In this paper, we propose an efficient mining approach which adopts an indexing mechanism to speed up the execution efficiency and reduce the memory requirement in the utility mining process. Besides, a pruning strate...
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In this paper, we propose an efficient mining approach which adopts an indexing mechanism to speed up the execution efficiency and reduce the memory requirement in the utility mining process. Besides, a pruning strategy is designed to reduce the number of unpromising itemsets for mining. The experimental results also show the performance of the proposed approach is better than that of traditional two-phase utility mining algorithm under different parameters.
The worldwide prevalence of epilepsy is approximately 1%, and 25% of epilepsy patients cannot be treated sufficiently by available therapies. Brain stimulation with closed-loop seizure control has recently been propos...
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The worldwide prevalence of epilepsy is approximately 1%, and 25% of epilepsy patients cannot be treated sufficiently by available therapies. Brain stimulation with closed-loop seizure control has recently been proposed as an innovative and effective alternative. In this paper, a portable closed-loop brain computer interface for seizure control was developed and shown with several aspects of advantages, including high seizure detection rate (92-99% during wake-sleep states), low false detection rate (1.2-2.5%), and small size. The seizure detection and electrical stimulation latency was not greater than 0.6 s after seizure onset. A wireless communication feature also provided flexibility for subjects freeing from the hassle of wires. Experimental data from freely moving rats supported the functional possibility of a real-time closed-loop seizure controller.
This paper handles the problem of finding high on-shelf utility itemsets, which considers not only individual profit and quantity of each item in a transaction but also on-shelf periods of the items. We have extended ...
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A numerical method is proposed to simulate the corresponding terahertz photoresponse which is induced by radiations between source-and-gate and gate-and-drain electrodes in field effect transistors. Simulations illust...
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Rule-based reasoning (RBR) and case-based reasoning (CBR) are two complementary alternatives for building knowledge-based “intelligent” decision-support systems. RBR and CBR can be combined in three main ways: RBR f...
Rule-based reasoning (RBR) and case-based reasoning (CBR) are two complementary alternatives for building knowledge-based “intelligent” decision-support systems. RBR and CBR can be combined in three main ways: RBR first, CBR first, or some interleaving of the two. The N EST system, described in this paper, allows us to invoke both components separately and in arbitrary order. In addition to the traditional network of propositions and compositional rules, N EST also supports binary, nominal, and numeric attributes used for derivation of proposition weights, logical (no uncertainty) and default (no antecedent) rules, context expressions, integrity constraints, and cases. The inference mechanism allows use of both rule-based and case-based reasoning. Uncertainty processing (based on Hájek′s algebraic theory) allows interval weights to be interpreted as a union of hypothetical cases, and a novel set of combination functions inspired by neural networks has been added. The system is implemented in two versions: stand-alone and web-based client server. A user-friendly editor covering all mentioned features is included.
Diabetes mellitus is a general metabolic disease commonly leading patients to skeletal disorders such as osteoporosis and bone fracture. Previous studies had shown that appropriate stimulation with low intensity pulse...
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ISBN:
(纸本)9781457703829
Diabetes mellitus is a general metabolic disease commonly leading patients to skeletal disorders such as osteoporosis and bone fracture. Previous studies had shown that appropriate stimulation with low intensity pulsed ultrasound (LIPUS) may accelerate the proliferation and differentiation of osteoblasts for promoting fracture healing. In vitro experiments were carried out on the mouse osteoblastic cells which were cultured in the medium with either a normal glucose concentration of 5mM or high glucose concentration of 33mM. A 1 MHz LIPUS of a 100 mW/cm2 SATA intensity arranged from 20% duty cycle of a 1 kHz pulse repetition frequency was applied to daily stimulate osteoblasts for ten minutes. The responses of obsteoblasts with insonification were assessed by cell proliferation and gene expression from measurements of reverse transcriptase-ploymerase chain reaction (RT-PCR), osteoprotegerin (OPG), alkaline phosphatase (ALP), and osteocalcin (OCN) mRNA expression. Experiments were grouped into A: cells cultured in normal medium; B: cells cultured in normal medium and insonified with LIPUS; C: cells cultured in high glucose medium; D: cells cultured in high glucose medium and insonified with LIPUS. Results obtained from groups B, C, and D all showed that the corresponding growth of osteoblasts tended to increase compared to that of cells from the control group A. Specifically, the highest proliferation was found associated with osteoblasts of group D. The RT-PCR results revealed that mRNA levels of OPG corresponding to experimental groups of B, C, and D were respectively to be 1.29, 1.38, 1.62-fold more than that of control group; mRNA levels of ALP were respectively to be 1.18, 1.17, 1.38-fold more than that of control group and mRNA levels of OCN were respectively to be 1.41, 0.73, 1.22-fold more than that of control group. OCN mRNA expression was increased for those osteoblasts insonified with LIPUS from groups B and D, and that tended to be decreased for cells cul
Transcriptomic technologies (DNA microarrays, Next generation sequencers) represent a major innovation in biomedical research contributing an unprecedented wealth of data regarding genome-wide inspection of an organis...
