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2007 IEEE Nuclear science Symposium Conference, vol.10

作者： Tsutomu Zeniya Hiroshi Watabe Antti Sohlberg Toru Inomata Hiroyuki Kudo Hidehiro Iida Department of Investigative Radiology Advanced Medical Engineering Center National Cardiovascular Center Research Institute Suita Osaka Japan Department of Clinical Physiology and Nuclear Medicine Kuopio University Hospital Kuopio Finland National Cardiovascular Center Research Institute Osaka Japan Department of Computer Science Graduate School of Systems and Information Engineering University of Tsukuba Tsukuba Japan

Pinhole SPECT can provide high-resolution image with high sensitivity when a collimator is close to an object. However, truncation causes artifact and decreases quantitative accuracy. Defrise et al proposed new reconstruction theory to prevent overestimation due to truncation. In this paper, we applied Defrise theory to three-dimensional pinhole SPECT reconstruction and validated our implementation by computer simulation.

关键词： Image reconstruction Collimators Imaging phantoms Radioactive materials Cameras Spatial resolution computer simulation Geometry Scattering Pixel

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Using a Grid Platform for Enabling Real Time User Modeling in On-line Campus

Using a Grid Platform for Enabling Real Time User Modeling i...

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International Conference on Complex, Intelligent and Software Intensive Systems, CISIS

作者： Santi Caballe Fatos Xhafa Thanasis Daradoumis Joan Esteve Leonard Barolli Arjan Durresi Universitat Oberta de Catalunya Barcelona Catalunya ES Dept. of Languages and Informatics Systems Polytechnic University of Catalonia Barcelona Spain Department of Computer Science Multimedia and Telecommunication Open University of Catalonia Barcelona Spain Department of Information and Communication Engineering Fukuoka Institute of Technology (FIT) Higashi-ku Fukuoka Japan Department of Computer Science Louisiana State University Baton Rouge LA USA

User modelling in on-line distance learning is an important research field focusing on two important aspects: describing and predicting students' actions and intentions as well as adapting the learning process to students' features, habits, preferences, and so on. The aim is to greatly stimulate and improve the learning experience. Indeed, on the one hand, students' intentions may change during the realization of learning activities and thus their actions evolve accordingly as the learning process moves forward. On the other hand, adaptive systems can effectively plan and design appropriate learning tasks according to students' features, habits and interests with the aim of facilitating the achievement of the learning goal. In this context, user modelling implies a continuous processing and analysis of user interaction data during long-term learning activities, which produces large and considerably complex information. As a consequence, processing this information is costly and could require computational capacity beyond that of a single computer. In this paper, we show how a grid approach can considerably decrease the processing time of log data of on-line distance educational Web-based systems. Our prototype is based on the master-worker paradigm and is implemented using a peer-to-peer platform running on the Planetlab nodes. The results of our study show the feasibility of using grid middleware to speed and scale up the processing of log data and thus achieve an efficient and dynamic user modeling in on-line distance learning

关键词： computer aided instruction Adaptive systems computer science Predictive models Context modeling information analysis Peer to peer computing Software systems Application software Usability

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A Conceptual Persistent Healthcare Quality Improvement Process for Software Development Management

A Conceptual Persistent Healthcare Quality Improvement Proce...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Jen-Chiun Lin Mei-Ju Su Po-Hsun Cheng Yung-Chien. Weng Sao-Jie Chen Jin-Shin Lai Feipei Lai Department of Electrical Engineering National Taiwan University Taipei Taiwan Graduate Institute of Electronic Engineering and Department of Electrical Engineering National Taiwan University Taipei Taiwan National Taiwan University Hospital National Taiwan University College of Medicine Taipei Taiwan Department of Computer Science and Information Engineering National Taiwan University Taipei Taiwan Department of Physical Medicine and Rehabilitation and Department of Medical Informatics National Taiwan University Hospital National Taiwan University College of Medicine Taiwan

This paper illustrates a sustained conceptual service quality improvement process for the management of software development within a healthcare enterprise. Our proposed process is revised from Niland's healthcare quality information system (HQIS). This process includes functions to survey the satisfaction of system functions, describe the operation bylaws on-line, and provide on-demand training. To achieve these goals, we integrate five information systems in National Taiwan University Hospital, including healthcare information systems, health quality information system, requirement management system, executive information system, and digital learning system, to form a full Deming cycle. A preliminary user satisfaction survey showed that our outpatient information system scored an average of 71.31 in 2006.

