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Nature Water 2025年 1-11页

作者： Aßmann, Eva Greiner, Timo Richard, Hugues Wade, Matthew Agrawal, Shelesh Amman, Fabian Böttcher, Sindy Lackner, Susanne Landthaler, Markus Mangul, Serghei Munteanu, Viorel Psomopoulos, Fotis Smith, Maureen Trofimova, Maria Ullrich, Alexander von Kleist, Max Wyler, Emanuel Hölzer, Martin Irrgang, Christopher Centre for Artificial Intelligence in Public Health Research (ZKI-PH) Robert Koch Institute Berlin Germany Genome Competence Center (MF1) Robert Koch Institute Berlin Germany Department of Infectious Disease Epidemiology Robert Koch Institute Berlin Germany Chief Data Officer Group UK Health Security Agency London United Kingdom Chair of Water and Environmental Biotechnology Institute IWAR Department of Civil and Environmental Engineering Sciences Technical University of Darmstadt Darmstadt Germany CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria Institute for Hygiene and Applied Immunology Medical University of Vienna Vienna Austria Gastroenteritis and Hepatitis Pathogens and Enteroviruses (FG15) Robert Koch Institute Berlin Germany Berlin Institute for Medical Systems Biology Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) Berlin Germany Institute for Biology Humboldt-Universität zu Berlin Berlin Germany Titus Family Department of Clinical Pharmacy USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences University of Southern California Los Angeles CA United States Department of Biological and Morphofunctional Sciences College of Medicine and Biological Sciences Stefan cel Mare University of Suceava Suceava Romania Department of Computers Informatics and Microelectronics Technical University of Moldova Chisinau Moldova Institute of Applied Biosciences Center for Research and Technology Hellas Thessaloniki Greece Systems Medicine of Infectious Disease (P5) Robert Koch Institute Berlin Germany Department of Mathematics and Computer Science Freie Universität Berlin Berlin Germany

Wastewater-based epidemiology (WBE) has proven to be a valuable tool for monitoring the evolution and spread of global health threats, from pathogens to antimicrobial resistances. Throughout the COVID-19 pandemic, multiple wastewater surveillance programmes have advanced statistical and machine learning methods for detecting pathogens from wastewater sequencing data and correlating measured targets with the represented population to infer meaningful conclusions for public health. Integrating contextual data can account for measurement uncertainties across the WBE workflow that affect the reliability of analyses. However, the broader availability and harmonization of data are major obstacles to method development. Here we review the benefits and limitations of wastewater-related data streams, highlighting the potential of machine learning to leverage these streams for normalization and other WBE applications. We emphasize the relevance of developing global frameworks for integrating WBE with other health surveillance systems and discuss next steps to address current and foreseeable challenges for robust and interpretable machine learning-enhanced WBE. © Springer Nature Limited 2025.

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Benchmarking quality-dependent and cost-sensitive score-level multimodal biometric fusion algorithms

arXiv

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arXiv 2021年

作者： Poh, Norman Bourlai, Thirimachos Kittler, Josef Allano, Lorene Alonso-Fernandez, Fernando Ambekar, Onkar Baker, John Dorizzi, Bernadette Fatukasi, Omolara Fierrez, Julian Ganster, Harald Ortega-Garcia, Javier Maurer, Donald Salah, Albert Ali Scheidat, Tobias Vielhauer, Claus Centre for Vision Speech and Signal Processing School of Electronics and Physical Sciences University of Surrey Guildford SurreyGU2 7XH United Kingdom Biometrics Center Lane Department of Computer Science and Electrical Engineering College of Engineering and Mineral Resources West Virginia University MorgantownWV26506-6109 United States Institut Telecom Telecom and Management SudParis Evry91011 France Biometric Recognition Group – ATVS Escuela Politecnica Superior Universidad Autonoma de Madrid Madrid28049 Spain Amsterdam1098 XG Netherlands Applied Physics Laboratory Johns Hopkins University LaurelMD20723 United States Electronics and Physics Department Institut Telecom Telecom and Management SudParis Evry91011 France Institute of Digital Image Processing Joanneum Research Graz8010 Austria ISLA-ISIS University of Amsterdam Amsterdam1098 XG Netherlands Department of Informatics and Media Brandenburg University of Applied Sciences Brandenburg an der HavelD-14770 Germany Research Group Multimedia and Security Department of Technical and Business Information Systems Faculty of Computer Science Otto-von-Guericke-University of Magdeburg MagdeburgD-39106 Germany

