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Author Correction: BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

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Nature methods 2024年第10期21卷 1959页

作者： Linus Manubens-Gil Zhi Zhou Hanbo Chen Arvind Ramanathan Xiaoxiao Liu Yufeng Liu Alessandro Bria Todd Gillette Zongcai Ruan Jian Yang Miroslav Radojević Ting Zhao Li Cheng Lei Qu Siqi Liu Kristofer E Bouchard Lin Gu Weidong Cai Shuiwang Ji Badrinath Roysam Ching-Wei Wang Hongchuan Yu Amos Sironi Daniel Maxim Iascone Jie Zhou Erhan Bas Eduardo Conde-Sousa Paulo Aguiar Xiang Li Yujie Li Sumit Nanda Yuan Wang Leila Muresan Pascal Fua Bing Ye Hai-Yan He Jochen F Staiger Manuel Peter Daniel N Cox Michel Simonneau Marcel Oberlaender Gregory Jefferis Kei Ito Paloma Gonzalez-Bellido Jinhyun Kim Edwin Rubel Hollis T Cline Hongkui Zeng Aljoscha Nern Ann-Shyn Chiang Jianhua Yao Jane Roskams Rick Livesey Janine Stevens Tianming Liu Chinh Dang Yike Guo Ning Zhong Georgia Tourassi Sean Hill Michael Hawrylycz Christof Koch Erik Meijering Giorgio A Ascoli Hanchuan Peng Institute for Brain and Intelligence Southeast University Nanjing China. Microsoft Corporation Redmond WA USA. Tencent AI Lab Bellevue WA USA. Computing Environment and Life Sciences Directorate Argonne National Laboratory Lemont IL USA. Kaya Medical Seattle WA USA. University of Cassino and Southern Lazio Cassino Italy. Center for Neural Informatics Structures and Plasticity Krasnow Institute for Advanced Study George Mason University Fairfax VA USA. Faculty of Information Technology Beijing University of Technology Beijing China. Beijing International Collaboration Base on Brain Informatics and Wisdom Services Beijing China. Nuctech Netherlands Rotterdam the Netherlands. Janelia Research Campus Howard Hughes Medical Institute Ashburn VA USA. Department of Electrical and Computer Engineering University of Alberta Edmonton Alberta Canada. Ministry of Education Key Laboratory of Intelligent Computation and Signal Processing Anhui University Hefei China. Paige AI New York NY USA. Scientific Data Division and Biological Systems and Engineering Division Lawrence Berkeley National Lab Berkeley CA USA. Helen Wills Neuroscience Institute and Redwood Center for Theoretical Neuroscience UC Berkeley Berkeley CA USA. RIKEN AIP Tokyo Japan. Research Center for Advanced Science and Technology (RCAST) The University of Tokyo Tokyo Japan. School of Computer Science University of Sydney Sydney New South Wales Australia. Texas A&M University College Station TX USA. Cullen College of Engineering University of Houston Houston TX USA. Graduate Institute of Biomedical Engineering National Taiwan University of Science and Technology Taipei Taiwan. National Centre for Computer Animation Bournemouth University Poole UK. PROPHESEE Paris France. Department of Neuroscience Columbia University New York NY USA. Mortimer B. Zuckerman Mind Brain Behavior Institute Columbia University New York NY USA. Department of Computer Science Northern Illinois Universit

Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021

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The Lancet Public Health 2025年第3期10卷 e172-e188页