关键词： medical services Software development management Management information systems Quality management Programming Bylaws Management training Hospitals information management Learning systems

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An information Theoretic Framework for Ontology-based Bioinformatics

An Information Theoretic Framework for Ontology-based Bioinf...

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information Theory and Applications Workshop, ITA

作者： Gil Alterovitz Michael Xiang Marco F. Ramoni Harvard Partners Center for Genetics and Genomics Harvard Medical School Boston MA USA Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge MA USA Department of Biology Massachusetts Institute of Technology Cambridge MA USA Division of Health Sciences and Technology Harvard Medical School and Massachusetts Institute of Technology Boston MA Children's Hospital Informatics Program Boston MA Harvard Partners Center for Genetics and Genomics Harvard Medical School Boston MA.

With myriad information being generated from high-throughput experiments such as microarrays and sequencing technologies, an ever-increasing amount of data is being recorded and analyzed with the help of hierarchical ontologies, such as the gene ontology (GO). We have developed a novel framework- based on the well established foundations of information theory- that allows for the evaluation of new types of hypotheses. The framework, encapsulated in open biomedical ontology-based exploration and search (OBOES), has already been applied in the investigation of different kinds of questions. The resulting framework enables the new field of information theoretic ontology-based analysis. We have applied this framework to create methods to re-engineer ontologies, explore fundamental questions on the evolution of biological complexity, determine optimal ontology terms for bioinformatics analysis, and quantify the usefulness of biofluids as proxies for tissues/diseases. In each case, we found that our methods provide novel, significant findings. An open source Java implementation of OBOES is available at: http://***.

关键词： Ontologies Bioinformatics Genomics information analysis Biological information theory information theory Genetic communication Humans Biochemistry Frequency

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Improved Dynamic Time Warping Based on the Discrete Wavelet Transform

Improved Dynamic Time Warping Based on the Discrete Wavelet ...

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IEEE International Symposium on Multimedia Workshops (ISMW)

作者： Sylvio Barbon Junior Rodrigo Capobianco Guido Shi-Huang Chen Lucimar Sasso Vieira Fabricio Lopes Sanchez Department of Physics and Informatics Institute of Physics São Carlos Brazil Department of Bio Engineering University of São Paulo Sao Paulo Brazil University of São Paulo Avenida Trabalhador São Carlense Sao Carlos Brazil State of São Paulo Brazil Department of Computer Science and Information Engineering Shu Te University Kaohsiung Taiwan

ISBN: (纸本)9780769530840;0769530842

Dynamic Time Warping (DTW) is a pattern matching approach that can be used for limited vocabulary speech recognition, which is based on a temporal alignment of the input signal with the template models. The main drawback of this method is its high computational cost when the length of the signals increases. This paper presents a modified ver- sion of the DTW, based on the Discrete Wavelet Transform (DWT), that reduces its original complexity. Many wavelet families with different support-sizes are experimented and the corresponding results are reported.

关键词： Discrete wavelet transforms Automatic speech recognition Pattern matching Speech recognition Hidden Markov models Physics Computational efficiency Conferences informatics computer science

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Developing a computer science-specific learning taxonomy 07

Developing a computer science-specific learning taxonomy

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2007 Working Group Reports on ITiCSE on Innovation and Technology in computer science Education, ITiCSE-WGR 2007