Automatically verifying the identity of a person by means of biometrics (e.g., face and fingerprint) is an important application in our day-to-day activities such as accessing banking services and security control in airports. To increase the system reliability, several biometric devices are often used. Such a combined system is known as a multimodal biometric system. This paper reports a benchmarking study carried out within the framework of the BioSecure DS2 (Access Control) evaluation campaign organized by the University of Surrey, involving face, fingerprint, and iris biometrics for person authentication, targeting the application of physical access control in a medium-size establishment with some 500 persons. While multimodal biometrics is a well-investigated subject in the literature, there exists no benchmark for a fusion algorithm comparison. Working towards this goal, we designed two sets of experiments: quality-dependent and cost-sensitive evaluation. The quality-dependent evaluation aims at assessing how well fusion algorithms can perform under changing quality of raw biometric images principally due to change of devices. The cost-sensitive evaluation, on the other hand, investigates how well a fusion algorithm can perform given restricted computation and in the presence of software and hardware failures, resulting in errors such as failure-to-acquire and failure-to-match. Since multiple capturing devices are available, a fusion algorithm should be able to handle this nonideal but nevertheless realistic scenario. In both evaluations, each fusion algorithm is provided with scores from each biometric comparison subsystem as well as the quality measures of both the template and the query data. The response to the call of the evaluation campaign proved very encouraging, with the submission of 22 fusion systems. To the best of our knowledge, this campaign is the first attempt to benchmark quality-based multimodal fusion algorithms. In the presence of changing

关键词： Benchmarking

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Multimodal Explainable Artificial Intelligence for Prognostic Stratification of Glioblastoma Patients

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Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2025年第9期38卷 100797页

作者： Bhakti Baheti Sunny Rai Shubham Innani Garv Mehdiratta W Robert Bell Sharath Chandra Guntuku MacLean P Nasrallah Spyridon Bakas Division of Computational Pathology Department of Pathology and Laboratory Medicine Indiana University School of Medicine Indianapolis IN USA Indiana University Melvin and Bren Simon Comprehensive Cancer Center Indianapolis IN USA. Department of Computer and Information Science School of Engineering and Applied Science University of Pennsylvania Philadelphia PA USA Leonard Davis Institute of Health Economics University of Pennsylvania Philadelphia PA USA. Division of Computational Pathology Department of Pathology and Laboratory Medicine Indiana University School of Medicine Indianapolis IN USA. School of Arts and Sciences University of Pennsylvania Philadelphia PA USA. Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Indiana University Melvin and Bren Simon Comprehensive Cancer Center Indianapolis IN USA Department of Neurological Surgery Indiana University School of Medicine Indianapolis IN USA Department of Computer Science Luddy School of Informatics Computing and Engineering Indiana University Indianapolis IN United States. Electronic address: spbakas@iu.edu.

Glioblastoma is the most common and aggressive malignant adult tumor of the central nervous system, with a grim prognosis and heterogeneous morphologic and molecular profiles. Since the adoption of the current standard-of-care treatment in 2005, no substantial prognostic improvement has been noticed. In this study, we seek the identification of prognostically relevant glioblastoma characteristics from routinely acquired hematoxylin and eosin-stained whole slide images (WSI) and clinical data, that integrated via advanced computational methods could yield improved patient prognostic stratification and hence optimize clinical decision making and patient management. The proposed WSI analysis capitalizes on a comprehensive curation of apparent artifactual content and an interpretability mechanism via a weakly supervised attention-based multiple- instance learning approach that further utilizes clustering to constrain the search space. Patterns automatically identified by our approach as of high prognostic value classify each WSI as representative of short or long survivors. Further assessments of the prognostic relevance of the associated clinical patient data are performed both in isolation and in an integrated manner, using XGBoost and shapley additive explanations (SHAP). The multimodal integration of WSI with clinical data yields enhanced stratification performance when compared with using either one of the modalities. Identifying tumor morphological and clinical patterns associated with short and long survival will enable the clinical neuropathologist to provide additional relevant prognostic information to the treating team and suggest avenues of biological investigation for further understanding and potentially treating glioblastoma.