作者： Steel, Nicholas Bauer-Staeb, Clarissa Maria Mercedes Ford, John A. Abbafati, Cristiana Abdalla, Mohammed Altigani Abdelkader, Atef Abdi, Parsa Zuñiga, Roberto Ariel Abeldaño Abiodun, Olugbenga Olusola Abolhassani, Hassan Abu-Gharbieh, Eman Abukhadijah, Hana J. Abu-Zaid, Ahmed Addo, Isaac Yeboah Addolorato, Giovanni Adekanmbi, Victor Adetunji, Juliana Bunmi Adeyeoluwa, Temitayo Esther Agardh, Emilie E. Agyemang-Duah, Williams Ahmad, Danish Ahmed, Ayman Ahmed, Syed Anees Akinosoglou, Karolina Akkaif, Mohammed Ahmed Al Awaidy, Salah Al Hasan, Syed Mahfuz Al Zaabi, Omar Ali Mohammed Aldridge, Robert W. Algammal, Abdelazeem M. Al-Gheethi, Adel Ali Saeed Ali, Abid Ali, Mohammed Usman Ali, Syed Shujait Ali, Waad Alicandro, Gianfranco Alif, Sheikh Mohammad Al-Jumaily, Adel Allebeck, Peter Alrawashdeh, Ahmad Al-Rifai, Rami H. Alsabri, Mohammed A. Alshahrani, Najim Z. Aluh, Deborah Oyine Al-Wardat, Mohammad Al-Zyoud, Walid A. Amiri, Sohrab Anderlini, Deanna Andrei, Catalina Liliana Anil, Abhishek Anvari, Saeid Anyasodor, Anayochukwu Edward Appiah, Seth Christopher Yaw Aquilano, Michele Arabloo, Jalal Arafat, Mosab Areda, Demelash Aremu, Abdulfatai Armani, Keivan Armocida, Benedetta Ärnlöv, Johan Asaduzzaman, Muhammad Astell-Burt, Thomas Aujayeb, Avinash Ausloos, Marcel Azadnajafabad, Sina Aziz, Shahkaar Azzam, Ahmed Y. Babu, Giridhara Rathnaiah Badache, Andreea Corina Badiye, Ashish D. Bahramian, Saeed Baig, Atif Amin Baker, Jennifer L. Bansal, Hansi Bärnighausen, Till Winfried Barone, Mark Thomaz Ugliara Barrow, Amadou Barteit, Sandra Bashir, Shahid Bashiru, Hameed Akande Basso, João Diogo Bastan, Mohammad-Mahdi Basu, Sanjay Batra, Kavita Bauckneht, Matteo Baune, Bernhard T. Beghi, Massimiliano Beiranvand, Maryam Béjot, Yannick Bell, Michelle L. Bello, Olorunjuwon Omolaja Belo, Luis Beloukas, Apostolos Beneke, Alice A. Bettencourt, Paulo J.G. Bhagavathula, Akshaya Srikanth Bhala, Neeraj Bhaskar, Sonu Bisulli, Francesca Bjørge, Tone Bodunrin, Aadam Olalekan Carvajal, Alejandro Botero Bouaoud, Souad Brayne, Carol Brenner, H Department of Primary Care and Public Health University of East Anglia Norwich United Kingdom Office for Health Improvement and Disparities Department of Health and Social Care London United Kingdom Department of Legal and Economic Studies La Sapienza University Rome Italy Rome Italy Hull York Medical School University of Hull Hull United Kingdom Department of Mathematics and Sciences Ajman University Ajman United Arab Emirates Department of Medicine Memorial University St. John's NL Canada Postgraduate Department University of Sierra Sur Miahuatlan de Porfirio Diaz Mexico Yhteiskuntadatatieteen keskus (Centre for Social Data Science) Helsinki Finland Department of Internal Medicine Federal Medical Centre Abuja Nigeria Research Center for Immunodeficiencies Tehran University of Medical Sciences Tehran Iran Department of Medical Biochemistry and Biophysics Karolinska Institutet (Karolinska Institute) Stockholm Sweden Department of Clinical Sciences University of Sharjah Sharjah United Arab Emirates Department of Biopharmaceutics and Clinical Pharmacy University of Jordan Amman Jordan Medical Research Center Hamad Medical Corporation Doha Qatar Department of Biochemistry and Molecular Medicine Alfaisal University Riyadh Saudi Arabia College of Graduate Health Sciences University of Tennessee Memphis TN United States School of Medicine Sydney NSW Australia Centre for Social Research in Health University of New South Wales Sydney NSW Australia Internal Medicine and Alcohol Related Disease Unit Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy Department of Medical and Surgical Sciences Università Cattolica di Roma (Catholic University of Rome) Rome Italy Department of Obstetrics and Gynecology University of Texas Medical Branch Galveston TX United States Department of Biochemistry Osun State University Osogbo Nigeria Department of Pharmacology and Therapeutics University of Medical Sciences Ondo Ondo Nigeria Department of Veteri

