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Medical Imaging 2025: Digital and Computational Pathology

作者： Kopriva, Ivica Dion-Bertrand, Laura-Isabelle Pačić, Arijana Periša, Marija Milković Hadžija, Marijana Popović Hadžija, Mirko Sitnik, Dario Division of Computing and Data Science Ruđer Bošković Institute Bijenička cesta 54 P.O. Box 180 Zagreb10002 Croatia Department of Physics University of Montreal MontrealQCH2V OB3 Canada Department of Pathology and Cytology Clinical Hospital Dubrava Avenija Gojka Šuška 6 Zagreb10000 Croatia Clinical Hospital Center Zagreb Kišpatićeva 12 Zagreb10000 Croatia Institute of pathology School of Medicine University of Zagreb Šalata 3 Zagreb10000 Croatia Division of Molecular Medicine Ruđer Bošković Institute Bijenička cesta 54 Zagreb10000 Croatia School of Computation Information and Technology Technical University Munich Munich Germany

ISBN: (纸本)9781510686045

Hyperspectral imaging (HSI) is a spatial-spectral modality with significant potential in disease diagnosis and surgical cancer resection. In this case study, we explore the use of two-mode (bright field-BF and dark field-DF) HSI for pixel-wise classification of adenocarcinoma of the colon in the liver, utilizing two co-registered pairs of HSIs from hematoxylin and eosin stained histopathological specimens. They were collected from two patients during intraoperative frozen section analysis. We trained a two-layer perceptron on one pair of concatenated BF and DF HSIs and used it to classify concatenated HSIs of another pair, and vice versa. We then compared the performance against the corresponding bright field HSI as a baseline. The pixel-wise ground truth was established through a majority vote from annotations provided by two pathologists and one medical expert. After twenty evaluations, achieved balanced accuracy and F1 score were: 74.06% ± 3.73% and 63.43% ± 3.80% for two-mode HSIs, and 71.36% ± 3.74% and 62.30% ± 10.82% for bright field HSI. Statistically significant improvement in balanced accuracy with a p value of 0.009 was performed by a two-sample t-test, after the samples passed the Shapiro-Wilk test for normality, and with a p value of 0.022 by a Wilcoxon sum-rank test. While definitive conclusions cannot be made based on results from only two pairs of HSIs from two patients, these findings justify the design and conduction of a more comprehensive study based on co-registered pairs of BF and DF hyperspectral images. © 2025 SPIE.

关键词： Fractography

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Provably Secure Efficient Key-Exchange Protocol for Intelligent Supply Line Surveillance in Smart Grids

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IEEE Internet of Things Journal 2025年

作者： Ayub, Muhammad Faizan Li, Xiong Mahmood, Khalid Alenazi, Mohammed J.F. Das, Ashok Kumar Wang, Guijuan University of Electronic Science and Technology of China School of Computer Science and Engineering Sichuan Chengdu12599 China National Yunlin University of Science and Technology Graduate School of Intelligent Data Science Yunlin Douliu64002 Taiwan Department of Computer Engineering Riyadh11451 Saudi Arabia International Institute of Information Technology Center for Security Theory and Algorithmic Research Hyderabad500 032 India Korea University College of Informatics Department of Computer Science and Engineering Anam-ro Seoul145 Korea Republic of Ministry of Education Shandong Computer Science Center Qilu University of Technology Shandong Academy of Sciences Key Laboratory of Computing Power Network and Information Security Jinan250353 China Shandong Provincial Key Laboratory of Industrial Network and Information System Security China Shandong Fundamental Research Center for Computer Science Jinan 250353 China

