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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Jiang, Hanjing Wang, Meineng Zhang, Luping Huang, Yu-An Li, Yangyuan Huang, Yabing Huazhong University of Science and Technology Key Laboratory of Image Information Processing and Intelligent Control Education Ministry of China Institute of Artificial Intelligence School of Artificial Intelligence and Automation Hubei Wuhan430074 China China University of Mining and Technology School of Computer Science and Technology Xuzhou221116 China Yichun University School of Mathematics and Computer Science Yichun336000 China East China University of Technology School of Information Engineering Nanchang330013 China Northwestern Polytechnical University School of Computer Science Xi'an710129 China Renmin Hospital Wuhan University Department of Pathology Wuhan430060 China

ISBN: (纸本)9798350386226

The advent of single-cell RNA sequencing (scRNA-seq) has facilitated the acquisition of high-resolution data regarding cell heterogeneity across various tissues. A fundamental and critical step in the analysis of scRNA-seq data is cell type identification. An appropriate graph construction strategy can reflect the topological structure between cells and allows for detailed exploration of the relationships between cells and genes. Given the sparsity of scRNA-seq data and the pronounced noise generated by shallow sequencing, choosing an appropriate graph construction strategy has become a significant challenge. In this paper, we propose a single-cell clustering method, named Sc-PNNMF, based on structural perturbation of nonnegative matrix factorization. Sc-PNNMF employs a structural perturbation algorithm to optimize the gene expression matrix. The optimized matrix guides the matrix factorization process, effectively overcoming the impact of data sparsity and significant noise in gene expression data on the graph construction strategy. We compared the clustering abilities of Sc-PNNMF with five other methods on ten real datasets. © 2024 IEEE.

关键词： Non-negative matrix factorization

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Deep transfer learning-based decoder calibration for intracortical brain-machine interfaces

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Computers in Biology and Medicine 2025年第Pt A期192卷 110231-110231页

作者： Li, Xiao Dong, Xianxin Wang, Jun Mao, Haodong Tu, Xikai Li, Wei He, Jiping Li, Qiang Zhang, Peng Hubei Key Laboratory of Modern Manufacturing Quantity Engineering School of Mechanical Engineering Hubei University of Technology Wuhan430068 China Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Hubei Wuhan China MoE Key Laboratory for Biomedical Photonics Collaborative Innovation Center for Biomedical Engineering School of Engineering Sciences Huazhong University of Science and Technology Hubei Wuhan China The Key Laboratory of Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Hubei Wuhan China Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of Technology Beijing China

Intracortical brain-machine interfaces (iBMIs) aim to establish a communication path between the brain and external devices. However, in the daily use of iBMIs, the non-stationarity of recorded neural signals necessitates frequent recalibration of the iBMI decoder to maintain decoding performance, which requires collecting and labeling a large amount of new data. To address this challenge and minimize the time needed for decoder recalibration, we proposed an active learning domain adversarial neural network (AL-DANN). This model leveraged a substantial volume of historical data alongside a small amount of current data (four samples per category) to calibrate the decoder. By incorporating domain adversarial and active learning strategies, the model effectively transferred knowledge from historical data to new data, reducing the demand for new samples. We validated the proposed method using neural signals recorded from three monkeys performing different movements in a classification task or a regression task. The results showed that the AL-DANN outperformed existing state-of-the-art methods. Impressively, it required only four new samples per category for decoder recalibration, leading to a recalibration time reduction of over 80 %. To our knowledge, this is the first study to incorporate deep transfer learning into iBMI decoder calibration, highlighting the significant potential of applying deep learning technologies in iBMIs. © 2025

关键词： Adversarial machine learning

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Model Predictive control Method for Multi-motor System with Dead Zone

Model Predictive Control Method for Multi-motor System with ...

