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SSRN 2023年

作者： Wheeler, Kathryn I. Dietze, Michael C. LeBauer, David Peters, Jody Richardson, Andrew D. Thomas, R. Quinn Zhu, Kai Bhat, Uttam Munch, Stephan Buzbee, Raphaela Floreani Chenp, Min Goldstein, Benjamin Guo, Jessica S. Haoq, Dalei Jones, Chris Kelly-Fair, Mira Liup, Haoran Malmborg, Charlotte Neupane, Naresh Pal, Debasmita Ross, Arun A. Shirey, Vaughn Song, Yiluan Steen, McKalee Vance, Eric A. Woelmer, Whitney M. Wynne, Jacob Zachmann, Luke Department of Earth and Environment Boston University 685 Commonwealth Avenue BostonMA02215 United States Cooperative Programs for the Advancement of Earth System Science University Corporation for Atmospheric Research Foothills Laboratory Bldg 4 3300 Mitchell Lane BoulderCO80301 United States National Oceanic and Atmospheric Administration Foothills Laboratory Bldg 4 3300 Mitchell Lane BoulderCO80301 United States Department of Civil and Environmental Engineering Massachusetts Institute of Technology 15 Vassar St CambridgeMA02142 United States Arizona Experiment Station University of Arizona 1230 N Cherry Ave TucsonAZ85721 United States Department of Biological Sciences University of Notre Dame 100 Galvin Notre DameIN46556 United States School of Informatics Computing and Cyber Systems Northern Arizona University 1295 Knoles Dr. FlagstaffAZ86011 United States Center for Ecosystem Science and Society Northern Arizona University PO Box 5620 FlagstaffAZ86011 United States Department of Forest Resources and Environmental Conservation Virginia Polytechnic Institute State University 310 West Campus Drive BlacksburgVA24061 United States Department of Biological Sciences Virginia Polytechnic Institute State University 926 West Campus Drive BlacksburgVA24061 United States Institute for Global Change Biology University of Michigan 440 Church Street Ann ArborMI48109 United States School for Environment and Sustainability University of Michigan 440 Church Street Ann ArborMI48109 United States Institute of Marine Sciences University of California Santa Cruz 1156 High Street Santa CruzCA95060 United States Department of Applied Mathematics University of California Santa Cruz 1156 High Street Santa CruzCA95060 United States Department of Environmental Science Policy and Management University of California Berkeley 4004 Valley Life Sciences Building University of California Berkeley BerkeleyCA94720 United States Department of For

Accurate phenology models are important to predict how global climate change will continue to alter the timing of plant phenological events, such as spring greenup in deciduous broadleaf forests. While there is merit in long-term predictions, investigating how models can predict near-term (1– 35 days) canopy greenness throughout the spring allows us to validate performance and understanding now. The Ecological Forecasting Initiative’s NEON Forecasting Challenge, is an open challenge to the community to predict daily greenness values, measured through digital images collected by the PhenoCam Network at National Ecological Observatory Network (NEON) sites. For the first round of the challenge, which is presented here, teams were tasked to forecast phenology at eight deciduous broadleaf sites. A total of 192,536 predictions were submitted, representing eighteen models, including a persistence and a day of year mean null models. We found that forecast skill was highest when forecasting earlier in the greenup curve compared to the end, for shorter lead times, for sites that greened up earlier, and when submitting forecasts during times other than near budburst. The models based on day of year historical mean had the highest predictive skill across the challenge period. In this first round of the challenge, by synthesizing across forecasts, we started to elucidate what factors affect the predictive skill of near-term phenology forecasts, which future rounds will continue to investigate. © 2023, The Authors. All rights reserved.

关键词： Forecasting

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Ten quick tips for deep learning in biology