Intelligent supply line surveillance is critical for modern smart grids. Smart sensors and gateway nodes are strategically deployed along supply lines to achieve intelligent surveillance. They collect data continuously and transmit it to the control centre in real-time. It enables real-time monitoring, fault detection, and efficient energy management across distribution networks. This advanced surveillance system ensures continuous monitoring of supply lines, detecting anomalies, and optimizing operations to maintain the stability and reliability of the smart grid. However, the reliance of all participating nodes on public communication channels to transmit supply line surveillance data exposes these systems to critical cyber attacks. These cyber attacks include impersonation, physical tampering, ephemeral secret leakage, and desynchronization attacks. To address these issues, existing key-exchange protocols often fail to ensure robust security while imposing high computation and communication overheads, limiting their practicality for resource-constrained environments. Therefore, we propose a secure and efficient key exchange and tamper-resistant authentication protocol using Elliptic Curve Cryptography (ECC) and Physical Unclonable Functions (PUFs). The PUF mechanism provides robust resistance against physical tampering and cloning attacks, ensuring enhanced physical security for supply line devices. We validate the security robustness of the devised protocol using the Random or Real (ROR) model. Furthermore, informal security analysis demonstrates the protocol's robustness in rigorously resisting various attacks, including physical tampering, impersonation, ephemeral secret leakage and desynchronization. Moreover, we determine the performance evaluation that reveals the protocol's superior efficiency compared to competing protocols, achieving significant reductions of 28.64% in computation overhead and 9.96% in communication overhead. © 2014 IEEE.

关键词： Authentication Protocol

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Fusing Bluetooth with Pedestrian Dead Reckoning: A Floor Plan-Assisted Positioning Approach

arXiv

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arXiv 2025年

作者： Pan, Wenxuan Yang, Yang Chen, Mingzhe Wei, Dong Guo, Caili Mao, Shiwen Beijing Key Laboratory of Network System Architecture and Convergence School of Information and Communication Engineering Beijing University of Posts and Telecommunications Beijing100876 China Department of Electrical and Computer Engineering the Institute for Data Science and Computing University of Miami Coral GablesFL33146 United States Institute of Information Engineering Chinese Academy of Sciences Beijing100093 China Beijing Laboratory of Advanced Information Networks School of Information and Communication Engineering Beijing University of Posts and Telecommunications Beijing100876 China Wireless Engineering Research and Education Center Auburn University AuburnAL36849 United States

Floor plans can provide valuable prior information that helps enhance the accuracy of indoor positioning systems. However, existing research typically faces challenges in efficiently leveraging floor plan information and applying it to complex indoor layouts. To fully exploit information from floor plans for positioning, we propose a floor plan-assisted fusion positioning algorithm (FP-BP) using Bluetooth low energy (BLE) and pedestrian dead reckoning (PDR). In the considered system, a user holding a smartphone walks through a positioning area with BLE beacons installed on the ceiling, and can locate himself in real time. In particular, FP-BP consists of two phases. In the offline phase, FP-BP programmatically extracts map features from a stylized floor plan based on their binary masks, and constructs a mapping function to identify the corresponding map feature of any given position on the map. In the online phase, FP-BP continuously computes BLE positions and PDR results from BLE signals and smartphone sensors, where a novel grid-based maximum likelihood estimation (GML) algorithm is introduced to enhance BLE positioning. Then, a particle filter is used to fuse them and obtain an initial estimate. Finally, FP-BP performs post-position correction to obtain the final position based on its specific map feature. Experimental results show that FP-BP can achieve a real-time mean positioning accuracy of 1.19 m, representing an improvement of over 28% compared to existing floor plan-fused baseline algorithms. Copyright © 2025, The Authors. All rights reserved.

关键词： Photomapping

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From Pixels to Histopathology: A Graph-Based Framework for Interpretable Whole Slide Image Analysis

arXiv

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arXiv 2025年

作者： Weers, Alexander Berger, Alexander H. Lux, Laurin Schüffler, Peter Rueckert, Daniel Paetzold, Johannes C. School of Computation Information and Technology Technical University of Munich Germany Department of Computing Imperial College London United Kingdom Munich Center of Machine Learning Germany Munich Data Science Institute Technical University of Munich Munich Germany Institute of Pathology TUM School of Medicine and Health Technical University of Munich Munich Germany Weill Cornell Medicine Cornell University New York CityNY United States

The histopathological classification of whole-slide images (WSIs) is a fundamental task in digital pathology;yet it requires extensive time and expertise from specialists. While deep learning methods show promising results, they typically process WSIs by dividing them into artificial patches, which inherently prevents a network from learning from the entire image context, disregards natural tissue structures and compromises interpretability. Our method overcomes this limitation through a novel graph-based framework that constructs WSI graph representations. The WSI-graph efficiently captures essential histopathological information in a compact form. We build tissue representations (nodes) that follow biological boundaries rather than arbitrary patches all while providing interpretable features for explainability. Through adaptive graph coarsening guided by learned embeddings, we progressively merge regions while maintaining discriminative local features and enabling efficient global information exchange. In our method’s final step, we solve the diagnostic task through a graph attention network. We empirically demonstrate strong performance on multiple challenging tasks such as cancer stage classification and survival prediction, while also identifying predictive factors using Integrated Gradients. Our implementation is publicly available at https://***/HistoGraph31/pix2pathology © 2025, CC BY.