Background: Decades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and cause-specific death rates in different European countries related to changes in life expectancy in those countries before and during the COVID-19 pandemic. Methods: We used data and methods from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to compare changes in life expectancy at birth, causes of death, and population exposure to risk factors in 16 European Economic Area countries (Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, and Sweden) and the four UK nations (England, Northern Ireland, Scotland, and Wales) for three time periods: 1990–2011, 2011–19, and 2019–21. Changes in life expectancy and causes of death were estimated with an established life expectancy cause-specific decomposition method, and compared with summary exposure values of risk factors for the major causes of death influencing life expectancy. Findings: All countries showed mean annual improvements in life expectancy in both 1990–2011 (overall mean 0·23 years [95% uncertainty interval [UI] 0·23 to 0·24]) and 2011–19 (overall mean 0·15 years [0·13 to 0·16]). The rate of improvement was lower in 2011–19 than in 1990–2011 in all countries except for Norway, where the mean annual increase in life expectancy rose from 0·21 years (95% UI 0·20 to 0·22) in 1990–2011 to 0·23 years (0·21 to 0·26) in 2011–19 (difference of 0·03 years). In other countries, the difference in mean annual improvement between these periods ranged from –0·01 years in Iceland (0·19 years [95% UI 0·16 to 0·21] vs 0·18 years [0·09 to 0·26]), to –0·18 years in England (0·25 years [0·24 to 0·25] vs 0·07 years [0·06 to 0·08]). In 2019–21, there was an overall decrease in mean annual life expectancy a

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SPT clusters with DES and HST weak lensing. I. Cluster lensing and Bayesian population modeling of multiwavelength cluster datasets

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Physical Review D 2024年第8期110卷 083509页