关键词： Glioblastoma Histopathology Interpretability Multimodal Prognosis Survival XGBoost

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Improve cybersecurity of C-ITS Road Side Infrastructure Installations: the SerIoT - Secure and Safe IoT approach

Improve cybersecurity of C-ITS Road Side Infrastructure Inst...

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International Conference on Connected Vehicles and Expo (ICCVE)

作者： Alexander Frötscher Bernhard Monschiebl Anastasios Drosou Erol Gelenbe Martin J. Reed Mays Al-Naday Technologies and Services for Mobility Austriatech GmbH. Vienna Austria Information Technologies Institute Centre for Reasearch & Technology Hellas Thessaloniki Greece Institute of Theoretical and Applied Informatics Polish Academy of Sciences Gliwice Poland School of Computer Science and Electronic Engineering University of Essex Essex United Kingdom

Cooperative Intelligent Transport Systems (C-ITS) need to be secured as it is deployed on roads in Europe. While some aspects of the communication security are secured others could still need improvement. SerIoT as a security project for the internet of things and offers various security mechanisms from the IoT domain which could be beneficial for C-ITS. Such security mechanisms contain a software defined network, the usage of honeypots and several mechanisms to analyze, monitor and mitigate threats on the system. Therefore C-ITS will benefit tremendously of the functionalities from these security mechanisms designed to cope with large attack surfaces and high network traffic found in IoT environments. To enable these technologies, modules developed within SerIoT are planned to be integrated into the Road Side ITS station. The station will also be connected to SerIoT SDN routers providing security for the station from malicious vehicles and the network.

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Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients

IEEE Transactions on Technology and Society

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IEEE Transactions on Technology and Society 2022年第4期3卷 272-289页

作者： Allahabadi, Himanshi Amann, Julia Balot, Isabelle Beretta, Andrea Binkley, Charles Bozenhard, Jonas Bruneault, Frederick Brusseau, James Candemir, Sema Cappellini, Luca Alessandro Chakraborty, Subrata Cherciu, Nicoleta Cociancig, Christina Coffee, Megan Ek, Irene Espinosa-Leal, Leonardo Farina, Davide Fieux-Castagnet, Genevieve Frauenfelder, Thomas Gallucci, Alessio Giuliani, Guya Golda, Adam Van Halem, Irmhild Hildt, Elisabeth Holm, Sune Kararigas, Georgios Krier, Sebastien A. Kuhne, Ulrich Lizzi, Francesca Madai, Vince I. Markus, Aniek F. Masis, Serg Mathez, Emilie Wiinblad Mureddu, Francesco Neri, Emanuele Osika, Walter Ozols, Matiss Panigutti, Cecilia Parent, Brendan Pratesi, Francesca Moreno-Sanchez, Pedro A. Sartor, Giovanni Savardi, Mattia Signoroni, Alberto Sormunen, Hanna-Maria Spezzatti, Andy Srivastava, Adarsh Stephansen, Annette F. Theng, Lau Bee Tithi, Jesmin Jahan Tuominen, Jarno Umbrello, Steven Vaccher, Filippo Vetter, Dennis Westerlund, Magnus Wurth, Renee Zicari, Roberto V. Ey Netherlands Enterprise Intelligence Department Amsterdam1083 HP Netherlands Eth Zurich Health Ethics and Policy Lab Department of Health Sciences and Technology Zürich8092 Switzerland Center for Diplomatic and Strategic Studies Postgraduate Studies in Diplomacy and International Relations Paris75015 France Pisa56124 Italy Hackensack Meridian Health Bioethics Center EdisonNJ08820 United States University of Oxford Faculty of Philosophy OxfordOX2 6GG United Kingdom Collège André- Laurendeau Philosophie Department MontrealQCH8N 2J4 Canada Université du Québec À Montréal École des Médias MontrealQCH2L 2C4 Canada Pace University Philosophy Department New YorkNY10038 United States The Ohio State University Wexner Medical Center Department of Radiology ColumbusOH43210 United States Humanitas Research Hospital Department of Radiology Milan20089 Italy Humanitas University Department of Biomedical Sciences Milan20089 Italy University of New England Faculty of Science Agriculture Business and Law ArmidaleNSW2351 Australia University of Technology Sydney Faculty of Engineering and Information Technology SydneyNSW2007 Australia Scuola Superiore Sant'Anna European Centre of Excellence on the Regulation of Robotics and Ai Pisa56127 Italy University of Bremen Group of Computer Architecture Bremen28359 Germany New York University Grossman School of Medicine Division of Infectious Diseases and Immunology Department of Medicine New YorkNY10016 United States Digital Institute Ai Research Section Stockholm16731 Sweden Arcada University of Applied Sciences Department of Business Management and Analytics Helsinki00550 Finland University of Brescia Radiological Sciences and Public Health Department of Medical and Surgical Specialties Brescia25121 Italy Sncf Reseau Sa Ethique Groupe La Plaine93418 France Institute of Diagnostic and Interventional Radiology University Hospital Zurich Zürich8091 Switzerland Eindhoven University of Tech