关键词： Classification (of information)

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DRL-Based Time-Varying Workload Scheduling With Priority and Resource Awareness

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IEEE Transactions on Network and Service Management 2025年

作者： Liu, Qifeng Fan, Qilin Zhang, Xu Li, Xiuhua Wang, Kai Xiong, Qingyu Chongqing University School of Big Data and Software Engineering Chongqing400044 China Chongqing University Key Laboratory of Dependable Service Computing in Cyber Physical Society of Ministry of Education Chongqing400044 China Nanjing University School of Electronic Science and Engineering Nanjing210023 China Haihe Laboratory of Information Technology Application Innovation Tianjin300072 China Harbin Institute of Technology School of Computer Science and Technology Weihai264209 China Shandong Key Laboratory of Industrial Network Security Weihai264209 China

With the proliferation of cloud services and the continuous growth in enterprises' demand for dynamic multi-dimensional resources, the implementation of effective strategy for time-varying workload scheduling has become increasingly significant. In this paper, we propose a deep reinforcement learning (DRL)-based method for time-varying workload scheduling, aiming to allocate resources efficiently across servers in the cluster. Specifically, we integrate a classifier and queue scorer to construct a priority queue that exploits temporal resource utilization patterns across different workload classes. Then, we design parallel graph attention layers to capture the dimensional features and temporal dynamics of cloud server cluster. Moreover, we propose a DRL algorithm to generate scheduling strategies that can adapt to dynamic environments. Validation on real-world traces from Google cluster demonstrates that our method outperforms existing approaches in key metrics of cloud server cluster management. © 2004-2012 IEEE.

关键词： Cloud platforms

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Efficient COVID-19 detection using data mining algorithms: a comparison of basic and hybrid approaches

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Soft computing 2025年第3期29卷 1437-1451页

作者： Saidi, Mohammad Gheibi, Mohammad Ghazikhani, Adel Lotfata, Aynaz Chahkandi, Benyamin Familsamavati, Sajad Behzadian, Kourosh Department of Computer Science Imam Reza International University Mashhad Iran MS of Software Engineering Information and Communication Technology Unit Mashhad Municipality Fire and Safety Services Organization Mashhad Iran Big Data Lab Imam Reza International University Mashhad Iran Institute for Nanomaterials Advanced Technologies and Innovation Technical University of Liberec Liberec46117 Czech Republic Tallinn10615 Estonia Department of Pathology Microbiology and Immunology School of Veterinary Medicine University of California Davis95616 United States Department of Urban and Regional Planning San Jose State University San Jose95192 United States Faculty of Civil and Environmental Engineering Gdansk University of Technology Narutowicza Street 11/12 80-233 Gdansk Poland Tecnologico de Monterrey Escuela de Ingeniería y Ciencias Monterrey Mexico School of Computing and Engineering University of West London London United Kingdom

Accurate and efficient diagnosis of COVID-19 remains a significant challenge due to the limitations of current detection methods, such as blood tests and chest scans, which can be time-consuming and error-prone. This study aims to compare the performance of basic and hybrid data mining algorithms in diagnosing COVID-19, using blood test results and clinical information to identify the most effective approach. A dataset of 200 records from suspected and infected COVID-19 patients, with 23 characteristics and one diagnostic class, was analysed. Nine data mining algorithms were tested: four basic algorithms (Naive Bayes, Support Vector Machine, Decision Tree, K-Nearest Neighbor) and five hybrid algorithms (Random Forest, AdaBoost, Majority Voting, XGBoost, Bagging). The study also integrated Response Surface Methodology (RSM) and Adaptive-Network-based Fuzzy Inference System (ANFIS) to enhance model performance. The Bagging algorithm demonstrated superior performance with an accuracy of 88%, sensitivity of 74%, and F-criterion of 78%. The integration of RSM and ANFIS further showed that a smart model could be developed for efficient pandemic crisis management, achieving up to 100% accuracy when considering key factors like AST, Albumin, and CRP. The findings suggest that Bagging and hybrid data mining algorithms can significantly improve COVID-19 detection, reducing time and errors in identifying exposed individuals. The study highlights the potential of combining machine learning techniques with RSM-ANFIS models for effective pandemic management and decision-making in medical settings. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.