作者： S. Bocquet S. Grandis L. E. Bleem M. Klein J. J. Mohr M. Aguena A. Alarcon S. Allam S. W. Allen O. Alves A. Amon B. Ansarinejad D. Bacon M. Bayliss K. Bechtol M. R. Becker B. A. Benson G. M. Bernstein M. Brodwin D. Brooks A. Campos R. E. A. Canning J. E. Carlstrom A. Carnero Rosell M. Carrasco Kind J. Carretero R. Cawthon C. Chang R. Chen A. Choi J. Cordero M. Costanzi L. N. da Costa M. E. S. Pereira C. Davis J. DeRose S. Desai T. de Haan J. De Vicente H. T. Diehl S. Dodelson P. Doel C. Doux A. Drlica-Wagner K. Eckert J. Elvin-Poole S. Everett I. Ferrero A. Ferté A. M. Flores J. Frieman J. García-Bellido M. Gatti G. Giannini M. D. Gladders D. Gruen R. A. Gruendl I. Harrison W. G. Hartley K. Herner S. R. Hinton D. L. Hollowood W. L. Holzapfel K. Honscheid N. Huang E. M. Huff D. J. James M. Jarvis G. Khullar K. Kim R. Kraft K. Kuehn N. Kuropatkin F. Kéruzoré S. Lee P.-F. Leget N. MacCrann G. Mahler A. Mantz J. L. Marshall J. McCullough M. McDonald J. Mena-Fernández R. Miquel J. Myles A. Navarro-Alsina R. L. C. Ogando A. Palmese S. Pandey A. Pieres A. A. Plazas Malagón J. Prat M. Raveri C. L. Reichardt J. Roberson R. P. Rollins A. K. Romer C. Romero A. Roodman A. J. Ross E. S. Rykoff L. Salvati C. Sánchez E. Sanchez D. Sanchez Cid A. Saro T. Schrabback M. Schubnell L. F. Secco I. Sevilla-Noarbe K. Sharon E. Sheldon T. Shin M. Smith T. Somboonpanyakul B. Stalder A. A. Stark V. Strazzullo E. Suchyta M. E. C. Swanson G. Tarle C. To M. A. Troxel I. Tutusaus T. N. Varga A. von der Linden N. Weaverdyck J. Weller P. Wiseman B. Yanny B. Yin M. Young Y. Zhang J. Zuntz University Observatory Faculty of Physics Universität Innsbruck Institut für Astro- und Teilchenphysik Technikerstr. 25/8 6020 Innsbruck Austria Argonne National Laboratory 9700 South Cass Avenue Lemont Illinois 60439 USA Kavli Institute for Cosmological Physics University of Chicago Chicago Illinois 60637 USA Max Planck Institute for Extraterrestrial Physics Gießenbachstr. 1 85748 Garching Germany Laboratório Interinstitucional de e-Astronomia - LIneA Rua Gal. José Cristino 77 Rio de Janeiro RJ-20921-400 Brazil Fermi National Accelerator Laboratory P. O. Box 500 Batavia Illinois 60510 USA Kavli Institute for Particle Astrophysics and Cosmology Stanford University 452 Lomita Mall Stanford California 94305 USA Department of Physics Stanford University 382 Via Pueblo Mall Stanford California 94305 USA SLAC National Accelerator Laboratory 2575 Sand Hill Road Menlo Park California 94025 USA Department of Physics University of Michigan Ann Arbor Michigan 48109 USA Institute of Astronomy University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom Kavli Institute for Cosmology University of Cambridge Madingley Road Cambridge CB3 0HA United Kingdom School of Physics University of Melbourne Parkville Victoria 3010 Australia Institute of Cosmology and Gravitation University of Portsmouth Portsmouth PO1 3FX United Kingdom Department of Physics University of Cincinnati Cincinnati Ohio 45221 USA Physics Department 2320 Chamberlin Hall University of Wisconsin-Madison 1150 University Avenue Madison Wisconsin 53706-1390 USA Department of Astronomy and Astrophysics University of Chicago Chicago Illinois 60637 USA Fermi National Accelerator Laboratory Batavia Illinois 60510-0500 USA Department of Physics and Astronomy University of Pennsylvania Philadelphia Pennsylvania 19104 USA Department of Physics and Astronomy University of Missouri 5110 Rockhill Road Kansas City Missouri 64110 USA Department of Physics and Astronomy University Coll

We present a Bayesian population modeling method to analyze the abundance of galaxy clusters identified by the South Pole Telescope (SPT) with a simultaneous mass calibration using weak gravitational lensing data from the Dark Energy Survey (DES) and the Hubble Space Telescope (HST). We discuss and validate the modeling choices with a particular focus on a robust, weak-lensing-based mass calibration using DES data. For the DES Year 3 data, we report a systematic uncertainty in weak-lensing mass calibration that increases from 1% at z=0.25 to 10% at z=0.95, to which we add 2% in quadrature to account for uncertainties in the impact of baryonic effects. We implement an analysis pipeline that joins the cluster abundance likelihood with a multiobservable likelihood for the Sunyaev-Zel’dovich effect, optical richness, and weak-lensing measurements for each individual cluster. We validate that our analysis pipeline can recover unbiased cosmological constraints by analyzing mocks that closely resemble the cluster sample extracted from the SPT-SZ, SPTpol ECS, and SPTpol 500d surveys and the DES Year 3 and HST-39 weak-lensing datasets. This work represents a crucial prerequisite for the subsequent cosmological analysis of the real dataset.

关键词： Cosmological parameters Gravitational lenses Large scale structure of the Universe

Online Educational Resources Classification Using Visual Features

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Online Educational Resources Classification Using Visual Fea...