arXiv

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arXiv 2021年

作者： Lee, Benjamin D. Gitter, Anthony Greene, Casey S. Raschka, Sebastian Maguire, Finlay Titus, Alexander J. Kessler, Michael D. Lee, Alexandra J. Chevrette, Marc G. Stewart, Paul Allen Britto-Borges, Thiago Cofer, Evan M. Yu, Kun-Hsing Carmona, Juan Jose Fertig, Elana J. Kalinin, Alexandr A. Signal, Beth Lengerich, Benjamin J. Triche, Timothy J. Boca, Simina M. In-Q-Tel Labs School of Engineering and Applied Sciences Harvard University Department of Genetics Harvard Medical School United States Department of Biostatistics and Medical Informatics University of Wisconsin-Madison MadisonWI United States Morgridge Institute for Research MadisonWI United States Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Biochemistry and Molecular Genetics University of Colorado School of Medicine AuroraCO United States Center for Health AI University of Colorado School of Medicine AuroraCO United States Department of Statistics University of Wisconsin Madison United States Faculty of Computer Science Dalhousie University Canada University of New Hampshire Bioeconomy.XYZ United States Department of Oncology Johns Hopkins University United States Institute for Genome Sciences University of Maryland School of Medicine United States Genomics and Computational Biology Graduate Program University of Pennsylvania United States Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania United States Wisconsin Institute for Discovery Department of Plant Pathology University of Wisconsin-Madison United States Department of Biostatistics and Bioinformatics Moffitt Cancer Center TampaFL United States Section of Bioinformatics and Systems Cardiology Klaus Tschira Institute for Integrative Computational Cardiology University Hospital Heidelberg Germany University Hospital Heidelberg Germany Lewis-Sigler Institute for Integrative Genomics Princeton University PrincetonNJ United States Graduate Program in Quantitative and Computational Biology Princeton University PrincetonNJ United States Department of Biomedical Informatics Harvard Medical School United States Department of Pathology Brigham and Women's Hospital United States Philips Healthcare CambridgeMA United States Philips Research

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive modeling. Artificial neural networks are a particular class of machine learning algorithms and models that evolved into what is now described as deep learning. Given the computational advances made in the last decade, deep learning can now be applied to massive data sets and in innumerable contexts. Therefore, deep learning has become its own subfield of machine learning. In the context of biological research, it has been increasingly used to derive novel insights from high-dimensional biological data. To make the biological applications of deep learning more accessible to scientists who have some experience with machine learning, we solicited input from a community of researchers with varied biological and deep learning interests. These individuals collaboratively contributed to this manuscript's writing using the GitHub version control platform and the Manubot manuscript generation toolset. The goal was to articulate a practical, accessible, and concise set of guidelines and suggestions to follow when using deep learning. In the course of our discussions, several themes became clear: the importance of understanding and applying machine learning fundamentals as a baseline for utilizing deep learning, the necessity for extensive model comparisons with careful evaluation, and the need for critical thought in interpreting results generated by deep learning, among others. © 2021, CC BY.

关键词： Learning algorithms

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Generation of terahertz transients from Co2Fe0.4Mn0.6Si-Heusler-alloy/normal-metal nanobilayers excited by femtosecond optical pulses

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Physical Review Research 2021年第4期3卷 043025-043025页

作者： Sarah Heidtfeld Roman Adam Takahide Kubota Koki Takanashi Derang Cao Carolin Schmitz-Antoniak Daniel E. Bürgler Fangzhou Wang Christian Greb Genyu Chen Ivan Komissarov Hilde Hardtdegen Martin Mikulics Roman Sobolewski Shigemasa Suga Claus M. Schneider Research Centre Jülich Peter Grünberg Institute 52425 Jülich Germany Faculty of Physics University of Duisburg-Essen 47048 Duisburg Germany Institute for Materials Research Tohoku University Sendai 980-8577 Japan Center for Spintronics Research Network Tohoku University Sendai 980-8577 Japan Center for Science and Innovation in Spintronics (Core Research Cluster) Tohoku University Sendai 980-8577 Japan College of Physics National Demonstration Center for Experimental Applied Physics Education Qingdao University Qingdao 266071 China Materials Science Graduate Program University of Rochester Rochester New York 14627 USA Laboratory for Laser Energetics University of Rochester Rochester New York 14623 USA Department of Electrical and Computer Engineering University of Rochester Rochester New York 14627 USA Belarusian State University of Informatics and Radioelectronics Minsk 220013 Belarus Research Centre Jülich Ernst Ruska Centre for Microscopy and Spectroscopy with Electrons 52425 Jülich Germany Department of Physics and Astronomy University of Rochester Rochester New York 14627 USA The Institute of Scientific and Industrial Research Osaka University Ibaraki Osaka 567-0047 Japan Department of Physics University of California Davis Davis California 95616 USA