关键词： Support vector machines

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A 3D Memristive Cubic Map with Dual Discrete Memristors: Design, Implementation, and Application in Image Encryption

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IEEE Transactions on Circuits and Systems for Video Technology 2025年

作者： Gao, Suo Iu, Herbert Ho-Ching Erkan, Ugur Simsek, Cemaleddin Toktas, Abdurrahim Cao, Yinghong Wu, Rui Mou, Jun Li, Qi Wang, Chunpeng Dalian Polytechnic University School of Information Science and Engineering Dalian116034 China The University of Western Australia School of Electrical Electronic and Computer Engineering Perth6009 Australia Faculty of Engineering Electrical and Electronics Engineering Respectively Karamanoglu Mehmetbey University Karaman70200 Turkey Ankara University Engineering Faculty Department of Artificial Intelligence and Data Engineering Ankara06830 Turkey Harbin Institute of Technology School of Computer Science and Technology Harbin150001 China Key Laboratory of Computing Power Network and Information Security Ministry of Education Shandong Computer Science Center National Supercomputer Center in Jinan Shandong Provincial Key Laboratory of Computer Networks Shandong Fundamental Research Center for Computer Science Jinan250000 China

Discrete chaotic systems based on memristors exhibit excellent dynamical properties and are more straightforward to implement in hardware, making them highly suitable for generating cryptographic keystreams. However, most existing memristor-based chaotic systems rely on a single memristor. This paper introduces a novel discrete chaotic system employing dual memristors, named the 3D memristive cubic map with dual discrete memristors (3D-MCM). The 3D-MCM system demonstrates richer and more intricate dynamical behaviors compared to its single-memristor counterparts, as verified through bifurcation diagrams, Lyapunov exponent spectra, and complexity analyses. Notably, the system exhibits coexisting attractors, substantially enhancing its dynamical complexity. Hardware implementation of the 3D-MCM attractors confirms its feasibility for industrial applications. To illustrate the system's potential in encryption tasks, this study integrates the quaternary-based permutation and dynamic emanating diffusion (QPDED-IE) scheme for image encryption with the *** results demonstrate that the QPDED-IE scheme based on the 3D-MCM exhibits strong diffusion and confusion properties, effectively resisting cryptanalytic attacks. © 1991-2012 IEEE.

关键词： Bifurcation (mathematics)

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Deep Graph Reinforcement Learning for UAV-Enabled Multi-User Secure Communications

引用

IEEE Transactions on Mobile computing 2025年

作者： Tang, Xiao Zhao, Kexin Shen, Chao Du, Qinghe Wang, Yichen Niyato, Dusit Han, Zhu Research & Development Institute Northwestern Polytechnical University Shenzhen518063 China National Key Laboratory of Wireless Communications Chengdu611731 China State Key Laboratory of Intelligent Game Taicang215400 China Northwestern Polytechinical University School of Electronics and Information Xi'an710072 China Xi'an Jiaotong University Faculty of Electronics and Information Engineering Xi'an710049 China Nanyang Technological University College of Computing and Data Science Singapore University of Houston Department of Electrical and Computer Engineering Houston77004 United States Kyung Hee University Department of Computer Science and Engineering Seoul446-701 Korea Republic of