International Conference on Digital Home (ICDH)

作者： Xiangping Chen Yancheng Chen Yonghao Long Yongsheng Rao Hao Guan Mouguang Lin School of Data Science and Computer Sun Yat-sen University Guangzhou China University of Chinese Academy of Sciences Beijing China Institute of Computing Science and Technology Guangzhou University Guangzhou China

With the promotion of the Internet, people can easily retrieve various kinds of education resources on the web. However, current education resources sharing platforms do not support the resources retrieval through the visual information. Therefore, we need to classify the resources which are related to visual characteristics into several categories. In this paper, we propose a novel classification method for resources on Netpad[ http://***/]. We extract the important visual features including graphics features and text features. Then, we use the random forest algorithm to train a valuable model. The results of the experiments indicate that, using graphics features and text features, most of the data are classified correctly, which means that our proposed method can solve the classification problem of Netpad effectively.

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Balanced distribution adaptation for transfer learning

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arXiv 2018年

作者： Wang, Jindong Chen, Yiqiang Hao, Shuji Feng, Wenjie Shenk, Zhiqi Beijing Key Laboratory of Mobile Computing and Pervasive Device CAS Key Laboratory of Network Data Science and Technology Institute of Computing Technology Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Institute of High Performance Computing A*STAR School of Computer Science and Engineering Nanyang Technological University Singapore Singapore

Transfer learning has achieved promising results by leveraging knowledge from the source domain to annotate the target domain which has few or none labels. Existing methods often seek to minimize the distribution divergence between domains, such as the marginal distribution, the conditional distribution or both. However, these two distances are often treated equally in existing algorithms, which will result in poor performance in real applications. Moreover, existing methods usually assume that the dataset is balanced, which also limits their performances on imbalanced tasks that are quite common in real problems. To tackle the distribution adaptation problem, in this paper, we propose a novel transfer learning approach, named as Balanced Distribution Adaptation (BDA), which can adaptively leverage the importance of the marginal and conditional distribution discrepancies, and several existing methods can be treated as special cases of BDA. Based on BDA, we also propose a novel Weighted Balanced Distribution Adaptation (W-BDA) algorithm to tackle the class imbalance issue in transfer learning. W-BDA not only considers the distribution adaptation between domains but also adaptively changes the weight of each class. To evaluate the proposed methods, we conduct extensive experiments on several transfer learning tasks, which demonstrate the effectiveness of our proposed algorithms over several state-of-the-art methods. Copyright © 2018, The Authors. All rights reserved.

关键词： Learning algorithms

Lecture Notes in Electrical Engineering

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Preface

Lecture Notes in Electrical Engineering 2020年 603卷 v-vi页

作者： Alfred, Rayner Haviluddin, Haviluddin Lim, Yuto On, Chin Kim Knowledge Technology Research Unit Faculty of Computing and Informatics Universiti Malaysia Sabah Kota KinabaluSabah Malaysia Department of Computer Science Universitas Mulawarman Samarinda Indonesia School of Information Science Security and Networks Area Japan Advanced Institute of Science and Technology Nomi Ishikawa Japan Center of Data and Information Management Universiti Malaysia Sabah Kota KinabaluSabah Malaysia

A quantum annealing approach to ionic diffusion in solids

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arXiv 2019年

作者： Utimula, Keishu Ichibha, Tom Prayogo, Genki I. Hongo, Kenta Nakano, Kousuke Maezono, Ryo School of Materials Science JAIST Asahidai 1-1 Nomi Ishikawa923-1292 Japan School of Information Science JAIST Asahidai 1-1 Nomi Ishikawa923-1292 Japan Research Center for Advanced Computing Infrastructure JAIST Asahidai 1-1 Nomi Ishikawa923-1292 Japan Center for Materials Research by Information Integration Research and Services Division of Materials Data and Integrated System National Institute for Materials Science Tsukuba305-0047 Japan PRESTO Japan Science and Technology Agency 4-1-8 Honcho Kawaguchi-shi Saitama322-0012 Japan