We generated pulses of electromagnetic radiation in the terahertz (THz) frequency range by optical excitation of Co2Fe0.4Mn0.6Si (CFMS)/normal-metal (NM) bilayer structures. The CFMS is a Heusler alloy showing a band gap in one spin channel and is therefore a half metal. We compared the THz emission efficiency in a systematic manner for four different CFMS/NM bilayers, where NM was either Pt, Ta, Cr, or Al. Our measurements show that the THz intensity is highest for a Pt capping. We also demonstrate the tunability of the THz amplitude by varying the magnetic field for all four bilayers. We attribute the THz generation to the inverse spin Hall effect. In order to investigate the role of the interface in THz generation, we measured the spin mixing conductance for each CFMS/NM bilayer using a ferromagnetic resonance method. We found that the spin-orbit coupling cannot completely describe the THz generation in the bilayers and that the spin transmission efficiency of the CFMS/NM interface and the spin diffusion length, as well as the oxidation of the NM layer, play crucial roles in the THz emission process.

关键词： Inverse spin Hall effect Magnetism Spin injection Spin pumping Spintronics Ferromagnetic resonance Terahertz time-domain spectroscopy

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AI-based Reconstruction for Fast MRI – A Systematic Review and Meta-analysis

arXiv

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arXiv 2021年

作者： Chen, Yutong Schönlieb, Carola-Bibiane Liò, Pietro Leiner, Tim Dragotti, Pier Luigi Wang, Ge Rueckert, Daniel Firmin, David Yang, Guang National Heart & Lung Institute Imperial College London LondonSW3 6NP United Kingdom Cardiovascular Research Centre Royal Brompton Hospital LondonSW3 6NP United Kingdom Faculty of Biology University of Cambridge CambridgeCB2 1RX United Kingdom Department of Applied Mathematics and Theoretical Physics University of Cambridge CambridgeCB3 0WA United Kingdom Department of Computer Science and Technology University of Cambridge CambridgeCB3 0FD United Kingdom Utrecht University Medical Centre Utrecht3584 CX Netherlands Department of Electrical and Electronic Engineering Imperial College London LondonSW7 2BU United Kingdom Biomedical Imaging Center Rensselaer Polytechnic Institute TroyNY12180 United States Department of Computing Imperial College London LondonSW7 2BU United Kingdom Institute for Medical Informatics Statistics and Epidemiology Technical University of Munich Munich81675 Germany

Compressed sensing (CS) has been playing a key role in accelerating the magnetic resonance imaging (MRI) acquisition process. With the resurgence of artificial intelligence, deep neural networks and CS algorithms are being integrated to redefine the state of the art of fast MRI. The past several years have witnessed substantial growth in the complexity, diversity, and performance of deep learning-based CS techniques that are dedicated to fast MRI. In this meta-analysis, we systematically review the deep learning-based CS techniques for fast MRI, describe key model designs, highlight breakthroughs, and discuss promising directions. We have also introduced a comprehensive analysis framework and a classification system to assess the pivotal role of deep learning in CS-based acceleration for MRI. © 2021, CC BY-NC-ND.

关键词： Compressed sensing

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Operational resource theory of nonclassicality via quantum metrology

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Physical Review Research 2020年第2期2卷 023400-023400页

作者： Wenchao Ge Kurt Jacobs Saeed Asiri Michael Foss-Feig M. Suhail Zubairy Institute for Quantum Science and Engineering (IQSE) and Department of Physics and Astronomy Texas A&M University College Station Texas 77843-4242 USA United States Army Research Laboratory Adelphi Maryland 20783 USA The Institute for Research in Electronics and Applied Physics (IREAP) College Park Maryland 20740 USA Department of Physics University of Massachusetts at Boston Boston Massachusetts 02125 USA Hearne Institute for Theoretical Physics Louisiana State University Baton Rouge Louisiana 70803 USA The National Center for Laser and Optoelectronics Technologies KACST Riyadh 11442 Saudi Arabia Center for Quantum Optics and Quantum Informatics (CQOQI) KACST Riyadh 11442 Saudi Arabia Joint Quantum Institute NIST/University of Maryland College Park Maryland 20742 USA Joint Center for Quantum Information and Computer Science NIST/University of Maryland College Park Maryland 20742 USA

The nonclassical properties of quantum states are of tremendous interest due to their potential applications in future technologies. It has recently been realized that the concept of a resource theory is a powerful approach to quantifying and understanding nonclassicality. To realize the potential of this approach, one must first find resource theoretic measures of nonclassicality that are operational, meaning that they also quantify the ability of quantum states to provide enhanced performance for specific tasks, such as precision sensing. Here we achieve a significant milestone in this endeavor by presenting such an operational resource theoretic measure. In addition to satisfying the requirements of a resource measure, it has the closest possible relationship to the quantum enhancement provided by a nonclassical state for measuring phase-space displacement: It is equal to this enhancement for pure states and has a tight upper bound on it for mixed states. We also show that a lower bound on this measure can be obtained experimentally using a simple Mach-Zehnder interferometer.

