High-throughput proteomics based on mass spectrometry（MS） analysis has permeated biomedical science and propelled numerous research projects. p Find 3 is a database search engine for high-speed and in-depth proteomi...
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High-throughput proteomics based on mass spectrometry（MS） analysis has permeated biomedical science and propelled numerous research projects. p Find 3 is a database search engine for high-speed and in-depth proteomics data analysis. p Find 3 features a swift open search workflow that is adept at uncovering less obvious information such as unexpected modifications or mutations that would have gone unnoticed using a conventional data analysis pipeline. In this protocol, we provide step-by-step instructions to help users mastering various types of data analysis using p Find 3 in conjunction with p Parse for data pre-processing and if needed, p Quant for quantitation. This streamlined p Parse-p Findp Quant workflow offers exceptional sensitivity, precision, and speed. It can be easily implemented in any laboratory in need of identifying peptides, proteins, or post-translational modifications, or of quantitation based on15N-labeling, SILAC-labeling, or TMT/i TRAQ labeling.
In recent years, reinforcement learning, which enables robots to learn previously missing abilities, plays an increasingly important role in robotics, such as learning hard-to-code behaviors or optimizing problems wit...
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The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bott...
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