Distracted driving is a phenomenon that drivers’ attention points to activities unrelated to normal driving, which leads to the decline of driving operation ability. With the popularity of smart phones, traffic accid...
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The method of generating articulatory animation based on automatic key point detection and style transfer. This paper proposes a system of key-points detection and registration based on image feature space, and uses t...
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In view of the wide variety of plants on the earth, the plant species identification is particularly necessary to protect and preserve biodiversity. In this work, we propose a plant image classification method based o...
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The general single image super-resolution methods mainly extract features from the high-resolution (HR) space by the pre-upscaling step at the beginning of the network or from the low-resolution (LR) space before the ...
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We use a large foundation language model, which is fine-tuned with debate corpora, to develop a robot debater application. To address the limitations of requiring immense computational power in large base language mod...
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Depth estimation plays an important role in robotic perception systems. The self-supervised monocular paradigm has gained significant attention since it can free training from the reliance on depth annotations. Despit...
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Machine unlearning (MU) is to make a well-trained model behave as if it had never been trained on specific data. In today’s over-parameterized models, dominated by neural networks, a common approach is to manually re...
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Deep Neural Networks (DNNs) are susceptible to elaborately designed perturbations, whether such perturbations are dependent or independent of images. The latter one, called Universal Adversarial Perturbation (UAP), is...
Deep Neural Networks (DNNs) are susceptible to elaborately designed perturbations, whether such perturbations are dependent or independent of images. The latter one, called Universal Adversarial Perturbation (UAP), is very attractive for model robustness analysis, since its independence of input reveals the intrinsic characteristics of the model. Relatively, another interesting observation is Neural Collapse (NC), which means the feature variability may collapse during the terminal phase of training. Motivated by this, we propose to generate UAP by attacking the layer where NC phenomenon happens. Because of NC, the proposed attack could gather all the natural images’ features to its surrounding, which is hence called Feature-Gathering UAP (FG-UAP). We evaluate the effectiveness our proposed algorithm on abundant experiments, including untargeted and targeted universal attacks, attacks under limited dataset, and transfer-based black-box attacks among different architectures including Vision Transformers, which are believed to be more robust. After that, we empirically verify the effectiveness of NC's conclusion on UAP by attacking on only 10% of the dataset while keeping comparable performance. Finally, we investigate FG-UAP in the view of NC by analyzing the labels and extracted features of adversarial examples, finding that collapse phenomenon becomes stronger after the model is corrupted. Codes for the project are available at https://***/yzx1213/FG-UAP.
Automatic and precise multi-class vertebrae segmentation from CT images is crucial for various clinical applications. However, due to a lack of explicit consistency constraints, existing methods especially for single-...
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Small interfering RNA (siRNA) is often used for function study and expression regulation of specific genes, as well as the development of small molecule drugs. Selecting siRNAs with high inhibition and low off-target ...
Small interfering RNA (siRNA) is often used for function study and expression regulation of specific genes, as well as the development of small molecule drugs. Selecting siRNAs with high inhibition and low off-target effects from massive candidates is always a great challenge. Increasing experimentally-validated samples can prompt the development of machine-learning-based algorithms, including Support Vector Machine (SVM), Convolutional Neural Network (CNN), and Graph Neural Network (GNN). However, these methods still suffer from limited accuracy and poor generalization in designing potent and specific siRNAs. In this study, we propose a novel approach for siRNA inhibition and off-target effect prediction, named AttSiOff. It combines a self-attention-based siRNA inhibition predictor with an mRNA searching package and an off-target filter. The predictor gives the inhibition score via analyzing the embedding of siRNA and local mRNA sequences, generated from the pre-trained RNA-FM model, as well as other meaningful prior-knowledge-based features. Self-attention mechanism can detect potentially decisive features, which may determine the inhibition of siRNA. It captures global and local dependencies more efficiently than normal convolutions. The tenfold cross-validation results indicate that our model outperforms all existing methods, achieving PCC of 0.81, SPCC of 0.84, and AUC of 0.886. It also reaches better performance of generalization and robustness on cross-dataset validation. In addition, the mRNA searching package could find all mature mRNAs for a given gene name from the GENOMES database, and the off-target filter can calculate the amount of unwanted off-target binding sites, which affects the specificity of siRNA. Experiments on five mature siRNA drugs, as well as a new target gene (AGT), show that AttSioff has excellent convenience and operability in practical applications. · We utilize a pre-trained model to enrich the information of sequence embedding,
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