UCBL Université de Lyon 50 avenue Tony Garnier 69007 Lyon France. cauffray@***. Luxembourg Centre for Systems Biomedicine University of Luxembourg 7 Avenue des Hauts Fourneaux 4362 Esch-sur-Alzette Luxembourg. rudi.balling@uni.lu. Wellcome Trust Sanger Institute Wellcome Genome Campus Hinxton Cambridge CB10 1SA UK. Health Services Management Training Centre Faculty of Health and Public Services Semmelweis University Kútvölgyi út 2 1125 Budapest Hungary. Centre for Personalised Medicine Linköping University 581 85 Linköping Sweden. Translational & Bioinformatics Pfizer Inc. 300 Technology Square Cambridge MA 02139 USA. Institute for Health Sciences IACS - IIS Aragon San Juan Bosco 13 50009 Zaragoza Spain. ELIXIR Wellcome Genome Campus Hinxton Cambridge CB10 1SD UK. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Lazarettgasse 14 AKH BT25.2 1090 Vienna Austria. Department of Laboratory Medicine Medical University of Vienna Lazarettgasse 14 AKH BT25.2 1090 Vienna Austria. Max Planck Institute for Informatics Campus E1 4 66123 Saarbrücken Germany. Príncipe Felipe Research Center C/Eduardo Primo Yúfera 3 46012 Valencia Spain. University of Florida Institute of Food and Agricultural Sciences (IFAS) 2033 Mowry Road Gainesville FL 32610 USA. Bluecompanion Ltd 6 London Street (second floor) London W2 1HR UK. Technology Data & Analytics KPMG Luxembourg Société Coopérative 39 Avenue John F. Kennedy 1855 Luxembourg Luxembourg. Department of Human Genetics Department of Pathology Leiden University Medical Centre Einthovenweg 20 2333 ZC Leiden The Netherlands. Information Technology Department European Organization for Nuclear Research (CERN) 385 Route de Meyrin 1211 Geneva 23 Switzerland. Julius Center for Health Sciences and Primary Care University Medical Center

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Equation of State for Shock Compressed Xenon in the Ionization Regime:ab Initio Study

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Communications in Theoretical Physics 2012年第7期58卷 160-164页

作者：王聪顾云军陈其峰贺贤土张平 LCP Institute of Applied Physics and Computational Mathematics Laboratory for Shock Wave and Detonation Physics Research Institute of Fluid Physics Center for Applied Physics and Technology Peking University

Quantum molecular dynamic (QMD) simulations have been applied to study the thermophysical properties of liquid xenon under dynamic compressions. The equation of state (EOS) obtained from QMD calculations are corrected according to Saha equation, and contributions from atomic ionization, which are of predominance in determining the EOS at high temperature and pressure, are considered. For the pressures below 160 GPa, the necessity in accounting for the atomic ionization has been demonstrated by the Hugoniot curve, which shows excellent agreement with previous experimental measurements, and three levels of ionization have been proved to be sufficient at this stage.

关键词： equation of states quantum molecular dynamics xenon

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ESICM LIVES 2016: part two

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Intensive Care Medicine Experimental 2016年第1期4卷 205-404页