This article's main contributions are twofold: 1) to demonstrate how to apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does 'trustworthy AI' mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays. It has been experimentally deployed in the radiology department of the ASST Spedali Civili clinic in Brescia, Italy, since December 2020 during pandemic time. The methodology we have applied for our post-hoc assessment, called Z-Inspection®, uses sociotechnical scenarios to identify ethical, technical, and domain-specific issues in the use of the AI system in the context of the pandemic. © 2020 IEEE.

关键词： COVID-19

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Portable Acceleration of CMS Computing Workflows with Coprocessors as a Service

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Computing and Software for Big Science 2024年第1期8卷 1-36页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Hussain, P.S. Jeitler, M. Krammer, N. Li, A. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Mechelen, P. Van Bols, E.S. D’Hondt, J. Dansana, S. De Moor, A. Delcourt, M. Faham, H. El Lowette, S. Makarenko, I. Müller, D. Sahasransu, A.R. Tavernier, S. Tytgat, M. Onsem, G. P. Van Putte, S. Van Vannerom, D. Clerbaux, B. Das, A.K. De Lentdecker, G. Favart, L. Gianneios, P. Hohov, D. Jaramillo, J. Khalilzadeh, A. Khan, F.A. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Thomas, L. Bemden, M. Vanden Velde, C. Vander Vanlaer, P. De Coen, M. Dobur, D. Hong, Y. Knolle, J. Lambrecht, L. Mestdach, G. Amarilo, K. Mota Rendón, C. Samalan, A. Skovpen, K. Bossche, N. Van Den Linden, J. van der Wezenbeek, L. Benecke, A. Bethani, A. Bruno, G. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sh. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. De Oliveira, T. Menezes Moraes, A. Teles, P. Rebello Soeiro, M. Júnior, W. L. Aldá Pereira, M. Alves Gallo Filho, M. Barroso Ferreira Malbouisson, H. Brandao Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. De Souza, S. Fonseca De Souza, R. Gomes Martins, J. Herrera, C. Mora Mundim, L. Nogima, H. Pinheiro, J.P. Santoro, A. Sznajder, A. Thiel, M. Pereira, A. Vilela Bernardes, C.A. Calligaris, L. Tomei, T. R. Fernandez Perez Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Javaid, T. Yuan, L. Hu, Z. Liu, J. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Sharma, R. Song, J.N. Tao, J. Wang, C. Wang, J. Wang, Z. Zhang, H. Agapitos Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-sen University Guangzhou China University of Science and Technology of China Hefei China Nanjing Normal University Nanjing China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) - Fudan University Shanghai China Zhejiang University Hangzhou Zhejiang China Universidad de Los Andes Bogota Colombia Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia Faculty of Science University of Split Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysic

Computing demands for large scientific experiments, such as the CMS experiment at the CERN LHC, will increase dramatically in the next decades. To complement the future performance increases of software running on central processing units (CPUs), explorations of coprocessor usage in data processing hold great potential and interest. Coprocessors are a class of computer processors that supplement CPUs, often improving the execution of certain functions due to architectural design choices. We explore the approach of Services for Optimized Network Inference on Coprocessors (SONIC) and study the deployment of this as-a-service approach in large-scale data processing. In the studies, we take a data processing workflow of the CMS experiment and run the main workflow on CPUs, while offloading several machine learning (ML) inference tasks onto either remote or local coprocessors, specifically graphics processing units (GPUs). With experiments performed at Google Cloud, the Purdue Tier-2 computing center, and combinations of the two, we demonstrate the acceleration of these ML algorithms individually on coprocessors and the corresponding throughput improvement for the entire workflow. This approach can be easily generalized to different types of coprocessors and deployed on local CPUs without decreasing the throughput performance. We emphasize that the SONIC approach enables high coprocessor usage and enables the portability to run workflows on different types of coprocessors. © The Author(s) 2024.