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The Internet has been a huge resource for sharing and collecting information including health related information. Some health related information is written by patients (lay persons) discussing their experience about...
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The Internet has been a huge resource for sharing and collecting information including health related information. Some health related information is written by patients (lay persons) discussing their experience about health problems and treatments. This paper introduces our initial work on providing physicians with clinically useful patient health writings. More specifically, the paper presented our experiments, as a part of the whole research work, on filtering health related text from patient health writings. We focused on selecting possible feature for classifying text from breast cancer mailing list into health and non health related text. Using KNN classification method, we experimented with various features, i.e. all terms, all terms except most frequently used terms, UMLS terms, health related UMLS terms, and health related UMLS semantic types. The experiments showed that UMLS terms extracted from the text is a good feature, compared to the other features.
Reducing the power consumption while maintaining the response time constraint has been an important goal in server system design. One of the techniques widely explored in the literature to achieve this goal is Dynamic...
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ISBN:
(纸本)9781424475469
Reducing the power consumption while maintaining the response time constraint has been an important goal in server system design. One of the techniques widely explored in the literature to achieve this goal is Dynamic Voltage Scaling (DVS). However, DVS is not efficient in modern systems where the overall power consumption includes a large portion of static power consumption. In this paper, we aim to reduce the static power consumption by Dynamic Power Management (DPM) with sleep model in addition to DVS. We propose a smart PowerSleep power-saving scheme, where a procrastination technique is adopted to carefully aggregate jobs to reduce the overhead of transitions in and out of the sleep mode. We also observe that PowerSleep might not always be a good choice due to the mode transition overhead when the server utilization is high, where instead we use PowerIdle power-saving scheme with DVS only. By modeling the system with M/G/1/PS queuing model and further extensions, we present how to minimize the mean power consumption of the server under the given mean response time constraint for both power-saving schemes. Simulation results show that our smart PowerSleep scheme significantly outperforms the simple power saving scheme which adopts sleep mode.
Histological examination remains the most direct means to assess the inflammatory tissue. It however is still with the nature of invasiveness and is time consuming for the preparation of tissue slices. The slice appar...
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ISBN:
(纸本)9781457703829
Histological examination remains the most direct means to assess the inflammatory tissue. It however is still with the nature of invasiveness and is time consuming for the preparation of tissue slices. The slice apparently is not applicable for a long term observation of the tissue in situ. For these reasons, this study is to explore another approach to assess the inflammatory skin using strengths and statistical parameters of high frequency ultrasonic backscattering signals. The experiments were performed from the dorsal skins of BALB/c mice using a 50 MHz ultrasound. The dorsal skins of different mice were injected with a 0.15 ml of either saline or lipopolysaccharides (LPS) with dosage of 2 mg/ml to be as the control group or to induce the local inflammation of the skin as the experiment group, respectively. Each set of experiments was arranged for four days, in which images and backscattered signals of the skins from both control and experiment groups were scanned and acquired daily. Parameters to assess the inflammation included a typical cutaneous thickness estimated from ultrasonic image and that those of integrated backscatter (IB) and Nakagami parameter (m) were calculated from regions of acquired backscattering signals. Results showed that there were no significant differences among measurements of those control groups injected with saline. On the other hand, the inflammatory skin induced by LPS injection tended to result an increase of cutaneous thickness from 0.38+-0.07 mm of normal skin to 0.7+-0.11 mm of the fourth day. The corresponding IB tended to decrease from -182.5+-2.7 dB to -194.4+-2.5 dB and m increase slightly from 0.36+-0.08 to 0.51+-0.12. Those thickness and quantitative parameters variations could be directly associated with changes of tissue properties due to a transfer of massive fluid shifts from the intravascular space into the interstitium and intracellular spaces in the inflammatory skin. This study has demonstrated that cutaneous th
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