作者： Fuller, Ursula Johnson, Colin G. Ahoniemi, Tuukka Cukierman, Diana Hernán-Losada, Isidoro Jackova, Jana Lahtinen, Essi Lewis, Tracy L. Thompson, Donna McGee Riedesel, Charles Thompson, Errol Computing Laboratory University of Kent CanterburyCT2 7NF United Kingdom Institute of Software Systems Tampere University of Technology Tampere Finland School of Computing Science Simon Fraser University BurnabyBC Canada Department of Lenguajes Y Sistemas Informáticos Universidad Rey Juan Carlos Madrid Spain Faculty of Management Science and Informatics University of Zilina Zilina Slovakia Department of Information Technology Radford University RadfordVA24142 United States Department of Learning Commons Simon Fraser University BurnabyBC Canada Department of Computer Science and Engineering University of Nebraska Lincoln 259 Avery Hall LincolnNE68588-0115 United States Massey University Wellington New Zealand

ISBN: (纸本)9781450378420

Bloom's taxonomy of the cognitive domain and the SOLO taxonomy are being increasingly widely used in the design and assessment of courses, but there are some drawbacks to their use in computer science. This paper reviews the literature on educational taxonomies and their use in computer science education, identifies some of the problems that arise, proposes a new taxonomy and discusses how this can be used in application-oriented courses such as programming.

关键词： Taxonomies

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REQUIREMENTS FOR AN EVENT-BASED SIMULATION PACKAGE FOR GRID SYSTEMS

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Journal of Interconnection Networks 2007年第2期8卷 163-178页

作者： FATOS XHAFA JAVIER CARRETERO LEONARD BAROLLI ARJAN DURRESI Polytechnic University of Catalonia Department of Languages and Informatics Systems C/Jordi Girona 1-3 08034 Barcelona Spain . Polytechnic University of Catalonia Department of Computer Architecture C/Jordi Girona 1-3 08034 Barcelona Spain Department of Information and Communication Engineering Fukuoka Institute of Technology (FIT) 3-30-1 Wajiro-higashi Higashi-ku Fukuoka 811-0295 Japan Department of Computer Science Louisiana State University 298 Coates Hall Baton Rouge LA 70803 USA

In this paper we present a study on the requirements for the design and implementation of simulation packages for Grid systems. Grids are emerging as new distributed computing systems whose main objective is to manage and allocate geographically distributed computing resources to applications and users in an efficient and transparent manner. Grid systems are at present very difficult and complex to use for experimental studies of large-scale distributed applications. Although the field of simulation of distributed computing systems is mature, recent developments in large-scale distributed systems are raising needs not present in the simulation of the traditional distributed systems. Motivated by this, we present in this work a set of basic requirements that any simulation package for Grid computing should offer. This set of functionalities is obtained after a careful review of most important existing Grid simulation packages and includes new requirements not considered in such simulation packages. Based on the identified set of requirements, a Grid simulator is developed and exemplified for the Grid scheduling problem.

关键词： Grid systems event-based simulation requirements scheduling

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FISH Image Analysis Using a Modified Radial Basis Function Network

FISH Image Analysis Using a Modified Radial Basis Function N...

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International Symposium on Signals, Circuits and Systems (ISSCS)

作者： Ioannis N. Kasampalidis Ioannis Pitas Georgia Karayannopoulou Ioannis Kostopoulos Paolo Aretini Generoso Bevilacqua Andrea Cavazzana Michele Menicagli Antonina Starita Kleoniki Lyroudia Department of Informatics School of Applied Sciences Aristotle University of Thessaloniki Thessaloniki Greece Department of Pathology Medical School Aristotle University of Thessaloniki Thessaloniki Greece Research Institute for Networks and Communications Engineering Radio and Optical Communications Laboratory University of Pisa and Pisa University Hospital Pisa Italy Institute of Molecular Genetics and Medicine MGM Pisa Italy Department of Computer Science Dental School University of Pisa Pisa Italy Department of Endodontology Dental School Aristotle University of Thessaloniki Thessaloniki Greece

Fluorescent in situ hybridization (FISH) is a valuable method for determining Her-2/neu status in breast carcinoma samples, an important prognostic indicator. Visual evaluation of FISH images is a difficult task which involves manual counting of dots in multiple images, a procedure which is both time consuming and prone to human error. A number of algorithms have recently been developed dealing with (semi)-automated analysis of FISH images. These algorithms are quite promising but further improvement is required in improving their accuracy. Here, we present a novel method for analyzing FISH images based on the statistical properties of Radial Basis Functions. Our method was evaluated on a data set of 100 breast carcinoma cases provided by the Aristotle University of Thessaloniki and the University of Pisa, with promising results.