关键词： CMS Machine learning Offline and computing

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An Early Stage Researcher's Primer on Systems Medicine Terminology

Network and Systems Medicine

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Network and Systems Medicine 2021年第1期4卷 2-50页

作者： Zanin, Massimiliano Aitya, Nadim A.A. Basilio, José Baumbach, Jan Benis, Arriel Behera, Chandan K. Bucholc, Magda Castiglione, Filippo Chouvarda, Ioanna Comte, Blandine Dao, Tien-Tuan Ding, Xuemei Pujos-Guillot, Estelle Filipovic, Nenad Finn, David P. Glass, David H. Harel, Nissim Iesmantas, Tomas Ivanoska, Ilinka Joshi, Alok Boudjeltia, Karim Zouaoui Kaoui, Badr Kaur, Daman Maguire, Liam P. McClean, Paula L. McCombe, Niamh De Miranda, João Luís Moisescu, Mihnea Alexandru Pappalardo, Francesco Polster, Annikka Prasad, Girijesh Rozman, Damjana Sacala, Ioan Sanchez-Bornot, Jose M. Schmid, Johannes A. Sharp, Trevor Solé-Casals, Jordi Spiwok, Vojtěch Spyrou, George M. Stalidzans, Egils Stres, Blaa Sustersic, Tijana Symeonidis, Ioannis Tieri, Paolo Todd, Stephen Van Steen, Kristel Veneva, Milena Wang, Da-Hui Wang, Haiying Wang, Hui Watterson, Steven Wong-Lin, Kongfatt Yang, Su Zou, Xin Schmidt, Harald H.H.W. Centro de Tecnología Biomédica Universidad Politécnica de Madrid Madrid Spain Intelligent Systems Research Centre School of Computing Engineering and Intelligent Systems Ulster University Ulster United Kingdom Center for Physiology and Pharmacology Institute of Vascular Biology and Thrombosis Research Medical University of Vienna Vienna Austria TUM School of Life Sciences Weihenstephan Technical University of Munich Freising Germany Holon Israel CNR National Research Council IAC Institute for Applied Computing Rome Italy Lab of Computing Medical Informatics and Biomedical Imaging Technologies School of Medicine Aristotle University of Thessaloniki Thessaloniki Greece Université Clermont Auvergne INRAE UNH Plateforme d'Exploration du Métabolisme MetaboHUB Clermont Clermont-Ferrand France Université de Technologie de Compiègne Compiègne France Labex MS2T Control of Technological Systems-of-Systems CNRS and Université de Technologie de Compiègne Compiègne France Faculty of Engineering University of Kragujevac Kragujevac Serbia Kragujevac Serbia Steinbeis Advanced Risk Technologies Institute Doo Kragujevac Kragujevac Serbia Pharmacology and Therapeutics School of Medicine Galway Neuroscience Centre National University of Ireland Galway Ireland School of Computing Ulster University Ulster United Kingdom Holon Israel Department of Mathematics and Natural Sciences Kaunas University of Technology Kaunas Lithuania Faculty of Computer Science and Engineering Ss. Cyril and Methodius University Skopje Macedonia Medicine Faculty Université Libre de Bruxelles CHU de Charleroi Charleroi Belgium Northern Ireland Centre for Stratified Medicine Biomedical Sciences Research Institute Ulster University Ulster United Kingdom Escola Superior de Tecnologia e Gestão Instituto Politécnico de Portalegre Portalegre Portugal Instituto Superior Técnico Universidade de Lisboa Lisboa Portugal Faculty of Automatic Control and Computers University Politehnica of B

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references. Results: This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic. © Massimiliano Zanin et al., 2021;Published by Mary Ann Liebert, Inc. 2021.

关键词： Semantics

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Measurement of the τ lepton polarization in Z boson decays in proton-proton collisions at (Formula presented.)