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作者： Genglin Fan Xiuchuan Tang Yi Shen Linan Deng China-EU Institute for Clean and Renewable Energy Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology School of Mechanical Science and Engineering Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology School of Artificial Intelligence and Automation Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology

The multi-motor system shows excellent performance in achieving high-precision control in the applications with large load inertia,such as large-aperture telescopes and highprecision processing machine ***,the non-linearity of gear transmission remains a key challenge that will cause the fluctuation of angular velocity and position of the load in the multi-motor *** order to compensate for the nonlinearity in the multi-motor system,this paper introduces a deadzone model into the spring-damper dynamics of the multi-motor system,based on which a model predictive control(MPC) method is proposed to control the angular velocity and angle of the *** optimization target of the proposed controller is to limit the fluctuations of input torque as much as *** effectiveness of the dead-zone based dynamic model and the MPC method are verified by simulation.

关键词： multi-motor system MPC dead zone

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Data-Driven Discovery of Stochastic Differential Equations

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engineering 2022年第10期17卷 244-252页

作者： Yasen Wang Huazhen Fang Junyang Jin Guijun Ma Xin He Xing Dai Zuogong Yue Cheng Cheng Hai-Tao Zhang Donglin Pu Dongrui Wu Ye Yuan Jorge Gonçalves Jürgen Kurths Han Ding School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074China Department of Mechanical Engineering University of KansasLawrenceKS 66045USA HUST-Wuxi Research Institute Wuxi 214174China Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and AutomationHuazhong University of Science and TechnologyWuhan 430074China Department of Plant Sciences University of CambridgeCambridge CB23EAUK Luxembourg Centre for Systems Biomedicine University of LuxembourgBelvaux 4367Luxembourg Department of Physics Humboldt University of BerlinBerlin 12489Germany Department of Complexity Science Potsdam Institute for Climate Impact ResearchPotsdam 14473Germany

Stochastic differential equations(SDEs)are mathematical models that are widely used to describe complex processes or phenomena perturbed by random noise from different *** identification of SDEs governing a system is often a challenge because of the inherent strong stochasticity of data and the complexity of the system’s *** practical utility of existing parametric approaches for identifying SDEs is usually limited by insufficient data *** study presents a novel framework for identifying SDEs by leveraging the sparse Bayesian learning(SBL)technique to search for a parsimonious,yet physically necessary representation from the space of candidate basis *** importantly,we use the analytical tractability of SBL to develop an efficient way to formulate the linear regression problem for the discovery of SDEs that requires considerably less time-series *** effectiveness of the proposed framework is demonstrated using real data on stock and oil prices,bearing variation,and wind speed,as well as simulated data on well-known stochastic dynamical systems,including the generalized Wiener process and Langevin *** framework aims to assist specialists in extracting stochastic mathematical models from random phenomena in the natural sciences,economics,and engineering fields for analysis,prediction,and decision making.

关键词： Data-driven method System identification Sparse Bayesian learning Stochastic differential equations Random phenomena

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Prognostic Prediction for Non-small-Cell Lung Cancer Based on Deep Neural Network and Multimodal Data 17th

Prognostic Prediction for Non-small-Cell Lung Cancer Based o...

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17th International Conference on intelligent Computing, ICIC 2021

作者： Zhang, Zhong-Si Xu, Fei Jiang, Han-Jing Chen, Zhan-Heng Key Laboratory of Image Information Processing and Intelligent Control of Education Ministry of China Institute of Artificial Intelligence School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Institute of Machine Learning and Systems Biology School of Electronics and Information Engineering Tongji University No. 4800 Caoan Road Shanghai201804 China

ISBN: (纸本)9783030845315

Non-small-cell lung cancer (NSCLC) is the most common lung cancer with poor prognosis. Prognostic prediction is significant in improving the prognosis of NSCLC patients. Clinical information and multi-omics data including gene expression, miRNA, copy number variations, and DNA methylation are closely related to NSCLC prognosis. In this study, we propose a deep neural network to conduct prognostic prediction for NSCLC patients based on all five types of data. Given the high dimensional features of the omics data, past works reduce the feature dimension by regression analysis or correlation sorting algorithms. A shortcoming of these methods is that only a small number of features are considered. To overcome it, we propose a convolution neural network-based feature transformation method, which considers all features and extracts the abstract representations of the omics data. Based on the representations, we predict the five-year survival status of NSCLC patients. The results show that our method achieves a more precise prediction than previous work, with the areas under the curve improved from 0.8163 to 0.8508 and the accuracy improved from 0.7544 to 0.8096. © 2021, Springer Nature Switzerland AG.