作者： S. Sivakumar F. S. Taccone K. A. Desai C. Lazaridis M. Skarzynski M. Sekhon W. Henderson D. Griesdale L. Chapple A. Deane L. Williams R. Strickland K. Lange D. Heyland M. Chapman M. J. Rowland P. Garry J. Westbrook R. Corkill C. A. Antoniades K. T. Pattinson G. Fatania A. J. Strong R. B. Myers C. M. Jermaine C. S. Robertson C. G. Rusin J. Hofmeijer L. Sondag M. C. Tjepkema-Cloostermans A. Beishuizen F. H. Bosch M. J. A. M. van Putten L. Carteron C. Patet D. Solari M. Oddo M. A. Ali C. Dias R. Almeida A. Vaz-Ferreira J. Silva E. Monteiro A. Cerejo A. P. Rocha A. A. Elsayed A. M. Abougabal B. N. Beshey K. M. Alzahaby S. Pozzebon A. Blandino Ortiz S. Cristallini O. Lheureux A. Brasseur J. L. Vincent J. Creteur M. Hravnak K. Yousef Y. Chang E. Crago R. M. Friedlander S. A. Abdelmonem S. A. Tahon T. A. Helmy H. S. Meligy F. Puig I. Dunn-Siegrist J. Pugin S. Gupta D. Govil S. Srinivasan S. J. Patel J. K. N A. Gupta D. S. Tomar M. Shafi R. Harne D. P. Arora N. Talwar S. Mazumdar E. E. Papakrivou D. Makris E. Manoulakas B. Tsolaki B. Karadodas E. Zakynthinos I. Palacios Garcia A. Diaz Martin V. Sanchez Encinares M. Pachón Ibañez J. Garnacho Montero G. Labrador T. Cebrero Cangueiro V. Poulose J. Koh J. W. Kam H. Yeter A. Kara O. Aktepe A. Topeli I. Tsolakoglou G. Intas P. Stergiannis A. A. Kolaros E. Chalari E. Athanasiadou A. Martika G. Fildisis V. Faivre C. Mengelle B. Favier D. Payen A. Poppe M. S. Winkler E. Mudersbach J. Schreiber M. L. Wruck E. Schwedhelm S. Kluge C. Zöllner T. Tavladaki A. M. Spanaki H. Dimitriou E. Kondili C. Choulaki E. Meleti D. Kafetzopoulos D. Georgopoulos G. Briassoulis A. García-de la Torre M. V. de la Torre-Prados T. Tsvetanova-Spasova P. Nuevo-Ortega C. Rueda-Molina A. Fernández-Porcel E. Camara-Sola L. Salido-Díaz A. García-Alcántara D. E. Meleti B. Suberviola J. Riera L. Rellan M. Sanchez J. C. Robles E. Lopez R. Vicente E. Miñambres M. Santibañez M. Le Guen J. Moore N. Mason M. Windpassinger O. Plattner E. Mascha D. I. Sessler Outcomes research U. Melia J. Fontanet J. P. van den Berg M. Baylor College of Medicine Neurology/Neurocritical Care Houston USA Erasmus Hospital Intensive Care Medicine Brussels Belgium Centre Hospitalier Régional Orléans Réaimation Médicale Orléans France University of British Columbia Vancouver Canada University of Adelaide Discipline of Acute Care Medicine Adelaide Australia Royal Adelaide Hospital Intensive Care Adelaide Australia Griffith University Menzies Health Institute of Queensland Gold Coast Australia University of Adelaide Discipline of Medicine Adelaide Australia Kingston General Hospital Clinical Evaluation Research Unit Kingston Canada University of Oxford Nuffield Department of Clinical Neurosciences Oxford UK Oxford University Hospitals NHS Foundation Trust Neurosciences Intensive Care Unit Oxford UK King’s College Hospital Department of Neurosurgery London UK King’ College London Institute of Psychiatry Psychology and Neuroscience Department of Clinical Neuroscience London UK Rice University Computer Science Houston USA Baylor College of Medicine Neurosurgery Houston USA Baylor College of Medicine Pediatric Cardiology Houston USA University of Twente Clinical Neurophysiology Enschede Netherlands Rijnstate Hospital Neurology Arnhem Netherlands Medical Spectrum Twente Clinical Neurophysiology Enschede Netherlands Medical Spectrum Twente Intensive Care Enschede Netherlands Rijnstate Hospital Intensive Care Arnhem Netherlands CHUV Department of Intensive Care Medicine Neuroscience Critical Care Research Group Lausanne Switzerland Aga Khan University Hospital Anaesthesiology Karachi Pakistan Centro Hospitalar São João Intensive Care Porto Portugal Faculty of Medicine University of Porto Medicine Porto Portugal Faculdade de Ciências Universidade do Porto Departamento de Matemática Porto Portugal Centro de Matemática Universidade do Porto Porto Portugal The Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine Zaragoza Spain Centro Hospitalar

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Directed ratchet transport in granular chains

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Physical Review E 2013年第5期88卷 052202-052202页

作者： V. Berardi J. Lydon P. G. Kevrekidis C. Daraio R. Carretero-González Nonlinear Dynamical Systems Group† Computational Science Research Center‡ and Department of Mathematics and Statistics San Diego State University San Diego California 92182-7720 USA Graduate Aeronautical Laboratories (GALCIT) and Department of Applied Physics California Institute of Technology Pasadena California 91125 USA Department of Mechanical and Process Engineering Swiss Federal Institute of Technology (ETH) Zürich Switzerland Department of Mathematics and Statistics University of Massachusetts Amherst Massachusetts 01003-4515 USA

Directed-ratchet transport (DRT) in a one-dimensional lattice of spherical beads, which serves as a prototype for granular chains, is investigated. We consider a system where the trajectory of the central bead is prescribed by a biharmonic forcing function with broken time-reversal symmetry. By comparing the mean integrated force of beads equidistant from the forcing bead, two distinct types of directed transport can be observed—spatial and temporal DRT. Based on the value of the frequency of the forcing function relative to the cutoff frequency, the system can be categorized by the presence and magnitude of each type of DRT. Furthermore, we investigate and quantify how varying additional parameters such as the biharmonic weight affects DRT velocity and magnitude. Finally, friction is introduced into the system and is found to significantly inhibit spatial DRT. In fact, for sufficiently low forcing frequencies, the friction may even induce a switching of the DRT direction.

关键词： GRANULAR materials RATCHETS PROTOTYPES LATTICE theory BIHARMONIC equations BROKEN symmetry (Physics)

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An approach to absence epileptic seizures detection using Approximate Entropy

An approach to absence epileptic seizures detection using Ap...