We have developed a framework for using quantum annealing computation to evaluate a key quantity in ionic diffusion in solids, the correlation factor. Existing methods can only calculate the correlation factor analytically in the case of physically unrealistic models, making it difficult to relate microstructural information about diffusion path networks obtainable by current ab initio techniques to macroscopic quantities such as diffusion coefficients. We have mapped the problem into a quantum spin system described by the Ising Hamiltonian. By applying our framework in combination with ab initio technique, it is possible to understand how diffusion coefficients are controlled by temperatures, pressures, atomic substitutions, and other factors. We have calculated the correlation factor in a simple case with a known exact result by a variety of computational methods, including simulated quantum annealing on the spin models, the classical random walk, the matrix description, and quantum annealing on D-Wave with hybrid solver. This comparison shows that all the evaluations give consistent results with each other, but that many of the conventional approaches require infeasible computational costs. Quantum annealing is also currently infeasible because of the cost and scarcity of Q-bits, but we argue that when technological advances alter this situation, quantum annealing will easily outperform all existing methods. Copyright © 2019, The Authors. All rights reserved.

关键词： Hamiltonians

Stochastic estimations of a total number of classes for the clusterings with too enormous samples to be accommodate into a clustering engine

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arXiv 2019年

作者： Utimula, Keishu Prayogo, Genki I. Nakano, Kousuke Hongo, Kenta Maezono, Ryo School of Materials Science JAIST Asahidai 1-1 Nomi Ishikawa923-1292 Japan School of Information Science JAIST Asahidai 1-1 Nomi Ishikawa923-1292 Japan Research Center for Advanced Computing Infrastructure JAIST Asahidai 1-1 Nomi Ishikawa923-1292 Japan Center for Materials Research by Information Integration Research and Services Division of Materials Data and Integrated System National Institute for Materials Science Tsukuba305-0047 Japan PRESTO Japan Science and Technology Agency 4-1-8 Honcho Kawaguchi-shi Saitama322-0012 Japan

We considered the problem how to handle the exploding number of possibilities to be sorted into irreducible classes by using a clustering tool when its input capacity cannot accommodate the total number of the possibility. Concrete situations are explained taking examples of atomic substitutions in the supercell modeling of alloys. The number of the possibility sometimes amounts to ∼ trillion being too large to be accommodate. It is hence not practically feasible to identify how many irreducible classes exist by straightforward manner even though there are several tools available to perform the clustering. We have developed a stochastic framework to avoid the shortage of capacity, providing a method to estimate the total number of irreducible classes (the order of the classes) as a statistical estimate. A prominent conclusion derived here is that the statistical variation of the number of classes at each sampling trial is working as a promising measure to estimate the order. Copyright © 2019, The Authors. All rights reserved.

关键词： Stochastic systems

VerSe: A Vertebrae Labelling and Segmentation Benchmark for Multi-detector CT Images

