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Semi-Supervised Skin Lesion Segmentation with Learning Model Confidence

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Semi-Supervised Skin Lesion Segmentation with Learning Model...

IEEE International Conference on Acoustics, Speech and Signal processing

作者： Zhiqiang Xie Enmei Tu Hao Zheng Yun Gu Jie Yang Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Shanghai China Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China

ISBN: (纸本)9781728176055;9781728176062

Segmentation of skin lesions is important for disease diagnoses and treatment planning. Over the years, semi-supervised methods using pseudo labels have boosted the segmentation performance with limited labeled data and abundant unlabeled data. However, the unreliable targets in pseudo labels might lead to meaningless guidance for unlabeled data. In this paper, to solve this issue, we propose a novel confidence aware semi-supervised learning method based on a mean teacher scheme. Concretely, we design a confidence module to predict the model confidence guided by the True Class Probability. Then in the mean teacher framework, the student model gradually learns trustworthy targets from teacher model. To further improve the segmentation quality, we fine-tune the student model with reliable content in pseudo labels. We conduct extensive experiments on 2018 ISIC skin lesion segmentation dataset and our method outperforms other state-of-the-art semi-supervised approaches.

关键词： Conferences Semisupervised learning Signal processing Predictive models Skin Planning Lesions

BREAK: BRONCHI RECONSTRUCTION BY GEODESIC TRANSFORMATION AND SKELETON EMBEDDING

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arXiv 2022年

作者： Yu, Weihao Zheng, Hao Zhang, Minghui Zhang, Hanxiao Sun, Jiayuan Yang, Jie Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University China Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China Department of Respiratory and Critical Care Medicine Department of Respiratory Endoscopy Shanghai Chest Hospital Shanghai Engineering Research Center of Respiratory Endoscopy China

Airway segmentation is critical for virtual bronchoscopy and computer-aided pulmonary disease analysis. In recent years, convolutional neural networks (CNNs) have been widely used to delineate the bronchial tree. However, the segmentation results of the CNN-based methods usually include many discontinuous branches, which need manual repair in clinical use. A major reason for the breakages is that the appearance of the airway wall can be affected by the lung disease as well as the adjacency of the vessels, while the network tends to overfit these special patterns in the training set. To learn robust features for these areas, we design a multi-stage framework that adopts the geodesic distance transform to capture the intensity changes between airway lumen and wall. Another reason for the breakages is the intra-class imbalance. Since the volume of the peripheral bronchi may be much smaller than the large branches in an input patch, the common segmentation loss is not sensitive to the breakages among the distal branches. Therefore, in this paper, a breakage-sensitive regularization term is designed and can be easily combined with other loss functions. Extensive experiments are conducted on publicly available datasets. Compared with state-of-the-art methods, our framework can detect more branches while maintaining competitive segmentation performance. Copyright © 2022, The Authors. All rights reserved.

关键词： Computer aided analysis

Diabetic Retinopathy Lesion Segmentation Using Deep Multi-Scale Framework

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SSRN

SSRN 2023年

作者： Guo, Tianjiao Yang, Jie Yu, Qi Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China Institute of Image Processing and Pattern Recognition Department of Automation Shanghai Jiao Tong University Shanghai China School of Biomedical Engineering Shanghai Jiao Tong Univeristy Shanghai China Department of Ophthalmology Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China National Clinical Research Center for Eye Diseases Shanghai China

The segmentation of diabetic retinopathy (DR) lesions is important for large-scale screening using color fundus photography (CFP) images. The difficulty of this task is that the DR lesions have various sizes, shapes, and intensities. Traditional handcrafted feature-based approaches are unsatisfactory, and recent deep-learning-based approaches ignore the features of DR lesions. In this paper, we propose a segmentation approach that segments four typical DR lesions simultaneously based on convolutional neural networks (CNN). The raw CFP image is first pre-processed and resized to different sizes. A set of fully convolutional neural networks (FCNs) with various input sizes are then trained to extract the lesions from different scales. An auxiliary CNN is then introduced to fuse the output from these FCNs and refine the segmentation *** conducted our experiments on one local dataset and three public datasets including IDRiD, DDR, and DIARETDB1. The results of the area under the precision-recall-curve (AUPR) show that our approach achieves competitive *** improvement in performance indicates that this approach is beneficial to DR lesion segmentation and has potential in other segmentation tasks. © 2023, The Authors. All rights reserved.