关键词： Marine animals Image analysis Radial basis function networks Breast Image segmentation Fluorescence Pathology Biomedical imaging Performance analysis Morphological operations

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U-Care for the elderly: Implemenation of a Comprehensive Living and Health Care Network

U-Care for the elderly: Implemenation of a Comprehensive Liv...

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International Conference on e-health Networking, Applications and Services (HealthCom)

作者： Heng-Shuen Chen Mei-Ju Su Tsung-Hsueh Tsai Shih-Shung Teng Han-Wei Zhang Jin-Shin Lai Fei-Pei Lai Ching-Yu Chen Department of Medical Informatics National Taiwan University College of Medicine and University Hospital Taipei Taiwan Graduate Institute of Electronics Engineering National Taiwan University Taipei Taiwan Caridinal Tien Hospital Young-Ho Branch Taipei Taiwan Genmart Tech Co. Taipei Taiwan Department of Physical Medicine & Rehabilitation National Taiwan University College of Medicine and University Hospital Taipei Taiwan Dept. of Computer Science & Information Engineering National Taiwan University Taipei Taiwan Department of Family Medicine National Taiwan University College of Medicine and University Hospital Taipei Taiwan

Taiwan started to be an 'aging society' from 1993, and the aging process will progress more rapidly due to markedly decreased child birth in recent year. Facing very high old age dependency ratio as 1 to 2 in year 2030 which means every two working age persons (age 15 - 64 years) have to support one elderly people. That would be an enormous burden for every family and society. In this study a U-Care system was developed and implemented in a satellite city region of Taipei metropolitan area in Taiwan, to provide a comprehensive living and health care service network for the elderly. The u-Health research team of National Taiwan University and Hospital collaborate with Cardinal Tien Hospital Young-Ho Branch, 17 primary care doctors and two living care service provider partners to provide integrated and continuous services for elderly people in home, community and institutional setting.

关键词： Senior citizens medical services Aging Hospitals Educational institutions Cardiac disease Cardiovascular diseases computer science Pediatrics Biomedical informatics

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Features Extraction from Time-Varying Cortical Networks Adopting a Theoretical Graph Approach

Features Extraction from Time-Varying Cortical Networks Adop...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： F. De Vico Fallani L. Astolfi F. Cincotti D. Mattia A. Tocci S. Capitanio MG. Marciani H. Salinari W. Hesse H. Witte S. Gao A. Colosimo F. Babiloni Interdepartmental Research Centre for Models and Information Analysis in Biomedical Systems University “Sapienza” Rome Italy IRCCS “Fondazione Santa Lucia” Rome Italy Department of Neuroscience University “Tor Vergata” Rome Italy Department of Neuroscience University of Roma Tor Vergata Rome Italy Department of Computer and Systems Science University “Sapienza” Rome Italy Institute of Medical Statistics Computer Sciences and Documentation Friedrich Schiller University of Jena Jena Germany Department of Biomedical Engineering Tsinghua University Beijing China Department of Human Physiology and Pharmacology University “Sapienza” Rome Italy

In this work, a novel approach is proposed in order to capture relevant features related to the structure and organization of the functional brain networks estimated in the time-frequency domain. To achieve this, we used a cascade of computational tools able to estimate first the electrical activity of the cortical surface by using high resolution EEG techniques. Then, on the cortical signals from different regions of interests we estimated the time-varying functional connectivity patterns by means of the adaptive partial directed coherence. Such time-varying connectivity estimation returns a series of causality patterns evolving during the examined task which can be summarized and interpreted with the aid of mathematical indexes based on the graph theory. The combination of all these methods is demonstrated on a set of high resolution EEG data recorded from a healthy subject performing a simple foot movement.

关键词： Feature extraction Electroencephalography Brain modeling Neuroscience Biomedical computing Complex networks Frequency estimation Frequency domain analysis Spatial resolution Magnetic heads

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