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arXiv 2020年

作者： Sekuboyina, Anjany Kumar Husseini, Malek E. Bayat, Amirhossein Löffler, Maximilian Liebl, Hans Li, Hongwei Tetteh, Giles Kukačka, Jan Payer, Christian Štern, Darko Urschler, Martin Chen, Maodong Cheng, Dalong Lessmann, Nikolas Hu, Yujin Wang, Tianfu Yang, Dong Xu, Daguang Ambellan, Felix Amiranashvili, Tamaz Ehlke, Moritz Lamecker, Hans Lehnert, Sebastian Lirio, Marilia de Olaguer, Nicolás Pérez Ramm, Heiko Sahu, Manish Tack, Alexander Zachow, Stefan Jiang, Tao Ma, Xinjun Angerman, Christoph Wang, Xin Brown, Kevin Kirszenberg, Alexandre Puybareau, Élodie Chen, Di Bai, Yiwei Rapazzo, Brandon H. Yeah, Timyoas Zhang, Amber Xu, Shangliang Hou, Feng He, Zhiqiang Zeng, Chan Xiangshang, Zheng Liming, Xu Netherton, Tucker J. Mumme, Raymond P. Court, Laurence E. Huang, Zixun He, Chenhang Wang, Li-Wen Ling, Sai Ho Huynh, Lê Duy Boutry, Nicolas Jakubicek, Roman Chmelik, Jiri Mulay, Supriti Sivaprakasam, Mohanasankar Paetzold, Johannes C. Shit, Suprosanna Ezhov, Ivan Wiestler, Benedikt Glocker, Ben Valentinitsch, Alexander Rempfler, Markus Menze, Björn H. Kirschke, Jan S. Department of Informatics Technical University of Munich Germany Munich School of BioEngineering Technical University of Munich Germany Department of Neuroradiology Klinikum Rechts der Isar Germany Department for Quantitative Biomedicine University of Zurich Switzerland Friedrich Miescher Institute for Biomedical Engineering Switzerland Institute of Biological and Medical Imaging Helmholtz Zentrum München Germany Department of Computing Imperial College London United Kingdom Institute of Computer Graphics and Vision Graz University of Technology Austria Gottfried Schatz Research Center: Biophysics Medical University of Graz Austria School of Computer Science The University of Auckland New Zealand Computer Vision Group iFLYTEK Research South China China Department of Radiology and Nuclear Medicine Radboud University Medical Center Nijmegen Netherlands Shenzhen Research Institute of Big Data China School of Biomedical Engineering Health Science Center Shenzhen University China NVIDIA Corporation United States Zuse Institute Berlin Germany 1000shapes GmbH Berlin Germany Damo Academy Alibaba Group China Department of Mathematics University of Innsbruck Austria Department of Electronic Engineering Fudan University China New York University United States France Deep Reasoning AI Inc United States Technical University of Munich Germany East China Normal University China Chinese Academy of Sciences China Lenovo Group China Ping An Technologies China College of Computer Science and Technology Zhejiang University China Real Doctor AI Research Centre Zhejiang University China The University of Texas MD Anderson Cancer Center United States Department of Electronic and Information Engineering The Hong Kong Polytechnic University China Department of Computing The Hong Kong Polytechnic University China The School of Biomedical Engineering University of Technology Sydney Australia Department of Biomedical Engineering Brno University of Technology Czech Republic India

Vertebral labelling and segmentation are two fundamental tasks in an automated spine processing pipeline. Reliable and accurate processing of spine images is expected to benefit clinical decision support systems for diagnosis, surgery planning, and population-based analysis of spine and bone health. However, designing automated algorithms for spine processing is challenging predominantly due to considerable variations in anatomy and acquisition protocols and due to a severe shortage of publicly available data. Addressing these limitations, the Large Scale Vertebrae Segmentation Challenge (VerSe) was organised in conjunction with the International Conference on Medical Image computing and Computer Assisted Intervention (MICCAI) in 2019 and 2020, with a call for algorithms tackling the labelling and segmentation of vertebrae. Two datasets containing a total of 374 multi-detector CT scans from 355 patients were prepared and 4505 vertebrae have individually been annotated at voxel level by a human-machine hybrid algorithm (https://***/nqjyw/, https://***/t98fz/). A total of 25 algorithms were benchmarked on these datasets. In this work, we present the results of this evaluation and further investigate the performance variation at the vertebra level, scan level, and different fields of view. We also evaluate the generalisability of the approaches to an implicit domain shift in data by evaluating the top-performing algorithms of one challenge iteration on data from the other iteration. The principal takeaway from VerSe: the performance of an algorithm in labelling and segmenting a spine scan hinges on its ability to correctly identify vertebrae in cases of rare anatomical variations. The VerSe content and code can be accessed at: https://***/anjany/verse. © 2020, CC BY-NC-ND.

关键词： Computerized tomography