关键词： Quantum metrology Quantum optics Quantum states of light Quantum-to-classical transition Resource theories

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Use of the modern information technologies for continuous monitoring of transport infrastructure

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IOP Conference Series: Materials Science and engineering 2021年第1期1047卷

作者： A L Zolkin E A Domracheva A N Losev Yu M Avdeev Computer and Information Sciences Department Povolzhskiy State University of Telecommunications and Informatics L.Tolstogo Street 23 Samara 443010 Russia Telecommunication systems and networks department State University of Telecommunications Solomenskaya Street 7 Kiev 03110 Ukraine Department of Applied Informatics Federal State Budgetary Educational Institution of Higher Education 'Russian Timiryazev State Agrarian University' Timiryazevskaya Street 49 Moscow 127550 Russia Department of Urban Cadastre and Geodesy of the Engineering and Construction Institute Vologda State University Lenin Street 15 Vologda 160000 Russia

The concepts of universality and general applicability of information networks as well as the issues of using networks in specific directions are considered in the article on the example of the convergence of transport infrastructure and information networks. An analysis of modern information networks has been carried out and the following three main directions have been identified: infrastructure as a service, platform as a service, software as a service. The article examines the issues of automation of the customer relationship management by introducing a CRM system in order to improve transport support and logistics services provided by companies at the competitive market of logistics services. The basic principles of convergence of information networks and transport infrastructure are presented on the example of a transport and logistics system. The issues of use of the modern information technologies for continuous monitoring of transport infrastructure are considered.

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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990-2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021

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LANCET INFECTIOUS DISEASES 2025年第5期25卷 519-536页