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Annual International Conference of the IEEE Engineering in Medicine and Biology Society

作者： Giorgos Giannakakis Vangelis Sakkalis Matthew Pediaditis Christina Farmaki Pelagia Vorgia Manolis Tsiknakis Computational Medicine Laboratory (CML) Institute of Computer Science (ICS) Foundation of Research and Technology Heraklion (FORTH) CML-ICS FORTH University of Crete Department of Mother and Child Health Faculty of Medicine FORTH CML-ICS and with the Department of Applied Informatics and Multimedia Technological Educational Institute of Crete

ISBN: (纸本)9781457702150

Epilepsy is one of the most common chronic neurological diseases and the most common neurological chronic disease of childhood. The electroencephalogram (EEG) signal provides significant information neurologists take into consideration in the investigation and analysis of epileptic seizures. The Approximate Entropy (ApEn) is a formulated statistical parameter commonly used to quantify the regularity of a time series data of physiological signals. In this paper ApEn is used in order to detect the onset of epileptic seizures. The results show that the method provides promising results towards efficient detection of onset and ending of seizures, based on analyzing the corresponding EEG signals. ApEn parameters affect the method's behavior, suggesting that a more detailed study and a consistent methodology of their determination should be established. A preliminary analysis for the proper determination of these parameters is performed towards improving the results.

关键词： epileptic seizure time series data Electroencephalography Epilepsy entropy Approximate signals Seizures statistical parameters

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Aneurysm Intraluminal Thrombus Compressibility Estimated invivo Using Electrocardiographically Gated Computed Tomography: A Feasibility Study

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EJVES Extra 2013年第1期26卷 e4页

作者： Kontopodis, N. Metaxa, E. Pagonidis, K. Georgakarakos, E. Papaharilaou, Y. Ioannou, C.V. Vascular Surgery Department University of Crete Medical School 711 10 Heraklion Crete PO Box 1352 Greece Institute of Applied and Computational Mathematics Foundation for Research and Technology - Hellas Heraklion Greece Asklipios Diagnostic Radiology Center Heraklion Greece Vascular Surgery Department Demokritus University of Thrace Medical School Alexandroupolis Greece

Introduction: We attempt to investigate if the mechanical properties of an intraluminal thrombus (ILT) could be assessed non-invasively through modern imaging techniques. Thrombus compressibility and deformation are evaluated invivo. Report: Five patients underwent electrocardiographically (ECG) gated computed tomography scan during surveillance of their abdominal aortic aneurysm (AAA). ILT volumes and cross-sectional areas during peak systole and end diastole were recorded and found to remain constant. Discussion: ILT elastic behaviour can be estimated non-invasively. Under physiologic arterial pressure, an ILT is incompressible and does not deform longitudinally. © 2013 European Society for Vascular Surgery.

关键词： ECG-gated CT ILT compressibility ILT mechanical properties

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The open connectome project data cluster: Scalable analysis and vision for high-throughput neuroscience

The open connectome project data cluster: Scalable analysis ...

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25th International Conference on Scientific and Statistical Database Management, SSDBM 2013

作者： Burns, Randal Roncal, William Gray Kleissas, Dean Lillaney, Kunal Manavalan, Priya Perlman, Eric Berger, Daniel R. Bock, Davi D. Chung, Kwanghun Grosenick, Logan Kasthuri, Narayanan Weiler, Nicholas C. Deisseroth, Karl Kazhdan, Michael Lichtman, Jeff Reid, R. Clay Smith, Stephen J. Szalay, Alexander S. Vogelstein, Joshua T. Vogelstein, R. Jacob Department of Computer Science Institute for Data Intensive Engineering and Science Johns Hopkins University United States Applied Physics Laboratory Johns Hopkins University United States Department of Statistical Science and Mathematics Institute for Brain Science Duke University United States Janelia Farm Research Campus Howard Hughes Medical Institute United States Department of Molecular and Cellular Biology Harvard University United States Department of Computational Neuroscience Massachusetts Institute of Technology United States Allen Institute for Brain Science United States Department of Physics and Astronomy Institute for Data Intensive Engineering and Science Johns Hopkins University United States Department of Bioengineering Stanford University United States Department of Molecular and Cellular Physiology Stan- Ford University United States

ISBN: (纸本)9781450319218

We describe a scalable database cluster for the spatial analysis and annotation of high-throughput brain imaging data, initially for 3-d electron microscopy image stacks, but for time-series and multi-channel data as well. The system was designed primarily for workloads that build connectomes- neural connectivity maps of the brain-using the parallel execution of computer vision algorithms on high-performance compute clusters. These services and open-science data sets are publicly available at ***. The system design inherits much from NoSQL scale-out and data-intensive computing architectures. We distribute data to cluster nodes by partitioning a spatial index. We direct I/O to different systems-reads to parallel disk arrays and writes to solid-state storage-to avoid I/O interference and maximize throughput. All programming interfaces are RESTful Web services, which are simple and stateless, improving scalability and usability. We include a performance evaluation of the production system, highlighting the effectiveness of spatial data organization. Copyright © 2013 ACM.

关键词： Digital storage

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