关键词： Convolution

Colonoscopic image Synthesis For Polyp Detector Enhancement Via Gan And Adversarial Training

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Colonoscopic Image Synthesis For Polyp Detector Enhancement ...

IEEE International Symposium on Biomedical Imaging

作者： Fan He Sizhe Chen Shuaiyi Li Lu Zhou Haiqin Zhang Haixia Peng Xiaolin Huang Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Digestive Endoscopy Center Tongren Hospital Shanghai Jiao Tong University School of Medicine Institute of Medical Robotics Shanghai Jiao Tong University

Computer-aided polyp detection system powered by deep neural networks has achieved high performance but also suffers from data insufficiency. To address this problem, recent researches focus on synthesizing new colonoscopic images by Generative Adversarial Network (GAN). However, the synthesized images follow the same distribution as that of the training dataset, which limits the performance of the detectors re-trained on it. Recent studies show that adversarial examples can expand the data distribution and thus adversarial training can effectively improve the robustness of deep neural networks. Inspired by these two factors, this paper proposes a data augmentation framework to directly produce false negative colonoscopic images via GAN and the adversarial attack. The synthesized polyps are natural and experiments on three popular detectors show that compared with using GAN alone, producing false negative images by the adversarial attack can further improve the performance of the re-trained detectors.

关键词： Training image synthesis Neural networks Deep architecture Detectors Generative adversarial networks Robustness

Stereo endoscopic image super-resolution using disparity-constrained parallel attention

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arXiv 2020年

作者： Zhang, Tianyi Gu, Yun Huang, Xiaolin Tu, Enmei Yang, Jie Institute of Image Processing and Pattern Recognition Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China

With the popularity of stereo cameras in computer assisted surgery techniques, a second viewpoint would provide additional information in surgery. However, how to effectively access and use stereo information for the super-resolution (SR) purpose is often a challenge. In this paper, we propose a disparity-constrained stereo super-resolution network (DCSSRnet) to simultaneously compute a super-resolved image in a stereo image pair. In particular, we incorporate a disparity-based constraint mechanism into the generation of SR images in a deep neural network framework with an additional atrous parallax-attention modules. Experiment results on laparoscopic images demonstrate that the proposed framework outperforms current SR methods on both quantitative and qualitative evaluations. Our DCSSRnet provides a promising solution on enhancing spatial resolution of stereo image pairs, which will be extremely beneficial for the endoscopic surgery. Copyright © 2020, The Authors. All rights reserved.

关键词： Optical resolving power

Generalization properties of hyper-RKHS and its applications

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The Journal of Machine Learning Research

The Journal of Machine Learning Research 2021年第1期22卷 6220-6257页

作者： Fanghui Liu Lei Shi Xiaolin Huang Jie Yang Johan A.K. Suykens Department of Electrical Engineering ESAT-STADIUS KU Leuven Leuven Belgium Shanghai Key Laboratory for Contemporary Applied Mathematics School of Mathematical Sciences Fudan University Shanghai China Institute of Image Processing and Pattern Recognition Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China

This paper generalizes regularized regression problems in a hyper-reproducing kernel Hilbert space (hyper-RKHS), illustrates its utility for kernel learning and out-of-sample extensions, and proves asymptotic convergence results for the introduced regression models in an approximation theory view. Algorithmically, we consider two regularized regression models with bivariate forms in this space, including kernel ridge regression (KRR) and support vector regression (SVR) endowed with hyper-RKHS, and further combine divide-and-conquer with Nyström approximation for scalability in large sample cases. This framework is general: the underlying kernel is learned from a broad class, and can be positive definite or not, which adapts to various requirements in kernel learning. Theoretically, we study the convergence behavior of regularized regression algorithms in hyper-RKHS and derive the learning rates, which goes beyond the classical analysis on RKHS due to the non-trivial independence of pairwise samples and the characterisation of hyper-RKHS. Experimentally, results on several benchmarks suggest that the employed framework is able to learn a general kernel function form an arbitrary similarity matrix, and thus achieves a satisfactory performance on classification tasks.