作者： Kyu, Hmwe Hmwe Vongpradith, Avina Dominguez, Regina-Mae Villanueva Ma, Jianing Albertson, Samuel B. Novotney, Amanda Khalil, Ibrahim A. Troeger, Christopher E. Doxey, Matthew C. Ledesma, Jorge R. Sirota, Sarah Brooke Bender, Rose Grace Swetschinski, Lucien R. Cunningham, Matthew Spearman, Sandra Abate, Yohannes Habtegiorgis Abd Al Magied, Abdallah H. A. Abd ElHafeez, Samar Abdoun, Meriem Abera, Bayeh Abidi, Hassan Aboagye, Richard Gyan Abtew, Yonas Derso Abualruz, Hasan Abu-Gharbieh, Eman Abukhadijah, Hana J. Aburuz, Salahdein Addo, Isaac Yeboah Adekanmbi, Victor Adetunji, Charles Oluwaseun Oluwaseun Adeyeoluwa, Temitayo Esther Adhikary, Ripon Kumar Adnani, Qorinah Estiningtyas Sakilah Adra, Saryia Adzigbli, Leticia Akua Afolabi, Aanuoluwapo Adeyimika Afzal, Muhammad Sohail Afzal, Saira Agampodi, Suneth Buddhika Agide, Feleke Doyore Ahinkorah, Bright Opoku Ahmad, Aqeel Ahmad, Sajjad Ahmed, Ali Ahmed, Ayman Ahmed, Haroon Ahmed, Saeed Akinosoglou, Karolina Akter, Ema Al Awaidy, Salah Alajlani, Muaaz M. Alam, Khurshid Albakri, Almaza Albashtawy, Mohammed Aldhaleei, Wafa A. Algammal, Abdelazeem M. Al-Gheethi, Adel Ali Saeed Ali, Abid Syed Shujait Ali Ali, Waad Alif, Sheikh Mohammad Aljunid, Syed Mohamed Al-Marwani, Sabah Almazan, Joseph Uy Al-Mekhlafi, Hesham M. Almustanyir, Sami Alqahatni, Saleh A. Alrawashdeh, Ahmad Al-Rifai, Rami H. Alsabri, Mohammed A. Altaf, Awais Altirkawi, Khalid A. Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Alyahya, Mohammad Sharif Ibrahim Al-Zyoud, Walid A. Amugsi, Dickson A. Andrei, Catalina Liliana Antoni, Sebastien Anuoluwa, Boluwatife Stephen Anuoluwa, Iyadunni Adesola Anwari, Saleha Anwar Palwasha Apostol, Geminn Louis Carace Arabloo, Jalal Arafat, Mosab Aravkin, Aleksandr Y. Areda, Demelash Aregawi, Brhane Berhe Aremu, Abdulfatai Arndt, Michael Benjamin Asgedom, Akeza Awealom Ashraf, Tahira Athari, Seyyed Shamsadin Atreya, Alok Ayele, Firayad Azadi, Davood Azhar, Gulrez Shah Aziz, Shahkaar Azzam, Ahmed Y. Babu, Giridhara Rathnaiah Taghanaki, Pegah Bahrami Bahramian, Saeed Balakrishna Department of Health Metrics Sciences School of Medicine Institute for Health Metrics and Evaluation University of Washington Seattle 98195 WA United States Institute for Health Metrics and Evaluation University of Washington Seattle WA United States Department of Health Metrics Sciences School of Medicine University of Washington Seattle WA United States Center for Biostatistics Ohio State University Columbus OH United States Department of Global Health University of Washington Seattle WA United States Urban Indian Health Institute Seattle Indian Health Board Seattle WA United States School of Medicine Yale University New Haven CT United States Department of Clinical Governance and Quality Improvement Aleta Wondo General Hospital Aleta Wondo Ethiopia College of Pharmacy Ajman University Ajman United Arab Emirates Department of Epidemiology Alexandria University Alexandria Egypt Department of Medicine University of Sétif Algeria Sétif Algeria Department of Health Sétif Algeria Department of Medical Microbiology Bahir Dar University Bahir Dar Ethiopia Department of Biology Ghent University Ghent Belgium Laboratory Technology Sciences Department Yasuj University of Medical Sciences Yasuj Iran Department of Family and Community Health University of Health and Allied Sciences Ho Ghana Department of Biomedical Science Arba Minch University Arba Minch Ethiopia Department of Nursing Al Zaytoonah University of Jordan Amman Jordan Amman Jordan Department of Clinical Sciences Sharjah United Arab Emirates Department of Biopharmaceutics and Clinical Pharmacy University of Jordan Amman Jordan Medical Research Center-Academic Health System Hamad Medical Corporation Doha Qatar College of Pharmacy University of Jordan Amman Jordan Department of Therapeutics United Arab Emirates University Al Ain United Arab Emirates School of Medicine University of Sydney Sydney NSW Australia Centre for Social Research in Health University of New South Wales Syd

Background Diarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age groups of children younger than 5 years are scarce, and the burden in children older than 5 years and in adults is also understudied. We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to assess the burden of, and trends in, diarrhoeal diseases overall and attributable to 13 pathogens, as well as the contributions of associated risk factors, in children and adults in 204 countries and territories from 1990 to 2021. Methods We used the Cause of Death Ensemble modelling strategy to analyse vital registration data, verbal autopsy data, mortality surveillance data, and minimally invasive tissue sampling data. We used DisMod-MR (version 2.1), a Bayesian meta-regression tool, to analyse incidence and prevalence data identified via systematic reviews, population-based surveys, and claims and inpatient data. We calculated diarrhoeal disability-adjusted life-years (DALYs) as the sum of years of life lost (YLLs) and years lived with disability (YLDs) for each location, year, and age-sex group. For aetiology estimation, we used a counterfactual approach to quantify population-attributable fractions (PAFs). Additionally, we estimated the diarrhoeal disease burden attributable to the independent effects of risk factors using the comparative risk assessment framework. Findings In 2021, diarrhoeal diseases caused an estimated 1.17 million (95% uncertainty interval 0.793-1.62) deaths globally, representing a 60.3% (50.6-69.0) decrease since 1990 (2.93 million [2.31-3.73] deaths). The most pronounced decline was in children younger than 5 years, with a 79.2% (72.4-84.6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147-221) in 1990 to 51.4 million (39.9-65.9) in 2021. In 2021, an esti