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Journal of High Energy Physics 2024年第1期2024卷 1-54页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Hussain, P.S. Jeitler, M. Krammer, N. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Van Mechelen, P. Bols, E.S. D’Hondt, J. Dansana, S. De Moor, A. Delcourt, M. El Faham, H. Lowette, S. Makarenko, I. Müller, D. Sahasransu, A.R. Tavernier, S. Tytgat, M. Van Putte, S. Vannerom, D. Clerbaux, B. De Lentdecker, G. Favart, L. Hohov, D. Jaramillo, J. Khalilzadeh, A. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Pétré, L. Postiau, N. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. De Coen, M. Dobur, D. Hong, Y. Knolle, J. Lambrecht, L. Mestdach, G. Rendón, C. Samalan, A. Skovpen, K. Van Den Bossche, N. Wezenbeek, L. Benecke, A. Bruno, G. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sa. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. Menezes De Oliveira, T. Moraes, A. Rebello Teles, P. Soeiro, M. Aldá Júnior, W.L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Fonseca De Souza, S. Martins, J. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Guo, Q. Javaid, T. Mittal, M. Yuan, L. Bauer, G. Hu, Z. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Monti, F. Sharma, R. Song, J.N. Tao, J. Wang, C. Wang, J. Wang, Z. Zhang, H. Agapitos, A. Ban, Y. Lev Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-Sen University Guangzhou China University of Science and Technology of China Hefei China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) — Fudan University Shanghai China Zhejiang University Zhejiang Hangzhou China Universidad de Los Andes Bogota Colombia Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia University of Split Faculty of Science Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysics Tallinn Estonia Department of Physics

The polarization of τ leptons is measured using leptonic and hadronic τ lepton decays in Z → τ+ τ− events in proton-proton collisions at (Formula presented.) recorded by CMS at the CERN LHC with an integrated lum... 详细信息

The polarization of τ leptons is measured using leptonic and hadronic τ lepton decays in Z → τ⁺ τ⁻ events in proton-proton collisions at (Formula presented.) recorded by CMS at the CERN LHC with an integrated luminosity of 36.3 fb⁻¹. The measured τ⁻ lepton polarization at the Z boson mass pole is P_τ(Z) = −0.144 ± 0.006 (stat) ± 0.014 (syst) = −0.144 ± 0.015, in good agreement with the measurement of the τ lepton asymmetry parameter of A_τ = 0.1439 ± 0.0043 = − P_τ(Z) at LEP. The τ lepton polarization depends on the ratio of the vector to axial-vector couplings of the τ leptons in the neutral current expression, and thus on the effective weak mixing angle sin² θWeff , independently of the Z boson production mechanism. The obtained value sin² θWeff = 0.2319 ± 0.0008(stat) ± 0.0018(syst) = 0.2319 ± 0.0019 is in good agreement with measurements at e⁺ e⁻ colliders. [Figure not available: see fulltext.]. © 2024, The Author(s).

关键词： Hadron-Hadron Scattering Tau Physics

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Search for W′ bosons decaying to a top and a bottom quark in leptonic final states in proton-proton collisions at s = 13 TeV

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Journal of High Energy Physics 2024年第5期2024卷 1-51页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Hussain, P.S. Jeitler, M. Krammer, N. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Van Mechelen, P. Bols, E.S. D’hondt, J. Dansana, S. De Moor, A. Delcourt, M. El Faham, H. Lowette, S. Makarenko, I. Müller, D. Sahasransu, A.R. Tavernier, S. Tytgat, M. Van Putte, S. Vannerom, D. Clerbaux, B. De Lentdecker, G. Favart, L. Hohov, D. Jaramillo, J. Khalilzadeh, A. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Pétré, L. Postiau, N. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. De Coen, M. Dobur, D. Hong, Y. Knolle, J. Lambrecht, L. Mestdach, G. Rendón, C. Samalan, A. Skovpen, K. Van Den Bossche, N. Wezenbeek, L. Benecke, A. Bruno, G. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sa. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. Menezes De Oliveira, T. Moraes, A. Rebello Teles, P. Soeiro, M. Aldá Júnior, W.L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Fonseca De Souza, S. Martins, J. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Guo, Q. Javaid, T. Mittal, M. Yuan, L. Bauer, G. Hu, Z. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Monti, F. Sharma, R. Song, J.N. Tao, J. Wang, C. Wang, J. Wang, Z. Zhang, H. Agapitos, A. Ban, Y. Lev Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-Sen University Guangzhou China University of Science and Technology of China Hefei China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) — Fudan University Shanghai China Zhejiang University Zhejiang Hangzhou China Universidad de Los Andes Bogota Colombia Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia University of Split Faculty of Science Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysics Tallinn Estonia Department of Physics