While unmanned aerial vehicles (UAVs) with flexible mobility are envisioned to enhance physical layer security in wireless communications, the efficient security design that adapts to such high network dynamics is rather challenging. The conventional approaches extended from optimization perspectives are usually quite involved, especially when jointly considering factors in different scales such as deployment and transmission in UAV-related scenarios. In this paper, we address the UAV-enabled multi-user secure communications by proposing a deep graph reinforcement learning framework. Specifically, we reinterpret the security beamforming as a graph neural network (GNN) learning task, where mutual interference among users is managed through the message-passing mechanism. Then, the UAV deployment is obtained through soft actor-critic reinforcement learning, where the GNN-based security beamforming is exploited to guide the deployment strategy update. Simulation results demonstrate that the proposed approach achieves near-optimal security performance and significantly enhances the efficiency of strategy determination. Moreover, the deep graph reinforcement learning framework offers a scalable solution, adaptable to various network scenarios and configurations, establishing a robust basis for information security in UAV-enabled communications. © 2002-2012 IEEE.

关键词： Deep reinforcement learning

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Auction Theory and Game Theory Based Pricing of Edge computing Resources: A Survey

引用

IEEE Internet of Things Journal 2025年

作者： Yu, Jiguo Liu, Shun Zou, Yifei Wang, Guijuan Hu, Chunqiang University of Electronic Science and Technology of China School of Information and Software Engineering Chengdu610054 China Qilu University of Technology Big Data Institute Jinan250353 China Qufu Normal University School of Computer Science Shandong Rizhao China Shandong University School of Computer Science and Technology Shandong Qingdao266237 China Key Laboratory of Computing Power Network and Information Security Ministry of Education Shandong Computer Science Center Jinan250353 China Shandong Fundamental Research Center for Computer Science Shandong Provincial Key Laboratory of Computer Networks Jinan250353 China Chongqing University School of Big Data and Software Engineering Chongqing400044 China

The proliferation of Internet of Things (IoT) devices and edge computing applications has heightened the demand for efficient resource allocation and pricing mechanisms. Effective pricing strategies play a crucial role in optimizing resource utilization, reducing latency, and ensuring fair resource distribution among users. Both auction theory and game theory have emerged as fundamental economic frameworks for designing pricing mechanisms in edge computing. This paper presents a comprehensive survey of pricing strategies that leverage both auction and game theory, systematically categorizing existing research based on auction mechanisms and game-theoretic models. Unlike previous surveys that focus solely on auction-based pricing, this work integrates game-theoretic perspectives, providing a holistic analysis of strategic interactions in edge computing resource allocation. Furthermore, we discuss key challenges, emerging trends, and future research directions aimed at enhancing efficiency, fairness, and privacy protection in cloud-edge collaborative computing environments. © 2014 IEEE.

关键词： Mobile edge computing

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Unsupervised Feature Disentanglement and Augmentation Network for One-class Face Anti-spoofing

arXiv

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arXiv 2025年

作者： Huang, Pei-Kai Chong, Jun-Xiong Hsu, Ming-Tsung Hsu, Fang-Yu Lin, Yi-Ting Chien, Kai-Heng Shao, Hao-Chiang Hsu, Chiou-Ting Institute of Data Science and Information Computing National Chung Hsing University Taichung City402204 Taiwan Department of Computer Science National Tsing Hua University Taiwan

Face anti-spoofing (FAS) techniques aim to enhance the security of facial identity authentication by distinguishing authentic live faces from deceptive attempts. While two-class FAS methods risk overfitting to training attacks to achieve better performance, one-class FAS approaches handle unseen attacks well but are less robust to domain information entangled within the liveness features. To address this, we propose an Unsupervised Feature Disentanglement and Augmentation Network (UFDANet), a one-class FAS technique that enhances generalizability by augmenting face images via disentangled features. The UFDANet employs a novel unsupervised feature disentangling method to separate the liveness and domain features, facilitating discriminative feature learning. It integrates an out-of-distribution liveness feature augmentation scheme to synthesize new liveness features of unseen spoof classes, which deviate from the live class, thus enhancing the representability and discriminability of liveness features. Additionally, UFDANet incorporates a domain feature augmentation routine to synthesize unseen domain features, thereby achieving better generalizability. Extensive experiments demonstrate that the proposed UFDANet outperforms previous one-class FAS methods and achieves comparable performance to state-of-the-art two-class FAS methods. Copyright © 2025, The Authors. All rights reserved.

关键词： Feature extraction

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