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Roadmap on spatiotemporal light fields

arXiv

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arXiv 2022年

作者： Shen, Yijie Zhan, Qiwen Wright, Logan G. Christodoulides, Demetrios N. Wise, Frank W. Willner, Alan E. Zhao, Zhe Zou, Kai-Heng Liao, Chen-Ting Hernández-García, Carlos Murnane, Margaret Porras, Miguel A. Chong, Andy Wan, Chenhao Bliokh, Konstantin Y. Yessenov, Murat Abouraddy, Ayman F. Wong, Liang Jie Go, Michael Kumar, Suraj Guo, Cheng Fan, Shanhui Papasimakis, Nikitas Zheludev, Nikolay I. Chen, Lu Zhu, Wenqi Agrawal, Amit Jolly, Spencer W. Dorrer, Christophe Alonso, Benjamín Lopez-Quintas, Ignacio López-Ripa, Miguel Sola, Íñigo J. Fang, Yiqi Gong, Qihuang Liu, Yunquan Huang, Junyi Zhang, Hongliang Ruan, Zhichao Mounaix, Mickael Fontaine, Nicolas K. Carpenter, Joel Dorrah, Ahmed H. Capasso, Federico Forbes, Andrew Optoelectronics Research Centre Centre for Photonic Metamaterials University of Southampton SouthamptonSO17 1BJ United Kingdom School of Optical-Electrical and Computer Engineering University of Shanghai for Science and Technology Shanghai200093 China Zhangjiang Laboratory 100 Haike Road Shanghai201204 China Physics & Informatics Laboratories NTT Research Inc. 940 Stewart Drive SunnyvaleCA94085 United States School of Applied and Engineering Physics Cornell University IthacaNY14853 United States College of Optics & Photonics-CREOL University of Central Florida OrlandoFL32816 United States Department of Electrical Engineering University of Southern California Los AngelesCA90089 United States JILA Department of Physics University of Colorado and NIST BoulderCO80309 United States Grupo de Investigación en Aplicaciones del Láser y Fotónica Departamento de Física Aplicada Universidad de Salamanca Salamanca37008 Spain Grupo de Sistemas Complejos ETSIME Universidad Politécnica de Madrid Rios Rosas 21 Madrid28003 Spain Physics Department Pusan National Umiversity Geumjeong-gu Busan46241 Korea Republic of School of Optical and Electronic Information Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Hubei Wuhan430074 China Theoretical Quantum Physics Laboratory RIKEN Cluster for Pioneering Research Saitama Wako-shi351-0198 Japan School of Electrical and Electronic Engineering Nanyang Technological University 50 Nanyang Avenue Singapore639798 Singapore Department of Applied Physics Stanford University StanfordCA94305 United States Ginzton Laboratory Department of Electrical Engineering Stanford University StanfordCA94305 United States Centre for Disruptive Photonic Technologies School of Physical and Mathematical Sciences The Photonics Institute Nanyang Technological University Singapore637378 Singapore National Institute of Standards and Technology GaithersburgMD20899 United States Maryla

Spatiotemporal sculpturing of light pulse with ultimately sophisticated structures represents the holy grail of the human everlasting pursue of ultra-fast information transmission and processing as well as ultra-intense energy concentration and extraction. It also holds the key to unlock new extraordinary fundamental physical effects. Traditionally, spatiotemporal light pulses are always treated as spatiotemporally separable wave packet as solution of the Maxwell's equations. In the past decade, however, more generalized forms of spatiotemporally nonseparable solution started to emerge with growing importance for their striking physical effects. This roadmap intends to highlight the recent advances in the creation and control of increasingly complex spatiotemporally sculptured pulses, from spatiotemporally separable to complex nonseparable states, with diverse geometric and topological structures, presenting a bird's eye viewpoint on the zoology of spatiotemporal light fields and the outlook of future trends and open challenges. © 2022, CC0.

关键词： Maxwell equations

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Measurements of inclusive and differential cross sections for the Higgs boson production and decay to four-leptons in proton-proton collisions at s = 13 TeV

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Journal of High Energy Physics 2023年第8期2023卷 40页