关键词： Forecasting

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T-TIME: Test-Time Information Maximization Ensemble for Plug-and-Play BCIs

arXiv

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arXiv 2024年

作者： Li, Siyang Wang, Ziwei Luo, Hanbin Ding, Lieyun Wu, Dongrui Ministry of Education Key Laboratory of Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Shenzhen Huazhong University of Science and Technology Research Institute Shenzhen China Henan Key Laboratory of Brain Science and Brain Computer Interface Technology School of Electrical and Information Engineering Zhengzhou University China School of Civil and Hydraulic Engineering Huazhong University of Science and Technology Wuhan430074 China

Objective: An electroencephalogram (EEG)-based brain-computer interface (BCI) enables direct communication between the human brain and a computer. Due to individual differences and non-stationarity of EEG signals, such BCIs usually require a subject-specific calibration session before each use, which is time-consuming and user-unfriendly. Transfer learning (TL) has been proposed to shorten or eliminate this calibration, but existing TL approaches mainly consider offline settings, where all unlabeled EEG trials from the new user are available. Methods: This paper proposes Test-Time Information Maximization Ensemble (T-TIME) to accommodate the most challenging online TL scenario, where unlabeled EEG data from the new user arrive in a stream, and immediate classification is performed. T-TIME initializes multiple classifiers from the aligned source data. When an unlabeled test EEG trial arrives, T-TIME first predicts its labels using ensemble learning, and then updates each classifier by conditional entropy minimization and adaptive marginal distribution regularization. Our code is publicized. Results: Extensive experiments on three public motor imagery based BCI datasets demonstrated that T-TIME outperformed about 20 classical and state-of-the-art TL approaches. Significance: To our knowledge, this is the first work on test time adaptation for calibration-free EEG-based BCIs, making plug-and-play BCIs possible. © 2024, CC BY.

关键词： Calibration

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Memory Analysis for Memristors and Memristive Recurrent Neural Networks

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IEEE/CAA Journal of Automatica Sinica 2020年第1期7卷 96-105页

作者： Gang Bao Yide Zhang Zhigang Zeng Key Laboratory of Cascaded Hydropower Stations Operation and Control Electrical Engineering and New EnergyChina Three Gorges UniversityYichang 443002and Hubei Key Laboratory of Applied Mathematics(Hubei University)Wuhan 430074China Department of Medical Engineering California Institute of TechnologyPasadenaCalifornia 91125 USA School of Artificial Intelligence and Automation Huazhong University of Science and Technologyand also with the Key Laboratory of Image Processing and Intelligent Control of Education Ministry of ChinaWuhan 430074China

Traditional recurrent neural networks are composed of capacitors, inductors, resistors, and operational *** neural networks are constructed by replacing resistors with memristors. This paper focuses on the memory analysis,i.e. the initial value computation, of memristors. Firstly, we present the memory analysis for a single memristor based on memristors’ mathematical models with linear and nonlinear ***, we present the memory analysis for two memristors in series and parallel. Thirdly, we point out the difference between traditional neural networks and those that are memristive. Based on the current and voltage relationship of memristors, we use mathematical analysis and SPICE simulations to demonstrate the validity of our methods.

关键词： Dopant drift memory memristive neural networks memristor

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Channel Reflection: Knowledge-Driven Data Augmentation for Eeg-Based Bcis

SSRN

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SSRN 2024年

作者： Wang, Ziwei Li, Siyang Luo, Jingwei Liu, Jiajing Wu, Dongrui Key Laboratory of the Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China Shenzhen Huazhong University of Science and Technology Research Institute Shenzhen518063 China China Electronic System Technology Co. Ltd. Beijing100089 China School of Civil and Hydraulic Engineering Huazhong University of Science and Technology Wuhan430074 China