A search for W′ bosons decaying to a top and a bottom quark in final states including an electron or a muon is performed with the CMS detector at the LHC. The analyzed data correspond to an integrated luminosity of 138 fb⁻¹ of proton-proton collisions at a center-of-mass energy of 13 TeV. Good agreement with the standard model expectation is observed and no evidence for the existence of the W′ boson is found over the mass range examined. The largest observed deviation from the standard model expectation is found for a W′ boson mass (mW_′) hypothesis of 3.8 TeV with a relative decay width of 1%, with a local (global) significance of 2.6 (2.0) standard deviations. Upper limits on the production cross sections of W′ bosons decaying to a top and a bottom quark are set. Left- and right-handed W′ bosons with mW_′ below 3.9 and 4.3 TeV, respectively, are excluded at the 95% confidence level, under the assumption that the new particle has a narrow decay width. Limits are also set for relative decay widths up to 30%. © The Author(s) 2024.

关键词： Beyond Standard Model Hadron-Hadron Scattering Vector Boson Production

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Measurement of the double-differential inclusive jet cross section in proton-proton collisions at s = 5.02 TeV

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Journal of High Energy Physics 2025年第1期2025卷 1-49页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Hussain, P.S. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Kello, T. Van Mechelen, P. Bols, E.S. D’Hondt, J. De Moor, A. Delcourt, M. El Faham, H. Lowette, S. Makarenko, I. Morton, A. Müller, D. Sahasransu, A.R. Tavernier, S. Van Putte, S. Vannerom, D. Clerbaux, B. Dansana, S. De Lentdecker, G. Favart, L. Hohov, D. Jaramillo, J. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Pétré, L. Postiau, N. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. De Coen, M. Dobur, D. Knolle, J. Lambrecht, L. Mestdach, G. Rendón, C. Samalan, A. Skovpen, K. Tytgat, M. Van Den Bossche, N. Vermassen, B. Wezenbeek, L. Benecke, A. Bruno, G. Bury, F. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sa. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Vischia, P. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. Moraes, A. Rebello Teles, P. Aldá Júnior, W.L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Dos Santos Sousa, V. Fonseca De Souza, S. Martins, J. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Guo, Q. Javaid, T. Mittal, M. Yuan, L. Bauer, G. Hu, Z. Lezki, S. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Monti, F. Sharma, R. Song, J.N. Tao, J. Wang, J. Zhang, H. Aga Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-Sen University Guangzhou China University of Science and Technology of China Hefei China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) — Fudan University Shanghai China Zhejiang University Zhejiang Hangzhou China Universidad de Los Andes Bogota Venezuela Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia University of Split Faculty of Science Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysics Tallinn Estonia Department of Physics

The inclusive jet cross section is measured as a function of jet transverse momentum pT and rapidity y. The measurement is performed using proton-proton collision data at s = 5.02 TeV, recorded by the CMS experiment a... 详细信息

The inclusive jet cross section is measured as a function of jet transverse momentum p_T and rapidity y. The measurement is performed using proton-proton collision data at s = 5.02 TeV, recorded by the CMS experiment at the LHC, corresponding to an integrated luminosity of 27.4 pb⁻¹. The jets are reconstructed with the anti-k_T algorithm using a distance parameter of R = 0.4, within the rapidity interval |y| < 2, and across the kinematic range 0.06 < p_T< 1 TeV. The jet cross section is unfolded from detector to particle level using the determined jet response and resolution. The results are compared to predictions of perturbative quantum chromodynamics, calculated at both next-to-leading order and next-to-next-to-leading order. The predictions are corrected for nonperturbative effects, and presented for a variety of parton distribution functions and choices of the renormalization/factorization scales and the strong coupling α_S. © The Author(s) 2025.

关键词： Hadron-Hadron Scattering Jet Physics QCD

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