作者： Hayrapetyan, A. Tumasyan, A. Adam, W. Andrejkovic, J.W. Bergauer, T. Chatterjee, S. Damanakis, K. Dragicevic, M. Escalante Del Valle, A. Hussain, P.S. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I. Schieck, J. Schöfbeck, R. Schwarz, D. Sonawane, M. Templ, S. Waltenberger, W. Wulz, C.-E. Darwish, M.R. Janssen, T. Kello, T. Van Mechelen, P. Bols, E.S. D’Hondt, J. De Moor, A. Delcourt, M. El Faham, H. Lowette, S. Makarenko, I. Morton, A. Müller, D. Sahasransu, A.R. Tavernier, S. Van Putte, S. Vannerom, D. Clerbaux, B. Dansana, S. De Lentdecker, G. Favart, L. Hohov, D. Jaramillo, J. Lee, K. Mahdavikhorrami, M. Malara, A. Paredes, S. Pétré, L. Postiau, N. Thomas, L. Vanden Bemden, M. Vander Velde, C. Vanlaer, P. De Coen, M. Dobur, D. Knolle, J. Lambrecht, L. Mestdach, G. Rendón, C. Samalan, A. Skovpen, K. Tytgat, M. Van Den Bossche, N. Vermassen, B. Wezenbeek, L. Benecke, A. Bruno, G. Bury, F. Caputo, C. Delaere, C. Donertas, I.S. Giammanco, A. Jaffel, K. Jain, Sa. Lemaitre, V. Lidrych, J. Mastrapasqua, P. Mondal, K. Tran, T.T. Wertz, S. Alves, G.A. Coelho, E. Hensel, C. Moraes, A. Rebello Teles, P. Aldá Júnior, W.L. Alves Gallo Pereira, M. Barroso Ferreira Filho, M. Brandao Malbouisson, H. Carvalho, W. Chinellato, J. Da Costa, E.M. Da Silveira, G.G. De Jesus Damiao, D. Dos Santos Sousa, V. Fonseca De Souza, S. Martins, J. Mora Herrera, C. Mota Amarilo, K. Mundim, L. Nogima, H. Santoro, A. Silva Do Amaral, S.M. Sznajder, A. Thiel, M. Vilela Pereira, A. Bernardes, C.A. Calligaris, L. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Orzari, B. Padula, Sandra S. Aleksandrov, A. Antchev, G. Hadjiiska, R. Iaydjiev, P. Misheva, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Shumka, E. Keshri, S. Thakur, S. Cheng, T. Guo, Q. Javaid, T. Mittal, M. Yuan, L. Bauer, G. Hu, Z. Yi, K. Chen, G.M. Chen, H.S. Chen, M. Iemmi, F. Jiang, C.H. Kapoor, A. Liao, H. Liu, Z.-A. Monti, F. Sharma, R. Song, J.N. Tao, J. Wang, J. Zhang, C. Zhang, H. Agapitos, A. Ba Yerevan Physics Institute Yerevan Armenia Institut für Hochenergiephysik Vienna Austria Universiteit Antwerpen Antwerpen Belgium Vrije Universiteit Brussel Brussel Belgium Université Libre de Bruxelles Bruxelles Belgium Ghent University Ghent Belgium Université Catholique de Louvain Louvain-la-Neuve Belgium Centro Brasileiro de Pesquisas Fisicas Rio de Janeiro Brazil Universidade do Estado do Rio de Janeiro Rio de Janeiro Brazil Universidade Estadual Paulista Universidade Federal do ABC São Paulo Brazil Institute for Nuclear Research and Nuclear Energy Bulgarian Academy of Sciences Sofia Bulgaria University of Sofia Sofia Bulgaria Instituto De Alta Investigación Universidad de Tarapacá Casilla 7 D Arica Chile Beihang University Beijing China Department of Physics Tsinghua University Beijing China Institute of High Energy Physics Beijing China State Key Laboratory of Nuclear Physics and Technology Peking University Beijing China Sun Yat-Sen University Guangzhou China University of Science and Technology of China Hefei China Institute of Modern Physics and Key Laboratory of Nuclear Physics and Ion-beam Application (MOE) — Fudan University Shanghai China Zhejiang University Zhejiang Hangzhou China Universidad de Los Andes Bogota Colombia Universidad de Antioquia Medellin Colombia University of Split Faculty of Electrical Engineering Mechanical Engineering and Naval Architecture Split Croatia University of Split Faculty of Science Split Croatia Institute Rudjer Boskovic Zagreb Croatia University of Cyprus Nicosia Cyprus Charles University Prague Czech Republic Escuela Politecnica Nacional Quito Ecuador Universidad San Francisco de Quito Quito Ecuador Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics Cairo Egypt Center for High Energy Physics (CHEP-FU) Fayoum University El-Fayoum Egypt National Institute of Chemical Physics and Biophysics Tallinn Estonia Department of Physics