A brain-computer interface (BCI) enables direct communication between the human brain and external devices. Electroencephalography (EEG) based BCIs are currently the most popular for able-bodied users. To increase user-friendliness, usually a small amount of user-specific EEG data are used for calibration, which may not be enough to develop a pure data-driven decoding model. To cope with this typical calibration data shortage challenge in EEG-based BCIs, this paper proposes a parameter-free channel reflection (CR) data augmentation approach that incorporates prior knowledge on the channel distributions of different BCI paradigms in data augmentation. Experiments on eight public EEG datasets across four different BCI paradigms (motor imagery, steady-state visual evoked potential, P300, and seizure classifications) using different decoding algorithms demonstrated that: 1) CR is effective, i.e., it can noticeably improve the classification accuracy;2) CR is robust, i.e., it consistently outperforms other data augmentation approaches in the literature;and, 3) CR is flexible, i.e., it can be combined with other data augmentation approaches to further increase the performance. We suggest that data augmentation approaches like CR should be an essential step in EEG-based BCIs. Our code is available online. © 2024, The Authors. All rights reserved.

关键词： Electroencephalography

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Sparse Prior Is Not All You Need: When Differential Directionality Meets Saliency Coherence for Infrared Small Target Detection

arXiv

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arXiv 2024年

作者： Zhou, Fei Fu, Maixia Qian, Yulei Yang, Jian Dai, Yimian Ministry of Education Henan Key Laboratory of Grain Photoelectric Detection and Control Henan University of Technology Zhengzhou China Nanjing Marine Radar Institute Nanjing China PCA Lab Key Lab of Intelligent Perception and Systems for High-Dimensional Information of Ministry of Education Jiangsu Key Lab of Image and Video Understanding for Social Security School of Computer Science and Engineering Nanjing University of Science and Technology Nanjing China

Infrared small target detection is crucial for the efficacy of infrared search and tracking systems. Current tensor decomposition methods emphasize representing small targets with sparsity but struggle to separate targets from complex backgrounds due to insufficient use of intrinsic directional information and reduced target visibility during decomposition. To address these challenges, this study introduces a Sparse Differential Directionality prior (SDD) framework. SDD leverages the distinct directional characteristics of targets to differentiate them from the background, applying mixed sparse constraints on the differential directional images and continuity difference matrix of the temporal component, both derived from Tucker decomposition. We further enhance target detectability with a saliency coherence strategy that intensifies target contrast against the background during hierarchical decomposition. A Proximal Alternating Minimization-based (PAM) algorithm efficiently solves our proposed model. Experimental results on several real-world datasets validate our method’s effectiveness, outperforming ten state-of-the-art methods in target detection and clutter suppression. Our code is available at https://***/GrokCV/SDD. Copyright © 2024, The Authors. All rights reserved.

关键词： Tensors

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Underwater image enhancement via histogram similarity-oriented color compensation complemented by multiple attribute adjustment

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intelligent Marine Technology and Systems 2023年第1期1卷 1-15页

作者： Wang, Hao Frery, Alejandro C. Li, Mingjie Ren, Peng College of Control Science and Engineering China University of Petroleum (East China) Qingdao China College of Mathematics and Statistics Victoria University of Wellington Wellington New Zealand Key Laboratory of Intelligent Perception and Image Understanding of the Ministry of Education Xidian University Xi’an China South China Sea Institute of Planning and Environmental Research State Oceanic Administration Guangzhou China College of Oceanography and Space Informatics China University of Petroleum (East China) Qingdao China

Underwater images are often influenced by color casts, low contrast, and blurred details. We observe that images taken in natural settings typically have similar histograms across color channels, while underwater images do not. To improve the natural appearance of an underwater image, it is critical to improve the histogram similarity across its color channels. To address this problem, we develop a histogram similarity-oriented color compensation method that corrects color casts by improving the histogram similarity across color channels in the underwater image. In addition, we apply the multiple attribute adjustment method, including max-min intensity stretching, luminance map-guided weighting, and high-frequency edge mask fusion, to enhance contrast, saturation, and sharpness, effectively addressing problems of low contrast and blurred details and eventually enhancing the overall appearance of underwater images. Particularly, the method proposed in this work is not based on deep learning, but it effectively enhances a single underwater image. Comprehensive empirical assessments demonstrated that this method exceeds state-of-the-art underwater image enhancement techniques. To facilitate public assessment, we made our reproducible code available at https://***/wanghaoupc/UIE_HS2CM2A.

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