关键词： hyper-RKHS approximation theory kernel learning out-of-sample extensions

Fast learning in reproducing kernel Kreĭn spaces via signed measures

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arXiv 2020年

作者： Liu, Fanghui Huang, Xiaolin Chen, Yingyi Suykens, Johan A.K. KU Leuven Belgium Institute of Image Processing and Pattern Recognition Institute of Medical Robotics Shanghai Jiao Tong University China

In this paper, we attempt to solve a long-lasting open question for non-positive definite (non-PD) kernels in machine learning community: can a given non-PD kernel be decomposed into the difference of two PD kernels (termed as positive decomposition)? We cast this question as a distribution view by introducing the signed measure, which transforms positive decomposition to measure decomposition: a series of non-PD kernels can be associated with the linear combination of specific finite Borel measures. In this manner, our distribution-based framework provides a sufficient and necessary condition to answer this open question. Specifically, this solution is also computationally implementable in practice to scale non-PD kernels in large sample cases, which allows us to devise the first random features algorithm to obtain an unbiased estimator. Experimental results on several benchmark datasets verify the effectiveness of our algorithm over the existing methods. Copyright © 2020, The Authors. All rights reserved.

关键词： Machine learning

FDFlowNet: Fast optical flow estimation using a deep lightweight network

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arXiv 2020年

作者： Kong, Lingtong Yang, Jie Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University China Institute of Medical Robotics Shanghai Jiao Tong University China

Significant progress has been made for estimating optical flow using deep neural networks. Advanced deep models achieve accurate flow estimation often with a considerable computation complexity and time-consuming training processes. In this work, we present a lightweight yet effective model for real-time optical flow estimation, termed FDFlowNet (fast deep flownet). We achieve better or similar accuracy on the challenging KITTI and Sintel benchmarks while being about 2 times faster than PWC-Net. This is achieved by a carefully-designed structure and newly proposed components. We first introduce an U-shape network for constructing multi-scale feature which benefits upper levels with global receptive field compared with pyramid network. In each scale, a partial fully connected structure with dilated convolution is proposed for flow estimation that obtains a good balance among speed, accuracy and number of parameters compared with sequential connected and dense connected structures. Experiments demonstrate that our model achieves state-of-the-art performance while being fast and lightweight. Copyright © 2020, The Authors. All rights reserved.

关键词： Optical flows

Weakly Supervised Deep Learning for Breast Cancer Segmentation with Coarse Annotations 23rd

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Weakly Supervised Deep Learning for Breast Cancer Segmentati...

23rd International Conference on medical image Computing and Computer-Assisted Intervention, MICCAI 2020

作者： Zheng, Hao Zhuang, Zhiguo Qin, Yulei Gu, Yun Yang, Jie Yang, Guang-Zhong Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University Shanghai China School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China Department of Radiology Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

ISBN: (纸本)9783030597184

Cancer lesion segmentation plays a vital role in breast cancer diagnosis and treatment planning. As creating labels for large medical image datasets can be time-consuming, laborious and error prone, a framework is proposed in this paper by using coarse annotations generated from boundary scribbles for training deep convolutional neural networks. These coarse annotations include locations of lesions but are lack of accurate information about boundaries. To mitigate the negative impact of annotation errors, we propose an adaptive weighted constrained loss that can change the weight of the task-specific penalty term according to the learning process. To impose further supervision about the boundaries, uncertainty-based boundary maps are generated, which can provide better descriptions for the blurry boundaries. Validation on a dataset containing 154 MRI scans has shown an average Dice coefficient of 82.25 %, which is comparable to results from fine annotations, demonstrating the efficacy of the proposed approach. © 2020, Springer Nature Switzerland AG.

关键词： Diagnosis