Measurements of the inclusive and differential fiducial cross sections for the Higgs boson production in the H → ZZ → 4ℓ (ℓ = e, μ) decay channel are presented. The results are obtained from the analysis of proton-proton collision data recorded by the CMS experiment at the CERN LHC at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 138 fb⁻¹. The measured inclusive fiducial cross section is 2.73 ± 0.26 fb, in agreement with the standard model expectation of 2.86 ± 0.1 fb. Differential cross sections are measured as a function of several kinematic observables sensitive to the Higgs boson production and decay to four leptons. A set of double-differential measurements is also performed, yielding a comprehensive characterization of the four leptons final state. Constraints on the Higgs boson trilinear coupling and on the bottom and charm quark coupling modifiers are derived from its transverse momentum distribution. All results are consistent with theoretical predictions from the standard model. © The Author(s) 2023.

关键词： Hadron-Hadron Scattering Higgs Physics

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Metadata Concepts for Advancing the Use of Digital Health Technologies in Clinical Research

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Digital Biomarkers 2019年第3期3卷 116-132页

作者： Badawy, Reham Hameed, Farhan Bataille, Lauren Little, Max A. Claes, Kasper Saria, Suchi Cedarbaum, Jesse M. Stephenson, Diane Neville, Jon Maetzler, Walter Espay, Alberto J. Bloem, Bastiaan R. Simuni, Tanya Karlin, Daniel R. School of Computer Science University of Birmingham Birmingham United Kingdom Digital Medicine and Pfizer Innovation Research Lab Early Clinical Development Pfizer Inc. CambridgeMA United States College of Computer and Information Science Northeastern University BostonMA United States Analytics Informatics and Business Intelligence Chief Digital Office Pfizer Inc. New YorkNY United States Michael J. Fox Foundation for Parkinson's Research New YorkNY United States Media Lab Massachusetts Institute of Technology CambridgeMA United States UCB Biopharma Brussels Belgium Machine Learning and Healthcare Laboratory Departments of Computer Science Statistics and Health Policy Malone Center for Engineering in Healthcare Armstrong Institute for Patient Safety and Quality Johns Hopkins University BaltimoreMD United States Biogen CambridgeMA United States Critical Path Institute TucsonAZ United States Clinical Data Interchange Standards Consortium AustinTX United States Department of Neurology Christian Albrecht University Kiel Germany James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders University of Cincinnati CincinnatiOH United States Department of Neurology Donders Institute for Brain Cognition and Behavior Radboud University Medical Center Nijmegen Netherlands Department of Neurology Gardner Center for Parkinson's Disease and Movement Disorders UC Gardner Neuroscience Institute University of Cincinnati CincinnatiOH United States Tufts University School of Medicine BostonMA United States HealthMode New YorkNY United States School of Engineering and Applied Science Aston University BirminghamB47ET United Kingdom

Digital health technologies (smartphones, smartwatches, and other body-worn sensors) can act as novel tools to aid in the diagnosis and remote objective monitoring of an individual's disease symptoms, both in clinical care and in research. Nonetheless, such digital health technologies have yet to widely demonstrate value in clinical research due to insufficient data interpretability and lack of regulatory acceptance. Metadata, i.e., data that accompany and describe the primary data, can be utilized to better understand the context of the sensor data and can assist in data management, data sharing, and subsequent data analysis. The need for data and metadata standards for digital health technologies has been raised in academic and industry research communities and has also been noted by regulatory authorities. Therefore, to address this unmet need, we here propose a metadata set that reflects regulatory guidelines and that can serve as a conceptual map to (1) inform researchers on the metadata they should collect in digital health studies, aiming to increase the interpretability and exchangeability of their data, and (2) direct standard development organizations on how to extend their existing standards to incorporate digital health technologies. The proposed metadata set is informed by existing standards pertaining to clinical trials and medical devices, in addition to existing schemas that have supported digital health technology studies. We illustrate this specifically in the context of Parkinson's disease, as a model for a wide range of other chronic conditions for which remote monitoring would be useful in both care and science. We invite the scientific and clinical research communities to apply the proposed metadata set to ongoing and planned research. Where the proposed metadata fall short, we ask users to contribute to its ongoing revision so that an adequate degree of consensus can be maintained in a rapidly evolving technology landscape. © 2019 The Author(s

关键词： Metadata

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